A multicentre cross-sectional descriptive study evaluating the cardiovascular risk profile of preoperatively identified patients with hypertension

Abstract Background Chronic auto-inflammatory diseases are associated with an increased risk of arterial and venous cardiovascular diseases (CVD). Pathogenesis may be related to chronic inflammation and/or traditional CVD risk factors. We aimed to assess the prevalence of CVD and cardiovascular risk profile in inflammatory bowel disease (IBD), psoriasis (PSO) and spondylarthropathies (SpA). Methods This is a single center cross-sectional study at the depts. of Gastroenterology, Dermatology and Rheumatology. Patients ≥18 years underwent body measurements (blood pressure (BP), BMI, waist and hip circumference), laboratory analysis (plasma glucose, lipid spectrum) and completed a cardiovascular questionnaire (e.g. history of CVD, medication use). Multivariate linear and logistic regression models corrected for age and sex were applied to identify differences between groups.. Sensitivity analyses were performed excluding patients taking statins or anti hypertensive drugs. Within groups, association between lipid levels and clinical disease activity was assessed by stratification, and with CRP levels by Pearson correlation test. Results A total of 668 patients were included (335 males (50%), median age 47 years: 459 IBD (69%), 106 PSO (16%) and 103 SpA patients (15%). (Table 1) The prevalence of venous thromboembolisms was 6%, heart failure 3% and arterial CVD 8%. IBD patients had lower BMI, systolic BP, TC and LDL-c levels, and lower odds ratio of having diabetes, overweight and hypercholesterolemia, as compared to PSO and SpA, but a higher odds ratio of having VTE. (Table 2) These results were independent of statin of anti hypertensive drug use. All groups showed a trend towards higher levels of TC, HDL-c and LDL-c during disease remission as compared to active disease (Figure 1) Overall, TC and LDL-c levels were inversely correlated with CRP (R -.145, p=.002 and R -.111, p=.016); within groups a significant association was only observed in IBD. (Table 3, Figure 2) Conclusion IBD patients have a more favorable cardiovascular risk profile, as compared to PSO and SpA. Screening and early intervention for CVD risk factors requires different strategies for each population.

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Cardiovascular risk profile of high school students: A cross-sectional study

Revista Portuguesa de Cardiologia (English Edition) ◽

10.1016/j.repce.2014.01.026 ◽

2014 ◽

Vol 33 (9) ◽

pp. 525-534

Author(s):

Teresa Rocha ◽

Evangelista Rocha ◽

Ana Catarina Alves ◽

Ana Margarida Medeiros ◽

Vânia Francisco ◽

...

Keyword(s):

High School ◽

High School Students ◽

Cardiovascular Risk ◽

Cross Sectional Study ◽

Risk Profile ◽

Cardiovascular Risk Profile ◽

Sectional Study ◽

School Students ◽

Cross Sectional

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The cardiovascular risk profile in patients with inflammatory bowel disease: A cross-sectional single center study (The care-IBD study)

Atherosclerosis ◽

10.1016/j.atherosclerosis.2020.10.793 ◽

2020 ◽

Vol 315 ◽

pp. e251-e252

Author(s):

J.A.M. Sleutjes ◽

J. E. Roeters Van Lennep ◽

P.J.P. Verploegh ◽

C.J. Van Der Woude ◽

A.C. De Vries

Keyword(s):

Inflammatory Bowel Disease ◽

Cardiovascular Risk ◽

Bowel Disease ◽

Risk Profile ◽

Cardiovascular Risk Profile ◽

Single Center ◽

Cross Sectional ◽

Single Center Study ◽

Inflammatory Bowel ◽

Center Study

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Vegetarian, pescatarian and flexitarian diets: sociodemographic determinants and association with cardiovascular risk factors in a Swiss urban population

British Journal Of Nutrition ◽

10.1017/s0007114520001762 ◽

2020 ◽

Vol 124 (8) ◽

pp. 844-852

Author(s):

Hannah Wozniak ◽

Christophe Larpin ◽

Carlos de Mestral ◽

Idris Guessous ◽

Jean-Luc Reny ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Population Based ◽

