Evaluation of Frequency of Diabetic Ketoacidosis and Presenting Symptoms in Patients of Diabetes Mellitus Presenting

2021 ◽  
Vol 15 (12) ◽  
pp. 3390-3392
Author(s):  
Shahnaz Noor ◽  
Irum Noor ◽  
Sadia Bashir
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Tertiary Care ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Serum Glucose ◽  
Care Hospital ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Presenting Symptoms

Objective: To evaluate the frequency of diabetic ketoacidosis and presenting symptoms in patients of diabetes mellitus presenting at tertiary care hospital. Material and methods: In this cross sectional study total 145 patients of diabetes were selected from Department of Medicine from April 2020 to November 2020. Inclusion criteria was: un-controlled type II Diabetes Mellitus with HBA1c levels > 8, age between 30-70 years, male or female. Diabetic ketoacidosis was studied in selected patients. Results: Mean age of the patients 49.80 ± 9.38 years. Out of 145 patients, ketoacidosis was found in 30 (21%) patients. Vomiting was the most common (88/60.69%) presenting symptom followed nausea in 59 (40.68%) patients, polyuria 50 (34.48%), polydipsia 41 (28.27%), abdominal pain 32 (22.07%), weight loss 16 (11.03%) and Polyphagia in 8 (5.52%) patients. Ketoacidosis was found in 15 (23.44%) male diabetics and 15 (18.52%) female diabetics. Association of ketoacidosis with gender was not significant (P = 0.468). Conclusion: Findings of this study showed a higher rate of diabetic ketoacidosis. Vomiting was the most common presenting symptom. Most of the patients were between 30-50 years. No gender difference was found in development of diabetic ketoacidosis. Most of the patients of diabetic ketoacidosis had family history of diabetes. Keywords: Ketone, Ketoacidosis, fasting serum glucose, diabetes mellitus, random serum glucose

scholarly journals TYPE II DIABETICS

2016 ◽  
Vol 23 (02) ◽  
pp. 133-137
Author(s):  
Azfar Farogh ◽  
Muhammad Arif Mahmood ◽  
Khalil Ahmad
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Diabetic Ketoacidosis ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Type Ii ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Study Results ◽  
History Of

Objectives: To determine the frequency of diabetic ketoacidosis in type IIdiabetic patients. Study Design: Cross sectional study. Setting: Department of Medicine,Sahiwal Medical College Sahiwal. Period: September 2014 to March 2015. Material andmethod: Permission was taken from Institutional review board and written informed consentwas taken from every patient. Total 189 patients with type II DM (Un-controlled) having Fastingplasma glucose level ≥126mg/dl either male or female having age 35 years to 65 years wereincluded in the study. Results: Total 189 patients with type II diabetes mellitus were includedin this study. Mean age of the 50.09 ± 9.39 years. Male patients were 79 (42%) and femalepatients were 110 (58%). Insignificant association between gander and Ketoacidosis was seen.No association of family history of diabetes mellitus with Ketoacidosis was found. Conclusion:Results of this study showed that male or female can be equally victim of diabetic ketoacidosis.Diabetic ketoacidosis can be develop equally in younger or older age group. No significantdifference for the development of diabetic ketoacidosis was found between obese/non-obeseand patients with family history of diabetes or without family history of diabetes.

scholarly journals SURVEY OF PATTERN OF DRUG INTERACTIONS IN PATIENTS BEING PRESCRIBED ANTI-DIABETIC MEDICATIONS IN A TERTIARY CARE HOSPITAL: PROSPECTIVE CROSS SECTIONAL STUDY

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sujeet A. Divhare ◽  
Satyashil Ingale
Keyword(s):  
Diabetes Mellitus ◽  
Drug Interactions ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Potential Ddis ◽  
Cross Sectional

