scholarly journals The role of rapid tissue expansion in separating xipho-omphalopagus conjoined twins in Vietnam

2021 ◽  
Vol 48 (4) ◽  
pp. 378-383
Author(s):  
Tran Thiet Son ◽  
Pham Thi Viet Dung ◽  
Ta Thi Hong Thuy ◽  
Vu Duy Kien ◽  
Nguyen Thanh Liem

Conjoined twins are rare, and each set of conjoined twins has a unique conjoined anatomy. It is necessary to perform separation to increase the chance of patient survival. Tissue expansion is an advanced technique for providing sufficient soft tissue and skin for wound closure. We report the successful application of rapid tissue expansion in 10-month-old xipho-omphalopagus conjoined twins in Vietnam. A tissue expander was placed on the anterior body between the sternum and umbilicus with a baseline of 70 mL sterile saline (0.9% NaCl). The first injection into the tissue expander began on the 6th day after expander insertion, and injections continued every 2 days with approximately 30–70 mL per injection according to the expansion of the skin. The expander reached 335 mL after six injections and within 10 days. In order to prepare for surgical separation, expansion was completed on the 15th day after insertion. The expanded skin area was estimated to be 180 cm2, which was sufficient to cover both patients’ skin deficiencies. The twins presented for surgical separation 6 days following the completion of tissue expansion. Both babies were discharged in good health 1 month after separation.


1987 ◽  
Vol 14 (3) ◽  
pp. 543-548 ◽  
Author(s):  
Malcolm W. Marks ◽  
Louis C. Argenta ◽  
James W. Thornton
Keyword(s):  


Author(s):  
Bisma Laeeque

Retinol and Tocopherol are commonly known as fat soluble Vitamin A and D. This research was undertaken with the objective to study Vitamin A and D’s effect in combating smog caused illness among females. This case report highlights diseases caused among young woman of Lahore due to smog. Hypothesis formulated for this study was accepted after testing that intake of daily-recommended amount of Vitamin A and D by females helps them in fighting diseases caused by smog. An intervention based on Food and Nutrition Board’s Recommended Dietary Allowances (RDAs) was planned. After the analysis of data by SPSS and excel, it was indicated that women could fight smog caused diseases better by including Vitamin A and D in their daily diet. It was also found that a strong positive correlation existed between good health condition among females and intake of Vitamin A and D.



2021 ◽  
pp. 014556132110079
Author(s):  
Tongyu Cao ◽  
Qingguo Zhang

Objectives: Ear reconstruction is a challenging surgery for the complicated conditions in patients with microtia. The tissue expansion techniques were necessary and relatively safe for patients with insufficient soft tissue. However, complications such as necrosis of expanded flap and exposure of tissue expander limited the popularization of this method. This study described the use of modified Brent method to handle the exposure of the postauricular tissue expander. Methods: From January 2013 to December 2019, 27 ear reconstruction patients with trauma or necrosis on an expanded skin flap and subsequent exposure of tissue expander were treated with modified Brent method, which consisted of 3 stages: removal of the expander, tension-free closure of wound, and framework fabrication; elevation of reconstructed ear; lobule rotation; and minor modification. Results: Fifty-six percent of exposures occurred in the lower pole of the tissue expander. Exposure usually occurred 54.5 days after implantation. The majority of reconstructed ears had a satisfactory appearance and showed relatively stable outcomes. Only one case of cartilage exposure required revision surgery and was repaired by the temporoparietal fascia. Conclusion: With reasonable distribution of expanded flap, prolonged interval, and sutures under tension-free conditions, complications like the occurrence of trauma or necrosis-induced exposure of tissue expander can be repaired efficiently by a staging modified Brent method.



