scholarly journals Epidemiology of Acute Rotavirus Diarrhea Among Hospitalized Children Under Five Years of Age in Hefei, China, During 2015 - 2018

2020 ◽  
Vol 13 (7) ◽  
Author(s):  
Liping Yuan ◽  
Gillian Gianna Anne Lum ◽  
Junmei Zhao ◽  
Wenya Li
Keyword(s):  
Hospital Admission ◽  
Anhui Province ◽  
Viral Gastroenteritis ◽  
Hospitalized Children ◽  
Rotavirus Infection ◽  
Children Under Five ◽  
Rotavirus A ◽  
Under Five ◽  
Rotavirus Diarrhea ◽  
Acute Viral Gastroenteritis

Background: Rotavirus infection is still the leading cause of acute viral gastroenteritis in children under five years of age worldwide. It is also a serious public health concern in China. Objectives: This study aimed to obtain information about rotavirus diarrhea among hospitalized children in Hefei City, Anhui Province, China, in recent years. Methods: We conducted a retrospective study over four years (2015 - 2018) examining hospital admission records of rotavirus infections at the First Affiliated Hospital of Anhui Medical University in Hefei City of Anhui Province, China. Results: A total of 1,095 cases with acute viral gastroenteritis requiring hospital admission from January 2015 to December 2018 were analyzed. Among them, 276 cases were positive for rotavirus A infection, accounting for 25.21% of the total number of children suffering from acute diarrhea. The detection rate of rotavirus A was the highest in children aged 1 - 2 years. The peak month for rotavirus infection during 2015 - 2018 was December and January. The hospitalized children with rotavirus infection showed dehydration, electrolyte disorder, liver function abnormality, and myocardial enzyme abnormality. Conclusions: Rotavirus is still the first pathogen of acute viral diarrhea in children in Hefei, especially children < 2 years of age, which highlights the need for widespread rotavirus immunization in young children.

scholarly journals Epidemiology of Rotavirus diarrhea in children under five: A hospital-based surveillance in Jakarta

2011 ◽  
Vol 51 (3) ◽  
pp. 138 ◽  
Author(s):  
Muzal Kadim ◽  
Yati Soenarto ◽  
Badriul Hegar ◽  
Agus Firmansyah
Keyword(s):  
Acute Diarrhea ◽  
Seasonal Pattern ◽  
Hospitalized Children ◽  
Rota Virus ◽  
Prospective Surveillance ◽  
Children Under Five ◽  
Rotavirus A ◽  
Under Five ◽  
Clear Seasonal Pattern ◽  
Rotavirus Diarrhea

Background Rotavirus is still a major cause of acute diarrhea in children around the world, both in developed and developingcountries. WHO Surveillance from 2001 to 2008 showed that in children under five years of age treated for acute diarrhea, on average 40% of cases were caused by rotavirus. A previous study in Indonesia showed that the incidence of rotavirus diarrhea in children ranged from 20%􀁑60% of diarrhea cases. However, there have been few studies identifying the genotypes of rotavirus strains in Indonesia. This infonnation is indispensable for manufacturing vaccines.Objective To examine the epidemiology of rotavirus diarrhea, including genotypes and clinical characteristics, in children under five years who were hospitalized in Jakarta.Methods This study was a prospective surveillance conducted at Cipto Mangunkusumo Hospital, Jakarta from January to December 2007 investigating hospitalized children under five years of age who suffered from acute diarrhea.Results Ninety􀁑nine patients joined the study. The incidence of rotavirus infection in this study was 67%. The youngest was 2months of age and the oldest 54 months of age, Mth an average age of 13.6 months. As much as 92% of rota virus diarrhea was found in subjects aged 3􀁑23 months, Mth a peak age of 12􀁑23 months. Nutritional status, degree of dehydration, bloating, fever, blood in stool, and mucus in the feces were not significantly different between rotavirus and non􀁑rotavirus diarrhea. Vomiting tended to be more frequently experienced by children Mth rotavirus diarrhea than those with non􀁑rotavirus (88% vs. 67%). There was no clear, seasonal pattern for rotavirus diarrhea. Most G genotypes in this study were G1 (35%), G9 (12.5%), G2 (7.5%) and the majority of P genotypes were P6 (52.5%), P8 (17.5%) and P4 (10%).Conclusions The incidence of rotavirus diarrhea in hospitalized children under five years of age in Jakarta was 67%, with apredominance ofG1, G9 and G2 genotypes. 

