scholarly journals Balancing Boutique-Level Quality and Large-Scale Production: The Impact of “More Product, Less Process” on Digitization in Archives and Special Collections

2012 ◽  
Vol 13 (1) ◽  
pp. 50-63 ◽  
Author(s):  
Shan C. Sutton

Introduction Few writings within the realms of archives and special collections have reverberated throughout the field to the degree of Mark A. Greene and Dennis Meissner’s 2005 article “More Product, Less Process: Revamping Traditional Archival Processing.”1 Its clarion call to shift archival arrangement and description away from time-consuming, detailed processes toward rapid, minimalist strategies was met with both cheers and groans that continue unabated. In a sign of its ubiquity, the approach advocated by Greene and Meissner is now simply referred to as “MPLP,” and its implementation is the subject of ongoing discussion in numerous venues, including professional journals, conference . . .

2020 ◽  
Author(s):  
Alleksandr Lukanin

The monograph examines the currently existing industrial gas emissions in the chemical, petrochemical, microbiological, pharmaceutical and related industries, methods for calculating their quantity and methods for protecting the air basin from them. The materials are based on an in-depth analysis of methods for cleaning frequently occurring, most dangerous substances that enter the Earth's atmosphere with waste gases of large-scale production. Recommendations are given on methods for calculating gross emissions of harmful substances for a large number of specific industries. The subject of the monograph is related to the scientific areas "Technosphere safety" and "Engineering environmental protection", training profiles: engineering environmental protection of localities, engineering environmental protection of industrial enterprises and environmental protection and resource conservation. It will be of interest to engineering and technical staff, graduate students and teachers.


2015 ◽  
Vol 3 (37) ◽  
pp. 19123-19128 ◽  
Author(s):  
Bert Conings ◽  
Aslihan Babayigit ◽  
Tim Vangerven ◽  
Jan D'Haen ◽  
Jean Manca ◽  
...  

In this paper, the impact of the water content (up to 10 vol%) in DMF-based precursors on organometal halide perovskites is investigated. The photovoltaic performance is found not to be affected, thus relaxing the conditions for large-scale production of this upcoming photovoltaic technology.


2020 ◽  
Author(s):  
Lindsey Robinson-McCarthy ◽  
Alexander J. Mijalis ◽  
Gabriel T Filsinger ◽  
Helena de Puig ◽  
Nina M. Donghia ◽  
...  

The SARS-CoV-2 pandemic has brought about the unprecedented expansion of highly sensitive molecular diagnostics as a primary infection control strategy. At the same time, many laboratories have shifted focus to SARS-CoV-2 research and diagnostic development, leading to large-scale production of nucleic acids that can interfere with these tests. We have identified multiple instances, in independent laboratories, in which nucleic acids generated in research settings are suspected to have caused researchers to test positive for SARS-CoV-2 in surveillance testing. In some cases, the affected individuals did not work directly with these nucleic acids, but were exposed via a contaminated surface or object. Though researchers have long been vigilant of DNA contaminants, the transfer of these contaminants in SARS-CoV-2 testing samples results in anomalous test results. The impact of these stretches into the public sphere, placing additional burdens on public health resources, placing affected researchers and their contacts in quarantine, and carrying the potential to trigger shutdowns of classrooms and workplaces. We report our observations as a call for increased stewardship over nucleic acids with the potential to impact both use and development of diagnostics. These experiences highlight a neglected aspect of the test, trace, isolate public health strategy for managing COVID-19: we cannot easily identify and diagnose an erroneous test result. To prevent undue personal and economic strain and maintain faith in the testing process, we propose: a test, isolate, verify, and trace approach to COVID-19 diagnosis in research and clinical diagnostic workplaces.


2018 ◽  
Vol 5 (2) ◽  
Author(s):  
P. Dhanasekaran ◽  
M. Sumathy

This paper intends to analyse the impact of some selected macroeconomic factors on the economies of BRICS nations during the pre and post BRICS era. The analysis done based on the paired sample t-test found a significant impact on the imports, exports, GDP, REER and GCF of BRICS economies during the pre and post BRICS era. The impact is very significant in India as well. The study concluded that though these economies have many challenges to sustain and maintain the trend. FDI will facilitate these economies to enhance large scale production, employment and sustainability.


1977 ◽  
Vol 10 (2) ◽  
pp. 113-135 ◽  
Author(s):  
Carl-Göran Hedén

To talk about enzyme engineering in a context of global problems might seem easy, because the subject is so dynamic and its ramifications so numerous. One might for instance talk about the industrial use of immobilized enzymes to achieve steroid transformations suitable for large-scale production of drugs reducing fertility, or one could describe the application of the same technique for chopping off side-chains of penicillin and other antibiotics as a first step in the production of new semisynthetic drugs, that certainly have a global impact. Or it would be tempting to review the potential of enzyme engineering for synthesizing physiologically active polypeptides that find use in husbandry or medicine.


