scholarly journals TYPE II DIABETICS

2016 ◽  
Vol 23 (02) ◽  
pp. 133-137
Author(s):  
Azfar Farogh ◽  
Muhammad Arif Mahmood ◽  
Khalil Ahmad
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Diabetic Ketoacidosis ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Type Ii ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Study Results ◽  
History Of

Objectives: To determine the frequency of diabetic ketoacidosis in type IIdiabetic patients. Study Design: Cross sectional study. Setting: Department of Medicine,Sahiwal Medical College Sahiwal. Period: September 2014 to March 2015. Material andmethod: Permission was taken from Institutional review board and written informed consentwas taken from every patient. Total 189 patients with type II DM (Un-controlled) having Fastingplasma glucose level ≥126mg/dl either male or female having age 35 years to 65 years wereincluded in the study. Results: Total 189 patients with type II diabetes mellitus were includedin this study. Mean age of the 50.09 ± 9.39 years. Male patients were 79 (42%) and femalepatients were 110 (58%). Insignificant association between gander and Ketoacidosis was seen.No association of family history of diabetes mellitus with Ketoacidosis was found. Conclusion:Results of this study showed that male or female can be equally victim of diabetic ketoacidosis.Diabetic ketoacidosis can be develop equally in younger or older age group. No significantdifference for the development of diabetic ketoacidosis was found between obese/non-obeseand patients with family history of diabetes or without family history of diabetes.

scholarly journals Prevalence and commonest predictors of gestational diabetes mellitus: a cross-sectional study

2019 ◽  
Vol 6 (1) ◽  
pp. 96
Author(s):  
Saranya Nagalingam ◽  
Vaishnavi Murugaraj
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Gestational Diabetes ◽  
Cross Sectional Study ◽  
Health Centers ◽  
Sectional Study ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Rural And Urban ◽  
History Of

Background: Babies born to mothers with GDM are at increased risk of complications, primarily growth abnormalities and chemical imbalances such as hypoglycemia, GDM is a reversible condition and women who have adequate control of glucose level scan effectively decrease the associated risks and give birth to healthy babies. The objective was to estimate the prevalence and the predictors of gestational diabetes mellitus.Methods: This study was conducted as a cross sectional study among the antenatal mothers at the outpatient department of the rural and urban health centers of the KG hospital and PG institute and its affiliated centers in Coimbatore. The study period was one year and during which 150 antenatal mothers participated in the study.Results: The prevalence of GDM was 76 (9%) and 74 (11%) in rural and urban health centers respectively. The maximum number of GDM Mothers to be 26-30years of age with a peak indicating 42% and 39% of GDM mothers were found to be in primigravida, 48% of GDM mothers were primipara. About 65% of GDM pre-pregnant mothers were overweight according to BMI, 53% of GDM mothers had positive family history of DM. Majority of the study population 100 (67%) had HBA1C less than 6% and the remaining 50 (33%) had more than 6% value. The variables like age, gravida, parity, family history of diabetes, pre-pregnant BMI, history of PCOS, history of hypertension, history of hypothyroidism was compared with the glycaemic status (HBA1C values) and it was found to be statistically significant at P<0.05.Conclusions: The commonest risk factors which increases the incidence of GDM were family history of diabetes mellitus, overweight pre-pregnant BMI, history of PCOS, hypothyroidism, increasing gravidity and parity respectively.

Evaluation of Frequency of Diabetic Ketoacidosis and Presenting Symptoms in Patients of Diabetes Mellitus Presenting

2021 ◽  
Vol 15 (12) ◽  
pp. 3390-3392
Author(s):  
Shahnaz Noor ◽  
Irum Noor ◽  
Sadia Bashir
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Tertiary Care ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Serum Glucose ◽  
Care Hospital ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Presenting Symptoms

