scholarly journals Dental Caries among Tasters and Non-Tasters of PTC Substance in Students of Qurna Population

2019 ◽  
Vol 9 (1) ◽  
pp. 82
Author(s):  
Hasna Amir Mohaus
Keyword(s):  
Dental Caries ◽  
Early Detection ◽  
Secondary Students ◽  
Significant Relationship ◽  
Caries Prevention ◽  
Future Research ◽  
Human Populations ◽  
Daily Routine ◽  
Age Group ◽  
Dietary Regimen

Objective: Dental caries is one of the most common diseases found in human populations and it is still prevalent and widespread in all around the world. newer strategies emphasize disease prevention as a model of disease management. For early detection and monitoring of caries rather than treatment Taste has valuable roles in our lives in health and disease. genetic markers such as PTC substance taste ability may represent a useful tool to predict the susceptibility to caries. This study aims to investigate the relationship between the taste ability of phenylthiocarbamide (PTC) substance and dental caries. Materials and Methods: The current study was conducted from November 2017 to April 2018 in Qurna and Madiana population/Basrah/Iraq, PTC taste sensitivity was determined among random sample of (406) student from primary and secondary schools; 216 males and 190 females, their ages ranging from (6-17) years old. For dental caries assessment, dmft/DMFT scores were recorded. Individuals were divided into three groups (low, high and very high) according to their dental caries severity in addition to the free caries individuals. Results: The proportion of tasters were higher as compared to non-tasters in this sample. The results showed an increase in the prevalence of caries among primary(68%) and secondary (57.6%) school’s students respectively and for both of them (64.03%). In primary school; females had an elevated percentage of caries (73.1%) compared to their counterpart males (65%). The results of this study did not show a significant relationship between the taste of PTC substance and dental caries, with equal proportions of caries prevalence among tasters and non-tasters (P > 0.05). However, the results showed significant differences in age effect in the prevalence of dental caries among primary and secondary students as it increased in individuals of the age group (6-12) years compared to the age group (13-17) years. Conclusion: The results of this study did not show a significant relationship between the taste of PTC substance and dental caries. In other hand age have a significant influence especially in primary age school and females were more affected than males. The appearance of the two phenotypes of PTC taste may be due to the involvement of other genes, rather than the PTC gene only, including CA6 gene and its variation , which in turn affects the pH capacity of the saliva, a factor associated with tooth decay. Due to the multifactorial nature of dental caries, the individual’s vulnerability may differ from one to another. In addition, particularly regarding diet, part of the strategy to be adopted can be defined as health promotion by preventing the occurrence of the disease rather than treatment. Integrating a healthy dietary regimen into the daily routine can have a real influence on oral health and can be regarded as a primary step towards caries prevention. future research efforts should continue to emphasize early detection and caries prevention strategies.

scholarly journals A Systematic Review and Meta-Analysis of the Role of Sugar-Free Chewing Gum in Dental Caries

2019 ◽  
Vol 5 (3) ◽  
pp. 214-223
Author(s):  
J.T. Newton ◽  
O. Awojobi ◽  
M. Nasseripour ◽  
F. Warburton ◽  
S. Di Giorgio ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Caries ◽  
Meta Analysis ◽  
National Policy ◽  
Public Health Intervention ◽  
Caries Prevention ◽  
Future Research ◽  
Caries Increment ◽  
The Difference ◽  
High Level

Objective: To determine the difference in level of dental caries in adults and children who chew sugar-free gum (SFG), compared with those who do not chew SFG or use alternatives such as lozenges, candies, rinses, tablets, and other nonchewing controls. Methods: Systematic review of published literature. Results: Twelve studies of interventions of SFG for dental caries outcomes were included. SFGs were found to significantly reduce caries increment, giving a preventative fraction (PF) of 28% (95% CI, 7% to 48%). Including the 8 trials that used xylitol gum only as the basis of the intervention, the PF was 33% (95% CI, 4% to 61%). No adverse effects were recorded. There was a high level of heterogeneity among the trials included. Conclusion: The findings of this review provide tentative evidence that chewing SFG reduces caries increment in comparison to nonchewing controls. However, there is a considerable degree of variability in the effect and the trials included were generally of moderate quality. There is a need for future research to explore the acceptability and feasibility of the use of SFG as a public health intervention (PROSPERO 2018 CRD42018094676). Knowledge Transfer Statement: The results of this study can be used by clinicians when deciding how best to implement dental caries prevention regimes for their patients. With consideration of cost and patient preference, this information could help to develop national policy directives on caries prevention and dictate the direction of future clinical research.

scholarly journals Prevention of dental caries by grape seed extract supplementation: A systematic review

2019 ◽  
Vol 26 (1) ◽  
pp. 43-52 ◽  
Author(s):  
Nicole M Delimont ◽  
Brandi N Carlson
Keyword(s):  
Systematic Review ◽  
Dental Caries ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Caries Prevention ◽  
Future Research ◽  
Preventative Care ◽  
Tooth Surfaces ◽  
Human Participants

