scholarly journals Formulasi dan Evaluasi Fisik Sediaan Emulgel Tabir Surya Ekstrak Kulit Batang Kayu Manis (Cinnamomum burmannii)

2019 ◽  
Vol 5 (1) ◽  
pp. 90-99
Author(s):  
Risqika Yuliatantri Paramawidhita ◽  
Uswatun Chasanah ◽  
Dian Ermawati
Keyword(s):  
Chemical Constituents ◽  
Physical Characteristics ◽  
Gelling Agent ◽  
Bark Extract ◽  
Cinnamon Bark ◽  
Cinnamomum Burmannii ◽  
Dispersive Power ◽  
One Way Anova ◽  
Optimal Formula ◽  
Brown Color

One of the natural ingredients can be used for sunscreen is Cinnamomum burmannii. Sinamaldehid chemical constituents in cinnamon bark extract that has potential as an antioxidant and can be used as a sunscreen content. This study was to determine the levels of cinnamon bark extract ( 1 %, 2 % and 3 % ) which can give physical characteristics, acceptability, which is optimal for preparations with HPMC as a gelling agent, Evaluations include pH, the power spread, the viscosity and acceptability. The results of organoleptic for formula I (1%), II (2%) and III (3%) have a soft texture grainy, the distinctive smell of cinnamon, and all formula has a pale brown color. From the analysis of One-Way ANOVA found significant differences for any dispersive power. But did not have significant differences in pH and viscosity. For acceptability evaluation formula III is the optimal formula to applied softness, easiest formula to flattened and easy to wash.

scholarly journals Uji efek antibakteri ekstrak kulit kayu manis (Cinnamomum burmannii) terhadap Escherichia coli dan Streptococcus pyogenes

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Noviano B. Reppi ◽  
Christi Mambo ◽  
Jane Wuisan
Keyword(s):  
Escherichia Coli ◽  
Streptococcus Pyogenes ◽  
Antibacterial Effect ◽  
Bark Extract ◽  
Inhibitory Zone ◽  
Antibacterial Compounds ◽  
Cinnamon Bark ◽  
E Coli ◽  
Inhibition Zones ◽  
Cinnamomum Burmannii

Abstract: Cinnamon (Cinnamomum burmannii) is a natural substance that has been known as one of the spices, but later known as traditional medicine. Cinnamon bark contains several antibacterial compounds, such as eugenol and cinnamaldehyde. There were two species of bacteria used in this study, Escherichia coli and Streptococcus pyogenes. These bacteria represent negative Gram bacteria and positive gram bacteria. The study aimed to determine antibacterial effect of cinamon bark againts E.coli and S.pyogenes by measuring the diameters of the inhibition zones. Cinamon bark samples were taken from Kaneyan, South Minahasa, and then be extracted by maceration using 80% etanol. The results showed that the total diameter of the inhibitory zone of Cinamon bark extract against E.coli was 43 mm with an average of 14,3 mm, and the total diameter of the inhibitory zone against S.pyogenes was 75 mm with an average of 25 mm. Conclusion: Cinamon bark extract had antibacterial effect against E Escherichia coli and Streptococcus pyogenes. Keywords: cinamon bark, escherichia coli, streptococcus pyogenes,antibacterial effect. Abstrak: Kayu manis (Cinnamomum burmannii) merupakan bahan alami yang selama ini hanya dikenal sebagai bumbu dalam masakan, tetapi ternyata memiliki khasiat obat. Kulit kayu manis mengandung beberapa senyawa yang bersifat antibakteri, seperti eugenol dan cinnamaldehyde. Bakteri Escherichia coli dan Streptococcus pyogenes merupakan bakteri yang digunakan didalam peneilitian ini. Kedua bakteri ini mewakili bakteri Gram negatif dan positif. Penelitian ini bertujuan untuk mengetahui efek antibakteri kulit kayu manis terhadap E. coli dan S. pyogenes, yang dinilai dari besarnya zona hambat yang terbentuk. Jenis penelitian ini eksperimental dengan metode sumuran Kirby-Bauer. Sampel kulit kayu manis diambil dari daerah Kaneyan Kabupaten Minahasa Selatan, kemudian diekstraksi dengan metode maserasi menggunakan pelarut etanol 80%. Hasil penelitian memperlihatkan diameter zona hambat total dari ekstrak kulit kayu manis terhadap E. coli sebesar 43mm dengan rerata 14,3mm, dan terhadap S. pyogenes diameter zona hambat total 75mm dengan rerata 25mm. Simpulan: Ekstrak kulit kayu manis memiliki efek antibakteri dalam menghambat pertumbuhan Escherichia coli dan Streptococcus pyogenesKata kunci: kulit kayu manis, Escherichia coli, Streptococcus pyogenes, antibakteri

scholarly journals The development of antioxidant peel-off facial masks from cinnamon bark extract (Cinnamomum burmannii)