Objective: To evaluate the frequency of diabetic ketoacidosis and presenting symptoms in patients of diabetes mellitus presenting at tertiary care hospital. Material and methods: In this cross sectional study total 145 patients of diabetes were selected from Department of Medicine from April 2020 to November 2020. Inclusion criteria was: un-controlled type II Diabetes Mellitus with HBA1c levels > 8, age between 30-70 years, male or female. Diabetic ketoacidosis was studied in selected patients. Results: Mean age of the patients 49.80 ± 9.38 years. Out of 145 patients, ketoacidosis was found in 30 (21%) patients. Vomiting was the most common (88/60.69%) presenting symptom followed nausea in 59 (40.68%) patients, polyuria 50 (34.48%), polydipsia 41 (28.27%), abdominal pain 32 (22.07%), weight loss 16 (11.03%) and Polyphagia in 8 (5.52%) patients. Ketoacidosis was found in 15 (23.44%) male diabetics and 15 (18.52%) female diabetics. Association of ketoacidosis with gender was not significant (P = 0.468). Conclusion: Findings of this study showed a higher rate of diabetic ketoacidosis. Vomiting was the most common presenting symptom. Most of the patients were between 30-50 years. No gender difference was found in development of diabetic ketoacidosis. Most of the patients of diabetic ketoacidosis had family history of diabetes. Keywords: Ketone, Ketoacidosis, fasting serum glucose, diabetes mellitus, random serum glucose

scholarly journals Risk factors for type 2 diabetes mellitus: An urban perspective

2019 ◽  
Vol 71 ◽  
pp. 16-21
Author(s):  
Reshma Patil ◽  
Jayashree Gothankar
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Family History ◽  
Waist Circumference ◽  
Cross Sectional Study ◽  
Lifestyle Changes ◽  
Chi Square ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
History Of

Background: Diabetes mellitus is rising to an alarming epidemic level; hence, strategies formulated based on the risk factors can be helpful to curb the rising trend of the same. Objective: The objective of the study was to assess the prevalence of diagnosed cases of diabetes mellitus and correlate it with various risk factors and sociodemographic variables. Methods: A cross-sectional study was carried out in randomly selected wards under the field practice area of Urban Health Training Center of Private Medical College, Pune, Maharashtra. A total of 425 subjects aged 20 years and above residing in the study area were screened for diabetes mellitus. Risk factors such as age, waist circumference, waist-to-hip ratio (WHR), family history of diabetes, and physical activities were recorded. The statistical analysis of the data was performed using Chi-square test. Results: The prevalence of diagnosed cases of diabetes mellitus found in this study was 9.88%. There was a significant increase in the prevalence of diabetes as age increases (age 20–34 years: 1.66%, 35–49 years: 7.53%, ≥50 years: 15.66%, and P < 0.05). Furthermore, male gender, obesity, waist circumference, WHR, and diabetes mellitus were found to be statistically significant. Conclusions: Risk factors such as rising age, family history of diabetes mellitus, lack of physical activity, and central obesity were the most common factors found in diagnosed cases of diabetes mellitus. Therefore, lifestyle changes and awareness regarding risk factors is needed to make control over the diabetes.

scholarly journals Evaluation of Dyslipidaemia Using an Algorithm of Lipid Profile Measures among Newly Diagnosed Type II Diabetes Mellitus Patients: A Cross-Sectional Study at Dormaa Presbyterian Hospital, Ghana

Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 392
Author(s):  
Enoch Odame Anto ◽  
Christian Obirikorang ◽  
Max Efui Annani-Akollor ◽  
Eric Adua ◽  
Sampson Donkor ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Presbyterian Hospital ◽  
History Of

Background and Objectives: Dyslipidaemia and its associated complications have been reported to increase mortality among type 2 diabetes mellitus (T2DM) patients. However, there is a dearth of data on the incidence of dyslipidemia among Ghanaian patients with T2DM. This study evaluated dyslipidemia among newly diagnosed T2DM patients at Dormaa Presbyterian Hospital, Ghana. Materials and Methods: This cross-sectional study recruited a total of 215 participants at the Presbyterian Hospital, Dormaa-Ghana. A well-structured questionnaire was administered to collect demographic data. Predisposing factors of dyslipidemia such as BMI, hypertension, and family history of diabetes were also obtained. Lipid profile was performed on the serum obtained from each respondent. Dyslipidaemia was defined as total cholesterol (TC) >200 mg/dL, triglyceride (TG) >150 mg/dL, low density lipoprotein cholesterol (LDL-c) >100 mg/dL, and high-density lipoprotein cholesterol (HDL-c) <40 in males and <50 mg/dL in females. Combinations of the individual parameters of dyslipidaemia were further evaluated. Results: Of the total (215) participants, 86 (40%) were males and 129 (60%) were females, representing a ratio of 1:1.5. High total cholesterol was more prevalent in females (69.0%) than males (53.5%). Generally, dyslipidaemia was predominant among those aged >40 years, with the exception of increased LDL-c (25.1%), which was higher among the 20–40 years age group. The male participants exhibited significantly (p < 0.001) higher percentages of all combined measures of dyslipidaemia—such as high TG and reduced HDL-c (77.9%), high TG and elevated LDL-c (75.6%) and high LDL and low HDL (65.1%). BMI was significantly associated with HDL levels (p = 0.02), whereas family history of diabetes was associated with TC (p = 0.004) and TG levels (p = 0.019). Conclusion: Combined dyslipidaemia is relatively high among newly diagnosed T2DM patients in Ghana, and in those >40 years. Gender is significantly associated with combined dyslipidaemia in T2DM, and males may be at a higher risk than females. BMI and family history of diabetes are potential risk factors of dyslipidaemia in T2DM.

