The ontology of person-centered healthcare: Theoretical essentials to reground medicine within its humanistic framework. Part I - A centered concept of personhood: Some tools to conceptualise subjectivity

2018 ◽  
Vol 6 (1) ◽  
pp. 146
Author(s):  
Thomas Frölich ◽  
F F Bevier ◽  
Alicja Babakhani ◽  
Hannah H Chisholm ◽  
Peter Henningsen ◽  
...  

To address subjectivity, as a generally rooted phenomenon, other ways of visualisation must be applied than in conventional objectivistic approaches. Using ‘trees’ as operational metaphors, as employed in Arthur Cayley’s ‘theory of the analytical forms called trees’, one rooted ‘tree’ must be set beneath the other and, if such ‘trees’ are combined, the resulting ‘forest’ is nevertheless made up of individual ‘trees’ and not of a deconstructed mix of ‘roots’, ‘branches’, ‘leaves’ or further categories, each understood as addressable both jointly and individually. The reasons for why we have chosen a graph theory and corresponding discrete mathematics as an approach and application are set out in this first of our three articles. It combines two approaches that, in combination, are quite uncommon and which are therefore not immediately familiar to all readers. But as simple as it is to imagine a tree, or a forest, it is equally simple to imagine a child blowing soap bubbles with the aid of a blow ring. A little more challenging, perhaps, is the additional idea of arranging such blow rings in series, transforming the size of the soap bubble in one ring after the other. To finally combine both pictures, the one of trees and the other of blow rings, goes beyond simple imagination, especially when we prolong the imagined blow ring becoming a tunnel, with a specific inner shape. The inner shape of the blow ring and its expansion as a tunnel are understood as determined by discrete qualities, each forming an internal continuity, depicted as a scale, with the scales combined in the form of a glyph plot. The different positions on these scales determine their length and if the endpoints of the spines are connected with an enveloping line then this corresponds to the free space left open in the tunnel to go through it. Using so many visualisation techniques at once is testing. Nevertheless, this is what we propose here and to facilitate such a visualisation within the imagination, we do it step by step. As the intended result of this ‘juggling of three balls’, as it were, we end up with a concept of how living beings elaborate their principal structure to enable controlled outside-inside communication.

1994 ◽  
Vol 68 (3) ◽  
pp. 207-210 ◽  
Author(s):  
M.Y. Manga-González ◽  
M.P. Morrondo-Pelayo

AbstractDevelopment of Neostrongylus linearis larvae was studied in the snail intermediate hosts Oestophora (Oestophora) barbula, Oestophorella buvinieri, Cepaea nemoralis and Helix (Cryptomphalus) aspersa. The molluscs of each species, all adults, were divided into groups of 40 for infection purposes. The infection doses for the first two snail species were 90 and 50 first stage larvae (L1) of N. linearis, respectively. For C. nemoralis two batches were tested: one with 200 L1 kept at 19°C and the other with 250 L1 at a temperature of 21°C. The same was done with Helix (C.) aspersa with 200 L1 at a temperature of 21°C, on the one hand and 300 L1 at 24°C on the other. One or two molluscs of each species were killed in series from the 6th day post-infection (p.i.) until the 44th. Percentage values for total larvae (1, 2 and 3) and L3 were higher with the lower dose for C. nemoralis, whilst the same was true with the higher dose in Helix (C.) aspersa. In both cases, the higher temperature appeared to contribute to cycle acceleration. Using one way analysis of variance, statistically significant differences were detected between the species of molluscs tested concerning percentages of L1 which penetrated, total larvae and L3. According to our results, the decreasing order of susceptibility of these species of molluscs as experimental intermediate hosts of N. linearis is: O. buvinieri, Oestophora (O.) barbula, C. nemoralis and Helix (C.) aspersa. It is the first time that Oestophora (O.) barbula and Oestophorella buvinieri have been named as experimental intermediate hosts of N. linearis.


Author(s):  
Stefano De Falco

A dichotomy often frequent in the context of geographic studies concerns the dualism between propagation and induction models-based phenomena, inherent in variables and factors characterizing contiguous areas, and research relating to homogeneity between geographically not closed areas. In the wake of the latter research, this contribution proposes a model that exploits the potential of graph theory for the evaluation of common dynamics relating to non-contiguous areas. The assumption underlying the model envisages configuring the reality being studied in terms of a network whose nodes and branches are respectively representative of entities distant from each other and of their related affinities. The proposed approach focuses on some Italian industrial districts. The value of the proposed approach is twofold, on the one hand regarding the specific industrial district topic with both scientific and practical implications, and on the other hand it aims to provide a method that can be replicated in similar scenarios in which it is interesting to evaluate the similarity between neighboring areas analytically.


