scholarly journals Depression Severity and Sexual Satisfaction in Fertile and Infertile Women in Iran: A Population-Based Case-Control Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Katayoun Bakhtiar ◽  
Arash Ardalan ◽  
Farzad Ebrahimzadeh ◽  
Mohammad Almasian ◽  
Fatemeh Bastami

Background: Depression and sexual dissatisfaction are among the most common psychological factors caused by infertility. Infertility is an essential topic in the Iranian culture, and many studies have already investigated it. Objectives: This study aimed to compare the depression severity and sexual dissatisfaction between fertile and infertile women in Iran. Methods: This case-control study enrolled 180 infertile women and 540 fertile women in 2019. The participants were selected through multistage stratified and cluster sampling methods. For each infertile woman, three fertile women were randomly selected. The data collection instruments consisted of a demographic form, the Depression Inventory Scale (Second Edition), and the Linda Berg Sexual Satisfaction Questionnaire. The multivariate marginal model and SPSS version 21 were used for data analysis at a significance level of 0.05. Results: After adjustment for confounding variables, the marginal model showed that the odds of depression increased by approximately 21.305 times among cases compared to controls (OR = 21.305, 95% CI = 14.75 - 32.021, P < 0.001). This model also found that by moderating the effects of confounding variables, infertility increased the odds of low sexual satisfaction by approximately 15.560 times (OR = 15.560, 95% CI = 5.089 - 47.571, P < 0.001). The chi-square test showed a significant relationship between infertility treatment and depression severity in infertile women (P = 0.001). Conclusions: The overall depression severity and sexual dissatisfaction were higher in the infertile group than in the fertile one. Most cases of severe depression were observed in IVF clinics with higher depression levels. The study may help reveal infertility's psychological and social aspects in Iran.

2020 ◽  
Author(s):  
Katayoun Bakhtiar ◽  
Arash Ardalan ◽  
Farzad Ebrahimzadeh ◽  
Fatemeh Bastami ◽  
Mohammad Almasian

Abstract Background: Depression and sexual dissatisfaction are among the most common psychological factors caused by infertility. Infertility is an important topic in Iranian culture and many studies have already targeted them. The aim of this study was to compare the severity of both depression and sexual dissatisfaction between fertile and infertile groups of women in Iran.Methods: A number of 180 infertile and 540 fertile women participated in this case-control study. The cases were selected through a combination of multistage stratified and cluster sampling method. For each infertile woman, three fertile women were randomly selected. Data gathering instrument consisted of demographic variables, Depression Inventory Scale, Second Edition, and the Linda Berg Sexual Satisfaction Questionnaire. The multivariate marginal model and SPSS 21 software were used for data analyses with a significance level of 0.05.Results: After adjusting for the effect of confounding variables, the marginal model showed the odds of depression increased by approximately 21.305 times among cases compared to control subjects (OR = 21.305, 95% CI for OR:14.75-32.021, P < 0.001). This model also found that by moderating the effect of confounding variables, infertility increased the odds of low sexual satisfaction by approximately 15.560 times (OR = 15.560, 95% CI for OR = 5.089–47.571, p < 0.001). Chi-square test (Monte Carlo Simulation) showed a significant relationship between infertility treatment and severity of depression in infertile group of women (P = 0.001). Severe cases of depression were mostly seen among women who received IVF treatment.Conclusion: The overall severity of depression and sexual dissatisfaction were higher in infertile group than that of fertile one. Also, most cases of severe depression were seen in IVF clinics, which may boost their depression. The results of this study may help reveal the psychological and social aspects of infertility in, Iran.


2016 ◽  
Vol 9 (1) ◽  
pp. 244
Author(s):  
Ameneh Safarzadeh ◽  
Hossein Ansari ◽  
Anisseh Arbabisarjou ◽  
Shahindokht Navvabi Rigi ◽  
Saeedeh Rigi

INTRODUCTION: Secondary infertility can cause some problems for the couples involved, particularly the women. It is supposed that the life style could influence the fertility status of the couples. This study was aimed to comparison the life style between secondary infertile and fertile women.MATERIALS AND METHODS: In this case-control study, 125 secondary infertile women as case group and 140 fertile women as control group were investigated in 2015. The subjects were selected from the fertility clinics and private office of the gynecologists in Zahedan, southeast of Iran. The data were collected using a structured questionnaire including reproductive history, socio-demographic variables, physical activity and Pittsburgh sleep quality. To analyze the data were used Chi-square and multiple logistic regression with Hosmer&Lemeshow method.RESULTS: By adjusting for potential confounders the secondary infertile women were more likely to have had higher BMI and be overweight (OR=2.89, 95%CI: 1.15-10.1) than fertile women. The sedentary and low sleep quality were significantly more common in infertile women than fertile women (OR=2.37, 95%CI: 1.005-9.7 and OR=2.92, 95% CI: 1.6-9.3, respectively). Also the chance of nutritional related disease among cases was more that controls (P<0.05). CONCLUSION: As life style related factors were associated with some reproductive variables in this study, thus it could be concluded that the life style and nutritional status not only influence the obstetric events, but directly effect on fertility via another paths. However, decreasing weight and increasing physical activity, improvement of sleep quality are all likely to decrease secondary infertility in women.


