Hepatocellular Carcinoma and Associated Clinical Features in Latino and Caucasian Patients from a Single Center

Introduction and aim. Hepatocellular carcinoma (HCC) is the most common type of liver cancer in adults and has seen a rapid increase in incidence in the United States. Racial and ethnic differences in HCC incidence have been observed, with Latinos showing the greatest increase over the past four decades, highlighting a concerning health disparity. The goal of the present study was to compare the clinical features at the time of diagnosis of HCC in Latino and Caucasian patients. Material and methods. We retrospectively screened a total of 556 charts of Latino and Caucasian patients with HCC. Results. The mean age of HCC diagnosis was not significantly different between Latinos and Caucasians, but Latinos presented with higher body mass index (BMI). Rates of hypertension, diabetes, and hyperlipidemia were similar in the two groups. The most common etiology of liver disease was alcohol drinking in Latinos, and chronic hepatitis C in Caucasian patients. Non-Alcoholic Steatohepatitis (NASH) was the associated diagnosis in 8.6% of Latinos and 4.7% of Caucasians. Interestingly, alpha-fetoprotein (AFP) levels at time of diagnosis were higher in Latino patients compared to Caucasians, but this difference was evident only in male patients. Multifocal HCC was slightly more frequent in Latinos, but the two groups had similar cancerous vascular invasion. Latino patients also presented with higher rates of both ascites and hepatic encephalopathy. Conclusion. Latino and Caucasian patients with HCC present with a different profile of etiologies, but cancer features appear to be more severe in Latinos.

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Racial and Ethnic Differences in Blood Pressure Among US Adults, 1999–2018

Hypertension ◽

10.1161/hypertensionaha.121.18086 ◽

2021 ◽

Author(s):

Shakia T. Hardy ◽

Ligong Chen ◽

Andrea L. Cherrington ◽

Nathalie Moise ◽

Byron C. Jaeger ◽

...

Keyword(s):

Blood Pressure ◽

Ethnic Differences ◽

Antihypertensive Medication ◽

The United States ◽

Black Adults ◽

Racial And Ethnic Differences ◽

Hispanic Adults ◽

The Mean ◽

White Adults ◽

Hispanic White

Racial and ethnic differences in blood pressure (BP), regardless of antihypertensive medication use, contribute to cardiovascular disease disparities. We analyzed systolic BP (SBP) data from US adults in the National Health and Nutrition Examination Survey from 1999 to 2002 through 2015 to 2018 (n=51 743) to determine if racial and ethnicity disparities have changed over time. Among US adults not taking antihypertensive medication, the mean age-adjusted SBP (95% CI), mm Hg, in 1999 to 2002 and 2015 to 2018 was 119.6 (118.7–120.5) and 119.4 (118.7–120.1) for non-Hispanic White adults, 124.7 (123.7–125.7) and 124.9 (123.8–125.9) for non-Hispanic Black adults and 120.4 (118.6–122.2) and 120.4 (119.7–121.2) for Hispanic adults. The mean multivariable-adjusted SBP was 4.1 mm Hg (2.7–5.4) higher in 1999 to 2002 and 3.8 mm Hg (2.6–5.0) higher in 2015 to 2018 among non-Hispanic Black adults compared with non-Hispanic White adults, while there was no evidence of a difference between Hispanic adults and non-Hispanic White adults in 1999 to 2002 (−0.2 mm Hg [95% CI, −1.9 to 1.5]) or 2015 to 2018 (−0.8 mm Hg [95% CI, −1.8 to 0.1]). Among US adults taking antihypertensive medication, the mean age-adjusted SBP (95% CI), mm Hg, in 1999 to 2002 and 2015 to 2018 was 129.6 (126.7–132.4) and 127.1 (125.6–128.6) for non-Hispanic White adults, 136.9 (133.8–140.0) and 135.3 (132.5–138.1) for non-Hispanic Black adults and 133.9 (128.0–139.7) and 131.8 (127.6–136.0) for Hispanic adults. After multivariable adjustment, in 1999 to 2002 and 2015 to 2018, mean SBP was 4.8 mm Hg (1.8–7.8) and 6.5 mm Hg (4.5–8.4) higher, respectively, among non-Hispanic Black adults versus White adults, and 2.4 mm Hg (−2.6 to 7.3) and 3.6 mm Hg (0.8 to 6.4) higher, respectively, among Hispanic adults versus non-Hispanic White adults. In the United States, non-Hispanic Black adults continue to have higher SBP levels compared with non-Hispanic White adults.

