scholarly journals Post COVID-19 Conditions and the Cardiovascular System

2021 ◽  
Author(s):  
Iana Simova ◽  
Denislava Hristova ◽  
Hristina Tzanovska ◽  
Denis Nikolov ◽  
Diliana Iakova ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Personal Experience ◽  
Signs And Symptoms ◽  
Limb Ischemia ◽  
Cardiovascular Complications ◽  
Medical Attention ◽  
Acute Limb Ischemia ◽  
Coronary Syndrome ◽  
Campaign Life ◽  
Rhythm Disorder

One out of four patients affected by COVID-19 will experience persistent (>3-4 weeks) signs and symptoms (Post COVID-19 conditions or Post-Acute Sequelae of SARS-CoV-2 – PASC) and this fact will have a major significance for the healthcare and economic systems in the upcoming years. The cardiovascular system is one of the key targets for the Post COVID-19 syndrome, given the pathogenesis of the virus and prevalence of ACE-2 receptors. According to our initial personal experience via the campaign “Life after COVID” of the Bulgarian Cardiac Institute, a substantial proportion of patients having suffered from COVID-19 develop long-term cardiovascular consequences. They could range from rhythm disorder and blood pressure variation, through impairment of myocardial mechanics and heart failure, and to acute vascular manifestations of Post COVID-19 conditions, such as acute coronary syndrome, acute pulmonary embolism, and acute limb ischemia. These cardiovascular complications require special and dedicated medical attention, and we could share our personal experience on the matter.

scholarly journals Cardiovascular system and coronavirus disease-2019 (COVID-19): mutual injuries and unexpected outcomes

2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Eman Sobh ◽  
Muhammad Saad Reihan ◽  
Tamer M. S. Hifnawy ◽  
Khloud Gamal Abdelsalam ◽  
Sohaila Sabry Awad ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Poor Prognosis ◽  
Clinical Decision ◽  
Cardiovascular Complications ◽  
Main Body ◽  
Negative Consequences ◽  
Coronary Syndrome ◽  
System A ◽  
High Index Of Suspicion ◽  
Unexpected Outcomes

Abstract Background Cardiovascular system involvement in coronavirus disease-2019 (COVID-19) has gained great interest in the scientific community. Main body Several studies reported increased morbidity and mortality among COVID-19 patients who had comorbidities, especially cardiovascular diseases like hypertension and acute coronary syndrome (ACS). COVID-19 may be associated with cardiovascular complications as arrhythmia, myocarditis, and thromboembolic events. We aimed to illustrate the interactions of COVID-19 disease and the cardiovascular system and the consequences on clinical decision as well as public health. Conclusions COVID-19 has negative consequences on the cardiovascular system. A high index of suspicion should be present to avoid poor prognosis of those presenting with unusual presentation.

scholarly journals Exercise Training and Cardiac Rehabilitation in COVID-19 Patients with Cardiovascular Complications: State of Art

Life ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 259
Author(s):  
Mariaconsiglia Calabrese ◽  
Marina Garofano ◽  
Roberta Palumbo ◽  
Paola Di Pietro ◽  
Carmine Izzo ◽  
...  
Keyword(s):  
Exercise Training ◽  
Cardiac Rehabilitation ◽  
Cardiovascular System ◽  
Patient Monitoring ◽  
Scientific Evidence ◽  
Cardiovascular Complications ◽  
Angiotensin Converting Enzyme 2 ◽  
Coronary Syndrome ◽  
Cardiovascular Damage ◽  
Include Heart Failure

Recent scientific literature has investigated the cardiovascular implications of COVID-19. The mechanisms of cardiovascular damage seem to involve the protein angiotensin-converting enzyme 2 (ACE2), to which severe acute respiratory syndrome (SARS) coronavirus-2 (CoV-2) binds to penetrate cells and other mechanisms, most of which are still under study. Cardiovascular sequelae of COVID-19 include heart failure, cardiomyopathy, acute coronary syndrome, arrhythmias, and venous thromboembolism. This article aims to collect scientific evidence by exploiting PubMed, Scopus, and Pedro databases to highlight the cardiovascular complications of COVID-19 and to define the physiotherapy treatment recommended for these patients. Exercise training (ET), an important part of cardiac rehabilitation, is a powerful tool in physiotherapy, capable of inducing significant changes in the cardiovascular system and functional in the recovery of endothelial dysfunction and for the containment of thromboembolic complications. In conclusion, due to the wide variety of possible exercise programs that can be obtained by combining intensity, duration, and speed in various ways, and by adjusting the program based on continuous patient monitoring, exercise training is well suited to the treatment of post-COVID patients with an impaired cardiovascular system of various degrees.