Background: Potential importance of drug –drug interactions (DDIs) is increasing as polypharmacy becomes more prevalent. Because additional data on the incidence and pattern of potential DDIs among diabetic patients are lacking in India, and supplemental pharmacodynamic or clinical outcome information is needed to address importance of a drug- drug interaction. Aim and objectives: To identify and analyze the pattern of DDIs in patients being prescribed anti-diabetic drugs in a tertiary care hospital. Material and Methods: This prospective cross-sectional study was carried out for a period of three months in 200 Type 2 diabetes mellitus (Type 2 DM) patients who were taking at least one antidiabetic agent during the period of past six months, of any age and either sex admitted in medicine ward of a tertiary care teaching hospital. Only one prescription was included for each patient on his/her 3rd day of hospitalization in the ward. Results: A total of 1217 drugs were prescribed in 200 prescriptions, resulting in an average of 6.1 drugs per prescription. A total of 637 potential DDIs were noted. The majority were seen in middle aged and elderly people. No overall difference was detected in the patients on insulin or metformin therapy taking or not taking additional drugs with the potential to interact. Worse control was found in the group of patients on sulphonylurea therapy taking interacting drugs (P <0.05). This difference was most marked in the group of patients over 60 years of age, who also had the highest intake of potentially interacting drugs (57%; <35 years-37%). Conclusion: Antidiabetic drugs have numerous interactions. A good practice is to use a drug­–drug interaction checker if any questions arise, several are available online. Quality care starts with the clinician obtaining a complete medication list for each patient at the start of each visit. Keywords: diabetes mellitus, drug interactions, hypoglycemic agents, drug therapy, co-morbidity, polypharmacy

scholarly journals Study of awareness of insulin usage in diabetics attending NRI Medical College and General Hospital

2017 ◽  
Vol 7 (1) ◽  
pp. 59
Author(s):  
Jagadeesh A. ◽  
Ravi Shankar K. ◽  
Krishnakanth K.
Keyword(s):  
Insulin Therapy ◽  
Tertiary Care ◽  
Disease Process ◽  
Type Ii Diabetes Mellitus ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Diabetes Treatment ◽  
Cross Sectional ◽  
High Blood Glucose ◽  
Family History Of Diabetes

Background: India had 69.2 million diabetic patients. Insulin is an important part of diabetes treatment, but one-third of patients fail to take their insulin as prescribed, and many adults intentionally skip their doses. Since, diabetes treatment continues for lifetime, there is a need to assess the knowledge and understanding of patients in relation to their disease process and its management.Methods: A cross sectional, observational, knowledge and attitude survey were carried on patients with type II diabetes mellitus who are taking insulin therapy and attended medicine diabetes OPD in tertiary care Hospital during the period of April 2017 to Dec 2017. 200 diabetic patients’ ≥18 years of age who were willing to respond to the study questionnaire were interviewed.Results: Total of 200 study participants were interviewed using structured questionnaires, almost 75 (37.5%) of the respondents were age group of 41 - 50 years. 109 (54.5 %) male, 67 (33.5%)Hindus, 121 (60.5 %) married,79 (39.5%) were primary school, 120 (73.8%) were family history of diabetes, duration of treatment1-3 years 72 (31.5 %), 160 (63%) of the study subjects know about diabetes is high blood glucose, 119(59.5%)of subjects know complications of diabetes, 165(82.5%) were know about insulin used for diabetes, 115 (57.5%) of patients know other substitute for insulin, 94 (47%) of the study subjects have knowledge of complications of insulin therapy, 85 (42.5) were know different types of insulin preparations, 141 (70.5%) were know insulin is mandatory in some patients,159 (79.5%) were understood the route of administration of insulin.Conclusions: The finding of present study showed that, diabetes patients had average knowledge and less favourable attitude among diabetic patients toward insulin therapy.

scholarly journals Treatment satisfaction among diabetics attending a tertiary care hospital of Rohtak, Haryana: a cross-sectional study

2019 ◽  
Vol 6 (4) ◽  
pp. 1623
Author(s):  
Meena Rajput ◽  
Yashodha Arivarasan ◽  
Rajesh Rajput ◽  
Aereosonova Khongsit
Keyword(s):  
Treatment Satisfaction ◽  
Tertiary Care ◽  
Drug Regimen ◽  
Cross Sectional Study ◽  
Positive Influence ◽  
Care Hospital ◽  
Oral Hypoglycaemic Agents ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Vernacular Language