1970 ◽  
Vol 10 (4) ◽  
pp. 289-292
Author(s):  
F Sharmin ◽  
F Begum ◽  
T Parveen ◽  
SF Khatun ◽  
W Fatima

A patient at her 38+ wks of pregnancy as a ultrasonographically diagnosed case of conjoined twin admitted in our department with ruptured membrane. Two live female babies joined at the chest were delivered by caesarean section. The parents refused a separation operation and the mother and the babies were discharged from hospital at 6th post natal day. A review of the literature suggests that early diagnosis by a combination of ultrasound and MRI is essential for management as it provides prognosis for viability and process of surgical separation and also the opportunity for early counseling of parents and termination if indicated. Key world: Conjoined twins; thoracopagus; prenatal diagnosis; separation procedure DOI: http://dx.doi.org/10.3329/bjms.v10i4.9504 BJMS 2011; 10 (4): 289-292



2006 ◽  
Vol 33 (3) ◽  
pp. 290-304 ◽  
Author(s):  
David R. Buchanan

This article describes two models for thinking about the purposes of health education—a medical model and an educationmodel—andtraces how concerns about the validity of research have driven preferencefor the medical model. In the medical model, the purpose of health education is to develop effective interventions that will prevent people from adopting unhealthy behaviors. Here, health educators are expected to replicate the methods identified by researchers to effect targeted changes in health behavior. The article then describes an alternative way of thinking about the purposes of health education. In pursuing a philosophy of education, the purpose of research and practice would be to clarify basic social values and to strengthen one's faculty for making value judgments. Practitioners here use research results as a stimulus for dialogue about the role of good health habits in living the kind of life that community members find most valuable.



2022 ◽  
Vol 48 (1) ◽  
pp. 9-26
Author(s):  
Tenley Conway ◽  
Jihan Khatib ◽  
Janele Tetreult ◽  
Andrew Almas

Many municipalities are working to protect and grow their urban forest, including adopting private tree regulations. Such regulations typically require property-owners to apply for a permit to remove trees and, if the permit is granted, plant replacement trees. Even with such regulations, many private trees are removed each year, particularly on residential property. Property-level construction activity, including expanding building footprints, replacing an older home with a new one, and increasing hardscaping, is emerging as a key driver of residential tree loss. This study addresses whether homeowners who receive a permit to remove one or more trees comply with the requirement to plant replacement trees to better understand the effect of private tree regulation. We explore this question through a written survey of homeowners who received a tree removal permit and site visits in Toronto (Ontario, Canada). While 70% of all survey participants planted the required replacement trees 2 to 3 years after receiving the permit, only 54% of homeowners whose permit was associated with construction planted. Additionally, most replacement trees were in good health but were dominated by a few genera. We also found significant differences in replacement planting and tree survival across the city’s 4 management districts. This study highlights that if resources supporting private tree regulations are limited, tree permits associated with construction should be prioritized for follow-up. Additionally, guidance about diverse species to plant should be communicated to ensure that private tree regulations are supporting the long-term protection of the urban forest.



2022 ◽  
Author(s):  
Hefeng Sun ◽  
Pengfei Sun ◽  
Haiyue Jiang ◽  
Qinghua Yang ◽  
Tongtong Li ◽  
...  

Abstract The tissue expansion technique is the most suitable procedure for Chinese patients with microtia. However, it is difficult to determine whether the expanded flap is sufficient, and there are no clear or objective guidelines for determining the volume of the expander for different sizes of auricles. One hundred patients with unilateral microtia who visited our department in 2021 were randomly selected for auricular data collection using 3D scanning. The auricle length, width, projection, perimeter, and surface area were measured. Eight different volumes of expanders underwent CT and the surface areas of these expanders were measured. The surface areas of the auricles and expanders were compared and the correlation between them was explored. The average auricle parameters were calculated. The scatter plot showed a linear relationship between auricle length and auricle surface area (R2 = 0.9913), which demonstrated that the auricle area was approximately equal to the auricle length multiplied by 76.921. Additionally, the surface area of the expanders was measured and made into a table for selection against the surface area of the auricles. Using our equation, the auricle surface could be estimated by simply measuring the non-defective auricle length; therefore, the suitable volume of the expander could be determined.



