scholarly journals Comparison of Renal Transplantation Outcomes in Patients After Peritoneal Dialysis and Hemodialysis – A Case Control Study and Literature Review

Author(s):  
Thomas Rath ◽  
Stephan Ziefle

Author(s):  
Antoine Briantais ◽  
Julie Séguier ◽  
Benjamin De Sainte Marie ◽  
Arsène Mekinian ◽  
Cristina Belizna ◽  
...  


2019 ◽  
Vol 39 (6) ◽  
pp. 570-573
Author(s):  
Hongjian Ye ◽  
Peiyi Cao ◽  
Jianxiong Lin ◽  
Xiao Yang ◽  
Qunying Guo ◽  
...  

The long-term clinical outcomes of peritoneal dialysis (PD) for patients with lupus nephritis (LN) have not been well researched. In the present study, we investigated the long-term prognosis of a Chinese PD cohort. This was a retrospective case-control study that included LN patients receiving PD treatment for more than 90 days from January 2006 to December 2012. Non-diabetic control patients were selected using a ratio of 1:2 for age- and gender-matching. The primary outcome was all-cause mortality. Secondary outcomes included technique failure and hospitalization rate. All patients were followed up to 31 December 2017. A total of 28 LN patients on PD (89.3% female, mean age 42.2±15.8 years) and 56 controls were included. After a median follow-up period of 53.1 months, 11 LN patients died. The cumulative 1-, 3-, and 5-year patient survival rates were 92.4%, 84.7%, and 67.6% in LN patients, and 100%, 93.5%, and 82.9% in the control group, respectively ( p = 0.035). After adjusting for confounders, LN was not significantly associated with mortality (hazard ratio [HR]: 1.39, 95% confidence interval [CI]: 0.45 – 4.26); However, LN was still an independent risk factor of technique failure (HR: 2.87, 95% CI: 1.08 – 7.66). Meanwhile, the LN group had significantly higher hospitalization and infection rates. In conclusion, LN patients undergoing PD had poor patient survival and technique survival, and higher hospitalization and infection rates.



PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227870
Author(s):  
Laurisson Albuquerque da Costa ◽  
Maria Cláudia Cruz Andreoli ◽  
Aluizio Barbosa Carvalho ◽  
Sérgio Antonio Draibe ◽  
José Osmar Medina Pestana ◽  
...  


2020 ◽  
Vol 33 (9) ◽  
pp. 1116-1127
Author(s):  
Ramandeep Singh ◽  
Hessel Peters‐Sengers ◽  
Ester B.M. Remmerswaal ◽  
Unsal Yapici ◽  
Karlijn A. M .I. Pant ◽  
...  


1999 ◽  
Vol 19 (3) ◽  
pp. 248-252 ◽  
Author(s):  
James M. Zacharias ◽  
Bunny Fontaine ◽  
Adrian Fine

Objective To investigate the risk factors for the development of calciphylaxis in renal failure, a poorly understood and often fatal condition characterized by calcium deposition in tissues. Design Retrospective case-control study. Setting University hospital peritoneal dialysis center. Patients Eight continuous ambulatory peritoneal dialysis (CAPD) patients with calciphylaxis were identified in a 3-year period. We matched up to five controls for dialysis modality and length of time on dialysis with each case. Statistics Multivariate conditional logistic regression analysis for matched case-controls. Main Outcome Measures Laboratory data and demographics were collected as well as cumulative calcium and vitamin D ingestion over the year prior to disease onset. Results All the patients were female, versus only 38% (14/37) of controls ( p < 0.0001). While not statistically significant, a majority of the patients were diabetic [62.5% (5/8) vs 32% (12/37)]. Peak and average levels of serum calcium, phosphate, calcium x phosphate product, parathyroid hormone (PTH), albumin, iron, total iron-binding capacity (TIBC), and ferritin were not significantly different in cases compared with controls. The use of calcitriol alone or with calcium carbonate was not found to be a significant risk factor for the development of calciphylaxis. In a multivariate analysis, iron intake seemed to be protective, contrary to previous reports, while the use of calcium carbonate was associated with a strong trend to increased risk of calciphylaxis development (odds ratio = 1.029/g and 1.011/g calcium ingested per month, at 1 and 2 – 3 months prior to calciphylaxis development; p = 0.0556 and 0.0565, respectively). Conclusion These data, although limited by the small numbers of index cases, suggest that calcium ingestion is a risk factor for calciphylaxis. The increased use of calcium salts as a phosphate binder in recent years might explain the apparent increased incidence of calciphylaxis in our and other centers. The preponderance of female diabetics among cases reported elsewhere was confirmed in our study.





1999 ◽  
Vol 14 (12) ◽  
pp. 2937-2940 ◽  
Author(s):  
Carl Warholm ◽  
Jonas Berglund ◽  
Jan Andersson ◽  
Gunnar Tydén


2015 ◽  
Vol 47 (12) ◽  
pp. 2039-2046 ◽  
Author(s):  
Urs Benck ◽  
Peter Schnuelle ◽  
Bernd Krüger ◽  
Kai Nowak ◽  
Thomas Riester ◽  
...  




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