scholarly journals RESÍDUOS DE 14C-PROCHLORAZ EM MANGAS IRRADIADAS

2001 ◽  
Vol 11 ◽  
Author(s):  
MARIA APARECIDA COSTA ◽  
VALDEMAR LUIZ TORNISIELO ◽  
JULIO MARCOS MELGES WALDER
Keyword(s):  
Gamma Radiation ◽  
Degradation Product ◽  
Radiation Treatment ◽  
Refrigerated Storage ◽  
Post Harvest ◽  
Brazilian Legislation ◽  
Low Levels

O objetivo deste trabalho foi avaliar os níveis residuais de Prochloraz aplicado em mangas, na pré e pós-colheita após o tratamento com radiação. Os frutos foram submetidos à radiação gama na dose de 1,0 kGy visando verificar se a mesma induziu a degradação do fungicida. As mangas tratadas na pós-colheita foram armazenadas por 21 dias a 12 °C. Os resíduos de Prochloraz não apresentaram decréscimo durante o período de carência (21 dias) estabelecido pela Legislação Brasileira de Agrotóxicos. O armazenamento refrigerado (12 °C) e a irradiação gama também não contribuíram para a degradação do fungicida. O Prochloraz ficou retido principalmente na casca (média = 1,64 µg/g), que funcionou como barreira à contaminação da polpa (média = 0,06 µg/g). O produto de degradação, formado nas cascas das mangas tratadas na pós-colheita, foi identificado como sendo o BTS 44596. Os metabólitos, encontrados em níveis baixos, confirmaram a ocorrência de baixa degradação do fungicida em mangas. 14C-PROCHLORAZ RESIDUES IN IRRADIATED MANGOES Abstract The aim of this work was to evaluate the Prochloraz residual levels applied in mangoes, in pre and post-harvest after radiation treatment. The fruits were submitted to gamma radiation with of 1,0 kGy dose, aiming to verify if it induces the fungicide degradation. Treated post-harvest mangoes were stored, at 12 0C during 21 days. Prochloraz residues did not present reduction after safe period (21 days), established by the Brazilian legislation on agrochemicals. The refrigerated storage (12 0C) and the gamma radiation also did not contribute to the degradation of the fungicide. Prochloraz was mainly retained in the peels (mean = 1,64 µg/g) which served as barrier to the pulp (mean = 0,06 µg/g) contamination. The degradation product, formed in peels of post-harvest treated mangoes was the metabolite BTS 44596. The metabolites found in very low levels, confirm that low fungicide degradation occurs in mangoes.

scholarly journals Gamma radiation treatment activates glucomoringin synthesis in Moringa oleifera

2017 ◽  
Vol 27 (5) ◽  
pp. 569-575 ◽  
Author(s):  
Tsifhiwa Ramabulana ◽  
Risimati D. Mavunda ◽  
Paul A. Steenkamp ◽  
Lizelle A. Piater ◽  
Ian A. Dubery ◽  
...  
Keyword(s):  
Gamma Radiation ◽  
Moringa Oleifera ◽  
Radiation Treatment

Effect of Gamma Radiation on Dyeing of Cotton Fabric with Reactive Blue 13

2011 ◽  
Vol 15 (3) ◽  
pp. 107-114 ◽  
Author(s):  
Iram Batool ◽  
Ijaz Ahmad Bhatti ◽  
Shahid Adeel ◽  
Muhammad Abbas
Keyword(s):  
Gamma Radiation ◽  
Gamma Irradiation ◽  
Radiation Treatment ◽  
Reactive Dye ◽  
Iso Standard ◽  
Standard Methods ◽  
Colour Strength ◽  
Dyeing Parameters ◽  
Optimized Conditions ◽  
Temperature Time

The effect of gamma radiation on the dyeing of cotton with Reactive Blue 13 dye powder has been investigated. The cotton and dye powder are irradiated to absorb doses of 100, 200, 300, 400 and 500 Gy by using a Co-60 gamma irradiator. Dyeing is performed by using irradiated and un-irradiated cotton with irradiated and un-irradiated dye powder, in order to observe the effect of radiation treatment on the colour strength of the reactive dye on cotton. Different dyeing parameters such as temperature, time and p H are optimized using irradiated cotton and dye powder. The effect of gamma irradiation on the colour strength and Lab values has been observed through optimized conditions of dyeing. The colour strength and Lab values are obtained by spectra flash spectrophotometer (SF650). ISO standard methods are employed to study the effect of gamma radiation on the Colourfastness properties of fabric. It can be demonstrated that gamma irradiation not only improves the colour strength of the dye in irradiated cotton, but also enhances the Colourfastness properties.

