Association between Skin Type and Idiopathic Hirsutism: A Case Control Study

2021 ◽  
Vol 15 (12) ◽  
pp. 3424-3426
Author(s):  
Aashi ahmed ◽  
Aqsa Naheed ◽  
Zahra Babar ◽  
Javeria Hafeez ◽  
Tehseen Naveed ◽  
...  
Keyword(s):  
Case Control Study ◽  
Rating Scale ◽  
Medical Condition ◽  
Well Being ◽  
Case Control ◽  
Skin Type ◽  
Type Iii ◽  
Idiopathic Hirsutism ◽  
Ovarian Syndrome ◽  
Control Study

Background: Hirsutism is a medical condition characterized by presence of excessive terminal (coarse) hair among females in androgen-dependent areas. psychological well-being of females is negatively influenced by hirsutism. Poly cystic ovarian syndrome (PCOS) is the most common cause of hirsutism. However, hirsutism is found to exist without any underlying cause and is known as idiopathic hirsutism (IH). Studies have shown correlation between skin type and hirsutism among PCOS cohorts; however, no such relationship is known to exist between skin type and idiopathic hirsutism. Objective: To determine association between skin type and idiopathic hirsutism. Study Design: Case control study Place and Duration of Study: Department of Dermatology, HIT Hospital Taxila from 1st March 2019 to 29th February 2020. Methodology: 118 cases and 133 controls were included in study after informed consent. Skin type was determined by Fitzpatrick skin type (FST) rating scale ranging from I to IV. Modified Ferriman-Gallwey (mFG) visual four-point scale was used to quantify hirsutism into mild, moderate and severe. Results: Mean age of cases and controls was 31.01±9.5 years and 28.01±9.7 years respectively. Seventy four (62.7%) of cases and 88 (66.2%) controls had type III skin type. Eighty (67.8%) had mild (8-15) hirsutism. Statistically insignificant (P<0.05) association was found to exist between skin type and idiopathic hirsutism and severity of hirsutism. However, a statistically significant {P<0.05) association existed between hirsutism and BMI. Conclusion: Idiopathic hirsutism is found to have no association with skin type III or IV among Caucasians. However, this finding needs further investigation involving diverse population including representation from all skin types (I and II) Key Words: Idiopathic hirsutism, Skin types, PCOS, Hyperandrogenemia

scholarly journals Mental and personality disorders in infertile women with polycystic ovary: a case-control study

2020 ◽  
Vol 20 (3) ◽  
pp. 1241-1249
Author(s):  
Mostafa Ahmadi ◽  
Mahbobeh Faramarzi ◽  
Zahra Basirat ◽  
Farzan Kheirkhah ◽  
Mohammad Chehrazi ◽  
...  
Keyword(s):  
Personality Disorders ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Infertile Women ◽  
The Mean ◽  
Ovarian Syndrome ◽  
Control Study

Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common causes of infertility in women. Objective: The current study investigated mental and personality disorders in infertile women with and without PCOS. Methods: This case-control study evaluated 400 infertile women who referred to the Infertility Center in Babol city (North of Iran). Participants were categorized into the case group (201 PCOS) and the control group (199 without PCOS). All of the participants completed the Millon Clinical Multi-axial Inventory-III (MCMI-III). Results: The mean scores for clinical personality patterns were significantly higher for six personality disorders (schiz- oid, avoidant, antisocial, depressive, sadistic, and negativistic) and for three classes of severe personality disorder patterns (schizotypal, borderline, and paranoid) in infertile women with PCOS than in women without PCOS. The mean scores for eight clinical disorders (somatoform, manic disorder, dysthymia, alcohol-dependence, drug-dependence, post-trauma stress disorder, major depression, and delusion disorder) were also higher in infertile women with PCOS than in women without PCOS. Conclusion: The scores of many mental and personality disorders are higher in infertile women with PCOS than in women without PCOS. Thus, clinicians should prioritize recognizing and treating psychological problems of infertile women with PCOS. Keywords: Polycystic ovarian syndrome; infertility; personality disorders.

scholarly journals Clinical and Genetic Factors Associated with Resistance to Treatment in Patients with Schizophrenia: A Case-Control Study