Background: Dental caries are the most prominent chronic disease of children and adults worldwide, and facilitating evidence-based, preventative care for their prevention is critical. Caries are traditionally and successfully prevented by regular fluoride use, but there are opportunities to halt and restore caries with alternative agents in addition to fluoride use. Grape seed extract (GSE) is a readily available plant-based supplement that, due to its concentrated levels of proanthocyanidins, has promising characteristics that may assist in dental caries prevention. Aim: The goal of this review was to investigate whether current research supports use of grape seed extract to prevent dental caries formation. Methods: A systematic review of articles related to grape seed extract, prevention of dental caries, inhibition of Streptococcus mutans, and remineralization was conducted. Articles were first chosen by inclusion of dental models that used grape seed extract as an intervention, and then by strength of study design. Results: Twenty articles were reviewed. Studies overall supported three unique grape seed extract properties facilitating dental caries prevention. In the first articles reviewed, grape seed extract inhibited proliferation of bacterial biofilms on tooth surfaces. In addition, studies reviewed indicated that grape seed extract promoted dental remineralization. Conclusions: Caries prevention by grape seed extract may be unique compared with fluoride, and is linked to grape seed extract’s bacteriostatic and collagen crosslinking properties. Future research should investigate potential delivery methods, and benefits of combined grape seed extract use with known caries preventative agents, in human participants.

scholarly journals Probiotics, Prebiotics, Synbiotics and Dental Caries. New Perspectives, Suggestions, and Patient Coaching Approach for a Cavity-Free Mouth

2021 ◽  
Vol 11 (12) ◽  
pp. 5472
Author(s):  
Markos Amargianitakis ◽  
Maria Antoniadou ◽  
Christos Rahiotis ◽  
Theodoros Varzakas
Keyword(s):  
Dental Caries ◽  
Caries Prevention ◽  
Daily Routine ◽  
Liquid Form ◽  
Antimicrobial Substances ◽  
Dental Patients ◽  
New Strategy ◽  
Sugary Beverages ◽  
Clinical Potential ◽  
Coaching Approach

Probiotic therapy forms a new strategy for dental caries prevention. Probiotic microorganisms possess the ability to displace cariogenic microorganisms and colonize the oral cavity. They can produce various antimicrobial substances such as bacteriocins, bacteriocin-like peptides, lactic acid, and hydrogen peroxide. Dairy products may be ideal for probiotic administration in dental patients. Many other means have been proposed, primarily for those allergic to dairy components, such as capsules, liquid form, tablets, drops, lozenges, sweetened cakes, and ice creams. The last two forms can be used in a coaching approach for children and elderly patients who find it difficult to avoid sugary beverages in their daily routine and benefit from the suggestion of easy, cheap, and common forms of delicacies. In caries prevention, the concept of the effector strain is already considered an integral part of the contemporary caries cure or prevention strategy in adults. Adults, though, seem not to be favored as much as children at early ages by using probiotics primarily due to their oral microbiome’s stability. In this non-systematic review we describe the modes of action of probiotics, their use in the cariology field, their clinical potential, and propose options to prevent caries through a patient coaching approach for the daily dental practice.

Potential Role of Cytokines in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis

2011 ◽  
Vol 11 (1) ◽  
pp. 130-133
Author(s):  
Astra Zviedre ◽  
Arnis Engelis ◽  
Mohit Kakar ◽  
Aigars Pētersons
Keyword(s):  
Early Detection ◽  
Acute Appendicitis ◽  
Inflammatory Mediators ◽  
Potential Role ◽  
Clinical Symptoms ◽  
Future Research ◽  
Mesenteric Lymphadenitis ◽  
Proper Diagnosis ◽  
Near Future

Potential Role of Cytokines in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis Although, AAP and AML have different etiological factors, clinical symptoms are very much similar but treatment tactics in both the disease differ a lot. In case of AML, treatment is more conservative and does not require hospitalization while in case of AAP immediate hospitalization and maybe further surgery can be mandatory. With the identification of group of cytokines serum inflammatory mediators IL-8, IL-10, IL-12[p70], IL-17, TNF-a and MCP-1, it is believed early and proper diagnosis of AAP in the near future. Research of cytokines-serum inflammatory mediators has opened new opportunities for an early detection and differentiation of these two diseases in children.

scholarly journals Human Prehistoric Demography Revealed by the Polymorphic Pattern of CpG Transitions

2020 ◽  
Vol 37 (9) ◽  
pp. 2691-2698 ◽  
Author(s):  
Xiaoming Liu
Keyword(s):  
Population Dynamics ◽  
Population Expansion ◽  
Future Research ◽  
Human Populations ◽  
Neolithic Revolution ◽  
Cpg Sites ◽  
Hunting And Gathering ◽  
Genome Wide ◽  
Polymorphic Pattern ◽  
Improved Model

Abstract The prehistoric demography of human populations is an essential piece of information for illustrating our evolution. Despite its importance and the advancement of ancient DNA studies, our knowledge of human evolution is still limited, which is also the case for relatively recent population dynamics during and around the Holocene. Here, we inferred detailed demographic histories from 1 to 40 ka for 24 population samples using an improved model-flexible method with 36 million genome-wide noncoding CpG sites. Our results showed many population growth events that were likely due to the Neolithic Revolution (i.e., the shift from hunting and gathering to agriculture and settlement). Our results help to provide a clearer picture of human prehistoric demography, confirming the significant impact of agriculture on population expansion, and provide new hypotheses and directions for future research.