scholarly journals Differential expression of micro RNA-29 family in non-diabetic adults of diabetic and non-diabetic parents

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Uzair Abbas ◽  
Bushra Imdad ◽  
Sikander Adil Mughal ◽  
Israr Ahmed Baloch ◽  
Afshan Mehboob Khan ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Family History ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Vital Role ◽  
Micro Rna ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
History Of

Abstract Objective MicroRNAs are known to regulate 60% of genes at post translational level. MicroRNAs including Micro RNA-29 family play a vital role in cellular activities and have validate role in numerous metabolic disorders inclusive of diabetes mellitus and its complications. While micro RNA profile changes years before the occurrence of disease. This cross-sectional study was conducted in non-diabetic adults of diabetic and non-diabetic parents to explore the early changes in expression of micro RNA-29 family as it can be served as early biomarker of type 2 diabetes in non-diabetic adults. This study was conducted from January 2019 to January 2021. Micro RNA was extracted from plasma of 50 participants and expression was compared through qPCR. While data was analyzed through SPSS version 21.0. Results 29a and 29b had lower expression in participants with family history of DM compared to those having no family history of DM (P < 0.0001). While micro RNA 29c was found to be significantly higher in participants with positive family history of type 2 diabetes as compared to those without family history of diabetes (P = 0.001).

scholarly journals THE DEMOGRAPHIC PROFILE OF WOMEN WITH GESTATIONAL DIABETES MELLITUS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Priyanka Inaniya ◽  
B S Meena ◽  
Mohan Lal Meena ◽  
Aparna Sharma ◽  
Shalini Rathore
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Demographic Profile ◽  
Medical College ◽  
History Of ◽  
Socio Demographic Factors

Background: The present study aimed to study the demographic profile women with gestational diabetes mellitus Methods: This hospital based cross-sectional study Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur. Results: Mean age of patients was 27.68 ± 4.4 Yrs. Most of the study subjects in GDM group (54.7%) were Hindu. Study subjects in GDM group were almost equally from rural (50.7%).Most of the study subjects in both GDM group (88%) were housewives. Habit of smoking was found in only 6.7% females in GDM group. Habit of alcohol was found in 4% females in GDM group. Family history of diabetes was seen more in females with GDM (17.3%). Conclusion: This study concluded that the socio demographic factors influence the occurrence of GDM. Keywords: GDM, Age, Gravida

scholarly journals The prevalence of insulin resistance in patients with β -thalassemia major at Cipto Mangunkusumo Hospital

2016 ◽  
Vol 43 (4) ◽  
pp. 117
Author(s):  
Caroline Mulawi ◽  
Bambang Tridjaja ◽  
Maria Abdulsalam ◽  
Zakiudin Munasir
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Family History ◽  
Glucose Metabolism ◽  
Thalassemia Major ◽  
Oral Glucose ◽  
Model Assessment ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
History Of

Background Diabetes mellitus is a common complication in pa-tients with thalassemia major. Iron overload plays an important roleby damaging the pancreatic β-cell and the liver cell, with the con-sequences of insulin deficiency and insulin resistance. Family his-tory of diabetes mellitus is one of the critical factors for the devel-opment of glucose metabolism derangement. However, the patho-genesis of glucose metabolism derangement remains unclear.Objective To evaluate the prevalence of impaired glucose toler-ance, diabetes mellitus, and insulin resistance in patients with β-thalassemia major treated in the Thalassemia Outpatient Clinic,Department of Child Health, Cipto Mangunkusumo Hospital,Jakarta.Methods This was a descriptive cross sectional study conductedin May 2002. Forty-eight subjects aged 10 to 18 years, grouped bytotal volume of transfusions and family history of diabetes mellitus,underwent an oral glucose tolerance test (OGTT), serum transfer-rin saturation, and insulin level examinations. Insulin resistancewas calculated from fasting plasma glucose and insulin concen-trations using the homeostasis model assessment (HOMA).Results One of 48 patients (2%) had impaired glucose toleranceat the age of 17 years. Diabetes mellitus occurred in three of 48patients (6%) at the age of 15.5 years in one patient and 18 yearsin two patients. Family history of diabetes mellitus was found in 2patients with diabetes mellitus and in the only one with impairedglucose tolerance. Insulin resistance was not detected in this study.Conclusion The prevalence of glucose metabolism derangementin patients with thalassemia major was low. No insulin resistancewas found in this study