Pharmaciana ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 69
Author(s):  
Sani Ega Priani ◽  
Restianti Mutiara Mutiara ◽  
Dina Mulyanti
Keyword(s):  
Bark Extract ◽  
Cinnamon Bark ◽  
Cinnamomum Burmannii

scholarly journals Thin-layer hydration method to prepare a green tea extract niosomal gel and its antioxidant performance

2021 ◽  
Vol 68 (1) ◽  
pp. 126-136
Author(s):  
U. Chasanah ◽  
N. Mahmintari ◽  
F. Hidayah ◽  
F.A. El Maghfiroh ◽  
D. Rahmasari ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Thin Layer ◽  
Green Tea ◽  
Chorioallantoic Membrane ◽  
Entrapment Efficiency ◽  
Physical Characteristics ◽  
Green Tea Extract ◽  
Gelling Agent ◽  
Niosomal Gel ◽  
Tea Extract

Abstract This study aimed to prepare a niosomal gel of green tea (Camellia sinensis) extract containing catechins, mostly epigallocatechin-3-gallate (ECGC), as a potent antioxidant. Niosomes can increase EGCG's stability and penetration into the skin for a better therapeutic effect. Niosomes were prepared by a thin-layer hydration method, were evaluated for their vesicle shape, particle size, polydispersity index, zeta potential and entrapment efficiency, and then incorporated into gels using sodium alginate as a gelling agent. Three niosomal gel formulations were prepared with different concentrations of niosomes green tea extract. Afterwards, organoleptic properties, chemical and physical characteristics, antioxidant activity, and stability and irritability of the niosomal gels were investigated. The different concentrations of green tea extract had a significant effect on the physical characteristics, but not on the chemical ones. Its antioxidant activity was determined using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging method. The 50% extract green tea niosomes gel showed the highest inhibition value (25.13%). The stability was determined by freeze–thaw and real-time methods; they showed a decrease in pH, but still within the pH range of skin. The irritability test used was the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) method, which showed no irritation for all formulas. In conclusion, 50% green tea extract niosomes gel results showed it to be the best formulation with optimal antioxidant results.

scholarly journals FORMULASI MASKER GEL PEEL-OFF PERASAN LIDAH BUAYA (Aloe vera L.) DENGAN GELLING AGENT POLIVINIL ALKOHOL

2020 ◽  
Vol 2 (1) ◽  
pp. 17-25
Author(s):  
Ivan Santoso ◽  
Tria Prayoga ◽  
Ika Agustina ◽  
Wiwit Setya Rahayu
Keyword(s):  
Polyvinyl Alcohol ◽  
Aloe Vera ◽  
The Other ◽  
Local People ◽  
Gelling Agent ◽  
Drying Time ◽  
Other Hand ◽  
One Way Anova ◽  
Made In

Aloe vera (Aloe Vera L.) is a plant which commonly used by local people as moisturizer. The usage of aloe vera can be applied in form of peeled off gel mask with polyvinyl alcohol as gelling agent. The goal of this research is to determine the influence of increase of polyvinyl alcohol as gelling agent to the formulation of peeled off mask from aloe vera juice. The formulation was made in a few concentration, 10%, 12%, and 14% by adding 0,5% of aloe vera juice. After that, the formulation evaluated for 4 weeks about the organoleptics, homogenity, pH, drying time and viscosity. The date of pH test and drying time analyzed by using one way ANOVA statistically and then followed by Tukey HSD test and the viscosity analyzed by using Kruskall Wallis statistically which result in the significantcy less than 0,05 that mean there are difference in drying time and viscosity, on the other hand there is no difference in pH.

scholarly journals Assessment of Cinnamon (Cinnamomum verum) Bark Extract on Proximate Composition and Sensory Qualities of Smoked-Dried African Catfish Clarias gariepinus (Burchell, 1822)

2021 ◽  
pp. 1-6
Author(s):  
M. Y. Haruna ◽  
M. M. Bello ◽  
M. A. Dadile ◽  
A. M. Mohammed
Keyword(s):  
Sensory Evaluation ◽  
Proximate Composition ◽  
Clarias Gariepinus ◽  
Economic Loss ◽  
Mean Value ◽  
Carbohydrate Content ◽  
Bark Extract ◽  
African Catfish ◽  
Cinnamon Bark ◽  
Extract Solution

