scholarly journals Antioxidant Status and Sex Hormones in Women with Simple Endometrial Hyperplasia

10.5772/60853 ◽  
2015 ◽  
Author(s):  
Snežana Pejić ◽  
Ana Todorović ◽  
Vesna Stojiljković ◽  
Ivan Pavlović ◽  
Ljubica Gavrilović ◽  
...  
Keyword(s):  
Sex Hormones ◽  
Antioxidant Status ◽  
Endometrial Hyperplasia

scholarly journals SEX HORMONES AND OXIDANT- ANTIOXIDANT STATUS IN POST-MENOPAUSAL WOMEN WITH CORONARY ARTERY DISEASE

2006 ◽  
Vol 35 (1) ◽  
pp. 71-99
Author(s):  
Mohamed Helaly ◽  
Eid Daoud ◽  
Ibrahtm Abdel Aal ◽  
Hosam Ghanem ◽  
Mohammed El-Arman ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Sex Hormones ◽  
Antioxidant Status ◽  
Menopausal Women ◽  
Artery Disease ◽  
Post Menopausal

scholarly journals Sesame Ingestion Affects Sex Hormones, Antioxidant Status, and Blood Lipids in Postmenopausal Women

2006 ◽  
Vol 136 (5) ◽  
pp. 1270-1275 ◽  
Author(s):  
Wen-Huey Wu ◽  
Yu-Ping Kang ◽  
Nai-Hung Wang ◽  
Hei-Jen Jou ◽  
Tzong-An Wang
Keyword(s):  
Postmenopausal Women ◽  
Sex Hormones ◽  
Antioxidant Status ◽  
Blood Lipids

Expression of HOXA10 in Endometrial Hyperplasia and Adenocarcinoma and Regulation by Sex Hormones In Vitro

2011 ◽  
Vol 21 (5) ◽  
pp. 800-805 ◽  
Author(s):  
Gang Zhong ◽  
Yan Wang ◽  
Xuemei Liu
Keyword(s):  
Sex Hormones ◽  
Endometrial Hyperplasia

scholarly journals Antioxidant status in women with uterine leiomyoma: relation with sex hormones

2015 ◽  
Vol 87 (3) ◽  
pp. 1771-1782 ◽  
Author(s):  
SNEŽANA PEJIĆ ◽  
ANA TODOROVIĆ ◽  
VESNA STOJILJKOVIĆ ◽  
LJUBICA GAVRILOVIĆ ◽  
NATAŠA POPOVIĆ ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Menstrual Cycle ◽  
Glutathione Peroxidase ◽  
Glutathione Reductase ◽  
Sex Hormones ◽  
Antioxidant Status ◽  
Uterine Leiomyoma ◽  
Lipid Hydroperoxides ◽  
Smooth Muscle Tissue ◽  
Significant Difference

ABSTRACTUterine leiomyomas are benign soft-tissues tumors that arise from uterine smooth muscle tissue. Etiopathogenesis of leiomyomas is not well understood. We aimed to examine whether antioxidant enzyme activities and lipid hydroperoxides level in patients with leiomyoma are influenced by changes in sex hormones and gonadotropins (estradiol (E2), progesterone, FSH, and LH) during menstrual cycle and in postmenopause. The material consisted of blood and uterine tissue specimens. Hormone concentrations were determined and assays for superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activities and lipid hydroperoxides concentration were performed. In blood of examined women, a significant difference in catalase, glutathione peroxidase and glutathione reductase activity was recorded among the phases. There was also a positive correlation between the estradiol/progesterone concentration and the catalase activity. Progesterone negatively correlated with lipid hydroperoxides level. In myoma tissue, we recorded a phase-related difference in lipid hydroperoxides level and activities of superoxide dismutase, glutathione peroxidase activities, and glutathione reductase. Negative correlation was observed between FSH and glutathione peroxidase. The results suggest that antioxidant status in patients with uterine leiomyoma is influenced by the changes in sex hormones during the menstrual cycle and in postmenopause, indicating a role of the observed relationship in the leiomyoma etiology.