2020 ◽  
Vol 20 (3) ◽  
pp. 1241-1249
Author(s):  
Mostafa Ahmadi ◽  
Mahbobeh Faramarzi ◽  
Zahra Basirat ◽  
Farzan Kheirkhah ◽  
Mohammad Chehrazi ◽  
...  

Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common causes of infertility in women. Objective: The current study investigated mental and personality disorders in infertile women with and without PCOS. Methods: This case-control study evaluated 400 infertile women who referred to the Infertility Center in Babol city (North of Iran). Participants were categorized into the case group (201 PCOS) and the control group (199 without PCOS). All of the participants completed the Millon Clinical Multi-axial Inventory-III (MCMI-III). Results: The mean scores for clinical personality patterns were significantly higher for six personality disorders (schiz- oid, avoidant, antisocial, depressive, sadistic, and negativistic) and for three classes of severe personality disorder patterns (schizotypal, borderline, and paranoid) in infertile women with PCOS than in women without PCOS. The mean scores for eight clinical disorders (somatoform, manic disorder, dysthymia, alcohol-dependence, drug-dependence, post-trauma stress disorder, major depression, and delusion disorder) were also higher in infertile women with PCOS than in women without PCOS. Conclusion: The scores of many mental and personality disorders are higher in infertile women with PCOS than in women without PCOS. Thus, clinicians should prioritize recognizing and treating psychological problems of infertile women with PCOS. Keywords: Polycystic ovarian syndrome; infertility; personality disorders.


2020 ◽  
Author(s):  
Xiaoying Lai ◽  
Shiyu Zhou ◽  
Zewei Lin ◽  
Chuanjie Yan ◽  
Hong Zhu ◽  
...  

Abstract Background Chronic Kidney Disease (CKD) has become a global public health problem. Identifying the risk factors of CKD can provide strategies for the prevention of CKD. Studies showed that lifestyles play an important role in CKD, but the relationship between them remained unclear. Thus we aimed to explore the association of lifestyle behaviors (the dietary habits especially) with CKD. Methods A 1:1 matched case-control study including 1414 participates from the HUIQIAO health database system from Jan. 2015 to Dec. 2018 was conducted. Our main outcome measure was the diagnose of CKD, and exposures were lifestyle behaviors measured by a questionnaire. The anthropometric characteristics were included as confounding variables. Results We used conditional logistics regression to assess the odds ratios (ORs) and adjusted ORs for the risk factors. With the assumption of missing at random (MAR) pattern, the missing values of confounding variables and exposures were handled by multiple imputation. We found that lifestyle behaviors regarding skipping breakfast ≥ 3 times per week (1.672, 95% CI, 1.086–2.574), sleep efficiency ≤ 75% (1.633, 95% CI, 1.195–2.232), consuming baked food frequently (1.683, 95% CI, 1.163–2.434), proper intake of oil (0.789, 95% CI, 0.624–0.996), proper intake of aquatic product (0.732, 95% CI, 0.567–0.944), proper intake of soybean and nuts (0.625, 95% CI, 0.447–0.873) were associated with CKD. Conclusion These results suggest that moderate intake of soybean, nuts, and aquatic product, control oil intake, having breakfast at least 4 times per week, maintaining good sleep efficiency, and consuming less baked foods may contribute to prevent the development of CKD. Trial registration: This study is registered at http://www.chictr.org.cn (ChiCTR2000031864).


2016 ◽  
Vol 13 (6) ◽  
pp. 4721-4728 ◽  
Author(s):  
CHRYSOULA MARGIOULA SIARKOU ◽  
YANNIS PRAPAS ◽  
STAMATIOS PETOUSIS ◽  
STEFANOS MILIAS ◽  
KONSTANTINOS RAVANOS ◽  
...  

2001 ◽  
Vol 16 (10) ◽  
pp. 2050-2055 ◽  
Author(s):  
A. Pauwels ◽  
P.J.C. Schepens ◽  
T. D'Hooghe ◽  
L. Delbeke ◽  
M. Dhont ◽  
...  

1999 ◽  
Vol 82 (07) ◽  
pp. 14-18 ◽  
Author(s):  
Francesco Zito ◽  
Augusto Di Castelnuovo ◽  
Andria D’Orazio ◽  
Riccardo Negrini ◽  
Domenico De Lucia ◽  
...  

SummaryThe contribution of Helicobacter pylori (HP) infection to the risk of myocardial infarction was evaluated. The role of fibrinogen and its genetic control as a possibile mechanism by which HP may influence myocardial infarction risk was explored in this context. A case-control study was performed in 101 patients with myocardial infarction and in 101 controls.HP infection was associated with an increased risk of myocardial infarction independently for confounding variables (OR 4.1, CI95: 1.8-9.4). HP infection was significantly associated with higher levels of fibrinogen, both in cases and in controls. Furthermore, there was an additive effect of HP infection and B2 allele of BclI fibrinogen poly-morphism in increasing fibrinogen levels. HP infection showed a stronger effect on the risk of myocardial infarction in B2 allele carriers (OR 7.6, CI95: 1.8-31.6) as compared to subjects carrying the B1B1 genotype (OR 3.3, CI95: 1.2-9.2).We showed that a previous HP infection is a risk factor for myocardial infarction. An increase in fibrinogen levels is a possible mechanism by which HP may act. Concomitant conditions, like a genetic predisposition in increasing fibrinogen levels, seem to further increase the effect of HP on myocardial infarction risk.


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