scholarly journals Epidemiology of Rotavirus diarrhea in children under five: A hospital-based surveillance in Jakarta

2011 ◽  
Vol 51 (3) ◽  
pp. 138 ◽  
Author(s):  
Muzal Kadim ◽  
Yati Soenarto ◽  
Badriul Hegar ◽  
Agus Firmansyah
Keyword(s):  
Acute Diarrhea ◽  
Seasonal Pattern ◽  
Hospitalized Children ◽  
Rota Virus ◽  
Prospective Surveillance ◽  
Children Under Five ◽  
Rotavirus A ◽  
Under Five ◽  
Clear Seasonal Pattern ◽  
Rotavirus Diarrhea

Background Rotavirus is still a major cause of acute diarrhea in children around the world, both in developed and developingcountries. WHO Surveillance from 2001 to 2008 showed that in children under five years of age treated for acute diarrhea, on average 40% of cases were caused by rotavirus. A previous study in Indonesia showed that the incidence of rotavirus diarrhea in children ranged from 20%􀁑60% of diarrhea cases. However, there have been few studies identifying the genotypes of rotavirus strains in Indonesia. This infonnation is indispensable for manufacturing vaccines.Objective To examine the epidemiology of rotavirus diarrhea, including genotypes and clinical characteristics, in children under five years who were hospitalized in Jakarta.Methods This study was a prospective surveillance conducted at Cipto Mangunkusumo Hospital, Jakarta from January to December 2007 investigating hospitalized children under five years of age who suffered from acute diarrhea.Results Ninety􀁑nine patients joined the study. The incidence of rotavirus infection in this study was 67%. The youngest was 2months of age and the oldest 54 months of age, Mth an average age of 13.6 months. As much as 92% of rota virus diarrhea was found in subjects aged 3􀁑23 months, Mth a peak age of 12􀁑23 months. Nutritional status, degree of dehydration, bloating, fever, blood in stool, and mucus in the feces were not significantly different between rotavirus and non􀁑rotavirus diarrhea. Vomiting tended to be more frequently experienced by children Mth rotavirus diarrhea than those with non􀁑rotavirus (88% vs. 67%). There was no clear, seasonal pattern for rotavirus diarrhea. Most G genotypes in this study were G1 (35%), G9 (12.5%), G2 (7.5%) and the majority of P genotypes were P6 (52.5%), P8 (17.5%) and P4 (10%).Conclusions The incidence of rotavirus diarrhea in hospitalized children under five years of age in Jakarta was 67%, with apredominance ofG1, G9 and G2 genotypes. 

scholarly journals Epidemiology of Acute Rotavirus Diarrhea Among Hospitalized Children Under Five Years of Age in Hefei, China, During 2015 - 2018

2020 ◽  
Vol 13 (7) ◽  
Author(s):  
Liping Yuan ◽  
Gillian Gianna Anne Lum ◽  
Junmei Zhao ◽  
Wenya Li
Keyword(s):  
Hospital Admission ◽  
Anhui Province ◽  
Viral Gastroenteritis ◽  
Hospitalized Children ◽  
Rotavirus Infection ◽  
Children Under Five ◽  
Rotavirus A ◽  
Under Five ◽  
Rotavirus Diarrhea ◽  
Acute Viral Gastroenteritis

Background: Rotavirus infection is still the leading cause of acute viral gastroenteritis in children under five years of age worldwide. It is also a serious public health concern in China. Objectives: This study aimed to obtain information about rotavirus diarrhea among hospitalized children in Hefei City, Anhui Province, China, in recent years. Methods: We conducted a retrospective study over four years (2015 - 2018) examining hospital admission records of rotavirus infections at the First Affiliated Hospital of Anhui Medical University in Hefei City of Anhui Province, China. Results: A total of 1,095 cases with acute viral gastroenteritis requiring hospital admission from January 2015 to December 2018 were analyzed. Among them, 276 cases were positive for rotavirus A infection, accounting for 25.21% of the total number of children suffering from acute diarrhea. The detection rate of rotavirus A was the highest in children aged 1 - 2 years. The peak month for rotavirus infection during 2015 - 2018 was December and January. The hospitalized children with rotavirus infection showed dehydration, electrolyte disorder, liver function abnormality, and myocardial enzyme abnormality. Conclusions: Rotavirus is still the first pathogen of acute viral diarrhea in children in Hefei, especially children < 2 years of age, which highlights the need for widespread rotavirus immunization in young children.

