Bilateral Massive Retinal Gliosis Associated With Retinopathy of Prematurity

2009 ◽  
Vol 133 (8) ◽  
pp. 1242-1245 ◽  
Author(s):  
S. K. Steven Houston ◽  
T. David Bourne ◽  
M. Beatriz S. Lopes ◽  
Nicola G. Ghazi

Abstract Massive retinal gliosis (MRG) is a rare, benign intraocular condition that may develop in association with long-standing eye conditions including chronic inflammation, vascular disorders, glaucoma, trauma, or congenital abnormalities. It is thought to represent a nonneoplastic reactive tissue response to retinal injury. Here, we describe an unusual case of bilateral MRG in association with retinopathy of prematurity. To our knowledge, this may be the first report of such an occurrence. The differential diagnosis of MRG is discussed with specific emphasis on its relationship to vasoproliferative tumor of the retina and presumed acquired retinal hemangiomas. In addition, we hypothesize that MRG, vasoproliferative tumor of the retina, and presumed acquired retinal hemangiomas may represent different phenotypes along a spectrum of the same disease process.

2018 ◽  
Vol 11 (1) ◽  
pp. e226364
Author(s):  
Shilpa Ojha ◽  
Julian Gaskin ◽  
Michael Saunders

Acute lymphoblastic leukaemia (ALL) is one of the the most common malignancies of childhood and can occasionally present as acute airway obstruction. We present the unusual case of a 1-year-old boy who was referred to our Paediatric Otolaryngology (ENT) clinic with a recurrent history of croup. This is the first reported case of localised ALL presenting as a subglottic mass in a paediatric patient. It highlights the need to have a broader differential diagnosis in children presenting with ‘recurrent croup’ including extramedullary presentation of leukaemia and to have a low threshold for performing endoscopy in such cases.


2013 ◽  
Vol 61 (3) ◽  
pp. 366-375 ◽  
Author(s):  
Ivan Dinev

This paper reports an enzootic outbreak and spontaneous regression of keratoacanthomas among adult layer hens with lesions on the skin of the legs. The observations were performed in a flock of 55,000 commercial layers (50,000 Lohmann White and 5,000 Lohmann Brown). At the age of 30 weeks, Lohmann White layers exhibited a number of growths (at an average of 60 hens per week, representing 0.1% of the flock) in the region of leg toes on a daily basis over 28 weeks that regressed during the remaining flock production period. Gross and histological investigations identified the lesions as keratoacanthomas. PCR analysis was negative for avian leukosis virus (ALV) and reticuloendotheliosis virus (REV). The present investigations have revealed an unusual case: this is the first report on an enzootic outbreak of multiple keratoacanthomas in commercial layers. The results of the aetiological investigations do not show a relation to any infectious agent or a chemical-toxic cause. The abnormal invasion of keratinocytes from the stratum corneum leading to neoplasms in this case coincides with the phase of peak laying capacity which is in fact a stress factor and might be regarded as a provocative moment.


2021 ◽  
Vol 53 (3) ◽  
Author(s):  
Andreia Garcês ◽  
Vanessa Soeira ◽  
Sara Lóio ◽  
Isabel Pires

Pyometra is a pus accumulation in the uterine lumen. This paper reports an unusual case of pyometra in a female Sus scrofa of Parque Biologico de Gaia (Avintes, Portugal). The animal was of advanced age, and the clinical signs (e.g., anorexia, lethargy) were originally associated with geriatric conditions. The animal presented a large uterus, which likely further contributed to the locomotion difficulties and poor body condition. To the extent of our knowledge, this is the first report of a close pyometra in wild boar (Sus scrofa, Linnaeus, 1758). However, this diagnosis must be taken into account during uterine evaluation and special attention must be given to its inspection in meat animals.


Author(s):  
Rosa Lillo ◽  
Angelica Bibiana Delogu ◽  
Gessica Ingrasciotta ◽  
Gianluigi Perri ◽  
Maria Grandinetti ◽  
...  

A woman complaining of dyspnea and chest pain since childhood, was referred to our hospital with an initial diagnosis of biventricular hypertrophic cardiomyopathy. Multimodality imaging evaluation revealed massive right ventricular (RV) hypertrophy and severe RV outflow tract obstruction, with a final diagnosis of double chambered RV associated with small ventricular septal defect with right-to-left shunt and right partial anomalous pulmonary vein return. This represents an uncommon combination of congenital abnormalities, extremely rarely diagnosed in adulthood.