Rotavirus infection among hospitalized children under five years of age with acute watery diarrhea in Sri Lanka

Vaccine ◽  
2018 ◽  
Vol 36 (51) ◽  
pp. 7846-7850 ◽  
Author(s):  
Paba Palihawadana ◽  
Gagandeep Kang ◽  
Janakan Navaratnasingam ◽  
Geethani Galagoda ◽  
Janaki Abeynayake ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Watery Diarrhea ◽  
Hospitalized Children ◽  
Rotavirus Infection ◽  
Children Under Five ◽  
Under Five ◽  
Acute Watery Diarrhea

Characterization of astrovirus-associated gastroenteritis in hospitalized children under five years of age

2017 ◽  
Vol 53 ◽  
pp. 94-99 ◽  
Author(s):  
Hassan Zaraket ◽  
Hadi Abou-El-Hassan ◽  
Khalil Kreidieh ◽  
Nadia Soudani ◽  
Zainab Ali ◽  
...  
Keyword(s):  
Hospitalized Children ◽  
Children Under Five ◽  
Under Five

scholarly journals Rotavirus Diarrhoea among Children under Five Years in a Tertiary Level Government of Rajasthan

2017 ◽  
Vol 36 (3) ◽  
pp. 273-276
Author(s):  
Abhijit Ari ◽  
Ruchi Chaudhary ◽  
S.D. Sharma
Keyword(s):  
Acute Diarrhea ◽  
Enzyme Linked Immunosorbent Assay ◽  
Tertiary Level ◽  
Hospitalized Children ◽  
Under Five ◽  
Stool Samples ◽  
Rotavirus Diarrhea ◽  
Age Range ◽  
Elisa Result ◽  
Level Government

Introduction: Rotavirus is the leading cause of severe, dehydrating diarrhoea in young children globally. Studies indicate that rotavirus causes approximately 40 percent of childhood diarrhoea hospitalization worldwide and around 39 percent in India in less than 5 years of age. This study aimed to estimate the prevalence of rotavirus diarrhea among hospitalized children aged under five years.Materials and Method: Stool samples were collected from children who fall within the age range of 0-5 years with acute diarrhea and samples are tested for rotavirus by the enzyme linked immunosorbent assay (ELISA).Result: Out of 349 samples, 104(29.8%) cases were positive for rotavirus by ELISA. Therefore the prevalence of rotavirus infection among hospitalized patient under this study was 29.8%.Conclusion: Rotavirus is an important cause of diarrhea in hospitalized children.J Nepal Paediatr Soc 2016;36(3):273-276

Etiology of Non-Rotaviral Diarrhea in Hospitalized Children Under Five Years of Age

2020 ◽  
Vol 87 (7) ◽  
pp. 571-572
Author(s):  
Itta Krishna Chaaithanya ◽  
Debdutta Bhattacharya ◽  
Tanmayi Patil ◽  
Kirti Vittal Ghargi ◽  
Shanta Kalal ◽  
...  
Keyword(s):  
Hospitalized Children ◽  
Children Under Five ◽  
Under Five

scholarly journals Molecular Epidemiology and Clinical Risk Factors of Rotavirus Diarrhea: Single Center 5-Year Experience