Author(s):  
Ned Block

According to conceptual role semantics (CRS), the meaning of a representation is the role of that representation in the cognitive life of the agent, for example, in perception, thought and decision-making. It is an extension of the well-known ‘use’ theory of meaning, according to which the meaning of a word is its use in communication and, more generally, in social interaction. CRS supplements external use by including the role of a symbol inside a computer or a brain. The uses appealed to are not just actual, but also counterfactual: not only what effects a thought does have, but what effects it would have had if stimuli or other states had differed. Of course, so defined, the functional role of a thought includes all sorts of causes and effects that are non-semantic, for example, perhaps happy thoughts can bolster one’s immunity, promoting good health. Conceptual roles are functional roles minus such non-semantic causes and effects. The view has arisen separately in philosophy (where it is sometimes called ‘inferential’ or ‘functional’ role semantics) and in cognitive science (where it is sometimes called ‘procedural semantics’).



1998 ◽  
Vol 274 (1) ◽  
pp. L26-L31 ◽  
Author(s):  
Paul J. Jagielo ◽  
Timothy J. Quinn ◽  
Nilofer Qureshi ◽  
David A. Schwartz

To further determine the importance of endotoxin in grain dust-induced inflammation of the lower respiratory tract, we evaluated the efficacy of pentaacylated diphosphoryl lipid A derived from the lipopolysaccharide of Rhodobacter sphaeroides (RsDPLA) as a partial agonist of grain dust-induced airway inflammation. RsDPLA is a relatively inactive compound compared with lipid A derived from Escherichia coli (LPS) and has been demonstrated to act as a partial agonist of LPS-induced inflammation. To assess the potential stimulatory effect of RsDPLA in relation to LPS, we incubated THP-1 cells with RsDPLA (0.001–100 μg/ml), LPS (0.02 μg endotoxin activity/ml), or corn dust extract (CDE; 0.02 μg endotoxin activity/ml). Incubation with RsDPLA revealed a tumor necrosis factor (TNF)-α stimulatory effect at 100 μg/ml. In contrast, incubation with LPS or CDE resulted in TNF-α release at 0.02 μg/ml. Pretreatment of THP-1 cells with varying concentrations of RsDPLA before incubation with LPS or CDE (0.02 μg endotoxin activity/ml) resulted in a dose-dependent reduction in the LPS- or CDE-induced release of TNF-α with concentrations of RsDPLA of up to 10 μg/ml but not at 100 μg/ml. To further understand the role of endotoxin in grain dust-induced airway inflammation, we utilized the unique LPS inhibitory property of RsDPLA to determine the inflammatory response to inhaled CDE in mice in the presence of RsDPLA. Ten micrograms of RsDPLA intratracheally did not cause a significant inflammatory response compared with intratracheal saline. However, pretreatment of mice with 10 μg of RsDPLA intratracheally before exposure to CDE (5.4 and 0.2 μg/m3) or LPS (7.2 and 0.28 μg/m3) resulted in significant reductions in the lung lavage concentrations of total cells, neutrophils, and specific proinflammatory cytokines compared with mice pretreated with sterile saline. These results confirm the LPS-inhibitory effect of RsDPLA and support the role of endotoxin as the principal agent in grain dust causing airway inflammation.



2020 ◽  
pp. 229255032093367
Author(s):  
Paul Yen ◽  
Marija Bucevska ◽  
Christopher Reilly ◽  
Cynthia Verchere

Introduction: We hypothesize that treatment of significant truncal lesions with truncal tissue expanders and subsequent flap surgery in pediatric patients may increase the risk of scoliosis. This study aims to investigate any relationship between tissue expansion (TE) and scoliosis and to compare the prevalence of scoliosis in our tissue expander population to the general population. Methods: Health records of patients who underwent truncal TE at BC Children’s Hospital between 1997 and 2017 were retrospectively reviewed and analyzed. The cross-sectional component of the study consisted of radiological imaging to establish the presence or absence of scoliosis. Results: We identified 28 patients who underwent truncal TE over the study period. Ten had a scoliosis X-ray on their chart or as a part of the study. Three (10.7%) patients were identified as having developed scoliosis after TE. Conclusions: We recommend that pediatric TE patients be made aware of the potential complication of scoliosis and be followed closely in the years during and after their treatment, in order to allow for preventative measures, early diagnosis and early management (if required).



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