scholarly journals CARDIOONCOLOGY: CHEMOTHERAPY DRUGS AND RADIATION THERAPY IMPACT ON CARDIOVASCULAR SYSTEM

2016 ◽  
Vol 7 (4) ◽  
pp. 41-48
Author(s):  
D P Doundoua ◽  
A V Staferov ◽  
A V Sorokin ◽  
A G Kedrova
Keyword(s):  
Heart Failure ◽  
Acute Coronary Syndrome ◽  
Radiation Therapy ◽  
Cardiovascular System ◽  
Limb Ischemia ◽  
Anticancer Therapy ◽  
Vascular Toxicity ◽  
Chemotherapy Drugs ◽  
Coronary Syndrome ◽  
Definition Of

Anticancer therapy can cause angina pectoris, acute coronary syndrome, stroke, critical limb ischemia, arterial hypertension, arrhythmias and heart failure. The new specialization in cardiology, called cardiooncology, exploring the complications of cardiovascular system, arising during the treatment of cancer. The first part of the review, based on the publications of the last decades, is dedicated to the definition of cardiooncology, mechanisms of cardiac and vascular toxicity with a number of anticancer drugs affecting the cardiovascular system.

scholarly journals COVID-19 and the Cardiovascular System: How the First PostModern Pandemic ‘Weakened’ our Hearts

2020 ◽  
Vol 3 ◽  
pp. e15
Author(s):  
Syeda Tasneem Towhid ◽  
◽  
Nadira Naznin Rakhi ◽  
ASM Shamsul Arefin ◽  
Otun Saha ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Cardiac Injury ◽  
Age Groups ◽  
Signs And Symptoms ◽  
Holistic Approach ◽  
Cardiovascular Complications ◽  
Cardiac Complications ◽  
Cardiovascular Damage ◽  
Preventative Measures ◽  
Life Threatening

The global spread of SARS-CoV-2 with its diverse signs and symptoms manifested in COVID-19 patients across different age groups and geographic locations perplexed the clinicians and public health experts. Emerging variants of SARS-CoV-2 through continuous mutation with a limited arsenal of treatment made the study of viral pathogenesis and factors associated with disease outcomes in a holistic approach inevitable, among which pre-existing cardiovascular complications were found to be significantly associated with adverse outcome of COVID-19. In addition, COVID-19 has already been reported to cause cardiac injury and different cardiovascular complications in patients irrespective of preexisting cardiovascular complications, which highlights the importance of recognizing the complications at the onset, although these arising complications might be an indirect effect of SARS-CoV-2 induced cytokine storm or hypoxia rather the virus itself. Also, the drugs used for the clinical management of the patients may have an impact on the induced cardiac complications. Thus, the effect of SARS-CoV-2 on the cardiovascular system needs to be investigated in order to predict the clinical outcome and to devise a proper treatment strategy. Besides, the interaction of vaccines or therapeutics to be approved with the cardiovascular system needs to be evaluated to avoid confounding effects leading to cardiovascular complications followed by post-approval retraction. However, potential biomarkers (eg. troponin, D-dimers, fibrin) associated with cardiac injury may be potentially useful in predicting life-threatening conditions early enough to save lives. In conclusion, this review summarizes the molecular pathogenesis of cardiovascular damage caused by SARS-CoV-2 in COVID-19 patients, as well as prescribed treatment and preventative measures.

scholarly journals An uncommon case of acute lower limb ischemia

2019 ◽  
Vol 13 (3) ◽  
pp. 185-186
Author(s):  
Maria Viviana Carlino ◽  
Paola Ieranò ◽  
Mario Venafro ◽  
Claudia Sara Cimmino ◽  
Costantino Mancusi ◽  
...  
Keyword(s):  
Emergency Department ◽  
Lower Limb ◽  
Plaque Rupture ◽  
Abdominal Mass ◽  
Signs And Symptoms ◽  
Limb Ischemia ◽  
Acute Limb Ischemia ◽  
Computed Tomographic ◽  
Lower Limb Pain ◽  
The Impact