2013 ◽  
Vol 04 (04) ◽  
pp. 453-456 ◽  
Author(s):  
Amandeep Kumar ◽  
Bhawani S. Sharma ◽  
Shashank S. Kale ◽  
Ajay Garg ◽  
M. C. Sharma

ABSTRACTAstrocytomas of Conus‑Cauda equina region are rare. Astrocytomas, which are intramedullary tumors, may rarely have an extramedullary component. However, primary intradural extramedullary astrocytomas are extremely rare, with very few cases reported in the literature. We describe a giant extramedullary pilocytic astrocytoma of Cauda equina in a 20‑year‑old male. To the best of our knowledge, this is the first report of such a case in the available literature. This case highlights the fact that astrocytomas can be primarily extramedullary and emphasizes the need to consider pilocytic astrocytoma in the differential diagnosis of cystic Cauda equina tumors.


2018 ◽  
Author(s):  
Scott D Lifchez ◽  
Colton McNichols

Hand infections are a common concern in the emergency, outpatient, and inpatient setting. It is important to accurately diagnose and treat these infections to minimize the risk of spread or functional deficit that could be permanent if not addressed in a timely manner. In this chapter, we aim to cover the epidemiology and etiology of hand infections along with how they tend to present in the clinical setting. This chapter is written so that each encounter can be analyzed in a logical, step-wise fashion from formulating a differential diagnosis to treatment. Upon evaluation, it is important to perform a thorough clinical examination in addition to knowing which imaging modalities can help elucidate the pathology when the initial presentation is unclear. These and other diagnostic studies are covered so that the differential diagnosis can be narrowed down. Each of the possible scenarios is clarified further to help confirm the most likely diagnosis. Finally, we touch on each treatment (whether surgical or medical) recommended for the suspected disease process. Overall, it is important to discern whether the patient will need a small procedure, surgery, or medication alone so that the appropriate management is performed and optimal healing is possible. This review contains 25 Figures, 10 Tables and 26 references Key Words: acute infection, chronic infection, paronychia, felon, flexor tenosynovitis, septic joint, hand infection, hand surgery


2000 ◽  
Vol 124 (10) ◽  
pp. 1553-1556
Author(s):  
David S. Brenner ◽  
Stephen C. Jacobs ◽  
Cinthia B. Drachenberg ◽  
John C. Papadimitriou

Abstract A 69-year-old woman presented with a large left retroperitoneal suprarenal mass. Radical resection of the left kidney and the mass revealed a cystic adrenal tumor with a weight of 1500 g. Histologic examination showed that the cyst was composed mostly of partially organized clotted blood. The periphery of the mass consisted of a thin rim of cortical and medullary adrenal tissue with superimposed granulomatous chronic inflammation. The infectious nature of the process was manifested by the scattered intracellular and extracellular Leishmania amastigotes that were found throughout the lesion. The differential diagnosis of cystic adrenal masses and the unusual presentation of visceral leishmaniasis are discussed in this context.


Author(s):  
Swati Singh ◽  
Ravinder Ahlawat

Rupture of uterus is characterized by a breach in the wall of the uterus involving its full thickness. An unscarred uterus rupture is uncommon. It has non-specific symptoms and presentation differs according to site and time of rupture. Authors report an unusual case of spontaneous rupture of unscarred uterus. A 32-year-old, pregnant woman, developed postpartum bleeding with no history of prior uterine incision. She was diagnosed as a case of rupture of uterus and emergency laparotomy was done. Early diagnosis and immediate surgical intervention may significantly improve the prognosis. Differential diagnosis of uterine rupture should always be kept in mind in all patients with or without risk factors.


2016 ◽  
Vol 21 (2) ◽  
pp. 119-121
Author(s):  
Abdullah Al Mamun ◽  
Dewan Mahmud Hasan

Seborrheic keratosis is a benign tumour of skin, a common hyperkeratotic lesion of the epidermis,that usually occurs in the trunk and less frequently in the extremities, face and the scalp. A 65-year old farmer presented with a long standing, slowly growing, firm, redbrown, polypoidal mass about 2×2.5 cm in size, located at the skin mucosa interfare of the tip of nose. The lesion was excised under general anesthesia and histopathologic examination showed seborrheic keratosis. Diagnosis is made on the basis of clinical & histopathological examination. Here, we discuss the clinical presentation, differential diagnosis, pathological diagnosis and management of such a case. There was no recurrence during a year follow-up.Bangladesh J Otorhinolaryngol; October 2015; 21(2): 119-121


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