scholarly journals Anti-inflammatory Activity of Chlorella vulgaris in Experimental models of Rats

2021 ◽  
Vol 11 (4) ◽  
pp. 358-361
Author(s):  
Swapnil Prakash Chaudhari ◽  
Dheeraj Tukaram Baviskar
Keyword(s):  
Chlorella Vulgaris ◽  
Experimental Models ◽  
Inflammatory Activity ◽  
Anti Inflammatory

scholarly journals A REVIEW ON IN VIVO AND IN VITRO EXPERIMENTAL MODELS TO INVESTIGATE THE ANTI-INFLAMMATORY ACTIVITY OF HERBAL EXTRACTS

2018 ◽  
Vol 11 (11) ◽  
pp. 29
Author(s):  
Inayat Kabir ◽  
Imtiyaz Ansari
Keyword(s):  
Reference Model ◽  
Experimental Models ◽  
Inflammatory Activity ◽  
Herbal Extracts ◽  
Double Positive ◽  
Arthritis Models ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The article emphasizes the anti-inflammatory effects of herbal extracts on different experimental models that are repeatedly used to test the in vivo anti-inflammatory activity of herbal components. Edema, granuloma and arthritis models are used to test the anti-inflammatory activity of plant extracts whereas formalin or acetic acid-induced writhing test and hot plate methods are the most repeatedly used to evaluate anti-nociceptive potentials of the herbal extracts. Although adjuvant-induced and collagen-induced arthritis models are also quite efficient, they have been used seldom to evaluate anti-inflammatory tendencies of the herbs. Here, we suggest a double positive reference model using both steroid and nonsteroidal anti-inflammatory drugs at the same time, instead of using only one of them either.

Anti-Inflammatory Activity of Raphanus sativus L in Acute and Chronic Experimental Models in Albino Rats

2013 ◽  
Vol 6 (2) ◽  
pp. 315-320 ◽  
Author(s):  
SHOBHA KAMBLE ◽  
Md. ZUBAIR AHMED ◽  
S. RAMABHIMAIAHA ◽  
PRABHAKAR PATIL
Keyword(s):  
Raphanus Sativus ◽  
Experimental Models ◽  
Inflammatory Activity ◽  
Albino Rats ◽  
Raphanus Sativus L ◽  
Anti Inflammatory

scholarly journals Secondary Metabolite Profiling, Anti-Inflammatory and Hepatoprotective Activity of Neptunia triquetra (Vahl) Benth

Molecules ◽  
2021 ◽  
Vol 26 (23) ◽  
pp. 7353
Author(s):  
Nasir Aziz Wagay ◽  
Shah Rafiq ◽  
Mohammad Aslam Rather ◽  
Younas Rasheed Tantray ◽  
Feng Lin ◽  
...  
Keyword(s):  
Total Protein ◽  
Ethanolic Extract ◽  
Liver Weight ◽  
Hepatoprotective Activity ◽  
Experimental Models ◽  
Inflammatory Activity ◽  
Albino Rats ◽  
Total Lipids ◽  
Anti Inflammatory

The present study aimed to analyze the phytoconstituents of Neptunia triquetra (Vahl) Benth. Anti-inflammatory and hepatoprotective activities of ethanol (EE), chloroform (CE) and dichloromethane (DCME) of stem extracts were evaluated using in vivo experimental models. The extracts were analyzed for phytoconstituents using GC-HRMS. Anti-inflammatory activity of CE, EE and DCME was accessed using carrageenan-induced paw oedema, cotton pellet-induced granuloma and the carrageenan-induced air-pouch model in Wistar albino rats. The hepatotoxicity-induced animal models were investigated for the biochemical markers in serum (AST, ALT, ALP, GGT, total lipids and total protein) and liver (total protein, total lipids, GSH and wet liver weight). In the in vivo study, animals were divided into different groups (six in each group) for accessing the anti-inflammatory and hepatoprotective activity, respectively. GC-HRMS analysis revealed the presence of 102 compounds, among which 24 were active secondary metabolites. In vivo anti-inflammatory activity of stem extracts was found in the order: indomethacin > chloroform extract (CE) > dichloromethane extract (DCME) > ethanolic extract (EE), and hepatoprotective activity of stem extracts in the order: CE > silymarin > EE > DCME. The results indicate that N. triquetra stem has a higher hepatoprotective effect than silymarin, however the anti-inflammatory response was in accordance with or lower than indomethacin.

scholarly journals Intestinal Anti-Inflammatory Activity of Terpenes in Experimental Models (2010–2020): A Review

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5430
Author(s):  
Maria Elaine Araruna ◽  
Catarina Serafim ◽  
Edvaldo Alves Júnior ◽  
Clelia Hiruma-Lima ◽  
Margareth Diniz ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Biological Activities ◽  
Structural Diversity ◽  
Experimental Models ◽  
New Drugs ◽  
Inflammatory Activity ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Anti Inflammatory

Inflammatory bowel diseases (IBDs) refer to a group of disorders characterized by inflammation in the mucosa of the gastrointestinal tract, which mainly comprises Crohn’s disease (CD) and ulcerative colitis (UC). IBDs are characterized by inflammation of the intestinal mucosa, are highly debilitating, and are without a definitive cure. Their pathogenesis has not yet been fully elucidated; however, it is assumed that genetic, immunological, and environmental factors are involved. People affected by IBDs have relapses, and therapeutic regimens are not always able to keep symptoms in remission over the long term. Natural products emerge as an alternative for the development of new drugs; bioactive compounds are promising in the treatment of several disorders, among them those that affect the gastrointestinal tract, due to their wide structural diversity and biological activities. This review compiles 12 terpenes with intestinal anti-inflammatory activity evaluated in animal models and in vitro studies. The therapeutic approach to IBDs using terpenes acts basically to prevent oxidative stress, combat dysbiosis, restore intestinal permeability, and improve the inflammation process in different signaling pathways.

Anti-inflammatory activity of amylin and CGRP in different experimental models of inflammation

Life Sciences ◽  
1995 ◽  
Vol 57 (14) ◽  
pp. PL193-PL197 ◽  
Author(s):  
Giuseppe Clementi ◽  
Antonina Caruso ◽  
Vincenza Maria Catena Cutuli ◽  
Agatina Prato ◽  
Ernesto de Bernardis ◽  
...  
Keyword(s):  
Experimental Models ◽  
Inflammatory Activity ◽  
Anti Inflammatory

Anti-inflammatory activity of Theobroma cacao L. stem bark ethanol extract and its fractions in experimental models

2018 ◽  
Vol 222 ◽  
pp. 239-248 ◽  
Author(s):  
Sabitiu A. Oyeleke ◽  
Abayomi M. Ajayi ◽  
Solomon Umukoro ◽  
A.O. Aderibigbe ◽  
Olusegun George Ademowo
Keyword(s):  
Theobroma Cacao ◽  
Ethanol Extract ◽  
Stem Bark ◽  
Experimental Models ◽  
Inflammatory Activity ◽  
Anti Inflammatory ◽  
Theobroma Cacao L

Anti-inflammatory activity of topical nimesulide gel in various experimental models

1996 ◽  
Vol 45 (12) ◽  
pp. 590-592 ◽  
Author(s):  
S. K. Gupta ◽  
J. Prakash ◽  
L. Awor ◽  
S. Joshi ◽  
T. Velpandian ◽  
...  
Keyword(s):  
Experimental Models ◽  
Inflammatory Activity ◽  
Anti Inflammatory
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