2021 ◽  
Vol 8 ◽  
Author(s):  
Yanhui Yao ◽  
Hongya Li ◽  
Jia Li ◽  
Baocheng Zhu ◽  
Tongguo Gao

The study evaluated the impact of fermentation with Bacillus sp. on the nutritional quality of soybean meal (SBM) and the changes of bacterial community structure during fermentation. High protease-producing strains were screened to degrade SBM macromolecular protein and anti-nutritional factors (ANFs). Unsterilized SBM then underwent an anaerobic solid-state fermentation method to evaluate the effects of fermentation. Results showed that for the nine high-producing protease strains that were screened, acid-soluble protein (ASP) contents in fermented SBM increased, with the highest value found to be 13.48%, which was fermented using strain N-11. N-11 was identified as Bacillus subtilis. N-11 fermentation reduced ANFs such as glycinin and β-conglycinin by 82.38 and 88.32%, respectively. During N-11 fermentation, the bacterial richness and diversity in SBM increased but not significantly. The high-yield protease strain B. subtilis N-11 selected in this experiment improved the nutritional quality of SBM through fermentation, and it can be used for industrial large-scale production.


2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
A. M. Al Taweel ◽  
Q. Shah ◽  
B. Aufderheide

The impact of mixing on the promotion of microorganism growth rate has been analyzed using a multiphase forced-circulation pipe-loop reactor model capable of identifying conditions under which it is possible to convert natural gas into Single-Cell Protein. The impact of mixing in the interphase mass transfer was found to exert a critical role in determining the overall productivity of the bioreactor, particularly at the high cell loadings needed to reduce the capital costs associated with the large-scale production needed for the production of relatively low-value SCP in a sustainable manner.


2019 ◽  
Vol 18 (1) ◽  
pp. 5
Author(s):  
Iracema De Oliveira Moraes ◽  
Regina De Oliveira Moraes Arruda ◽  
Rodrigo De Oliveira Moraes ◽  
Maria Josiane Conti Moraes

The most promising and innovative alternative to biodiesel production is presented by the algae (micro and macroalgae), which have been classified by scientists as a source of third generation biofuels. The large-scale production of biodiesel from microalgae and macroalgae bioethanol production will happen much faster than you think. It is believed that its full commercialization is possible within a few years, and with a competitive price compared to diesel produced from petroleum, the same occurring for bioethanol. The use of seaweed as a feedstock for the production of biofuels has been seen as a less environmentally impactful as the biomass produced on the continent and its potential is very high. Several groups in Latin America (Brazil, of course) are studying micro and macroalgae not only for biofuels production (biodiesel, bioethanol, biohydrogen) but also to do wastewater treatment. This paper will discuss the presentations done in four annual courses (2010, 2011, 2012, 2013) promoted by the Biotechnology Brazilian Argentine Center, BBAC, and offered to fellowships (sixteen per year), from Brazil, Argentina, Colombia, Paraguay and Uruguay. Arthrospira (Spirulina) platensis was chosen as a cyanobacteria model in the courses, due to its feasibility of cultivation, many publications about the subject and the existence of strains isolated in Brazil.


2021 ◽  
Vol 8 ◽  
Author(s):  
Maria de Fátima Brito ◽  
Carla Torre ◽  
Beatriz Silva-Lima

Diabetes Mellitus is one of the World Health Organization's priority diseases under research by the first and second programmes of Innovative Medicines Initiative, with the acronyms IMI1 and IMI2, respectively. Up to October of 2019, 13 projects were funded by IMI for Diabetes & Metabolic disorders, namely SUMMIT, IMIDIA, DIRECT, StemBANCC, EMIF, EBiSC, INNODIA, RHAPSODY, BEAT-DKD, LITMUS, Hypo-RESOLVE, IM2PACT, and CARDIATEAM. In general, a total of €447 249 438 was spent by IMI in the area of Diabetes. In order to prompt a better integration of achievements between the different projects, we perform a literature review and used three data sources, namely the official project's websites, the contact with the project's coordinators and co-coordinator, and the CORDIS database. From the 662 citations identified, 185 were included. The data collected were integrated into the objectives proposed for the four IMI2 program research axes: (1) target and biomarker identification, (2) innovative clinical trials paradigms, (3) innovative medicines, and (4) patient-tailored adherence programmes. The IMI funded projects identified new biomarkers, medical and research tools, determinants of inter-individual variability, relevant pathways, clinical trial designs, clinical endpoints, therapeutic targets and concepts, pharmacologic agents, large-scale production strategies, and patient-centered predictive models for diabetes and its complications. Taking into account the scientific data produced, we provided a joint vision with strategies for integrating personalized medicine into healthcare practice. The major limitations of this article were the large gap of data in the libraries on the official project websites and even the Cordis database was not complete and up to date.


2020 ◽  
Vol 10 (22) ◽  
pp. 8181
Author(s):  
Mladen Bošnjaković ◽  
Nazaruddin Sinaga

We have had high expectations for using algae biodiesel for many years, but the quantities of biodiesel currently produced from algae are tiny compared to the quantities of conventional diesel oil. Furthermore, no comprehensive analysis of the impact of all factors on the market production of algal biodiesel has been made so far. This paper aims to analyze the strengths, weaknesses, opportunities, and threats associated with algal biodiesel, to evaluate its production prospects for the biofuels market. The results of the analysis show that it is possible to increase the efficiency of algae biomass production further. However, because the production of this biodiesel is an energy-intensive process, the price of biodiesel is high. Opportunities for more economical production of algal biodiesel are seen in integration with other processes, such as wastewater treatment, but this does not ensure large-scale production. The impact of state policies and laws is significant in the future of algal biodiesel production. With increasingly stringent environmental requirements, electric cars are a significant threat to biodiesel production. By considering all the influencing factors, it is not expected that algal biodiesel will gain an essential place in the fuel market.


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