scholarly journals Non-Invasive Prediction of Gastroesophageal Varices in Patients with Portal Hypertension

2021 ◽  
Author(s):  
Ran Wang ◽  
Xiaozhong Guo ◽  
Xingshun Qi
Keyword(s):  
Computed Tomography ◽  
Portal Hypertension ◽  
Gold Standard ◽  
Serum Markers ◽  
Common Complication ◽  
Gold Standard Method ◽  
Gastroesophageal Varices ◽  
Non Invasive ◽  
Invasive Method ◽  
Worse Prognosis

Gastroesophageal varices are the most common complication of portal hypertension and associated with a worse prognosis. Endoscopy is the gold standard method to diagnose gastroesophageal varices. However, endoscopy is an invasive method with potential complications and is not well adhered by patients. Non-invasive methods, including serum markers or scores, computed tomography, ultrasonographic, and elastography-based methods, have been explored for the diagnosis of gastroesophageal varices. In the current chapter, we will briefly review non-invasive methods for the prediction of gastroesophageal varices.

Correlation of Portal and Splenic Vein Diameter with Presence and Size of Esophageal and Gastric Varices in Liver Cirrhosis Patients on MDCT

2020 ◽  
Vol 10 (2) ◽  
pp. 2-8
Author(s):  
Anamika Jha ◽  
Yusra Ali ◽  
Ghanshyam Gurung ◽  
Ranjit Kumar Chaudhary ◽  
Akhilesh Kumar Kasyap
Keyword(s):  
Computed Tomography ◽  
Portal Hypertension ◽  
Splenic Vein ◽  
Gastric Varices ◽  
Inclusion Criteria ◽  
Left Gastric Vein ◽  
Gastroesophageal Varices ◽  
Non Invasive ◽  
Vein Diameter ◽  
Ethical Clearance

Introduction: Variceal formation depends upon the pattern of dilatation of the portal and various splanchnic veins in patients with cirrhotic liver and portal hypertension. Multidetector Computed Tomography (MDCT) may be helpful in the evaluation of such gastroesophageal varices and predicting their risk of haemorrhage.Methods: After obtaining ethical clearance and consent, 50 patients meeting the inclusion criteria were included and MDCT obtained. The diameters of the portal vein (PV), splenic vein (SV) and left gastric vein (LGV) were measured and originating vein of LGV determined. Pattern, location and diameter of varix was evaluated. Association between the diameters of the originating vein and the grade and pattern of the esophagael and gastric fundic varices was determined.Results: Of the 50 patients, 41 had gastroesophageal (GE) varices equal to or larger than 1mm with 34% having high-risk varices. The SV was predominantly the originating vein of the LGV. Cutoff SV diameter of 7.75mm and LGV diameter of 5.75mm had a sensitivity of 77.8% with a specificity of 73.2% and 75.6% respectively for the presence of varices.Conclusions: In our study, EV and GEV was more common and mostly supplied by LGV while isolated gastric fundic varices were supplied by non LGV veins only. The diameters of SV and LGV were associated with the presence and grade of esophageal and gastric fundic varices. MDCT is an important non-invasive modality in patients with portal hypertension and should be used for diagnosis, risk stratification and monitoring of varices.

scholarly journals miRNAs and lncRNAs: Potential Non-Invasive Biomarkers for Endometriosis

Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1662
Author(s):  
Ioana Maria Maier ◽  
Adrian Cornel Maier
Keyword(s):  
Clinical Trials ◽  
Minimally Invasive ◽  
Gold Standard ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Diagnostic Methods ◽  
Non Invasive ◽  
Invasive Method ◽  
Minimally Invasive Methods ◽  
Exploratory Laparoscopy

Many studies have tried to understand the mechanism of endometriosis and its manner of manifestation. However, the only method of diagnosis considered as the gold standard in endometriosis is an invasive method called exploratory laparoscopy. Hence, there is a need to identify non-invasive or minimally invasive methods to minimize patients’ suffering, thus increasing their addressability at the earliest possible staging of the disease, and to diagnose this condition as soon as possible. miRNAs (microRNAs) and lncRNAs (long-noncoding RNAs) are potential non-invasive diagnostic methods for endometriosis. Multiple clinical trials indicate that miRNA can be used as a non-invasive method in the diagnosis and differentiation of endometriosis stages.