Irradiation methods of 10,600 nm carbon dioxide laser for dental caries prevention

2021 ◽  
Author(s):  
Kenneth Luk ◽  
Irene Shuping Zhao ◽  
Iris Xiaoxue Yin ◽  
John Yun Niu ◽  
Norbert Gutknecht ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Dental Caries ◽  
Carbon Dioxide Laser ◽  
Caries Prevention

scholarly journals 229 Sleep-wake behavior, meal timings and digital media duration of Indians during COVID-19 Lockdown

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A91-A92
Author(s):  
Babita Pande ◽  
Meenakshi Sinha ◽  
Ramanjan Sinha
Keyword(s):  
Digital Media ◽  
Sleep Duration ◽  
Sleep Onset ◽  
Therapeutic Management ◽  
Daily Routine ◽  
Age Group ◽  
Younger Age ◽  
Gender And Age ◽  
Delayed Sleep ◽  
The Impact

Abstract Introduction Lockdown and stay home order has been imposed on people in many countries including India to prevent the community transmission of COVID-19 pandemic. However this social restriction led to disturbed daily routine and lifestyle behaviour that is needed to be attended for proper therapeutic management of overall health during such crisis. The impact of lockdown on the most apparent behavioral changes viz. sleep-wake behaviour, major meal timings, and digital screen duration of Indians were investigated. In addition the effects of gender and age were explored. Methods After seeking permission from Ethical Institution, an online questionnaire based survey was circulated within India in the first week of May, 2020 for which total 1511 male and female (age ≥18 years) subjects participated. The sleep-wake behavior observed were sleep-wake timings, sleep duration, mid sleep time (MST) as function of lockdown, and social (lockdown) jetlag (SJL = MST before lockdown-MST during lockdown). Results The sleep onset-wakeup and meal times were significantly delayed during lockdown, which was more pronounced in younger age group. The sleep duration increased, specifically in young individuals during lockdown. Females showed more delayed sleep onset-waking times and first meal timing with longer sleep duration during lockdown. Increased digital media duration was observed in all age groups, primarily in males. The younger age group and specifically female reported higher SJL and delayed MST. A positive association was obtained between sleep duration & first meal time, and SJL & major meal timings/screen duration, and a significant negative relationship of sleep duration and SJL with age. Conclusion The study shows delayed sleep-wake schedule, meal timings and increased digital media duration among Indians during COVID-19 lockdown compared to before lockdown. Also, gender and age emerged as important mediating factors for this alteration. The pandemic has given opportunity to sleep more and compensate for the sleep. In spite of that, the higher social jetlag in young age group and female showed the compromised sleep and maladaption with societal timing. These findings have applied implications in sleep health during longer social isolation conditions and for proper therapeutic management. Support (if any) No

Correlations between Speakers' Body Size and Acoustic Parameters of Voice

2007 ◽  
Vol 105 (1) ◽  
pp. 215-220 ◽  
Author(s):  
Julio Conzález
Keyword(s):  
Body Size ◽  
Significant Relationship ◽  
The Body ◽  
Age Group ◽  
Acoustic Parameters ◽  
Acoustic Measures ◽  
Age And Sex

Generally, there is a significant relationship between some acoustic measures (F0 and formant parameters) and the body size of speakers; however, data become less clear when age and sex variables are controlled. To date, no other vocal parameter apart from F0 has been studied in relation to body size. In the present study, correlations between a set of 27 parameters of the Multi-dimensional Voice Program (Kay Elemetrics Corp.) and 4 body measures were obtained from 134 speakers of both sexes belonging to one age group (20–29 years). Correlations within sex groups were null or very weak, and all significant coefficients were below .35.

Consumer perception of portable ladder hazards and warnings

2018 ◽  
Vol 62 (1) ◽  
pp. 411-415
Author(s):  
Kenneth Nemire
Keyword(s):  
Significant Relationship ◽  
Online Survey ◽  
Consumer Perceptions ◽  
Consumer Perception ◽  
Mechanical Turk ◽  
Amazon Mechanical Turk ◽  
Future Research ◽  
Warning Labels ◽  
Preliminary Assessment ◽  
Survey Tool

This article describes the results of a survey intended as a preliminary assessment of consumer perceptions of the hazardousness of portable ladders and the warning labels provided on portable ladders. One hundred ten participants responded to an online survey tool called Amazon Mechanical Turk. The survey collected information about participants’ use of ladders, their ratings of familiarity with ladders, perceived hazardousness of portable ladders, and perception of warning labels on portable ladders. Results indicated a small but significant relationship between familiarity with ladders and their perceived hazardousness, and that participants thought that people should be warned about the hazards associated with ladder use. Implications for future research about consumer perception of portable ladder hazards and warnings are described.

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