Risk Profile ◽

Lower Income ◽

Cardiovascular Risk Profile ◽

Cross Sectional ◽

Sociodemographic Determinants ◽

Vegetarian Diets

AbstractPrevalence and trends of different vegetarian diets remain unknown, with estimates varying depending on the source. Evidence suggests that vegetarian diets are associated with a more favourable cardiovascular risk profile. The present study aimed to assess the prevalence and trends of different types of vegetarian diets in a population-based representative sample, sociodemographic characteristics of participants following such diets and the association of these diets with cardiovascular risk factors. Using repeated cross-sectional population-based surveys conducted in Geneva, Switzerland, 10 797 individuals participated in the study between 2005 and 2017. Participants were classified as vegetarians, pescatarians, flexitarians or omnivores using an FFQ. Sociodemographic and cardiovascular risk factors were evaluated through questionnaires, anthropometric measurements and blood tests. Findings show prevalence of vegetarians increased from 0·5 to 1·2 %, pescatarians from 0·3 to 1·1 % and flexitarians remained stable at 15·6 % of the population over the study period. Compared with omnivores, vegetarians were more likely to be young (OR 2·38; 95 % CI 1·01, 5·6), have higher education (OR 1·59; 95 % CI 1·01, 2·49) and lower income (OR 1·83; 95 % CI 1·04, 3·21); pescatarians and flexitarians were more likely to be women (pescatarian: OR 1·81; 95 % CI 1·10, 3·00; vegetarian: OR 1·57; 95 % CI 1·41, 1·75) and flexitarians were also more likely to have a lower income (OR 1·31; 95 % CI 1·13, 1·53). Participants who adhered to any diet excluding/reducing meat intake had lower BMI, total cholesterol and hypertension compared with omnivores. The present study shows an increase in the prevalence of vegetarians over a 13-year period and suggests that the different vegetarian diets assessed are associated with a better cardiovascular risk profile.

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P5312Sleep duration and carotid atheromatic burden. Insights from the Corinthia study

European Heart Journal ◽

10.1093/eurheartj/ehz746.0283 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

E Oikonomou ◽

S Tsalamandris ◽

G Vogiatzi ◽

G Lazaros ◽

E Christoforatou ◽

...

Keyword(s):

Cardiovascular Risk ◽

Carotid Artery ◽

Sleep Duration ◽

Atherosclerotic Plaque ◽

Intima Media Thickness ◽

Risk Profile ◽

Cardiovascular Risk Profile ◽

Cross Sectional ◽

Atherosclerotic Burden ◽

Adjacent Segments

Abstract Background Sleep is an essential physiological process and disturbance of sleeping pattern may be associated with cardiovascular risk profile and atheromatosis. Short but also long sleep duration (LSD) may be adversely affect cardiovascular parameters. Purpose To study how sleep duration is associated with cardiovascular risk profile and carotid atherosclerotic burden. Methods Corinthia study is a cross sectional epidemiological study based on 2043 inhabitants (age 40–99 years) of Corinthia region in Greece. Ultrasonography was used to measure intima media thickness (IMT) in the left and right common carotid artery, carotid bulb and internal carotid artery. The mean IMT (meanIMT) were determined as representative values of carotid atherosclerosis burden. Thickness of IMT>1.5 mm or protrusion >50% compared to adjacent segments was considered as atherosclerotic plaque. Based on questionnaires of Corinthia study, total sleeping time per day was recorded. A sleep duration of 7 to 8 h was consider normal (NSD), sleep duration <6 h was consider very short (VSSD), 6–7 h sleep duration was considered short (SSD) and participants with >8 h sleep duration was categorized as LSD. Results Concerning gender more men than women were categorized in the NSD (26% vs. 21%, p<0.001). Subjects in the NSD were also younger compared to subjects categorized in other sleeping patterns (VSSD: 66±12 y vs. SSD: 63±12 y vs. NSD: 62±12 y vs. LSD: 66±12 y, p<0.001), have less prevalence of diabetes mellitus (p<0.05). There was no difference according to sleeping pattern in body mass index, prevalence of hypertension, cardiovascular disease, hyperlipidemia and on current smoking habits according to sleeping patterns. Interestingly, meanIMT (VSSD: 1.08±0.51 mm vs. SSD: 0.97±0.42 mm vs. NSD: 0.97±0.41 mm vs. LSD: 1.14±1.64 mm, p=0.04) and carotid atherosclerotic plaque (VSSD: 35% vs. SSD: 25% vs. NSD: 20% vs. LSD: 30%, p=0.006) was decreased in NSD subjects. Importantly, even after adjustment for the confounders logistic regression analysis revealed that subjects in the NSD group have 50% less odds of carotid atheromatic plaque than subjects in the VSSD (Odds ratio: 0.5, 95% CI 0.28–0.90, p=0.02) (Figure). Conclusion A balanced sleeping pattern with 8h of sleep daily can act as an additive cardioprotective factor in the modern western type societies. Short especially less than 6 hours and long (>8 hours) sleeping duration may act as a cardiovascular risk factor.

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