scholarly journals VIRTUAL BRONCHOSCOPY OF MULTISPIRAL COMPUTED TOMOGRAPHY WITH TRAUMATIC INJURIES OF THE MAIN BRONCHUS

2019 ◽  
pp. 63-67
Author(s):  
P. M. Kotlyarov ◽  
N. V. Chernichenko ◽  
V. P. Kharchenko
Keyword(s):  
Computed Tomography ◽  
Main Bronchus ◽  
Traumatic Rupture ◽  
Virtual Bronchoscopy ◽  
Traumatic Injuries ◽  
Traumatic Lesion ◽  
Non Invasive ◽  
Invasive Method ◽  
Bone Structures

The aim of the study was to evaluate the role of virtual bronchoscopy (VB) in traumatic rupture of the main bronchus Material and methods. Тhe data of virtual bronchoscopy of multispiral computed tomography (MSCT) with multiplanar and 3D reconstructions of 10 patients with traumatic separation of the main bronchus were analyzed. MSCT was carried out by the computer tomograph AquilionONE (320-slice) according to the previously described technique. Results of the study. VB MSCT allowed to determine the presence of a complete or partial rupture of the main bronchus, its distance to the bifurcation of the trachea, the state of the collapsed lung, the presence of fluid in the hemithorax, secondary changes in the bone structures of the chest. The World Bank played an important role in monitoring the adequacy of reconstructive measures on the damaged bronchus, excluding the occurrence of postoperative stenosis. The conclusion. Virtual bronchoscopy of multispiral computed tomography with the capabilities of multiplanar and volumetric reconstructions, postprocessing image processing is an optimal non-invasive method for determining the traumatic lesion of the main bronchi and monitoring the success of the reconstructive surgical manual.

scholarly journals Progress of non-invasive diagnostic of liver fibrosis: review of modern laboratory methods

2020 ◽  
pp. 224-232
Author(s):  
E. A. Kulebina ◽  
A. N. Surkov
Keyword(s):  
Liver Fibrosis ◽  
Gold Standard ◽  
Diagnostic Techniques ◽  
Serum Markers ◽  
Diagnostic Systems ◽  
Non Invasive ◽  
Type Iv ◽  
Acid Type ◽  
Experimental Laboratory ◽  
Invasive Techniques

Fibrosis and cirrhosis are traditionally diagnosed by making a biopsy. However, in recent decades, scientists around the world have shown that the accepted “gold standard of diagnosis” – morphological assessment of biopsy – has a number of limitations. The search for non-invasive techniques to diagnose fibrosis has led to the development of many scales using laboratory indices. Non-invasive diagnostic techniques are safer for the patient than liver biopsy. In addition, they can be repeated in a dynamic to assess the condition of the liver over time. Most currently available non-invasive diagnostic techniques are considerably cheaper than the accepted “gold standard”. Their practical use is increasing every year, and in a number of countries the frequency of liver biopsies in viral hepatitis B and C is steadily decreasing due to the development of serum and imaging diagnostic systems. Recent studies show that the assessment of the degree of fibrosis by non-invasive methods is as accurate as a morphological study. In recent years, a number of serum markers have been considered as non-invasive diagnostics of the stages of liver fibrosis, among which the largest number of studies are devoted to hyaluronic acid, type IV collagen, and their combination with various common laboratory tests. The latest non-invasive techniques will make a significant paradigm shift in the evaluation of liver fibrosis in the near future. In this review we have analyzed widely used as well as experimental laboratory techniques used in the diagnosis of liver fibrosis.

Use of computed tomography as a non-invasive method for diagnosing cephenemyiosis in roe deer (Capreolus capreolus)

2014 ◽  
Vol 29 (1) ◽  
pp. 110-113 ◽  
Author(s):  
L. E. FIDALGO ◽  
A. M. LÓPEZ-BECEIRO ◽  
M. VILA-PASTOR ◽  
C. MART ÍNEZ-CARRASCO ◽  
J. D. BARREIRO-VÁZQUEZ ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Roe Deer ◽  
Capreolus Capreolus ◽  
Non Invasive ◽  
Invasive Method

scholarly journals The practical use of computed tomography in evaluation of shell lesions in six loggerhead turtles (Caretta caretta)

2016 ◽  
Vol 61 (No. 7) ◽  
pp. 394-398 ◽  
Author(s):  
F. Spadola ◽  
G. Barillaro ◽  
M. Morici ◽  
A. Nocera ◽  
Z. Knotek
Keyword(s):  
Computed Tomography ◽  
Spinal Cord ◽  
Physical Examination ◽  
Lumbar Vertebra ◽  
Caretta Caretta ◽  
Tube Insertion ◽  
Computed Tomographic ◽  
Non Invasive ◽  
Loggerhead Turtles ◽  
Invasive Method