FAMILY HISTORY OF DIABETES IS ASSOCIATED WITH INCREASED RISK OF RECURRENT DIABETIC KETOACIDOSIS IN PEDIATRIC PATIENTS

2020 ◽  
Vol 26 (3) ◽  
pp. 305-311
Author(s):  
Janaki D. Vakharia ◽  
Sungeeta Agrawal ◽  
Janine Molino ◽  
Lisa Swartz Topor
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Diabetic Ketoacidosis ◽  
Pediatric Patients ◽  
Incidence Rate Ratio ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
History Of

Objective: To determine the relationship between family history of diabetes mellitus (DM) and diabetic ketoacidosis (DKA) recurrence in youth with established type 1 diabetes mellitus (T1DM). Methods: We performed a retrospective chart review of patients with DKA admitted to a pediatric hospital between January, 2009, and December, 2014. We compared patients with recurrent (≥2 admissions) and nonrecurrent DKA (1 admission) and investigated patient level factors, including family history, that may be associated with DKA recurrence in pediatric patients with established T1DM. Results: Of the 131 subjects in the study, 51 (39%) subjects were in the recurrence group. Age ≥15 years old, public health insurance, and family history of T1DM or type 2 diabetes mellitus were associated with recurrent DKA admissions in both univariable and multivariable analyses. Family history was associated with DKA recurrence, with an incidence rate ratio of 1.5 (95% confidence interval = 1.0 to 2.3; P = .03). The association was not explained by type of familial diabetes, first degree relative status, or whether the family member lived in the household. Conclusion: Recognition that a positive family history of DM may be associated with a higher risk for DKA recurrence in patients with established T1DM may allow for targeted education and focus on a previously unidentified population at increased risk for DKA. Understanding the mechanism underlying the effect of family history of diabetes on the rates of DKA in patients with established T1DM may allow for improved identification and education of patients who may be at risk for DKA recurrence. Abbreviations: CI = confidence interval; DKA = diabetic ketoacidosis; EHR = electronic health record; IBD = inflammatory bowel disease; IRR = incidence rate ratio; T1DM = type 1 diabetes mellitus; T2DM = type 2 diabetes mellitus

scholarly journals Sweet Taste Threshold among Medical Students with Family History of Diabetes Mellitus

2020 ◽  
Vol 7 (4) ◽  
Author(s):  
Nasya Aisah Latif ◽  
Yulia Sofiatin ◽  
Maya Kusumawati ◽  
Rully Marsis Amirullah Roesli
Keyword(s):  
Diabetes Mellitus ◽  
Medical Students ◽  
Family History ◽  
Sweet Taste ◽  
Diabetic Patients ◽  
Taste Threshold ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
History Of

Background: Diabetic patients have low sensitivity towards sweet taste, thus consuming more sugar. A young adult with family history of diabetes mellitus (FHD) who lives with diabetic parents may have an increased risk of overconsumption of sugar due to a similar dietary pattern, leading to diabetes. This study aimed to explore the difference in the sweet taste threshold (STT) between students with and without a family history of diabetes mellitus. Methods: This cross-sectional study was conducted in October –November 2018 on Class 2018 medical students living in a student dormitory who were divided into those with family history of diabetes (FHD) and those without it (non-FHD). Family history of diabetes and other known diseases were self-reported. The three-Ascending Forced Choice method was used to determine the sweet recognition threshold. Mann-Whitney analysis was used to compare the sweet taste thresholds between the two groups. Result: A total of 183 subjects participated in this study. The non-FHD group had a higher rank of sweet taste threshold than subjects in the FHD group (94.21 vs 81.16), albeit insignificant (p=0.192). Interestingly, the modes of best estimation threshold (BET) for non-FHD group was than the FHD group (0.067 M vs 0.043 M). Conclusion: The BET for students without family history of diabetes is higher than those with family history of diabetes. It is imperative that low sugar consumption campaign should also aim young people without FHD.

Sign in / Sign up

Export Citation Format

Share Document