scholarly journals Metabolic syndrome in the population of psychiatric patients in Novi Sad

2020 ◽  
Vol 45 (4) ◽  
pp. 145-152
Author(s):  
Dušan Kuljančić
Keyword(s):  
Metabolic Syndrome ◽  
Atypical Antipsychotics ◽  
Psychotic Disorders ◽  
Psychiatric Patients ◽  
Study Data ◽  
Hospitalized Patients ◽  
Male Dominance ◽  
Psychiatric Clinic ◽  
The Metabolic Syndrome ◽  
Novi Sad

OBJECTIVES: The aim of this study is to determine the prevalence of metabolic syndrome (MetS) in a sample of hospitalized patients and to relate it to socio-demographic characteristics, psychiatric diagnosis and psycho-pharmacotherapy. METHODS: The study was conceived as a retrospective cohort study. Data of interest for this research were collected from the medical history of hospitalized patients at the Clinic for Psychiatry KCV in the period from January 2018 to January 2020. RESULTS: Out of a total of 2409 patients hospitalized at the Psychiatric Clinic, 1327 patients had criteria for metabolic syndrome, with a high prevalence of 55.1% among this population. Although there are more respondents in the sample (55.7%), males with a diagnosis of MetS (58.1%) dominate. The data show that the prevalence of metabolic syndrome increases statistically significantly with the age of psychiatric patients. However, the prevalence of metabolic syndrome in the study population younger than 30 years is about 33%. Among patients with incomplete primary school, 67% have a diagnosis of metabolic syndrome, which is statistically significantly higher than other compulsory profiles (p <0.001). The study sample shows a statistically significantly higher prevalence of metabolic syndrome among patients treated for psychotic disorders, with as much as 67% prevalence. Therapy with atypical antipsychotics was most associated with metabolic syndrome in 67.5% of patients, followed by a combination of 2 or more antipsychotics with 60.7% (x²=26.99, p<0.0019). Abdominal obesity is the strongest predictor of the response that the subjects will suffer from the metabolic syndrome, the quotient of which is 1.34 by logistic regression. Another important predictor refers to triglyceridemia, whose probability quotient is 1.12. CONCLUSION: The prevalence of metabolic syndrome in psychiatric patients in Novi Sad is alarmingly high, in more than half of patients, especially those treated for psychotic and mood disorders and using atypical antipsychotics and combinations of antipsychotics. In a patient with metabolic syndrome there is male dominance, low educational profile and the prevalence increases statistically significantly with increasing age of psychiatric patients.

Inflammatory cytokines and features of the metabolic syndrome among patients treated with atypical antipsychotics

2003 ◽  
Vol 60 (1) ◽  
pp. 350
Author(s):  
N. Alme´ras ◽  
M.F. Demers ◽  
J. Villeneuve ◽  
M.A. Roy ◽  
R.H. Bouchard ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Inflammatory Cytokines ◽  
Atypical Antipsychotics ◽  
The Metabolic Syndrome

Most frequent clinic comorbibities in hospitalized patients in a psychiatric clinic

2016 ◽  
Vol 33 (S1) ◽  
pp. S379-S379
Author(s):  
J. Jaber ◽  
J. Veríssimo ◽  
T.T. Raposo ◽  
B. Reys
Keyword(s):  
Psychiatric Patients ◽  
Time Frame ◽  
Health Condition ◽  
Physical Activities ◽  
Hospitalized Patients ◽  
Psychiatric Clinic ◽  
Minimum Period ◽  
Global Improvement ◽  
Patient Health ◽  
Competing Interest