PO-0225 Sociodemographic Pattern And Seasonal Pattern Of Rota Virus Infection In Children Under Five Years Old

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A318.1-A318
Author(s):  
J Cheriathu ◽  
L Jenny John ◽  
E Ignatius Dsouza ◽  
M Shamseldeen
Keyword(s):  
Virus Infection ◽  
Seasonal Pattern ◽  
Rota Virus ◽  
Children Under Five ◽  
Under Five

scholarly journals Rotavirus Diarrhoea among Children under Five Years in a Tertiary Level Government of Rajasthan

2017 ◽  
Vol 36 (3) ◽  
pp. 273-276
Author(s):  
Abhijit Ari ◽  
Ruchi Chaudhary ◽  
S.D. Sharma
Keyword(s):  
Acute Diarrhea ◽  
Enzyme Linked Immunosorbent Assay ◽  
Tertiary Level ◽  
Hospitalized Children ◽  
Under Five ◽  
Stool Samples ◽  
Rotavirus Diarrhea ◽  
Age Range ◽  
Elisa Result ◽  
Level Government

Introduction: Rotavirus is the leading cause of severe, dehydrating diarrhoea in young children globally. Studies indicate that rotavirus causes approximately 40 percent of childhood diarrhoea hospitalization worldwide and around 39 percent in India in less than 5 years of age. This study aimed to estimate the prevalence of rotavirus diarrhea among hospitalized children aged under five years.Materials and Method: Stool samples were collected from children who fall within the age range of 0-5 years with acute diarrhea and samples are tested for rotavirus by the enzyme linked immunosorbent assay (ELISA).Result: Out of 349 samples, 104(29.8%) cases were positive for rotavirus by ELISA. Therefore the prevalence of rotavirus infection among hospitalized patient under this study was 29.8%.Conclusion: Rotavirus is an important cause of diarrhea in hospitalized children.J Nepal Paediatr Soc 2016;36(3):273-276

scholarly journals Molecular characterization of norovirus infection responsible for acute diarrhea in Congolese hospitalized children under five years old in Brazzaville, Republic of Congo

2019 ◽  
Vol 88 ◽  
pp. 41-48 ◽  
Author(s):  
Vivaldie Mikounou Louya ◽  
Christevy Vouvoungui ◽  
Félix Koukouikila-Koussounda ◽  
Francisco Veas ◽  
Simon Charle Kobawila ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Acute Diarrhea ◽  
Hospitalized Children ◽  
Republic Of Congo ◽  
Children Under Five ◽  
Under Five

scholarly journals Prevalence and clinical characteristics of rotavirus diarrhea in Mataram, Lombok, Indonesia

2016 ◽  
Vol 56 (2) ◽  
pp. 118 ◽  
Author(s):  
Wayan Sulaksmana Sandhi Parwata ◽  
Wayan Sukardi ◽  
Abdul Wahab ◽  
Yati Soenarto
Keyword(s):  
General Hospital ◽  
Acute Diarrhea ◽  
Clinical Symptoms ◽  
Watery Diarrhea ◽  
Surveillance Network ◽  
Cross Sectional ◽  
Children Under Five ◽  
Under Five ◽  
Rotavirus Diarrhea ◽  
Rotavirus Infections

diarrhea and dehydration among children aged <5 years in developed and developing countries, including Indonesia. There have been few studies on the prevalence of rotavirus diarrhea in Mataram.Objective To determine the prevalence and characteristics of rotavirus diarrhea in children under five years of age with acute diarrhea in Mataram.Methods A cross sectional study using the WHO Generic Protocol for Rotavirus Surveillance was conducted in the Nusa Tenggara Barat (NTB) General Hospital, Mataram, as part of a multicenter study by the Indonesian Rotavirus Surveillance Network (IRSN) for children under five years of age. Subjects were diagnosed with rotavirus diarrhea based on stool sample examinations, using RT-PCR for genotyping. They were admitted to the Pediatrics Ward of the NTB Provincial General Hospital from January to December 2010.Results Of 329 children admitted with acute diarrhea, 210 (63.8%) had rotavirus positive stool specimens. For the year 2010, the highest incidence of rotavirus infection was in the month of January (86.4%). Rotavirus infections were found in children less than 2 years of age (65.4%), with the highest prevalence in the age group of 6 to 23 months (68.5%). In addition to clinical symptoms of watery diarrhea, there was a significantly greater percentage of vomiting in rotaviral vs. non-rotaviral diarrhea (67.7% vs. 32.3%, respectively; P<0.05). The majority of G and P genotypes found were G1 (86%), G2 (12%), P[8] (66%), P[4] (12.8%), and P[6] (8%).Conclusion Rotavirus infections are the most common cause of acute diarrhea in children aged <2 years in Mataram, Indonesia.