The Characterization of DYRK3 mRNA and the Utility of DYRK3 Inhibitors in a Carboplatin/Radiation Mouse Model of Anemia.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 2202-2202
Author(s):  
Connie L. Erickson-Miller ◽  
Ying Homan ◽  
Matthew Chomo ◽  
Elizabeth I. Valoret ◽  
Louis Elefante ◽  
...  
Keyword(s):  
Single Dose ◽  
Mouse Model ◽  
Blood Cells ◽  
Radiation Treatment ◽  
White Blood Cells ◽  
Negative Regulator ◽  
Mrna Levels ◽  
Erythroid Progenitors ◽  
Low Levels

Abstract DYRK3, a member of the dual-specificity tyrosine phosphorylation-regulated kinase family, is expressed at low levels in erythroid progenitors and is implicated as a negative regulator of erythropoiesis. An appropriate animal model of anemia was sought to investigate the potential utility of DYRK3 inhibitors as a therapy for the treatment of anemia. Treatment of mice with sub-lethal irradiation followed by a single dose of the chemotherapeutic, nucleoside analog carboplatin, is well known to induce severe anemia. In the first instance, an analysis of DYRK3 mRNA levels was performed to ascertain whether the anemia so induced results in increased DYRK3 transcription. In this carboplatin/radiation model, mice were exposed to sub-lethal gamma irradiation (500 rads) followed by a single dose of carboplatin (60 mg/kg). This treatment induced an approximately 50% decrease in hemoglobin with concomitant drops in other erythroid parameters (hematocrit and RBC) by days 15–17. The following parameters were examined in five animals per day: peripheral blood counts, marrow cell count, plasma Epo levels, marrow Ter119+/CD71+ expression and marrow DYRK3 mRNA. As expected, the hemoglobin, hematocrit and red blood cells decreased gradually to nadir on day 15. White blood cells decreased to very low levels within 2 days of carboplatin/radiation treatment and remained suppressed for 11 days. Platelets decreased to nadir at day 7, where they remain until day 10. Plasma Epo levels were low and abruptly increased at day 3–4. The absolute number of Ter119+/CD71+ cells immediately dropped from normal levels at day 1 and then increased at day 6 and then fluctuated between a 30- to 60- fold enhancement from day 8 through 21 when the study was complete. DYRK3 mRNA, as measured by quantitative PCR (Taqman), increased approximately 10-fold at day 7 and remained in that range until day 21. The number of erythroid progenitors measured by flow cytometry,Ter119+/CD71+ cells, and the level of DYRK3 mRNA remained elevated until the end of the experiment at day 21, at which point the hemoglobin had recovered to near normal levels. GSK626616, a potent, low molecular weight inhibitor of DYRK3 kinase activity (IC50 = 0.7 nM), was dosed once daily, i.p., for 17 days in this model. At day 15, the GSK626616-treated mice (0.03 mg/kg) demonstrated a statistically significant increase in hemoglobin, hematocrit, red blood cell and platelet counts compared to anemic animals treated with vehicle alone. In contrast to its effects in anemic mice, this compound demonstrated no increases in any blood parameters in normal mice over a similar timeframe and dosage regimen. This expected behavior is hypothesized to be due to the low level of DYRK3 mRNA in normal, non-anemic mice. The characterization of this carboplatin/radiation mouse model demonstrates that as the hemoglobin decreased, plasma Epo increased at day 3–4, followed by the increase in Ter119+/CD71+ cells at day 6. Following this surge in erythropoiesis, an increase in DYRK3 mRNA expression naturally follows. The subsequent improved erythropoiesis in animals treated with a DYRK3 inhibitor in this model, suggests that DYRK3 kinase mRNA levels could have utility as a biomarker in the identification of an anemic patient population that then may be a candidate for treatment with a DYRK3 inhibitor.

scholarly journals Effect of Gamma or Beta Radiation on Salmonella DT 104 in Ground Pork†