Six adult loggerhead turtles were found stranded and were rescued near Sicily within a period of 12 months. Macroscopically apparent lesions of the shell were present. After thorough physical examination, ketamine-dexmedetomidine-atipamezole induction and tracheal tube insertion all six patients underwent computed tomographic examination under inhalant anaesthesia with isoflurane. A vertebral lesion at the level of the 3<sup>rd</sup> thoracic-lumbar vertebra with vertebral lamina and the vertebral body being involved without compression of the spinal cord, a vertebral lesion at the level of the 7<sup>th</sup> thoracic-lumbar vertebra and a vertebral lesion at the level of the 8<sup>th</sup> thoracic-lumbar vertebra were recorded in the first female. Loss of the shell near the left carapace-plastron bridge, with massive haemorrhage and compression of organs were present in the second female. The remaining four turtles had only superficial lesions with no involvement of bones and organs of the coelom. Computed tomography was proved to be a valuable non-invasive method for clinical examination of stranded sea turtles.

scholarly journals Ultrasound - first imaging modality in the detection of parathyroid adenomas

2008 ◽  
Vol 12 (3) ◽  
pp. 64 ◽  
Author(s):  
R Ahmed ◽  
N Khan ◽  
S Ellemdin ◽  
K Gayaparsad
Keyword(s):  
Nuclear Medicine ◽  
High Resolution ◽  
Gold Standard ◽  
Imaging Modality ◽  
Non Invasive ◽  
Highly Sensitive ◽  
Parathyroid Adenomas ◽  
Thyroid Adenomas ◽  
Invasive Method ◽  
Ultrasound Features

Abstract We present a series of 12 patients in whom the typical ultrasound features of parathyroid adenomas were accurately demonstrated. High resolution ultrasound [in experienced hands] is a highly sensitive accurate, safe and non invasive method of localizing parathyroid adenomas especially in patients with typically located glands and an absence of thyroid pathology. Our aim was to compare ultrasound with nuclear medicine as an imaging gold standard in patients with thyroid adenomas.

scholarly journals Assessing GastroPanel serum markers as a non-invasive method for the diagnosis of atrophic gastritis and <i>Helicobacter pylori</i> infection

2012 ◽  
Vol 02 (03) ◽  
pp. 113-118 ◽  
Author(s):  
Dominique Noah Noah ◽  
Marie Claire Okomo Assoumou ◽  
Servais Albert Fiacre Eloumou Bagnaka ◽  
Guy Pascal Ngaba ◽  
Ivo Ebule Alonge ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Atrophic Gastritis ◽  
Serum Markers ◽  
Non Invasive ◽  
Invasive Method

scholarly journals Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study

Sensors ◽  
2019 ◽  
Vol 19 (16) ◽  
pp. 3467 ◽  
Author(s):  
Vratislav Fabian ◽  
Lukas Matera ◽  
Kristyna Bayerova ◽  
Jan Havlik ◽  
Vaclav Kremen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Gold Standard ◽  
Pulse Wave ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Gold Standard Method ◽  
Non Invasive ◽  
Occlusion Cuff

Cardiovascular diseases are one of most frequent cause of morbidity and mortality in the world. There is an emerging need for integrated, non-invasive, and easy-to-use clinical tools to assess accurately cardiovascular system primarily in the preventative medicine. We present a novel design for a non-invasive pulse wave velocity (PWV) assessment method integrated in a single brachial blood pressure monitor allowing for up to 100 times more sensitive recording of the pressure pulsations based on a brachial occlusion-cuff (suprasystolic) principle. The monitor prototype with built-in proprietary method was validated with a gold standard reference technique SphygmoCor VX device. The blood pressure and PWV were assessed on twenty-five healthy individuals (9 women, age (37 ± 13) years) in a supine position at rest by a brachial cuff blood pressure monitor prototype, and immediately re-tested using a gold standard method. PWV using our BP monitor was (6.67 ± 0.96) m/s compared to PWV determined by SphygmoCor VX (6.15 ± 1.01) m/s. The correlation between methods using a Pearson’s correlation coefficient was r = 0.88 (p < 0.001). The study demonstrates the feasibility of using a single brachial cuff build-in technique for the assessment of the arterial stiffness from a single ambulatory blood pressure assessment.

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