IntroductionBeing hospitalized in a psychiatric clinic, patients present, in addition to the diseases that determine the hospitalization, clinic comorbidities, generally decompensated.ObjectivesTo present the most frequent clinic pathologies in a population of hospitalized patients having diverse mental disorders and establish a protocol for investigation and their early treatment.AimsTo know the most frequent pathologies in a population of hospitalized psychiatric patients and establish a protocol for their assesment, in a way that contributes to the global improvement of the patient health condition.MethodsFor its mission realization, the clinic counts on a multidisciplinary team. The participants were 762 patients, seen in the referred clinic, which presented a minimum period of hospitalization of 10 days and that were submitted to thorough clinic exam and complementary routine exams. The time frame referred to the period of March of 2012 to February of 2014, totalizing 24 months.ResultsIn the patients that had medical release after periods of hospitalization of, 90-day average, were obtained, in the totality of the cases, excellent evolution, evidenced by the improvement of the laboratory parameters.ConclusionsThe results were achieved in the hospitalization system with careful medicament administration, differentiated diets established in agreement with the patients, supervised physical activities and psychological and psychiatric support.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Association between the HTR2C rs1414334 C/G gene polymorphism and the development of the metabolic syndrome in patients treated with atypical antipsychotics

PeerJ ◽  
2016 ◽  
Vol 4 ◽  
pp. e2163 ◽  
Author(s):  
José María Rico-Gomis ◽  
Antonio Palazón-Bru ◽  
Irene Triano-García ◽  
Luis Fabián Mahecha-García ◽  
Ana García-Monsalve ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Logistic Regression ◽  
Regression Models ◽  
Atypical Antipsychotics ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
The Metabolic Syndrome

Few studies have assessed the association between the rs1414334 C/G polymorphism in the HTR2C gene and the development of the metabolic syndrome in patients treated with atypical antipsychotics. To provide further evidence, a cross-sectional study was conducted in Spain between 2012 and 2013 in 166 patients with these characteristics. In these patients, the association between the polymorphism and the presence of the metabolic syndrome was determined by implementing binary logistic regression models adjusted for variables associated with the metabolic syndrome. We did not confirm previous claims that the C allele of the polymorphism was linked to the metabolic syndrome: the association was in the opposite direction and non-significant. This conclusion held after taking gender and lifestyle variables into account.

scholarly journals CORRELATION OF RADIOGRAPHIC DAMAGE AND METABOLIC SYNDROME IN SPONDYLOARTHRITIS: A CROSS-SECTIONAL STUDY

2019 ◽  
pp. 56-60
Author(s):  
HENDRA GUNAWAN ◽  
SONY WIBISONO MUDJANARKO ◽  
AWALIA ◽  
LITA DIAH RAHMAWATI ◽  
JOEWONO SOEROSO ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Disease Activity ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Study Data ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Cross Sectional Design

Background: Cardiovascular complication remains the long-term complications in spondyloarthritis (SpA). Previous studies revealed that metabolicsyndrome is the risk factor of cardiovascular in SpA patients. Previous studies also revealed that the prevalence of the metabolic syndrome is 34.9–45.7% in SpA patients. However, previous studies also revealed the controversy of the correlation of SpA’ disease activity with metabolic syndrome.Aim: The aim of the study was to investigate the correlation of SpA’ radiographical damage measured with a modified Stoke Ankylosing SpondylitisSpinal Score (mSASSS) score with metabolic syndrome in SpA patients, which routinely visited Rheumatology Outpatient Department in Dr. SoetomoGeneral Hospital.Methods: An observational study with cross-sectional design with consecutive sampling technique was conducted in July–October 2018. All SpApatients who fulfilled the inclusion criteria were included in this study. Data analysis was performed with SPSS v21.0.Results: There were 33 SpA patients (10 males and 23 females) included in this study. The average age was 48.18±12.27 years-old. The averagemSASSS score was 24,36 (K:0.93, p:0.00). Metabolic syndrome was diagnosed in 54.5% patients with 100% patients had central obesity, 66.7% hadincreased blood pressure, 61.5% had impaired fasting glucose, 55.6% had increased triglycerides, and 77.8% had decreased high-density lipoproteincholesterol. Positive correlation between mSASSS score and metabolic syndrome was observed (r:0.510, p:0.002).Conclusion: A correlation between SpA disease activity measured with mSASSS score and metabolic syndrome was observed. Therefore, routinemetabolic syndrome screening is strongly suggested for SpA patients.

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