Background: The epidemic of diabetes mellitus is rising globally due to urbanization, population growth, aging, obesity and sedentary life style. Treatment satisfaction is defined as the individual’s rating of important attributes of the process and outcomes of his/her treatment experience and it represents an important outcome as it is related to adherence and willingness to continue treatment.Methods: A cross-sectional descriptive hospital-based study was conducted at endocrinology OPD attached to Pt. B.D. Sharma PGIMS Rohtak, Haryana from May 2014 to April 2015. Five hundred diabetics (type 1 and 2) were recruited for the study. Patients registered on the day of interview were selected using systematic random sampling. A predesigned, pretested, semi-structured schedule which included socio-demographic variables of the study subjects along with information about family history of diabetes was filled by interviewing the study subjects in their vernacular language individually. DiabMedSat was used to assess the treatment satisfaction.Results: Nearly two third of the study participants were treated on oral hypoglycaemic agents (76.2%) followed by subjects treated on insulin+OHA (21.4%). 2.4% of the study subjects were on treatment with insulin alone. 87.8% of female subjects were satisfied with their treatment as compared to 86.3% of their male counterparts.Conclusions: Treatment satisfaction has a positive influence on quality of life of the study subjects as those who are satisfied tend to better adhere to their drug regimen thereby achieving a desirable glycaemic control and averting the complications associated with the disease thereby leading to a healthier life.

A 5 Years Audit Report on Diabetic Ketoacidosis Patients from a Tertiary Care Hospital in Saudi Arabia

2021 ◽  
Vol 15 (11) ◽  
pp. 3148-3152
Author(s):  
Asim Hassan ◽  
Mohammad Bilal Jaja ◽  
Mohammed Motasim Ali Haj Elamin
Keyword(s):  
Diabetes Mellitus ◽  
Saudi Arabia ◽  
Diabetic Ketoacidosis ◽  
Tertiary Care Hospital ◽  
Compliance Rate ◽  
Tertiary Care ◽  
Care Hospital ◽  
Presenting Symptoms ◽  
The Mean ◽  
Tract Infections

Objective: To evaluate the causes of high admission rate of diabetic ketoacidosis (DKA) in adults with diabetes mellitus presenting to a tertiary care hospital in Saudi Arabia with specific emphasis on the clinical and biochemical phenotype and identify components of intervention and improve clinical outcomes in these patients. Study Design: Observational study. Place and Duration of the Study: Department of Diabetes & Endocrinology, Armed Forces Hospital Al-Hada, Taif, Kingdom of Saudi Arabia from 1st August 2015 to 31st January 2020. Methodology: One hundred and fifteen patients with diabetes mellitus presenting with diabetic ketoacidosis during the last 5 years were enrolled. Approximately 50 different variables pertaining to the patients at the time of presentation were thoroughly scrutinized. Results: There were 31 (28%) males and 81 (72 %) were females with type 1 DM 92%, type 2 DM 7% and 1% unclassified DM with a mean age of 20.90±7.4 years. 18% were diagnosed to have DM for the first time and others had a mean duration of DM of 8.0±3.6 years with an average daily insulin requirement being 64.0±20.2 units. Moreover 84% of patients were on basal bolus regimen and only 5% were on mixed insulin. 73% of the DKA episodes occurred in 15-25 years of age group. The commonest precipitating factors were non-compliance with insulin (44%) and respiratory tract infections (17%). Most common presenting symptoms were vomiting and abdominal pain present in 81% and 53% of patients. The mean blood sugar on presentation was 463±157.3 mg/dl whereas the mean HbA1c was 14±2.9. The mean pH and bicarbonate levels on presentation were 7.16±0.128 and 7±4.83 meq/L respectively. 80% of the patients were admitted to the general wards however 19% required ICU care. 69% of patients had a history of readmission with DKA and 29% were transferred from another periphery hospital. The mean duration of stay in the hospital was 2±3.8 days and the mortality was 0.9%. Conclusion: A very low mortality rate is witness to excellent acute management of these very sick patients. However a very high non-compliance rate of 44%, combined with a readmission rate of 69% and a mean HbA1c of 14% are very alarming as far as long term prognosis is concerned. Keywords: Diabetes mellitus, Ketoacidosis, Characteristics, DKA, Tertiary level care

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