scholarly journals Study of hormone levels and semen parameters in infertile patients and fertile controls from Batna

2017 ◽  
Vol 1 (2) ◽  
pp. 39-40
Author(s):  
Nour El Houda Bousnane ◽  
Ali Chennaf ◽  
Mouloud Yahia
Keyword(s):  
Male Infertility ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Public Health Problem ◽  
University Hospital ◽  
Semen Parameters ◽  
Endocrine Disorders ◽  
Major Public Health Problem ◽  
Infertile Men ◽  
The Impact

Background: Male infertility or the inability of a man to procreate is a major public health problem and is a leading cause of marital discord in countries such as Algeria. Endocrine disorders that can be associated with significant medical pathology remain an important factor to be considered in the etiology of male infertility, and those disorders are usually associated with alteration of sperm count or in severe cases with azoospermia. In this study, we are evaluating semen parameters and hormonal levels of patients with idiopathic male infertility and comparing their results with healthy fertile controls. Methods: We aim to study the impact of hormones; follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T) and prolactin (PRL) on idiopathic male fertility and their impact on semen parameters, we conducted a study on 71 male subjects with 39 infertile men and 32 fertile controls from the city of Batna (Algeria). Our study lasted six months and was conducted at the University Hospital of Batna and a private analysis laboratory. Results: The results of semen analysis allowed us to determine that the most common pathology in our population is OANTS with a percentage of 21.05% followed by NS and NT with 13.16%; results of the permocytogramme show a predominance of atypical forms of the head with a frequency of 39.21%. Regarding the hormone dosage, prolactin was the most disturbed hormone with an average value of (18 ± 6.221 ng/ml), which is almost pathologic; the other hormones showed some disturbances but to a lesser degree. The results of spermiologique parameters of infertile men compared with fertile controls showed highly significant differences (P≤O.OOO1) regarding motility, concentration vitality, and spermatozoa morphology. The comparison of results of hormones between the two groups revealed differences in LH and prolactin levels; no differences were found regarding FSH and testosterones. Concerning the relationship between hormones and spermiologiques parameters, positive correlations were found between (LH and sperm concentration) (testosterone and sperm concentration), and, finally, a strong correlation was found between the levels of prolactin and the anomalies of intermediate piece of spermatozoa. Conclusion: This study showed that hormonal disorders are not a common cause of male infertility in our study population. It further showed the relative frequencies of the various semen abnormalities during the study period. Also, we found associations between altered semen parameters and pathological levels of some hormones; however, a complementary study with a more subjects is needed.

scholarly journals Relation between BMI and Semen parameters in male infertility patients in west of Algeria

2020 ◽  
Vol 10 (2-s) ◽  
pp. 64-67
Author(s):  
Dalila Ferrag ◽  
Abbassia Demmouche ◽  
Charaf Khalloua Zine
Keyword(s):  
Body Mass Index ◽  
Male Infertility ◽  
Body Mass ◽  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Infertile Men ◽  
The Mean ◽  
The Impact

Introduction: Body mass index BMI is a risk factor that influences semen quality and reduces male fertility. The aim of this study was to determine the impact of body mass index (BMI) on semen parameters in infertile men. Subject and method: A total of 446 infertile men, the study population was divided into four groups depending on their BMI , underweight (<18.5 kg/), normal weight (18.5-24.99 kg/m2 ), overweight 25-29.99 kg/m2), and obese >30.0 kg/.semen parameters (PH, volume, concentration ,total semen count ,vitality, morphology and motility ) were compared across the four BMI groups. Results: The mean of age was 41.91±6.39, the mean infertility duration was 4.92±3.28, 351(78.7٪) had primary infertility and 95(21.3٪) had secondary infertility. The mean BMI was 29.38± 4.85 and the most of patients 45.2٪ were obese. Conclusion: This study has found evidence of an association between BMI and semen parameters (Sperm concentration, Total sperm count, motility, and vitality) and no correlation between Semen volume, morphology and BMI. Keywords: Body mass index, male infertility, semen quality, west of Algeria

scholarly journals The Impact of Radiofrequency Waves on Male Infertility: A Systematic Review

