Radiation-induced modification of secondary metabolites contents in plants of Salvia officinalis L. and Silybum marianum L.

Aim. Long-term studies of the effect of sublethal doses of pre-sowing low-LET ionizing radiation on seeds have demonstrated the effectiveness of radiation biotechnology to stimulate the accumulation of pharmaceutically valuable secondary metabolites in medicinal raw materials of a number of common medicinal plants in Ukraine. The aim of this research was to evaluate the effectiveness of radiation technology in the case of seeds of Salvia officinalis L. and Silybum marianum L. Methods. X-ray irradiation of seeds at doses up to 50 Gy, spectrophotometric analysis of water-ethanol extracts, fluorescence microscopy of leaf epidermis were used. Results. Doses of pre-sowing X-ray irradiation were selected which maximally stimulate both the increase of biomass of medicinal raw materials and the accumulation of secondary metabolites. In particular for Salvia officinalis L. doses are 5 Gy and 20 Gy, for Silybum marianum L. are 10 Gy and 20 Gy. Conclusions. It is recommended to use two stimulating doses at the same time, as the result of exposure depends essentially on the physiological status of the seeds, growing conditions, varietal characteristics. Increasing the content of flavonoids and phenols in medicinal raw materials has been shown to be a reliable and reproducible marker of stimulating of rosemary acid accumulation in Salvia officinalis leaves. Keywords: radiation-induced stimulation, Salvia officinalis, Silybum marianum, rosemary acid, silibinin.

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Effect of phosphorus uptake on growth and secondary metabolites of garden sage (Salvia officinalis L.)

Journal of the Science of Food and Agriculture ◽

10.1002/jsfa.3561 ◽

2009 ◽

Vol 89 (6) ◽

pp. 1090-1096 ◽

Cited By ~ 72

Author(s):

Monika Nell ◽

Marlies Vötsch ◽

Horst Vierheilig ◽

Siegrid Steinkellner ◽

Karin Zitterl-Eglseer ◽

...

Keyword(s):

Secondary Metabolites ◽

Phosphorus Uptake ◽

Salvia Officinalis ◽

Salvia Officinalis L

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Comparative Quantitative Analysis of Diterpene Acids in Raw Material of Salvia officinalis, Salvia tesquicola and Salvia nutans

International Journal of Pharmacognosy and Phytochemical Research ◽

10.25258/phyto.v9i07.11154 ◽

2018 ◽

Vol 9 (07) ◽

Author(s):

Kurkin V A ◽

Ryzhov V. M. ◽

Shmygareva A. A. ◽

Nikandrova M. A.

Keyword(s):

Quantitative Analysis ◽

Related Species ◽

Raw Materials ◽

Salvia Officinalis ◽

Raw Material ◽

Minimal Amount ◽

Closely Related Species ◽

Diterpene Acids ◽

Salvia Officinalis L

The quantitative analysis of diterpene acids in raw materials of closely related species of genus Salvia was carried out. The objects of present research were Salvia officinalis L., Salvia tesquicola Klokov and Pobed., Salvia nutans L., which grow in neighboring south (Samara and Orenburg) regions. During analysis different raw materials, such as herbs and leaves, were studied. It was determined that total amount of diterpene acids varies from 1,04% to 1,32% in leaves of different species of Salvia and from 1,13% to 1,67% in herbs of different species of Salvia. The raw material of Salvia nutans contains minimal amount of diterpene acids, but in the raw material of Salvia tesquicola the quantitative analysis shows different results, which depend on the region. The medical raw material of Salvia officinalis, which is cultivated in Samara region, includes sufficient amount of diterpene acids.

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NMR studies and X-ray crystallography of galdosol 5-methyl ether from Salvia officinalis L.

Journal of Crystallographic and Spectroscopic Research ◽

10.1007/bf01161344 ◽

1992 ◽

Vol 22 (5) ◽

pp. 585-590 ◽

Cited By ~ 1

Author(s):

Z. Djarmati ◽

R. M. Jankov ◽

J. Csanadi ◽

A. Djordjević ◽

B. Ribar ◽

...

Keyword(s):

Methyl Ether ◽

Salvia Officinalis ◽

Nmr Studies ◽

X Ray ◽

X Ray Crystallography ◽

Salvia Officinalis L

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Growth regulator and microfertilizers on Sage (Salvia officinalis L.) and Greater Burdock (Arctium lappa L.): effectiveness of complex application

VEGETABLE CROPS OF RUSSIA ◽

10.18619/2072-9146-2020-4-79-83 ◽

2020 ◽

pp. 79-83

Author(s):

N. I. Kovalev ◽

G. P. Pushkina

Keyword(s):

Growth Regulator ◽

Field Experiments ◽

Foliar Application ◽

Raw Materials ◽

Salvia Officinalis ◽

Aromatic Plants ◽

Medicinal And Aromatic Plants ◽

Arctium Lappa ◽

The Russian Federation ◽

Salvia Officinalis L

Relevance.Meeting the needs of the pharmaceutical industry with domestic medicinal raw materials is relevant. Methods.The aim of the study is to determine the effectiveness application by growth regulator, organomineral and microfertilizers on Sage (Salvia officinalis L.) and Greater Burdock (Arctium lappa L.) in conditions of Non-chernozem zone of the Russian Federation. The experimental part of the work was performed in Institute of Medicinal and Aromatic Plants in 2010-2011 and 2016-2017 by field experiments. On burdock we tested fertilizer Siliplant (0.5 l / ha): the first treatment was in the rosette phase, the second - after 20 days. On sage studied binary mixture of organomineral fertilizer EcoFys (1 l / ha) with fertilizer Zitovit (0.5 l / ha; applied in phase regrowth of plants) with following foliar application by complex microfertilizers Siliplant (0.5 l / ha) and growth regulator Zircon (40 ml / ha). The solution consumption is 300 l / ha.Results. The effectiveness of chelated form micro-fertilizers and organomineral fertilizers applied on various medicinal plants was shown. It has been established, that complex application by EcoFys+Zitovit (I treatment) and microfertilizer Siliplant with growth regulator Zircon (II treatment) can increase the productivity of Sage: yield of grass raised by 23%, roots by 40%. Similar results were obtained on the Greater Burdock culture – treatment of plants with microfertilizer Siliplant allowed to increase the yield of roots by 28%, leaves-by 24%.