2019 ◽  
Vol 20 (19) ◽  
pp. 4753 ◽  
Author(s):  
Aline Hajj ◽  
Sahar Obeid ◽  
Saria Sahyoun ◽  
Chadia Haddad ◽  
Jocelyne Azar ◽  
...  
Keyword(s):  
Genetic Factors ◽  
Case Control Study ◽  
Rating Scale ◽  
Multivariable Analysis ◽  
Case Control ◽  
Response To Treatment ◽  
Treatment Resistant ◽  
Factors Associated ◽  
Resistance To Treatment ◽  
Control Study

Objectives: To assess clinical and genetic factors affecting response to treatment in a sample of patients with schizophrenia (treatment-resistant patients versus treatment responders). We also aimed at examining if these factors are different when we consider two different resistance classifications (the positive and negative syndrome scale, PANSS and the brief psychiatric rating scale, BPRS). Material and Methods: A case-control study included treatment-resistant patients and good responders. Patients were stratified in two groups based on the established criteria for treatment-resistant schizophrenia using BPRS and PANSS. The study was approved by the ethical committees (references: CEHDF1017; HPC-017-2017) and all patients/legal representatives gave their written consent. Clinical factors were assessed. DNA was obtained using a buccal swab and genotyping for OPRM1, COMT, DRD2 et MTHFR genes using the Lightcycler® (Roche). Results: Some discrepancies between the BPRS and PANSS definitions were noted in our study when assessing the patients’ psychopathological symptoms and response to treatment. The multivariable analysis, taking the presence versus absence of treatment resistance as the dependent variable, showed that that family history of schizophrenia, university studies, time since the beginning of treatment and chlorpromazine equivalent dose as well as the COMT gene are associated with resistance to treatment. In addition, a gender-related difference was noted for COMT SNP; men with at least one Met allele were more prone to be resistant to treatment than Val/Val patients. Conclusion: Uncovering the clinical and genetic factors associated with resistance to treatment could help us better treat our schizophrenic patients in a concept of personalized medicine.

scholarly journals Risk factors for attention-deficit/hyperactivity disorder: a case-control study in 5 to 12 years old children

2020 ◽  
Author(s):  
Fahimeh Soheilipour ◽  
Sareh Shiri ◽  
Hamid Reza Ahmadkhaniha ◽  
Ebrahim Abdollahi ◽  
Fatemeh Sadat Hosseini-Baharanchi
Keyword(s):  
Risk Factors ◽  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Case Control Study ◽  
Rating Scale ◽  
Neurodevelopmental Disorder ◽  
Case Control ◽  
Neonatal Disease ◽  
Hyperactivity Disorder ◽  
Control Study

Background and aims. Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder known by a pattern of diminished sustained attention and increased impulsivity or hyperactivity. This study aimed to evaluate the risk factors associated with ADHD. Methods. This case-control study included 297 ADHD children aged 5-12 years admitted to Tehran Institute of Psychiatry, Iran (2012-2013). They were compared with 297 non-ADHD (as controls matched to cases 1:1) who were of the same age (±1 years) selected from outpatients in general pediatric medical centers in Tehran. ADHD Rating Scale IV (ADHD-RS-IV)-Home Version was used to confirm ADHD. Data were analyzed using conditional binary logistic regression. Results. Mean±SD age were 8.18±3.11 and 8.11±2.9 years in the case and control groups, respectively (P=0.61). Mean±SD birth weight (BW) was higher in ADHD patients compared with the controls (3245.09±0.66 vs 3026.56±0.45 gr, P=0.045). The results showed that odds of ADHD in children with high BW (>3500g) was 3.36 (1.96-5.78) times the odds of ADHD in normal BW children (2500-3500g) controlling for other risk factors. ADHD risk in low BW children (<2500 g) was not statistically different compared with normal BW children [OR:1.74 (0.7-3.7)]. Experience of neonatal disease, fewer offspring, lower level of mothers’ education, and preterm delivery were also risk factors for higher odds of ADHD. Conclusion. Based on our sample, preterm birth, neonatal disease, high BW, lower level of mother's education, and fewer offspring were ADHD risk factors.

scholarly journals Effect of body weight on serum homocysteine level in patients with polycystic ovarian syndrome: A case control study

2016 ◽  
Vol 14 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Ali Al- Gareeb ◽  
Wafaa Salah Abd Al- Amieer ◽  
Hayder M. Alkuraishy ◽  
Thabat J. Al- Mayahi ◽  
◽  
...  
Keyword(s):  
Body Weight ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Homocysteine Level ◽  
Case Control ◽  
Serum Homocysteine ◽  
Ovarian Syndrome ◽  
Control Study
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