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Leili Darvish ◽  
Azadeh Amraee ◽  
Marjan Akhavan Amjadi ◽  
Zahra Atarodi Kashani ◽  
Masoumeh Ghazanfarpour ◽  
...  
Keyword(s):  
Systematic Review ◽  
Male Infertility ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Membrane Integrity ◽  
Semen Parameters ◽  
Cochrane Library ◽  
Negative Effects ◽  
The Impact

Context: As the use of cellphones and other electronic devices increases, concerns about the possible effect of radiofrequency waves on health are growing. Long-term use of the cellphone may have negative effects on sperm quality. Objectives: The purpose of this research was to examine men's infertility due to the effect of radiofrequency waves. Methods: In this systematic review, language restrictions were not considered in searching the databases. Cochrane Library, Google Scholar, PubMed, EMBASE, ProQuest, CINAHL, Science Direct, MEDLINE, and Scopus were used to obtain the data from them. All data were scanned from the year 2000 until 2019. Papers selected for retrieval were evaluated by the Newcastle-Ottawa and CONSORT scales. Results: A total of 14 articles that met the inclusion criteria were ultimately assessed. Motile sperm, sperm vitality and membrane integrity, morphology, volume, total sperm count, sperm concentration, and sperm fertility were found to be influenced by radiofrequency waves. Conclusions: The results showed that RF has detrimental effects on semen parameters and due to an increase in RF wave use currently and its role in male infertility, giving information to men about adverse complications of RF is necessary. Further studies are needed to design the less harmful devices.

scholarly journals Ambient sulfur dioxide could have an impact on testicular volume from an observational study on a population of infertile male

2020 ◽  
Author(s):  
Yuan Chen ◽  
Yi-Kai Chang ◽  
Yann-Rong Su ◽  
Hong Chiang Chang
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Testicular Volume ◽  
University Hospital ◽  
Semen Parameters ◽  
Sperm Cells ◽  
Infertile Male ◽  
Negatively Associated ◽  
The Impact

Abstract Background The present retrospective study investigates the effect of environmental pollutants on male reproductive health. Methods Male patients with primary infertility (n = 282) from a single center (National Taiwan University Hospital, Taipei, Taiwan), between January 2016 and December 2017, were identified. Patients were physically examined for the presence of varicocele, and the volume of both testicles. Semen quality was measured in terms of total sperm count (millions), sperm concentration (millions/ml), and the percentage of motile sperm cells and the sperm cells with normal morphology. Data on the concentration of SO 2 (ppb), O3 (ppb), NO and NO 2 (ppb), and PM2.5 concentrations (μg/m3), measured on daily and hourly basis, were acquired from the Environmental Protection Administration Executive Yuan, Taiwan. Individual exposure to pollutants was estimated based on the reported residential address of patients. Statistical analysis indicated the impact of each pollutant on the testicular volume and semen parameters. Results Mean ± SD of age was 36.7 ± 7.3 years. The average sperm count and concentration was 41.9 million/ml and 34.1 million/ml, respectively. Except for PM2.5, the mean concentration of all the particulate matters were within the reference value. NO2 and SO2 exposure were negatively associated with the sperm concentration and motility, and testicular volume, respectively. Conclusions NO2 and SO 2 exposure were negatively associated with the sperm concentration and motility, and testicular volume, respectively, in a population of infertile male. Nevertheless, studies are needed to ascertain the impact of different exposure levels of pollutants on the semen parameters.

scholarly journals Is there a place for nutritional supplements in the treatment of idiopathic male infertility?

2014 ◽  
Vol 86 (3) ◽  
pp. 164 ◽  
Author(s):  
Davide Arcaniolo ◽  
Vincenzo Favilla ◽  
Daniele Tiscione ◽  
Francesca Pisano ◽  
Giorgio Bozzini ◽  
...  
Keyword(s):  
Male Infertility ◽  
Sperm Count ◽  
Nutritional Supplements ◽  
Semen Parameters ◽  
Male Factor ◽  
Treatment Regimens ◽  
Idiopathic Male Infertility ◽  
Infertile Men ◽  
Wide Variability

