Protective effects of radix salviae miltiorrhizae and radix scutellariae on liver disease : an biomedical investigation integrated with in silico method

2017 ◽  
Author(s):  
Ming Hong
Keyword(s):  
Liver Disease ◽  
In Silico ◽  
Protective Effects ◽  
Radix Salviae Miltiorrhizae ◽  
Salviae Miltiorrhizae ◽  
Radix Scutellariae ◽  
Biomedical Investigation

Protective effects of fucoidan against ethanol-induced liver injury through maintaining mitochondria function and mitophagy balance in rats.

2021 ◽  
Author(s):  
Huichao Zhao ◽  
Shuang Liu ◽  
Hui Zhao ◽  
Meilan Xue ◽  
Huaqi Zhang ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Injury ◽  
Alcoholic Liver Disease ◽  
Therapeutic Strategy ◽  
Hepatic Lesion ◽  
Protective Effects ◽  
Regulatory Effects

For alcoholic liver disease (ALD), mitophagy was reported as a promising therapeutic strategy to alleviate the hepatic lesion elicited by ethanol. This study was to investigate the regulatory effects of...

Improved stability of salvianolic acid B from Radix Salviae miltiorrhizae in deep eutectic solvents

2016 ◽  
Vol 8 (11) ◽  
pp. 2502-2509 ◽  
Author(s):  
Jue Chen ◽  
Shi-fei Li ◽  
Zhi-feng Yao ◽  
Da-wei Yang ◽  
Li-wei Zhang
Keyword(s):  
Environmentally Friendly ◽  
Deep Eutectic Solvents ◽  
Salvianolic Acid B ◽  
Radix Salviae Miltiorrhizae ◽  
Salvianolic Acid ◽  
Salviae Miltiorrhizae ◽  
Improved Stability ◽  
The Stability

Environmentally friendly deep eutectic solvents were developed for enhancing the stability of salvianolic acid B from Radix Salviae miltiorrhizae.

scholarly journals Simultaneous Determination and Pharmacokinetic Comparisons of Multi-Ingredients after Oral Administration ofRadix Salviae MiltiorrhizaeExtract, Hawthorn Extract, and a Combination of Both Extracts to Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Yu-Qiang Liu ◽  
Qian Cai ◽  
Chang Liu ◽  
Feng-Wei Bao ◽  
Zhen-Qiu Zhang
Keyword(s):  
Oral Administration ◽  
Simultaneous Determination ◽  
Pharmacokinetic Study ◽  
Rosmarinic Acid ◽  
Rat Plasma ◽  
Hplc Method ◽  
Radix Salviae Miltiorrhizae ◽  
Salviae Miltiorrhizae ◽  
Hawthorn Extract

A simple and sensitive HPLC method was developed for simultaneous determination of danshensu (DSS), rosmarinic acid (RA), lithospermic acid (LA), salvianolic acid B (SAB), and hyperoside (HP) in rat plasma. This method validated was successfully applied to the pharmacokinetic study of the main active ingredients after oral administration ofRadix Salviae Miltiorrhizaeextract (SME), hawthorn extract (HTE), and a combination of both extracts (2.5 : 1) to rats. The results indicated that there have been great differences in pharmacokinetics between a single extract and a combination of both extracts. A combination of both extracts can enhance their bioavailabilities and delay the elimination of SAB and DSS in rats.

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