scholarly journals Preclinical Safety Evaluation of Acute and Subacute Intranasal Administration of Polyphenols-based Cinnamon Bark Extract in Laboratory Rats

2021 ◽  
Vol 13 (6s) ◽  
pp. 1621-1631
Author(s):  
Prasad Thakurdesai ◽  
Pallavi Deshpande
Keyword(s):  
Intranasal Administration ◽  
Safety Evaluation ◽  
Bark Extract ◽  
Cinnamon Bark ◽  
Laboratory Rats ◽  
Preclinical Safety

Preclinical safety evaluation of nafithromycin (WCK 4873) with emphasis on liver safety in rat and dog

2021 ◽  
Vol 122 ◽  
pp. 104889
Author(s):  
Manohar Nandanwar ◽  
Rajesh Chavan ◽  
Atul Kansagara ◽  
Muftedar Ahmed Patel ◽  
Anasuya Patel ◽  
...  
Keyword(s):  
Safety Evaluation ◽  
Liver Safety ◽  
Preclinical Safety

scholarly journals Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair

2021 ◽  
Vol 267 ◽  
pp. 660-668
Author(s):  
Jordan E Jackson ◽  
Christopher Pivetti ◽  
Sarah C Stokes ◽  
Christina M Theodorou ◽  
Priyadarsini Kumar ◽  
...  
Keyword(s):  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Safety Evaluation ◽  
Myelomeningocele Repair ◽  
Preclinical Safety

scholarly journals BIPOLAR MULTI-ELECTRODE BALLOON CATHETER RADIOFREQUENCY RENAL DENERVATION WITH THE VESSIX SYSTEM: PRECLINICAL SAFETY EVALUATION

2014 ◽  
Vol 63 (12) ◽  
pp. A2085
Author(s):  
Gregory J. Wilson ◽  
Dawn Winsor-Hines ◽  
Radhika Tunstall ◽  
Barbara Huibregtse ◽  
Liza Davis ◽  
...  
Keyword(s):  
Renal Denervation ◽  
Balloon Catheter ◽  
Safety Evaluation ◽  
Preclinical Safety

Preclinical safety evaluation of human platelets treated with antimicrobial peptides in severe combined immunodeficient mice

Transfusion ◽  
2013 ◽  
Vol 54 (3) ◽  
pp. 569-576 ◽  
Author(s):  
Marta Bosch-Marcé ◽  
Ketha V.K. Mohan ◽  
Monique P. Gelderman ◽  
Patricia L. Ryan ◽  
Estelle Russek-Cohen ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Safety Evaluation ◽  
Human Platelets ◽  
Immunodeficient Mice ◽  
Preclinical Safety

scholarly journals Formulasi dan Evaluasi Fisik Sediaan Emulgel Tabir Surya Ekstrak Kulit Batang Kayu Manis (Cinnamomum burmannii)

2019 ◽  
Vol 5 (1) ◽  
pp. 90-99
Author(s):  
Risqika Yuliatantri Paramawidhita ◽  
Uswatun Chasanah ◽  
Dian Ermawati
Keyword(s):  
Chemical Constituents ◽  
Physical Characteristics ◽  
Gelling Agent ◽  
Bark Extract ◽  
Cinnamon Bark ◽  
Cinnamomum Burmannii ◽  
Dispersive Power ◽  
One Way Anova ◽  
Optimal Formula ◽  
Brown Color

One of the natural ingredients can be used for sunscreen is Cinnamomum burmannii. Sinamaldehid chemical constituents in cinnamon bark extract that has potential as an antioxidant and can be used as a sunscreen content. This study was to determine the levels of cinnamon bark extract ( 1 %, 2 % and 3 % ) which can give physical characteristics, acceptability, which is optimal for preparations with HPMC as a gelling agent, Evaluations include pH, the power spread, the viscosity and acceptability. The results of organoleptic for formula I (1%), II (2%) and III (3%) have a soft texture grainy, the distinctive smell of cinnamon, and all formula has a pale brown color. From the analysis of One-Way ANOVA found significant differences for any dispersive power. But did not have significant differences in pH and viscosity. For acceptability evaluation formula III is the optimal formula to applied softness, easiest formula to flattened and easy to wash.

