scholarly journals High Prevalence of Drug-Resistant Gram-Negative Bacteria: A Hospital-Based Cross-Sectional Study in Tehran, in 2017

2020 ◽  
Vol 14 (6) ◽  
Author(s):  
Fahimeh Hadavand ◽  
Latif Gachkar ◽  
Maryam Amini
Thorax ◽  
2018 ◽  
Vol 74 (1) ◽  
pp. 87-90 ◽  
Author(s):  
Michelle E Wood ◽  
Rebecca E Stockwell ◽  
Graham R Johnson ◽  
Kay A Ramsay ◽  
Laura J Sherrard ◽  
...  

The airborne route is a potential pathway in the person-to-person transmission of bacterial strains among cystic fibrosis (CF) populations. In this cross-sectional study, we investigate the physical properties and survival of common non-Pseudomonas aeruginosa CF pathogens generated during coughing. We conclude that Gram-negative bacteria and Staphylococcus aureus are aerosolised during coughing, can travel up to 4 m and remain viable within droplet nuclei for up to 45 min. These results suggest that airborne person-to-person transmission is plausible for the CF pathogens we measured.


The Lancet ◽  
2019 ◽  
Vol 393 ◽  
pp. S21
Author(s):  
Abdelraouf A Elmanama ◽  
Mariam R Al-Reefi ◽  
Madleen A Shamali ◽  
Haya I Hemaid

Author(s):  
Timileyin Y Adediran ◽  
Kinjal N Sethuraman ◽  
Surbhi Leekha ◽  
Mary-Claire Roghmann

Abstract In this cross-sectional study, we examined the relationship between resident level of care in the nursing home and colonization with resistant gram-negative bacteria. Residential-care residents were more likely to be colonized with resistant gram-negative bacteria than were postacute care residents (odds ratio, 2.3; 95% confidence interval, 1.40–3.80; P < .001).


2020 ◽  
Vol 36 (1) ◽  
pp. 67-72
Author(s):  
Oumer Sada Muhammed ◽  
Getachew Alemkere ◽  
Beshir Bedru Nasir

Sepsis is one of the commonest reasons of neonatal deaths. It is accountable for about 30 - 50% of the whole baby deaths in the developing  ountries. The current study aimed to assess drug susceptibility patterns of isolates from cases of neonatal sepsis. Institution based cross-sectional study was conducted among 132 neonates admitted to Yekatit 12 teaching hospital with the diagnosis of sepsis and who had a positive result for culture and sensitivity test. Data was collected through medical chart review using data abstraction tool. The data was analyzed using excel and reported using descriptive tables. Gram-negative bacteria were the commonest organisms identified 124 (93.9%), followed by gram-positive isolates (6.1%). Klebsiella (87.9%) was the predominant gram-negative bacteria. Of the gram-positive organisms, coagulase negative staphylococci (3.03%) were the commonest pathogen, followed by Staphylococcus aureus (2.27%). Among the gram-negative isolates, overall sensitivity was high to meropenem (96.0%), amikacin (94.3%) and amoxicillin + clavulanate (74.2%) but sensitivity was very low to ampicillin (2.7%), and amoxicillin (7.3%).Generally, the isolated pathogens were resistant to commonly used antibiotics in the study setting and resistance of gram-positive pathogens  Against penicillins and cephalosporins was also high. Hence, rational and tailored antibiotic use based on the susceptibility data is recommended and regular antibiotic susceptibility surveillance should be conducted. Keywords: neonatal sepsis, cross-sectional study, antibiotics, culture, sensitivity, resistance


2012 ◽  
pp. 129-134
Author(s):  
Thi Lan Tran ◽  
Thi Huong Le ◽  
Xuan Ninh Nguyen

Objectives: Assess the nutritional status, worm infection status and some related factors among children aged 12-36 months of Dakrong district, Quang Tri province. Subject and method: A cross sectional study was carried out in 2010, in 680 children aged 12-36 months in 4 communes of Dakrong district, Quang Tri province. Results: The malnutrition rate was 55.0% for underweight, 66.5% for stunting and 16.2% for wasting. The prevalence of malnutrition increases by age group. The prevalence of worm infection was 31.6%, the highest prevalence was belong to Ascaris infection (24.6%), followed by Hookworm and Trichuris (6.5% and 6.2%, respectively). The prevalence of worm infection among children under two is very high (27.0%). The prevalence of worm infection was distributed quite equally between the malnutrition children group and normal children group. Recommendation: Early deworming forchildren from 12 months should be considered as important strategy against the malnutrition of children in Dakrong district, Quang Tri province


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
A. Calas ◽  
N. Zemali ◽  
G. Camuset ◽  
J. Jaubert ◽  
R. Manaquin ◽  
...  

Abstract Background Recommendations for sexually transmitted infection (STI) screening vary significantly across countries. This study evaluated the prevalence of urogenital and extragenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG) in patients visiting a French STI clinic in the Indian Ocean region to determine whether current STI screening practices should be updated. Methods This cross-sectional study examined all patients who visited the STI clinic between 2014 and 2015. Triplex polymerase chain reaction screening for CT, NG, and MG was performed on urine, vaginal, pharyngeal, and anal specimens (FTD Urethritis Basic Kit, Fast Track Diagnostics, Luxembourg). Results Of the 851 patients enrolled in the study, 367 were women (367/851, 43.2%) and 484 were men (484/851, 56.0%). Overall, 826 urogenital specimens (826/851, 97.1%), 606 pharyngeal specimens (606/851, 71.2%), and 127 anal specimens (127/851, 14.9%) were taken from enrolled patients. The prevalence of urogenital CT and MG was high in women ≤25 years (19/186, 10.21%; 5/186, 2.69%) and in men who have sex with women ≤30 years (16/212, 7.54%; 5/212, 2.36%). Among patients with urogenital CT infection, 13.7% (7/51) had urethritis. All patients with urogenital MG infection were asymptomatic. Men who have sex with men had a high prevalence of pharyngeal CT (2/45, 4.44%) and NG (3/44, 6.81%) and a high prevalence of anal CT (2/27, 7.41%), NG (2/27, 7.40%), and MG (1/27, 3.70%). After excluding patients with concomitant urogenital infection, extragenital infections with at least 1 of the 3 pathogens were found in 20 swabs (20/91, 21.9%) taken from 16 patients (16/81, 19.7%), all of them asymptomatic. Conclusions Routine multisite screening for CT, NG, and MG should be performed to mitigate the transmission of STIs in high-risk sexually active populations.


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