Objective: Infertility affects 15% of couples in fertile age. Male factor is a cause of infertility in almost half of cases, mainly due to oligoasthenoteratozoospermia (OAT). The purpose of this study is to review the effects of nutritional supplements as medical treatment for idiopathic male infertility. Material and methods: A Pub Med and Medline review of the published studies utilizing nutritional supplements for the treatment of male infertility has been performed. Results: Clinical trials on Vitamin E, Vitamin A, Vitamin C. Arginine, Carnitine, N-Acetyl-Carnitine, Glutathione, Coenzyme Q10, Selenium and Zinc were reviewed. Although there is a wide variability in selected population, dose regimen and final outcomes, nutritional supplements both alone and in combination seems to be able to improve semen parameters (sperm count, sperm motility and morphology) and pregnancy rate in infertile men. Conclusions: There are rising evidences from published randomized trials and systematic review suggesting that nutritional supplementation may improve semen parameters and the likelihood of pregnancy in men affected by OAT. This improvement, however, is not consistent and there is a wide variation in the treatment regimens used. Well designed and adequately powered RCTs are needed to better clarify the role of nutritional supplements as treatment for male infertility.

scholarly journals What Is the Impact of Excessive Iodine and Semen Quality in Fertile Men of China: An Association Study 

2021 ◽  
Author(s):  
Ning Wang ◽  
Fang Lv ◽  
Ge Yu ◽  
Cuige Shi ◽  
Shangming Wang ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
Male Reproduction ◽  
Semen Parameters ◽  
Human Thyroid ◽  
Urinary Iodine Concentration ◽  
The Impact

Abstract Background: Iodine is an essential element for hormones synthesized by the human thyroid gland. Thyroid hormone deficiency affects all body tissues, including multiple endocrine changes that alter growth hormones, corticotrophin, glucocorticoids, and gonadal function. In many countries, subfertility is an important problem affecting about 10–15% of all couples trying to conceive. Male subfertile factors have accounted for 25–30% of all cases in their studies. The aim of this study was to study the correlation between urinary iodine concentration (UIC) and semen quality of fertile male in China.Methods: semen and urine samples were collected from males who attended a survey for the reproductive physiological constants of male and female in China. All participants were fertile and they should be free from diseases of male reproductive system and thyroid related diseases. We studied the correlation between UIC and semen quality parameters in fertile males and the effect of iodine concentration on male reproduction. Participants were divided into six groups based on UIC. We measured semen parameters and UIC. Semen parameters or time-to-pregnancy (TTP) were analyzed by Spearman correlation, linear regression and multivariable logistic regression. Results: 1089 men were recruited in the study. The mean and median age of participants were 27.46±0.12 and 27±3.88 years, respectively. UIC of 274 (25.16%) men was lower than the UIC of WHO recommended. UIC of 405 men located in the region of WHO recommended. 62.35% of them were not located in the optimal region. Semen concentration and total sperm count were found to decrease when UIC increases when the UIC≥100 ug/L. Conclusions: A male with deficient UIC or excessive UIC has more risk of lower semen quality such as sperm concentration and total sperm count. In addition, if a male with deficient UIC or excessive UIC, his wife has longer TTP than the males who had normal UIC. Deficient UIC associated with lower semen quality and TTP than excessive UIC.

scholarly journals Semen quality pattern and age threshold: a retrospective cross-sectional study of 71,623 infertile men in China, between 2011 and 2017

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
W. N. Li ◽  
M. M. Jia ◽  
Y. Q. Peng ◽  
R. Ding ◽  
L. Q. Fan ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Cross Sectional Study ◽  
Semen Parameters ◽  
Sectional Study ◽  
Joinpoint Regression ◽  
Cross Sectional ◽  
Progressive Motility ◽  
Infertile Men