CLINICAL AND PARACLINICAL CHARACTERISTITICS OF ROTAVIRUS DIARRHEA IN CHILDREN LESS THAN 5 YEARS OLD IN PEDIATRIC DEPARTMENT OF BINH DINH GENERAL HOSPITAL

2013 ◽  
pp. 50-56
Author(s):  
Quoc Tinh Nguyen ◽  
Thi Cu Nguyen
Keyword(s):  
General Hospital ◽  
Acute Diarrhea ◽  
White Blood Cells ◽  
Blood Calcium ◽  
Pediatric Department ◽  
Rotavirus A ◽  
Initial Symptoms ◽  
Stool Specimens ◽  
The Mean ◽  
Rotavirus Diarrhea

Background: Diarrhea is a leading cause of morbidity and mortality in children in developing countries. Rotavirus is the most important factor cause of severe diarrhea and mortality in children, especially under 2 years. Objective: To study Clinical and paraclinical characteristitics of rotavirus diarrhea in children less than 5 years old in the Pediatric Department of Binh Dinh General Hospital. Methods: Cross observational study, 417 children from 2 months to 5 years old who were hospitalized for acute diarrhea without blood in stool in Pediatric Department of Binh Dinh general hospital, from 15/3/2012 to 14/3/2013. There were 228 patients with rotavirus - positive stool specimens and 189 patients with rotavirus - negative stool specimens. Tested for rotavirus A classification by agglutination techniques. Results: Percentage of Rotavirus diarrhea in children <5 years was 54.7%. The mean age of rotavirus diarrhea was 14.83 ± 9.08 tháng months. Ages with the highest cases of rotavirus diarrhea are 2 - 12 months: 48.2%. Rotavirrus diarrhea is experienced in every month but, the highest prevalence is experienced in the spring - summer) with 71,5%. Clinical characteristitics of rotavirus diarrhea: Vomit presents in 91,7% of cases. 32.9% of the initial symptoms of the disease is vomiting. Mean number of vomiting episodes per day: 7 ± 3.57 times, significantly higher compared with non-rotavirus acute diarrhea (p <0,01). Mean number of bowel movement per day: 10.61±4.18 times, mean duration of diarrhea: 6.66 ± 2.52 days. Younger children have higher frequency and duration of diarrhea compared to older children. Paraclinical characteristitics of rotavirus diarrhea: the mean number leukocyte: 9.74 ±3.61 (x 109/l). 2.2% with low blood sodium status; 8.8% with reduction in serum potassium concentration. 26.3% with low blood calcium and glucose status. Laboratory characteristics of stool: 8.8% with white blood cells in stool, 41.7% with carbohydrate in stool. Conclusion: Rotavirus accounting for 54.7% of the causes of diarrhea in children. Rotavirus diarrhea is experienced throughout the year but the highest prevalence is in the spring-summer. Prominent symptoms of the disease are vomiting and watery stool. Children <24 months experience higher frequency and duration of diarrhea compared to older age groups. Key words: Diarrhea, Rotavirus.

scholarly journals Prevalence of acute diarrhea and associated factors among children under five in semi-urban areas of northeastern Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tarikuwa Natnael ◽  
Mistir Lingerew ◽  
Metadel Adane
Keyword(s):  
Acute Diarrhea ◽  
Urban Areas ◽  
Odds Ratio ◽  
Associated Factors ◽  
Multivariable Analysis ◽  
Water Sources ◽  
Children Under Five ◽  
Under Five ◽  
Under Five Children ◽  
Study Participants