scholarly journals Assessment of Cinnamon (Cinnamomum verum) Bark Extract on Proximate Composition and Sensory Qualities of Smoked-Dried African Catfish Clarias gariepinus (Burchell, 1822)

2021 ◽  
pp. 1-6
Author(s):  
M. Y. Haruna ◽  
M. M. Bello ◽  
M. A. Dadile ◽  
A. M. Mohammed
Keyword(s):  
Sensory Evaluation ◽  
Proximate Composition ◽  
Clarias Gariepinus ◽  
Economic Loss ◽  
Mean Value ◽  
Carbohydrate Content ◽  
Bark Extract ◽  
African Catfish ◽  
Cinnamon Bark ◽  
Extract Solution

The study determined the effect of Cinnamon (Cinnamonum verum) bark extract solution on proximate composition and sensory evaluation of smoke-dried catfish stored at ambient temperature (37+2oC) for 28 days. The experimental treatments are the control, 0.5%, 1% and 1.5 %( w/v) cinnamon bark extract solutions. Thirty-nine fish of average mean weight of 24.87+1.25g were gutted, washed and randomly assigned to the treatments. Thereafter, the fish were soaked into the treatments for 30minutes and later hot smoked for 12hours. After smoking, the fish were stored in boxes and placed on laboratory table for one month. The catfish Clarias gariepinus treated with 1% solution of Cinnamon bark extract had the highest moisture content with mean value 13.65+0.82%, followed by 6.93+1.66% recorded in fish sample treated with 1.5% solution of the extract, lowest percentage crude protein content 38.15+0.82% was observed in fish treated with 1% concentrate of the extract and percentage carbohydrate content indicate that the control have the lowest carbohydrate content with mean value 1.92+0.01% which is significantly different (p<0.05) from other treated sample while sample treated with 1.5% solution of the Cinnamon bark extract have the highest percentage carbohydrate with mean value 15.73+1.64%.Sensory evaluation was also assessed using 7-point hedonic scale and reveals that the smoked catfish retained very good score for appearance, colour, flavour, texture and general acceptance after 28days of storage and the overall acceptability mean score in fish treated with 5g and 15g cinnamon bark extract solution indicate the product is being generally accepted (2.87+0.59%) and (2.34+0.56%) respectively. Cinnamon (Cinnamonum verum) bark extract solution could be used to protect stored smoke-dried catfish from loss of nutritional value and general acceptability thus limiting economic loss and possible health risk to consumers.

Preclinical safety evaluation of the ethanolic extract from guavira fruits (Campomanesia pubescens (D.C.) O. BERG) in experimental models of acute and short-term toxicity in rats

2018 ◽  
Vol 118 ◽  
pp. 1-12 ◽  
Author(s):  
Gustavo Roberto Villas Boas ◽  
Ariany Carvalho dos Santos ◽  
Roosevelt Isaias Carvalho Souza ◽  
Flávio Henrique Souza de Araújo ◽  
Giseli Karenina Traesel ◽  
...  
Keyword(s):  
Safety Evaluation ◽  
Ethanolic Extract ◽  
Experimental Models ◽  
Short Term ◽  
Preclinical Safety

Pharmaceutico-analytical standardization and preclinical safety evaluation of herbomineral formulation (Sameerpanag Ras) in rats

2021 ◽  
Author(s):  
Bibhakar Thakur ◽  
Swati Katoch ◽  
Sudarshan Kumar Thakur ◽  
Chander Paul Kashyap ◽  
Vikram Patial
Keyword(s):  
Safety Evaluation ◽  
Preclinical Safety
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