scholarly journals Ethnopharmacological survey of six medicinal plants used in the traditional treatment of urinary tract infections and other infectious diseases

2021 ◽  
Author(s):  
Phénix Assogba ◽  
Eric Agbodjento ◽  
Remi Akotegnon ◽  
Victorien Dougnon ◽  
Jean Robert Klotoe

Benin has attractive ethnobotanical potential with a vast diversity of medicinal plants widely used to treat human diseases. Urinary tract infections are among the diseases traditionally treated by medicinal plants. Mangifera indica, Bridelia ferruginea, Alstonia boonei, Morodora myristica, Xylopia aethiopica and Zanthoxylum zantoxyloides are six plants used in the traditional treatment of urinary infections in Benin. The general objective of this study was to identify the ethnopharmacological uses of these six plants used in traditional medicine in South Benin. To this end, an ethnopharmacological survey was conducted using the semi-structured interview method among herbalists in the markets of South Benin. The ethnobotanical data collected were analyzed using the use-value, the informant consensus factor and the medicinal plant fidelity index. A total of 98 herbalists participated in this study. The six plants studied were involved in 15 different diseases divided into seven disease categories. The most mentioned disease categories are infectious diseases, blood and digestive diseases. Malaria, ulcers, anemia and urinary tract infections are the pathologies most commonly treated by these plants. Informants agreed on the use of these plants in these disease categories. Bark, leafy stems and roots are the parts of the plants most used to treat diseases. Decoction and maceration are the two main methods of preparation, and the oral and cutaneous routes are the main routes of administration. These data constitute ethnopharmacological documentation that can be used for further pharmacological and toxicological studies.

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Phénix Assogba ◽  
Victorien Dougnon ◽  
Edna Hounsa ◽  
Pierre Badjabaissi ◽  
Rachida Moussa Tari ◽  
...  

Objective. Mangifera indica Linn, Bridelia ferruginea Benth, and Alstonia boonei De Wild are three plants commonly used in the traditional treatment of urinary tract infections in Benin. This study sets out to assess the cytotoxic and teratogenic effects of extracts of these plants on Artemia salina larvae and hen embryos. Methods and Results. The aqueous and ethanolic extracts were obtained by maceration of the powders in solvents. Larval cytotoxicity was performed on Artemia salina larvae. The teratogenic effect of these plants was evaluated on chick embryos at 100 mg/kg and 300 mg/kg. The extracts were injected on the 7th and 14th days of incubation. The quality of the hatched chicks was evaluated by the Tona score followed by the hematological and the biochemical parameter assays. The extracts did not show cytotoxicity on the larvae. The eggs treated with plant extracts at 300 mg/kg significantly lowered the hatchability rate, except for the Mangifera indica Linn. The chicks obtained were all at the very good quality. Then, no significant variation was observed between hematological parameters except white blood cells. For the biochemical parameters, only ASAT showed some significant variations for a few extracts. It would be important to assess the genotoxicity of the plant extracts to determine more broader toxicity. These data justify the use of these medicinal plants in traditional Beninese medicine and constitute in fact a source of production of anti-infectious drugs.


2019 ◽  
Vol 21 (96) ◽  
pp. 33-40
Author(s):  
M. T. Tion ◽  
G. A. Zon ◽  
H. A. Fotina ◽  
K. I. Ogbu ◽  
S. A. Nguetyo ◽  
...  