The study determined the effect of Cinnamon (Cinnamonum verum) bark extract solution on proximate composition and sensory evaluation of smoke-dried catfish stored at ambient temperature (37+2oC) for 28 days. The experimental treatments are the control, 0.5%, 1% and 1.5 %( w/v) cinnamon bark extract solutions. Thirty-nine fish of average mean weight of 24.87+1.25g were gutted, washed and randomly assigned to the treatments. Thereafter, the fish were soaked into the treatments for 30minutes and later hot smoked for 12hours. After smoking, the fish were stored in boxes and placed on laboratory table for one month. The catfish Clarias gariepinus treated with 1% solution of Cinnamon bark extract had the highest moisture content with mean value 13.65+0.82%, followed by 6.93+1.66% recorded in fish sample treated with 1.5% solution of the extract, lowest percentage crude protein content 38.15+0.82% was observed in fish treated with 1% concentrate of the extract and percentage carbohydrate content indicate that the control have the lowest carbohydrate content with mean value 1.92+0.01% which is significantly different (p<0.05) from other treated sample while sample treated with 1.5% solution of the Cinnamon bark extract have the highest percentage carbohydrate with mean value 15.73+1.64%.Sensory evaluation was also assessed using 7-point hedonic scale and reveals that the smoked catfish retained very good score for appearance, colour, flavour, texture and general acceptance after 28days of storage and the overall acceptability mean score in fish treated with 5g and 15g cinnamon bark extract solution indicate the product is being generally accepted (2.87+0.59%) and (2.34+0.56%) respectively. Cinnamon (Cinnamonum verum) bark extract solution could be used to protect stored smoke-dried catfish from loss of nutritional value and general acceptability thus limiting economic loss and possible health risk to consumers.

Stability and functionality of xanthan gum–shellac nanoparticles for the encapsulation of cinnamon bark extract

2020 ◽  
Vol 100 ◽  
pp. 105377 ◽  
Author(s):  
Dimas Rahadian Aji Muhammad ◽  
Ali Sedaghat Doost ◽  
Vipul Gupta ◽  
Mohd Dona bin Sintang ◽  
Davy Van de Walle ◽  
...  
Keyword(s):  
Xanthan Gum ◽  
Bark Extract ◽  
Cinnamon Bark

scholarly journals EFFICACY AND SAFETY OF STANDARDIZED CINNAMON BARK EXTRACT FOR THE PREVENTION OF CHEMOTHERAPY-INDUCED WEIGHT LOSS AND ALOPECIA IN PATIENTS WITH BREAST CANCER: A RANDOMIZED, DOUBLE-BLIND, AND PLACEBO-CONTROLLED STUDY

2019 ◽  
pp. 163-168
Author(s):  
AJAY MEHTA ◽  
SUCHITRA MEHTA ◽  
PRASAD THAKURDESAI
Keyword(s):  
Breast Cancer ◽  
Weight Loss ◽  
Side Effects ◽  
Cancer Patients ◽  
Outcome Measures ◽  
Bark Extract ◽  
Efficacy And Safety ◽  
Breast Cancer Patients ◽  
Double Blind ◽  
Cinnamon Bark

Objective: The objective of the study was to evaluate the effects of IND02 (standardized Cinnamon bark extract) supplementation for the prevention of side effects of cancer chemotherapy in female patients with breast cancer. Methods: The study was conducted using double-blind, placebo-controlled design in 34 female breast cancer patients during the first 4 consecutive 21-day cycles of the standard chemotherapy regimen. The active treatment (IND02 capsules, 400 mg, one capsule, and thrice a day) or matching placebo was orally administrated in randomized (1:1 ratio) patients. The efficacy outcome measures were reduction in chemotherapy-induced weight loss, alopecia (hair fall), and other side effects. The safety outcome measures were hematology, ECG, vital signs, adverse event monitoring, and laboratory safety measurements. Results: The patients on the treatment with IND02 had shown significant protection from chemotherapy-induced severe weight loss (cachexia) and alopecia (reduced hair density and % hairs in the anagen phase, and increased % hairs in telogen phase) which was seen in the placebo group. IND02 treatment was found safe and well-tolerated during the study. Conclusion: Concomitant use of IND02 in breast cancer patients during breast cancer chemotherapy showed a clinical promise regarding efficacy and safety in preventing chemotherapy-induced weight loss and alopecia.

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