We describe a case of a 76-year-old woman who presented to the Emergency Department with right lower limb pain after a fall. One hour after the admission to the Emergency Department, the patient presented all the signs and symptoms of acute limb ischemia. The patient underwent contrast-enhanced computed tomographic scan of abdomen and right lower limb that showed a large abdominal lesion suggestive of ovarian cancer compressing the right common iliac artery and a visible thrombus and ruptured plaque in this artery. We hypothesized that the acute limb ischemia caused by thrombosis in situ arose from acute plaque rupture probably due to the impact of the large abdominal mass on the artery during patient’s fall.

GLYCEMIC STATUS AND SHORT TERM OUTCOME IN PATIENTS WITH DIABETES MELLITUS ADMITTED WITH ACUTE MACROVASCULAR COMPLICATION IN A TERTIARY CARE HOSPITAL IN INDIA

2021 ◽  
pp. 31-33
Author(s):  
Soumyajit Mukherjee ◽  
Prabir Kumar Kundu ◽  
Indira Maisnam ◽  
Apurba Kumar Mukherjee
Keyword(s):  
Diabetes Mellitus ◽  
Acute Coronary Syndrome ◽  
Cerebrovascular Accident ◽  
Limb Ischemia ◽  
Diabetic Patients ◽  
Acute Limb Ischemia ◽  
Care Hospital ◽  
Medical College ◽  
Coronary Syndrome ◽  
Hospitalized Patient

Introduction: Diabetes is a global endemic with rapidly increasing prevalence in both developing and developed countries. Over the past two decades the prevalence of diabetes has risen from an estimated 30 million cases in 1985 to 415 million in 2017. Aims & objectives: To study HbA1c and other biochemical & clinical parameters of acute ischemic cerebrovascular accident, acute coronary syndrome and acute limb ischemia in diabetic patients. Specific objectives: · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute ischemic cerebrovascular accident. · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute coronary syndrome · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute limb ischemia · To study correlation between HbA1C and 72 hours mortality of patients with acute macrovascular events among diabetics. Materials & methods: Department of general medicine, R.G.Kar Medical College and Hospital.Cases were selected from medicine inpatients department of R.G.Kar Medical College and Hospital. 1st July, 2018-30th June 2019. This is an observational prospective study Conclusion: In our study we found that higher HbA1C is associated with statistically signicant increase in 72 hour mortality in patients with acute ischemic stroke and trend of increased mortality (though not statistically signicant) in patients (p=0.0002 & 0.056 respectively)

Acute limb ischemia in a patient with pre-fibrotic myelofibrosis complicated by heparin-induced thrombocytopenia and thrombosis – case report and systematic review of dabigatran use

VASA ◽  
2020 ◽  
pp. 1-6 ◽  
Author(s):  
Marina Di Pilla ◽  
Stefano Barco ◽  
Clara Sacco ◽  
Giovanni Barosi ◽  
Corrado Lodigiani
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Lower Limb ◽  
Limb Ischemia ◽  
Acute Limb Ischemia ◽  
Review Of The Literature ◽  
Heparin Induced Thrombocytopenia ◽  
Lower Limb Ischemia ◽  
Vein Thrombosis ◽  
Left Lower Limb

Summary: A 49-year-old man was diagnosed with pre-fibrotic myelofibrosis after acute left lower-limb ischemia requiring amputation and portal vein thrombosis. After surgery he developed heparin-induced thrombocytopenia (HIT) with venous thromboembolism, successfully treated with argatroban followed by dabigatran. Our systematic review of the literature supports the use of dabigatran for suspected HIT.

Endovascular treatment of acute limb ischemia caused by an intravascularly deployed bioabsorbable plug of a vascular closure device

VASA ◽  
2013 ◽  
Vol 42 (2) ◽  
pp. 144-148 ◽  
Author(s):  
Daniel Maxien ◽  
Barbara Behrends ◽  
Karla M. Eberhardt ◽  
Tobias Saam ◽  
Sven F. Thieme ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Limb Ischemia ◽  
Closure Device ◽  
Acute Limb Ischemia ◽  
Vascular Closure Device
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