Abstract Background Diarrheal disease is still one of the most common causes of mortality and morbidity in children under five in developing countries, including Ethiopia. Lack of specific data on the prevalence of acute diarrhea and associated factors among under-five children in the semi-urban areas of Gelsha, found in northeastern Ethiopia’s South Wollo zone, remains a major gap. Therefore, this study was designed to provide data that is important for proper planning of intervention measures to reduce the problem in this area. Methods A community-based cross-sectional study was conducted among 340 systematically selected children under five in semi-urban areas of Gelsha from January to March 2019. The data was collected using a structured questionnaire and an observational checklist. Bivariable (crude odds ratio [COR]) and multivariable analysis (adjusted odds ratio [AOR]) were employed using binary logistic regression model with 95% CI (confidence interval). Variables with a p-value < 0.05 from the multivariable analysis were declared as factors significantly associated with acute diarrhea. Result The prevalence of acute diarrhea among children under five in the study area was 11% (95%CI: 7.8–14.3%). About two-thirds (63.60%) of study participants used water from improved sources. About half (54.90%) of study participants practiced poor handwashing and 45.10% practiced good handwashing. We found that factors significantly associated with acute diarrhea were a child’s age of 12–23 months (AOR = 4.68, 95% CI: 1.45–1.50), the presence of two or more under-five children in the house (AOR = 2.84, 95% CI: 1.19–6.81), unimproved water sources (AOR = 2.97, 95% CI: 1.28–6.87) and presence of feces around the pit hole/slab/floor of the latrine (AOR = 3.34, 95% CI: 1.34–8.31). Conclusion The prevalence of acute diarrhea among children under five was relatively high. To reduce the problem, various prevention strategies are essential, such as the provision of health education to mothers/caregivers that focuses on keeping sanitation facilities clean and child care, and construction of improved water sources. Furthermore, implementing a strong health extension program, advocating an open defecation-free environment, and practicing a community-led total sanitation and hygiene approach might be helpful to sustainably reduce childhood diarrhea.

Relative Efficacy of Probiotics Compared with Standard Therapy for Diarrhea Treatment in Children Under Five Years of Age: A Meta-Analysis Evidence from Developing Countries

2020 ◽  
Author(s):  
Nurul Aini Suria Saputri ◽  
◽  
Tri Nugraha Susilawati ◽  
Vitri Widyaningsih ◽  
◽  
...  
Keyword(s):  
Developing Countries ◽  
Acute Diarrhea ◽  
Standard Therapy ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Gastrointestinal Diseases ◽  
Relative Efficacy ◽  
Children Under Five ◽  
Under Five ◽  
Review Manager

ABSTRACT Background: Probiotics have been widely studied in a variety of gastrointestinal diseases. There is high-quality evidence that probiotics are effective for acute infectious diarrhea. This study aimed to examine the relative efficacy of probiotics compared with standard therapy for diarrhea treatment in children under five using meta-analysis. Subjects and Method: A meta-analysis was carried out using systematic PRISMA guidelines. The review process begins with searching for articles published between 2009 and 2019 from PubMed, Clinical Key, ScienceDirect, and Scopus databases. This study obtained four articles that meet the criteria of the randomized controlled trial (RCT), the study subjects were toddlers and conducted in developing countries. A sample of 995 children was divided into two groups, 518 children received probiotics (intervention) and 477 children received standard therapy (control). The data were analyzed by Review Manager (RevMan) software 5.3 to assess Standardized Mean Difference (SMD). Results: Probiotics administration reduced duration of acute diarrhea in children under five than standard therapy, with pooled estimate= 0.30 (SMD= -0.30; 95% CI= – 0.56 to -0.03). Conclusion: Probiotics administration combined with standard therapy is effective to reduce the duration of acute diarrhea in children under five in developing countries. Keywords: acute diarrhea, probiotic, children under five Correspondence:Nurul Aini Suria Saputri. Midwifery Department, School of Health Polytechnics, Tanjungpinang/ Masters Program in Public Health, Universitas Sebelas Maret. Jl. Arief Rahman Hakim No.1, Tanjungpinang, Riau Islands. Email: [email protected]. Mobile: +6285743401971. DOI: https://doi.org/10.26911/the7thicph.03.95

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