2006 ◽  
Vol 69 (6) ◽  
pp. 1430-1433 ◽  
Author(s):  
KATHLEEN T. RAJKOWSKI ◽  
STEVEN E. NIEBUHR ◽  
JAMES DICKSON
Keyword(s):  
Gamma Radiation ◽  
Radiation Treatment ◽  
Meat Products ◽  
Fat Content ◽  
Beta Radiation ◽  
Pork Products ◽  
Radiation Sources ◽  
Significant Difference ◽  
Ground Pork ◽  
Pork Fat

Mixtures of six Salmonella Typhimurium DT 104 strains were inoculated into three ground pork products to determine the effect of fat content on the radiation resistance of Salmonella DT 104. The ground pork products were 90% lean, 50:50 fat:lean, and 100% fat. Inoculated products were irradiated using a gamma radiation source in a self-contained 137Cesium irradiator or a 10 MeV accelerator producing electrons (e-beam). The radiation D10-values (dose required for a 90% inactivation of viable CFU) for Salmonella DT 104 inoculated into 90% lean ground pork, 50:50 fat/lean ground pork, and 100% pork fat and subjected to beta radiation were 0.42 kGy, 0.43 kGy, and 0.43 kGy, respectively. The corresponding radiation D10-values for Salmonella DT 104 subject to gamma radiation were 0.56, 0.62, and 0.62 kGy, respectively. There was no statistical significant difference (P = 0.3) in radiation D10-values for Salmonella in the three products subject to either radiation treatment. Therefore, fat content had no effect. There was a significant difference (P = 0.001) between the radiation D10-values obtained with the two radiation sources. The radiation D10-values were within the reported range for irradiation destruction of Salmonella contaminated raw meat products.

scholarly journals EVALUATION OF SOME MUTANT LINES OF RICE INDUCED BY GAMMA RADIATION TREATMENT : 1- MEAN PERFORMANCE OF RICE MUTANTS IN M4 GENERATION

2009 ◽  
Vol 34 (2) ◽  
pp. 1225-1236
Author(s):  
M. N. El Banna ◽  
H. M. F. El-Wakil ◽  
R. A. Ebaid ◽  
R. A. Sallam
Keyword(s):  
Gamma Radiation ◽  
Radiation Treatment ◽  
Mutant Lines

Inactivation of Avirulent Yersinia pestis in Butterfield's Phosphate Buffer and Frankfurters by UVC (254 nm) and Gamma Radiation†

2009 ◽  
Vol 72 (4) ◽  
pp. 755-759 ◽  
Author(s):  
CHRISTOPHER H. SOMMERS ◽  
PETER H. COOKE
Keyword(s):  
Radiation Dose ◽  
Gamma Radiation ◽  
Yersinia Pestis ◽  
Phosphate Buffer ◽  
Radiation Doses ◽  
Refrigerated Storage ◽  
Log Reduction ◽  
Contaminated Food ◽  
Gamma Radiation Dose ◽  
Uvc Radiation

Yersinia pestis is the causative agent of plague. Although rare, pharyngeal plague in humans has been associated with consumption or handling of meat prepared from infected animals. The risks of contracting plague from consumption of deliberately contaminated food are currently unknown. Gamma radiation is a penetrating form of electromagnetic radiation, and UVC radiation is used for decontamination of liquids or food surfaces. Gamma radiation D10-values (the radiation dose needed to inactivate 1 log unit pathogen) were 0.23 (±0.01) and 0.31 (±0.03) kGy for avirulent Y. pestis inoculated into Butterfield's phosphate buffer and onto frankfurter surfaces, respectively, at 0°C. A UVC radiation dose of 0.25 J/cm2 inactivated avirulent Y. pestis suspended in Butterfield's phosphate buffer. UVC radiation doses of 0.5 to 4.0 J/cm2 inactivated 0.97 to 1.20 log units of the Y. pestis surface inoculated onto frankfurters. A low gamma radiation dose of 1.6 kGy could provide a 5-log reduction and a UVC radiation dose of 1 to 4 J/cm2 would provide a 1-log reduction of Y. pestis surface inoculated onto frankfurters. Y. pestis was capable of growth on frankfurters during refrigerated storage (10°C). Gamma radiation of frankfurters inhibited the growth of Y. pestis during refrigerated storage, and UVC radiation delayed the growth of Y. pestis.

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