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Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

10.21203/rs.3.rs-117309/v1 ◽

2020 ◽

Author(s):

Guner Cakmak ◽

Baris Mantoglu ◽

Emre Gonullu ◽

Kayhan Ozdemir ◽

Burak Kamburoglu

Keyword(s):

Acute Appendicitis ◽

Clinical Features ◽

Total Bilirubin ◽

Negative Appendectomy ◽

C Reactive Protein ◽

Future Studies ◽

Female Patients ◽

Reactive Protein ◽

Male Patients ◽

The Mean

Abstract Background: The objective of this study was to retrospectively compare clinical features and prognostic values between the patients who were referred to the general surgery clinic of our hospital with the presumed diagnosis of acute appendicitis and underwent positive or negative appendectomy.Methods: Patients were divided into two groups as positive (PA) (n:362) and negative appendectomy (NA) (n:284) and the data obtained were compared between these two groups.Laboratory investigations were performed in all patients, and white blood cell (WBC), mean platelet volume (MPV), neutrophils count (NEU), neutrophils (%) (NEU%), C-reactive protein (CRP) and total bilirubin (TBIL) values were studied.Results: The mean MPV value was found as 7.88 fl in PA groups and 8.09 fl in NA group, and the mean MPV value was not statistically significantly difference in PA group, compared to NA groups (p=0.012). Laboratory parameters were also compared between genders. Accordingly, the mean MPV value was statistically significantly higher in female patients compared to male patients in PA group (p = 0.04). The mean TBIL value was 0.97 mg/dl in PA group and 0.69 mg/dl in NA group, and the mean TBIL value was statistically significantly higher in PA group (p< 0.001). Finally, TBIL value was statistically significantly lower in female patients compared to male patients in NA and PA group (p < 0.05).Conclusions: According to the results of our study, MPV and T. BIL values differ in PA and NA groups depending on gender. Therefore, these values may not be used as specific biomarkers in predicting positive acute appendicitis. We believe that these results will contribute to the literature and will be guiding for future studies.

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Measuring and explaining racial and ethnic differences in willingness to donate live kidneys in the United States

Clinical Transplantation ◽

10.1111/ctr.12196 ◽

2013 ◽

pp. n/a-n/a ◽

Cited By ~ 1

Author(s):

Tanjala S. Purnell ◽

Neil R. Powe ◽

Misty U. Troll ◽

Nae-Yuh Wang ◽

Carlton Haywood ◽

...

Keyword(s):

United States ◽

Ethnic Differences ◽

The United States ◽

Racial And Ethnic Differences ◽

Willingness To Donate

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Racial and ethnic differences in genetic counseling experiences and outcomes in the United States: A systematic review

Journal of Genetic Counseling ◽

10.1002/jgc4.1230 ◽

2020 ◽

Vol 29 (2) ◽

pp. 147-165

Author(s):

Sabrina V. Southwick ◽

Riley Esch ◽

Rachel Gasser ◽

Deborah Cragun ◽

Krista Redlinger‐Grosse ◽

...