Sex Hormones, Mood, Mental State and Memory

2001 ◽  
Vol 12 (6) ◽  
pp. 475-475
Keyword(s):  
Sex Hormones ◽  
Mental State

Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis

2020 ◽  
pp. 1-8
Author(s):  
Hasan Haci Yeter ◽  
Berfu Korucu ◽  
Elif Burcu Bali ◽  
Ulver Derici
Keyword(s):  
Oxidative Stress ◽  
Vitamin D ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Total Oxidant Status ◽  
Vitamin D Analog ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

Abstract. Background: The pathophysiological basis of chronic kidney disease and its complications, including cardiovascular disease, are associated with chronic inflammation and oxidative stress. We investigated the effects of active vitamin D (calcitriol) and synthetic vitamin D analog (paricalcitol) on oxidative stress in hemodialysis patients. Methods: This cross-sectional study was composed of 83 patients with a minimum hemodialysis vintage of one year. Patients with a history of any infection, malignancy, and chronic inflammatory disease were excluded. Oxidative markers (total oxidant and antioxidant status) and inflammation markers (C-reactive protein and interleukin-6) were analyzed. Results: A total of 47% (39/83) patients were using active or analog vitamin D. Total antioxidant status was significantly higher in patients with using active or analog vitamin D than those who did not use (p = 0.006). Whereas, total oxidant status and oxidative stress index were significantly higher in patients with not using vitamin D when compared with the patients who were using vitamin D preparation (p = 0.005 and p = 0.004, respectively). On the other hand, total antioxidant status, total oxidant status, and oxidative stress index were similar between patients who used active vitamin D or vitamin D analog (p = 0.6; p = 0.4 and p = 0.7, respectively). Conclusion: The use of active or selective vitamin D analog in these patients decreases total oxidant status and increases total antioxidant status. Also, paricalcitol is as effective as calcitriol in decreasing total oxidant status and increasing total antioxidant status in patients with chronic kidney disease.

Pro-oxidant effects of a high α-tocopherol dose on kidney antioxidant biomarkers and histopathological aspects

2017 ◽  
Vol 87 (3-4) ◽  
pp. 179-190
Author(s):  
Amel Kanane ◽  
Fayrouz Rouaki ◽  
Mohamed Brahim Errahmani ◽  
Abdenour Laraba ◽  
Hayet Mesbah ◽  
...  
Keyword(s):  
Sunflower Oil ◽  
Antioxidant Status ◽  
Basal Diet ◽  
Inflammatory Cells ◽  
Significant Rise ◽  
Control Group ◽  
Histopathological Changes ◽  
Group 5 ◽  
Oxidant Effect ◽  
Higher Doses

Abstract. The aim of this study is to evaluate the effect of α-tocopherol supplementation at two doses (600 and 1200 mg × kg–1) on kidney antioxidant status and the histopathological changes in Wistar rats after 12 weeks of exposure at different diets. Forty rats has been divided into 4 groups of 10 rats each, the control group received basal diet with 5 % fresh sunflower oil (FSO), the second group: 5 % oxidized sunflower oil (OSO), the third group: 5 % OSO supplemented with 600 mg × kg–1 α-tocopherol and the fourth group: 5 % OSO supplemented with 1200 mg × kg–1 α-tocopherol. In OSO groups, the results showed highly significant increases of LPO (from 31.3 ± 0.9 to 53.8 ± 1.2 nmol of MDA formed/min/mg protein, p < 0.0001) with a significant decrease (p < = 0.001) of the antioxidant enzymatic activities (CAT, SOD, GPX, GR and G6PDH), body weight (339 ± 9 to 290 ± 3 g) and α-tocopherol levels (13.6 ± 0.6 to 6.5 ± 0.4 μg/mg protein). In OSO groups with 600 mg × kg–1 α-tocopherol, an antioxidant effect was found, reflected by a return of the parameters to values similar to those of the control group. However, higher doses of α-tocopherol (1200 mg × kg–1) induced a depletion of antioxidant status, α-tocopherol levels (6.0 ± 0.3 μg/mg protein, p < 0.001) and a very highly significant rise (p < 0.0001) of LPO content (54.86 ± 0.01 nmol of MDA formed/min/mg protein). The kidney tissues also showed changes in glomerular, severe inflammatory cells infiltration, and formation of novel vessels. So, we can conclude that the oxidative stress is attenuated by a moderate administration of 600 mg × kg–1 α-tocopherol, while a pro-oxidant effect occurs at 1200 mg × kg–1 α-tocopherol.

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