Abstract Background The aim of this study was to provide information on the semen quality pattern of infertile men and age thresholds for semen parameters in China. Methods This was a retrospective cross-sectional study investigating 71,623 infertile men from the Reproductive and Genetic Hospital of CITIC Xiangya in Hunan, China, from 2011 to 2017. The Kruskal-Wallis test, Mann-Kendall test, linear regression model and joinpoint regression were used. Results Although erratic changes were observed in the median semen parameters (sperm concentration 40.1–52.1 × 106/ml, total sperm count 117.8–153.1 × 106, sperm progressive motility 33.4–38.1%) during the 7 years of observation, no significant decrease in semen quality was found, and 47.88% of infertile men showed normal semen parameters according to the World Health Organization (WHO) criteria. According to the joinpoint regression analysis, sperm progressive motility appeared to decrease earlier than the sperm concentration and total sperm count (at 28, 58, and 42 years of age, respectively). Conclusions There is no evidence of a deterioration in semen quality among infertile men in Hunan, China. Semen parameters decreased with increasing age, with turning points noted at different ages. Semen parameters are not absolute evidence for the assessment of male fertility potential. Therefore, we believe that, among semen parameters, the sperm concentration is the best predictor of fertility for ART, followed by motility. Decreased sperm motility may affect natural pregnancy, but it is not necessary for successful IVF.

scholarly journals Impact of Cigarette Smoking on Sperm Parameters of Infertile Men in Center of Algiers (Capital of Algeria)

2020 ◽  
Vol 10 (4-s) ◽  
pp. 193-196
Author(s):  
Amina Itatahine ◽  
Abbassia Demmouche ◽  
H Maï ◽  
Z.C. Khalloua ◽  
D. Ferrag ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Male Infertility ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Sperm Parameters ◽  
Semen Parameters ◽  
Negative Effects ◽  
Negative Effect ◽  
Pass Through ◽  
And Function

Background : Cigarette smoking has negative effects on male fertility. Toxins from tobacco smoking can potentially affect sperm development and function, with a negative effect on semen parameters. In fact, the components of cigarette smoke pass through the blood-testis barrier and thus induce an alteration of sperm parameters and nucleus quality of the spermatozoa. The aim is to determine a diffence between tobbaco and no tobbaco patient and semen parameters. This article aimed to assess the relationship between smoking and male infertility. Subject and Methods : this is retrospective study focused on the effects of smoking on semen analyses.  377 men (165 non-smokers, 212  smokers) with infertility for at least 1 year were evaluated between  Mars  and  November 2018, in center of algiers (capital of Algeria). Sperm characteristics (concentration, motility, morphology, and volume) were detemined. Results: Sperm concentration, percentage motility and morphology were significantly lower in an infertile Smokers group than the infertile Nonsmokers group. We also observed that the infertility duration were significantly increased (p<0.05) in accordance with the age in an infertile Smokers group.  Our study shows that cigarette smoking is associated with reduced sperm count and motility. Conclusions: Our results suggest that cigarette smoking has an overall negative effect on semen parameters. Our study suggests that men should be advised to abstain from smoking in order to improve reproductive outcomes. Keywords: smoking, semen, male infertility, sperm, humans

scholarly journals What is The Impact of Excessive Iodine and Semen Quality in Fertile Men of China: An Association Study

2021 ◽  
Author(s):  
Ning Wang ◽  
Fang Lv ◽  
Ge Yu ◽  
Cuige Shi ◽  
Shangming Wang ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Urinary Iodine ◽  
Iodine Concentration ◽  
Male Reproduction ◽  
Semen Parameters ◽  
Human Thyroid ◽  
Urinary Iodine Concentration ◽  
The Impact

Abstract Background: Iodine is an essential element for hormones synthesized by the human thyroid gland. Thyroid hormone deficiency affects all body tissues, including multiple endocrine changes that alter growth hormones, corticotrophin, glucocorticoids, and gonadal function. In many countries, subfertility is an important problem affecting about 10–15% of all couples trying to conceive. Male subfertile factors have accounted for 25–30% of all cases in their studies. The aim of this study was to study the correlation between urinary iodine concentration (UIC) and semen quality of fertile male in China.Methods: semen and urine samples were collected from males who attended a survey for the reproductive physiological constants of male and female in China. All participants were fertile and they should be free from diseases of male reproductive system and thyroid related diseases. We studied the correlation between UIC and semen quality parameters in fertile males and the effect of iodine concentration on male reproduction. Participants were divided into six groups based on UIC. We measured semen parameters and UIC. Semen parameters or time-to-pregnancy (TTP) were analyzed by Spearman correlation, linear regression and multivariable logistic regression. Results: 1089 men were recruited in the study. The mean and median age of participants were 27.46±0.12 and 27±3.88 years, respectively. UIC of 274 (25.16%) men was lower than the UIC of WHO recommended. UIC of 405 men located in the region of WHO recommended. 62.35% of them were not located in the optimal region. Semen concentration and total sperm count were found to decrease when UIC increases when the UIC≥100 ug/L. Conclusions: A male with deficient UIC or excessive UIC has more risk of lower semen quality such as sperm concentration and total sperm count. In addition, if a male with deficient UIC or excessive UIC, his wife has longer TTP than the males who had normal UIC. Deficient UIC associated with lower semen quality and TTP than excessive UIC.