An epizootiology of infectious diseases/conditions of dog in some veterinary clinics from Benue, Plateau states and the Federal Capital Territory in Nigeria were assessed from 2015 to 2018. This study revealed about seventeen (17) infectious clinical cases/conditions from 1865 cases recorded within the period of four (4) years. These comprised of helminthoses (17.8%) having the highest prevalence followed by babesiosis (17.5%), parvovirosis (15.9%), ectoparasitism (11.3%), scepticemia (6.9%), Mange (5.7%), urinary tract infections (4.7%), canine distemper (4.2%), colitis (3.9%), myiasis (2.7%), trypanosomosis (2.1%), leptospirosis and transmissible venereal tumor (1.9%), respiratory infections (1.7%), otitis (1.0%) and orchitis (0.7%). Puppies (0–6 months old) 50.2% were mostly affected. Incidences of diseases were more in Alsatians (23.7%), Cross (22.9%), Nigerian indigenous breed (20.5%), Caucasian (9.6%) and Rottweiler (8.9%). More cases of vaccinated (68.7%) were recorded against the unvaccinated (31.3%) dogs while male (57.1%) dogs had a higher frequency of cases as compared with their female (42.9%) counterpart. Disease incidence was highest in dry season (54.3%) especially in the months of December (13.3%), January (11.1%) and February (10.6%).The highest frequency of disease incidence was recorded in 2015 (36.4%). Most the infectious clinical cases/conditions recorded from this study were preventable cases demanding veterinary care in order to prevent the risk of zoonosis.


2017 ◽  
Vol 23 (4) ◽  
pp. 175-179
Author(s):  
Anca Daniela Pînzaru ◽  
Raluca Mihai ◽  
Octavia Burcea ◽  
Simona Claudia Cambrea

AbstractIntroduction: In pediatrics, the urinary tract infection is one of the most frequent bacterial infection, representing an important health problem due to its high incidence, wide etiology, asymptomatic evolution, and multiple and sever complications, relapses and sequelae.” Material and Method: We evaluated 45 children, aged between 6 months and 16 years, diagnosed and treated for urinary tract infection at the Clinical Infectious Diseases Hospital, of Constanta County, in a period of 3 years and 6 months. Results: During studied period, between January 2014 and June 2017 from a total of 9343 patients admitted to the Constanta Clinical Infectious Diseases Hospital, we selected 45 children (4.81‰) diagnosed with urinary tract infection. The average age of children with urinary tract infections was 5 years and 5 months. The gender distribution revealed a 2:1 balance in girl’s favor. The most affected group of age was 1-3 years. Fever was the dominating symptom. Urine cultures were positive for 37 cases, meanwhile for eight cases had been negative. The predominant germs are E. coli for female and for male Proteus. We noticed that for E. coli the highest sensitivity is preserved to Ertapenem -15 cases, followed by Ceftriaxone and Ciprofloxacin -10 cases each, and Gentamycin -9 cases. Conclusions: Pediatric urinary tract infection should be considered in every patient under 3 years with unexplained fever.


Author(s):  
Imad Hadi Hameed ◽  
Abeer Fauzi Al-Rubaye ◽  
Mohanad Jawad Kadhim

Medicinal plants are part and parcel of human society to combat diseases from the dawn of civilization. According to World Health Organization (WHO), about 80% of the world population rely chiefly on plant based traditional medicine specially for their primary health care needs and there has been a worldwide move towards the use of traditional medicines due to concerns over the more invasive, expensive and potentially toxic main stream practices. This review gives a bird’s eye view on the updated information on urinary tract infections (UTIs), different categories of urologic herbs, historical use and modern scientific investigations on some important urologic herbs, clinical studies, some isolated chemical compounds and their possible side effects


2015 ◽  
Vol 64 (6) ◽  
pp. 91-104 ◽  
Author(s):  
Elena Vasilyevna Shipitsyna ◽  
Tatyana Alekseyevna Khusnutdinova ◽  
Alevtina Mikhailovna Savicheva ◽  
Tatyana Aykovna Ayvazyan

Urinary tract infections (UTIs) are among the most common infectious diseases in women, and are the most frequent cause of infectious complications of pregnancy. This paper reviews current scientific and methodical literature on UTIs in obstetrics and gynecology. Aspects of clinical importance of UTIs (epidemiology, clinical manifestations, complications), their etiology, antimicrobial resistance of UTIs agents were discussed, and current recommendations on diagnostics and treatment of UTIs were summarized. Special attention was paid to UTIs in pregnancy.


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