Keyword(s):

United States ◽

Systematic Review ◽

Genetic Counseling ◽

Ethnic Differences ◽

The United States ◽

Racial And Ethnic Differences

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Distrust and Empathy: Explaining the Lack of Support for Capital Punishment Among Minorities

Criminal Justice Review ◽

10.1177/0734016818796902 ◽

2018 ◽

Vol 44 (2) ◽

pp. 204-230 ◽

Cited By ~ 1

Author(s):

Wanda D. Foglia ◽

Nadine M. Connell

Keyword(s):

Ethnic Differences ◽

Capital Punishment ◽

Justice System ◽

The United States ◽

White Americans ◽

Racial And Ethnic Differences ◽

Capital Jury ◽

Using Data ◽

Public Opinion Polls ◽

Opinion Polls

Public opinion polls show that the majority of people in the United States support capital punishment but that is because the majority of White Americans support it. Research on the opinions of non-Whites consistently finds less support. We examine racial and ethnic differences among people who actually had to decide whether to impose the death penalty, former capital jurors, and hypothesize that lower support among non-Whites can be explained by the fact that non-Whites are more likely to distrust the criminal justice system and more likely to show empathy for the defendant in a capital case, net of defendant and victim race. Using data from the Capital Jury Project, we find support for this hypothesis in a mediating relationship between race and sentencing vote. Black and Hispanic jurors are more likely to report distrust of the capital process and higher levels of empathy for the defendant, both of which lower the probability of a death vote during the sentencing phase of the trial. We discuss the implications for research, trial strategy, and the future of capital punishment in light of these findings.

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Racial and ethnic differences in motivation for educational achievement in the United States

Personality and Individual Differences ◽

10.1016/s0191-8869(99)00051-3 ◽

1999 ◽

Vol 27 (6) ◽

pp. 1091-1096 ◽

Cited By ~ 7

Author(s):

Wei-Cheng Mau ◽

Richard Lynn

Keyword(s):

United States ◽

Ethnic Differences ◽

Educational Achievement ◽

The United States ◽

Racial And Ethnic Differences

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Racial and ethnic differences in the relationship between antenatal stressful life events and postpartum depression among women in the United States: does provider communication on perinatal depression minimize the risk?

Ethnicity and Health ◽

10.1080/13557858.2017.1280137 ◽

2017 ◽

Vol 23 (5) ◽

pp. 542-565 ◽

Cited By ~ 5

Author(s):

Soumyadeep Mukherjee ◽

Kristopher Fennie ◽

Stefany Coxe ◽

Purnima Madhivanan ◽

Mary Jo Trepka

Keyword(s):

United States ◽

Postpartum Depression ◽

Life Events ◽

Ethnic Differences ◽

Stressful Life Events ◽

Perinatal Depression ◽

The United States ◽

Provider Communication ◽

Racial And Ethnic Differences ◽

The Relationship

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Race and Ethnic Differences in Adolescent Drug Use: The Impact of Family Structure and the Quantity and Quality of Parental Interaction

Journal of Drug Issues ◽

10.1177/002204269802800202 ◽

1998 ◽

Vol 28 (2) ◽

pp. 283-298 ◽

Cited By ~ 55

Author(s):

Cheryl H. Amey ◽

Stan L. Albrecht

Keyword(s):

Drug Use ◽

Ethnic Differences ◽

Black Family ◽

Household Survey ◽

The United States ◽

Family Characteristics ◽

Racial And Ethnic Differences ◽

Adolescent Drug Use ◽

National Priority ◽

The Impact

Curbing adolescent substance abuse is a national priority in the United States. To effectively allocate resources it is imperative that antecedents and correlates of drug use across diverse populations be understood. Racial and ethnic differences in drug use have yet to be explained. Because family characteristics are known to vary across race/ethnic groups, and prior research suggests a connection between family characteristics and adolescent drug use, this study investigates the impact of family on race/ethnic differences in drug use. Using data from a national household survey, we found that although socioeconomic and demographic characteristics alone explained drug use differences between Latinos and non-Latino whites, the differences between Black and white adolescents could not be explained by either structural or functional differences in the family. Furthermore, it appears that the single-parent Black family provides a greater protection against drug use than does the two-biological-parent Black family. Our findings suggest that the development of policy based on a knowledge of correlates of substance use within the white community may be both inefficient and ineffective when applied to minority communities.

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