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Comparison of antioxidant and antimicrobial activities of extracts obtained from Salvia glutinosa L. and Salvia officinalis L.

Hemijska industrija ◽

10.2298/hemind110412034v ◽

2011 ◽

Vol 65 (5) ◽

pp. 599-605 ◽

Cited By ~ 11

Author(s):

Dragan Velickovic ◽

Ivana Karabegovic ◽

Sasa Stojicevic ◽

Miodrag Lazic ◽

Valentina Marinkovic ◽

...

Keyword(s):

Essential Oil ◽

Plant Material ◽

Aqueous Ethanol ◽

Raw Materials ◽

Antimicrobial Activities ◽

Salvia Officinalis ◽

Plant Materials ◽

Salvia Officinalis L ◽

Extracting Solvent ◽

Antioxidant And Antimicrobial Activities

Antioxidant and antimicrobial activities as well as total phenols and flavonoids contents of Salvia glutinosa L. (glutinous sage) and Salvia officinalis L. (sage) extracts were studied. Methanol and aqueous ethanol (70% v/v) were used for extraction of bioactive compounds, both in the presence and the absence of ultrasound, from herb and the spent plant material remaining after the essential oil hydrodistillation. The ratio of plant material to extracting solvent was 1:10 g/ml. Antioxidant and antimicrobial activities of the extracts were found to depend on the type of plant material and the extraction conditions. The plant materials from which essential oil had been recovered were proven to be valuable raw materials for making various herbal preparations.

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EVALUATION OF SECONDARY METABOLITES VARIATION IN MEDICINAL PLANTS AND OPTIMIZATION OF SAGE (SALVIA OFFICINALIS L.) GROWTH IN VITRO

Chemical Technology ◽

10.5755/j01.ct.64.2.6021 ◽

2014 ◽

Vol 64 (2) ◽

Author(s):

A. Ramanauskas ◽

I. Jonuškienė

Keyword(s):

Medicinal Plants ◽

Secondary Metabolites ◽

Salvia Officinalis ◽

Salvia Officinalis L

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Development of technology for obtaining a liquid extract of medicinal sage ( Salvia officinalis L.)

BIO Web of Conferences ◽

10.1051/bioconf/20214003004 ◽

2021 ◽

Vol 40 ◽

pp. 03004

Author(s):

Anastasia Moldavanova ◽

Anastasia Malyutina ◽

Larissa Kozubova ◽

Valentina Kazakova ◽

Natalia Shestopalova

Keyword(s):

Inflammatory Diseases ◽

Raw Materials ◽

Extraction Process ◽

Salvia Officinalis ◽

Raw Material ◽

Optimal Time ◽

Processing Plant ◽

Plant Materials ◽

Liquid Extract ◽

Salvia Officinalis L

Inflammatory diseases of the female genital area are dominant among the total number of gynecological diseases. Among all the variety of medicinal plant materials used in official medicine, salvia medicinal draws attention to itself, which has repeatedly proved its effectiveness in the treatment of inflammatory diseases of the mucous membranes of various origins. That is why the goal was set to develop a technology for obtaining a liquid extract from the leaves of Salvia officinalis L. As a result of the study, a method was developed for obtaining a liquid extract by selecting the optimal extraction conditions. It was found that the optimal raw material-extractant ratio is 1:50, the optimal concentration of the extractant ethyl alcohol is 70%, the infusion time of the extract is 24 hours. To intensify the extraction process, the method of ultrasonic processing of raw materials at the soaking stage was used. The optimal time for processing plant materials with ultrasound was 45 minutes. As a result of using this method to obtain a liquid extract from the leaves of sage officinalis, the yield of phenolic compounds was doubled in comparison with obtaining an extract without sonication of raw materials and amounted to 182.7 mg / g of flavonoids in terms of luteolin-7-glycoside.

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Effectiveness of complex application of organomineral fertilizer EcoFus with the growth regulator Zircon on sage (Salvia officinalis L.)

VEGETABLE CROPS OF RUSSIA ◽

10.18619/2072-9146-2019-6-76-79 ◽

2019 ◽

pp. 76-79

Author(s):

N. I. Kovalev ◽

E. L. Malankina

Keyword(s):

Essential Oil ◽

Growth Regulator ◽

Field Experiments ◽

Raw Materials ◽

Salvia Officinalis ◽

Aromatic Plants ◽

Medicinal And Aromatic Plants ◽

Experimental Part ◽

The Russian Federation ◽

Salvia Officinalis L

Relevance. Meeting the needs of the pharmaceutical industry with essential oil raw materials and natural essential oils is relevant.Methods. The aim of the study is to determine the effectiveness the complex application by organomineral fertilizer EcoFys and the growth regulator Zircon on sage (Salvia officinalis L.) in conditions of Non-chernozem zone of the Russian Federation. The experimental part of the work was performed in Institute of Medicinal and Aromatic Plants in 2014-2015 by field experiments.Results. It has been established, that integrated application EcoFys and Zircon can increase yield of culture. In addition, it is shown that contain of essential oil in medicinal raw don’t increase and raising collection of essential oil provides only due to higher yield of herb.

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