STUDY OF EFFECT OF SMOKING AND ALCOHOL CONSUMPTION ON REPRODUCTIVE HORMONES AND SEMEN PARAMETERS IN MALE PARTNERS OF INFERTILE COUPLES AT ANMMCH, GAYA, BIHAR

2021 ◽  
pp. 40-42
Author(s):  
Pankaj Kumar Chaudhary ◽  
Anupam Chaurasia ◽  
Lata Shukla Dwivedy ◽  
Debarshi Jana
Keyword(s):  
Alcohol Consumption ◽  
Male Infertility ◽  
Tobacco Smoking ◽  
Sperm Concentration ◽  
Reproductive Hormones ◽  
Semen Parameters ◽  
Male Partners ◽  
Testosterone Levels ◽  
Progressive Motility ◽  
The Impact

Background: Nearly 15% couples trying to conceive are affected by infertility, and male infertility affects nearly 50% of these. Majority of the men have no apparent reason for infertility. Tobacco smoking and alcohol intake are avoidable factors which may affect male fertility. This study aimed to evaluate the impact of tobacco smoking and alcohol consumption on serum follicle stimulating hormone (FSH) and testosterone levels and on semen microscopy parameters in male partners of infertile couples.Material and Methods: This cross sectional descriptive study, included male partners of couples presenting with infertility at Obstetrics and Gynaecology Department of ANMMCH, Gaya, Bihar. Exposure to risk factors was recorded. Serum FSH and testosterone levels and semen microscopy for sperm concentration, progressive motility and morphology were evaluated. Results: In the 98 subjects, mean FSH levels, testosterone levels, sperm concentration and sperm progressive motility were signicantly lower in smokers (P=0.001, 0.002, 0.005, 0.003 respectively). Same parameters were signicantly lower in alcoholics (P<0.001). Smokers had signicantly higher odds of abnormal testosterone levels. Alcohol consumers had signicantly higher odds of low FSH levels, abnormal testosterone levels, oligozoospermia and asthenozoospermia. Conclusions: Smoking and alcoholism may be signicant contributors to male infertility. More efforts to inform the youth about effects of smoking and alcoholism on fertility are required.

scholarly journals PREVALANCE OF MALE INFERTILITY IN INDIA: STUDIES ON THE EFFECTS OF GONADOTROPIN RELEASING HORMONES

2017 ◽  
Vol 10 (8) ◽  
pp. 208
Author(s):  
Radhakrishnan Deventhiran ◽  
Kumaresan Ramanathan ◽  
Nagamurugan Nandakumar
Keyword(s):  
Male Infertility ◽  
Sperm Motility ◽  
Sperm Count ◽  
Follicle Stimulating Hormone ◽  
Sperm Concentration ◽  
Young Male ◽  
Lifestyle Changes ◽  
Infertile Men ◽  
Infertile Group ◽  
Stimulating Hormone

Objective: Nowadays, there is an increased incidence of infertility in Indian males due to lifestyle changes. Hence, the objective of this study isevaluating the gonadotropin releasing hormones (GnRH) level in infertile young male in Indian population.Materials and Methods: In total, 56 patients having abnormal semen count and five control patients have been included in the study. All patientswere underwent sperm count and estimation of hormones includes GnRH such as follicle stimulating hormone (FSH), tri-iodothyronine, thyroxin,prolactin, and testosterone.Results: The sperm concentration of infertile men was significantly lower than control. Sperm motility behaviors rapid, sluggish, and non-motilecharacters were significantly lower than control. Among GnRH, FSH has been significantly higher in infertile group than control group.Conclusion: FSH may be considered as a marker for male infertility.

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