Symmetry ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 802
Author(s):  
Martin Knor ◽  
Muhammad Imran ◽  
Muhammad Kamran Jamil ◽  
Riste Škrekovski

A graph G is called an ℓ-apex tree if there exist a vertex subset A ⊂ V ( G ) with cardinality ℓ such that G − A is a tree and there is no other subset of smaller cardinality with this property. In the paper, we investigate extremal values of several monotonic distance-based topological indices for this class of graphs, namely generalized Wiener index, and consequently for the Wiener index and the Harary index, and also for some newer indices as connective eccentricity index, generalized degree distance, and others. For the one extreme value we obtain that the extremal graph is a join of a tree and a clique. Regarding the other extreme value, which turns out to be a harder problem, we obtain results for ℓ = 1 and pose some open questions for higher ℓ. Symmetry has always played an important role in Graph Theory, in recent years, this role has increased significantly in several branches of this field, including topological indices of graphs.


Muzikologija ◽  
2020 ◽  
pp. 205-234
Author(s):  
Dragan Latincic

The text describes the application of one of the most important isometric transformations to the projected metro-rhythmic entities of individual harmonics of the spectrum. It is a direct isometry called central rotation. Central rotation conditions the hemiola structuring of the meter. Hemiolas are identified with regular and irregular geometric figures (primarily triangles) by means of a partition and the composition (index) number of a particular spectral harmonics. The partition and composition of numbers, which are dealt with in discrete mathematics, on the one hand, and, the technique of horizontal hemiolas, characteristic of the polyphony of the sub-Saharan region, on the other, served as a means of creating methods by which the isometric transformation of central rotation would be realized in (musical) time.


1975 ◽  
Vol 26 ◽  
pp. 395-407
Author(s):  
S. Henriksen

The first question to be answered, in seeking coordinate systems for geodynamics, is: what is geodynamics? The answer is, of course, that geodynamics is that part of geophysics which is concerned with movements of the Earth, as opposed to geostatics which is the physics of the stationary Earth. But as far as we know, there is no stationary Earth – epur sic monere. So geodynamics is actually coextensive with geophysics, and coordinate systems suitable for the one should be suitable for the other. At the present time, there are not many coordinate systems, if any, that can be identified with a static Earth. Certainly the only coordinate of aeronomic (atmospheric) interest is the height, and this is usually either as geodynamic height or as pressure. In oceanology, the most important coordinate is depth, and this, like heights in the atmosphere, is expressed as metric depth from mean sea level, as geodynamic depth, or as pressure. Only for the earth do we find “static” systems in use, ana even here there is real question as to whether the systems are dynamic or static. So it would seem that our answer to the question, of what kind, of coordinate systems are we seeking, must be that we are looking for the same systems as are used in geophysics, and these systems are dynamic in nature already – that is, their definition involvestime.


Author(s):  
Stefan Krause ◽  
Markus Appel

Abstract. Two experiments examined the influence of stories on recipients’ self-perceptions. Extending prior theory and research, our focus was on assimilation effects (i.e., changes in self-perception in line with a protagonist’s traits) as well as on contrast effects (i.e., changes in self-perception in contrast to a protagonist’s traits). In Experiment 1 ( N = 113), implicit and explicit conscientiousness were assessed after participants read a story about either a diligent or a negligent student. Moderation analyses showed that highly transported participants and participants with lower counterarguing scores assimilate the depicted traits of a story protagonist, as indicated by explicit, self-reported conscientiousness ratings. Participants, who were more critical toward a story (i.e., higher counterarguing) and with a lower degree of transportation, showed contrast effects. In Experiment 2 ( N = 103), we manipulated transportation and counterarguing, but we could not identify an effect on participants’ self-ascribed level of conscientiousness. A mini meta-analysis across both experiments revealed significant positive overall associations between transportation and counterarguing on the one hand and story-consistent self-reported conscientiousness on the other hand.


2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.


2017 ◽  
Vol 47 (188) ◽  
pp. 487-494
Author(s):  
Daniel Mullis

In recent years, political and social conditions have changed dramatically. Many analyses help to capture these dynamics. However, they produce political pessimism: on the one hand there is the image of regression and on the other, a direct link is made between socio-economic decline and the rise of the far-right. To counter these aspects, this article argues that current political events are to be understood less as ‘regression’ but rather as a moment of movement and the return of deep political struggles. Referring to Jacques Ranciere’s political thought, the current conditions can be captured as the ‘end of post-democracy’. This approach changes the perspective on current social dynamics in a productive way. It allows for an emphasis on movement and the recognition of the windows of opportunity for emancipatory struggles.


1996 ◽  
pp. 13-23
Author(s):  
Mykhailo Babiy

Political ideological pluralism, religious diversity are characteristic features of modern Ukrainian society. On the one hand, multiculturalism, socio-political, religious differentiation of the latter appear as important characteristics of its democracy, as a practical expression of freedom, on the other - as a factor that led to the deconsocialization of society, gave rise to "nodal points" of tension, confrontational processes, in particular, in political and religious spheres.


2003 ◽  
pp. 15-26
Author(s):  
P. Wynarczyk
Keyword(s):  
The Core ◽  

Two aspects of Schumpeter' legacy are analyzed in the article. On the one hand, he can be viewed as the custodian of the neoclassical harvest supplementing to its stock of inherited knowledge. On the other hand, the innovative character of his works is emphasized that allows to consider him a proponent of hetherodoxy. It is stressed that Schumpeter's revolutionary challenge can lead to radical changes in modern economics.


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