2021 ◽  
Author(s):  
Ekin Soydan ◽  
İlknur Çağla ◽  
Mine Düzgol ◽  
Hurşit Apa ◽  
İlker Devrim ◽  
...  
Keyword(s):  
Acute Gastroenteritis ◽  
Laboratory Data ◽  
Clinical Findings ◽  
Study Data ◽  
Children Under Five ◽  
Under Five ◽  
Common Causes ◽  
Training And Research ◽  
Rotavirus Diarrhea

Objective: Acute gastroenteritis due to the rotavirus is one of the common causes of morbidity and mortality in children under five years of age. The objective of this study was to evaluate the epidemiological, clinical, and laboratory data of rotavirus diarrhea in hospitalized children under five years of age. Methods: All children between one month and 60 months old ages who were hospitalized in Health Sciences University Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital during September 2013 to August 2017 and diagnosed as acute gastroenteritis with rotavirus antigen test positive in feces were included in the current study. Data of the patients were collected retrospectively from medical records. Results: A total of 100 patients were evaluated.The median age of the patients was 13 months (IQR 5-45 months) and 54 patients were male and 46 were female.The highest hospitalization rate was in December, followed by November, and in October. The most common type of G9P (8) serotype was detected in rotavirus serotype analysis by PCR. Breastfeeding infants had milder clinic findings in comparison to the older ones. It was found that clinical findings were milder and Vesicari score was lower in infants who had breast milk. Vesikari score was found to be high in children with severe clinical findings. Conclusion: Rotavirus infection is important for all ages.In case of fever, increased numbers of vomiting and diarrhea, and higher Vesikari system scores may be associated with the severe clinical forms. Determination of rotavirus serotypes and clinical monitoring of genotypic changes are required.

scholarly journals High prevalence of circulating DS-1-like human rotavirus A and genotype diversity in children with acute gastroenteritis in Thailand from 2016 to 2019

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e10954
Author(s):  
Siripat Pasittungkul ◽  
Fajar Budi Lestari ◽  
Jiratchaya Puenpa ◽  
Watchaporn Chuchaona ◽  
Nawarat Posuwan ◽  
...  
Keyword(s):  
Acute Gastroenteritis ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Viral Gastroenteritis ◽  
Seasonal Incidence ◽  
Rotavirus Infection ◽  
Rotavirus A ◽  
Human Rotavirus ◽  
Genotype Diversity ◽  
Stool Samples

Background Human rotavirus A (RVA) infection is the primary cause of acute gastroenteritis (AGE) in infants and young children worldwide, especially in children under 5 years of age and is a major public health problem causing severe diarrhea in children in Thailand. This study aimed to investigate the prevalence, genotype diversity, and molecular characterization of rotavirus infection circulating in children under 15 years of age diagnosed with AGE in Thailand from January 2016 to December 2019. Methods A total of 2,001 stool samples were collected from children with gastroenteritis (neonates to children <15 years of age) and tested for RVA by real-time polymerase chain reaction (RT-PCR). Amplified products were sequenced and submitted to an online genotyping tool for analysis. Results Overall, 301 (15.0%) stool samples were positive for RVA. RVA occurred most frequently among children aged 0-24 months. The seasonal incidence of rotavirus infection occurred typically in Thailand during the winter months (December-March). The G3P[8] genotype was identified as the most prevalent genotype (33.2%, 100/301), followed by G8P[8] (10.6%, 32/301), G9P[8] (6.3%, 19/301), G2P[4] (6.0%, 18/301), and G1P[6] (5.3%, 16/301). Uncommon G and P combinations such as G9P[4], G2P[8], G3P[4] and G3P[9] were also detected at low frequencies. In terms of genetic backbone, the unusual DS-1-like G3P[8] was the most frequently detected (28.2%, 85/301), and the phylogenetic analysis demonstrated high nucleotide identity with unusual DS-1-like G3P[8] detected in Thailand and several countries. Conclusions A genetic association between RVA isolates from Thailand and other countries ought to be investigated given the local and global dissemination of rotavirus as it is crucial for controlling viral gastroenteritis, and implications for the national vaccination programs.

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