The development of analytical procedures using ICP-OES and ICP-MS for the analysis of trace metals in pharmaceutical formulations

The performance of axial view ICP OES and ICP-MS techniques were compared through the determination of As, Fe, Mn, Pb, Sb and Sn in electrolytic copper. Samples were prepared by two procedures: 1. Total dissolution with 5 % v/v HNO3 and 2. Dissolution with 1.4 % v/v HNO3 plus 2.0 % v/v H2SO4, followed by separation of the Cu by electrodeposition. The methods were applied for the analysis of standard copper solutions, using calibration against aqueous solutions with or without the addition of Cu. The results obtained by the two techniques were similar, but the separation of Cu from the sample matrix proved to be more adequate for practical reasons.

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Characterisation of airborne particulates and associated trace metals deposited on tree bark by ICP-OES, ICP-MS, SEM-EDX and laser ablation ICP-MS

Atmospheric Environment ◽

10.1016/j.atmosenv.2005.12.022 ◽

2006 ◽

Vol 40 (14) ◽

pp. 2626-2634 ◽

Cited By ~ 72

Author(s):

Keiko Suzuki

Keyword(s):

Laser Ablation ◽

Trace Metals ◽

Tree Bark ◽

Icp Oes ◽

Airborne Particulates ◽

Icp Ms

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Studies on the Content of Selected Technology Critical Elements (Germanium, Tellurium and Thallium) in Electronic Waste

Materials ◽

10.3390/ma14133722 ◽

2021 ◽

Vol 14 (13) ◽

pp. 3722

Author(s):

Joanna Willner ◽

Agnieszka Fornalczyk ◽

Magdalena Jablonska-Czapla ◽

Katarzyna Grygoyc ◽

Marzena Rachwal

Keyword(s):

Solar Cell ◽

New Technologies ◽

Electronic Waste ◽

Quantitative Composition ◽

Icp Oes ◽

Electronic Components ◽

Critical Elements ◽

Weee Recycling ◽

Icp Ms ◽

And Migration

The article draws attention to the problem of the presence of metals: germanium (Ge), tellurium (Te), thallium (Tl), and others (Cd, Ba, Co, Mn, Cr, Cu, Ni, Pb, Sr, and Zn) in selected waste of electrical and electronic equipment (WEEE). As a result of the growing demand for new technologies, the global consumption of TECs has also been increasing. Thus, the amount of metals in circulation, of which the impacts on the environment have not yet been fully understood, is constantly increasing. Due to the low content of these metals in WEEE, they are usually ignored during e-waste analyses. The main aim of this study was to determine the distribution of Ge, Te, and Tl (and other elements) in ground sieve fractions (1.0, 0.5, 0.2, and 0.1 mm) of selected electronic components (solar lamps, solar cell, LED TV screens, LCD screens, photoresistors, photodiodes, phototransistors) and to determine the possible tendency of the concentrations of these metals in fractions. This problem is particularly important because WEEE recycling processes (crushing, grinding, and even collection and transport operations) can lead to dispersion and migration of TCE pollutants into the environment. The quantitative composition of e-waste was identified and confirmed by ICP-MS, ICP-OES and SEM-EDS, and XRD analyses. It was found that Ge, Te, and Tl are concentrated in the finest fractions of ground e-waste, together with Cd and Cr, which may favor the migration of these pollutants in the form of dust during storage and processing of e-waste.

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Comparison of Serum, Plasma, and Liver Zinc Measurements by AAS, ICP-OES, and ICP-MS in Diverse Laboratory Settings

Biological Trace Element Research ◽

10.1007/s12011-021-02883-z ◽

2021 ◽

Author(s):

Andrew G. Hall ◽

Janet C. King ◽

Christine M. McDonald

Keyword(s):

Inductively Coupled Plasma ◽

Method Development ◽

Geometric Mean ◽

Zinc Content ◽

Plasma Zinc ◽

Icp Oes ◽

Percent Error ◽

Accuracy And Precision ◽

Icp Ms ◽

Standardized Method

AbstractProgress improving zinc nutrition globally is slowed by limited understanding of population zinc status. This challenge is compounded when small differences in measurement can bias the determination of zinc deficiency rates. Our objective was to evaluate zinc analytical accuracy and precision among different instrument types and sample matrices using a standardized method. Participating laboratories analyzed zinc content of plasma, serum, liver samples, and controls, using a standardized method based on current practice. Instrument calibration and drift were evaluated using a zinc standard. Accuracy was evaluated by percent error vs. reference, and precision by coefficient of variation (CV). Seven laboratories in 4 countries running 9 instruments completed the exercise: 4 atomic absorbance spectrometers (AAS), 1 inductively coupled plasma optical emission spectrometer (ICP-OES), and 4 ICP mass spectrometers (ICP-MS). Calibration differed between individual instruments up to 18.9% (p < 0.001). Geometric mean (95% CI) percent error was 3.5% (2.3%, 5.2%) and CV was 2.1% (1.7%, 2.5%) overall. There were no significant differences in percent error or CV among instrument types (p = 0.91, p = 0.15, respectively). Among sample matrices, serum and plasma zinc measures had the highest CV: 4.8% (3.0%, 7.7%) and 3.9% (2.9%, 5.4%), respectively (p < 0.05). When using standardized materials and methods, similar zinc concentration values, accuracy, and precision were achieved using AAS, ICP-OES, or ICP-MS. However, method development is needed for improvement in serum and plasma zinc measurement precision. Differences in calibration among instruments demonstrate a need for harmonization among laboratories.

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