Ozone therapy as complementary treatment for surgical infection: case report.

Background: Infection is a serious surgical complication that increases significantly morbidity and mortality rates as well as health care expenses. Bacterial ever-growing resistance to antibiotics makes the treatment of such events even more troublesome. Objective: Report on a surgical infection case treated with ozone as a complementary therapy. Methods and Materials: Female, 65 years old, submitted to a complex surgical procedure for adult kyphotic deformity correction that presented with early post-surgical infection. The patient was treated with revision surgery and antibiotics that improved the condition but were unable to delete the infection. Ozone, in its gaseous form, was injected subcutaneously and paravertebraly twice weekly for three weeks. Results: After 3 weeks of treatment the wound healed completely and repeated visits and blood exams up to one year after the surgery did not show recurrence of infection. Conclusions: Although not a definite indication on validity of ozone therapy for surgical infections, the results of this case report indicate a new way that merits to be explored.

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Pyoderma Gangrenosum Following the Revision of a Breast Reconstruction and Abdominoplasty

The Open Dermatology Journal ◽

10.2174/1874372201408010068 ◽

2014 ◽

Vol 8 (1) ◽

pp. 68-71 ◽

Cited By ~ 3

Author(s):

Mio Nakamura ◽

Amir M. Ghaznavi ◽

Vigen Darian ◽

Aamir Siddiqui

Keyword(s):

Case Report ◽

Breast Reconstruction ◽

Pyoderma Gangrenosum ◽

Breast Augmentation ◽

Surgical Complication ◽

Aesthetic Surgery ◽

Skin Response ◽

Clinical Consequences ◽

One Year ◽

Dermatologic Disease

Pyoderma gangrenosum (PG) is a rare ulcerative dermatologic disease and little is known about its etiology and pathogenesis. Recent reports show that there have been limited but increasing number of cases of PG following aesthetic surgeries. Post-surgical PG is often misdiagnosed, which can have serious clinical consequences. The following case report describes a young woman who underwent a cosmetic breast augmentation and abdominoplasty which was complicated by post-operative necrotizing fasciitis. She was presented one year later for surgical correction of her acquired breast and abdominal deformities. Post-operatively she developed a severe inflammatory skin response presumed to be a wound infection. However, after repeated surgical debridements, the wounds persisted without a defined bacterial or fungal organism. After clinical exclusion of all other etiologies, PG was diagnosed and confirmed with histopathology. The patient was subsequently treated with aggressive immunosuppressive therapy, and the lesions resolved without any signs of residual PG. This case report attempts to increase awareness for the rare post-surgical complication of PG in aesthetic surgery and to improve future diagnosis and management of such cases.

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One-Year Morbidity and Mortality Rates Associated with Clipping Unruptured Intracranial Aneurysms

10.1055/s-0039-1679762 ◽

2019 ◽

Author(s):

Khodayar Goshtasbi ◽

Ronald Sahyouni ◽

Alice Wang ◽

Edward Choi ◽

Gilbert Cadena ◽

...

Keyword(s):

Intracranial Aneurysms ◽

Mortality Rates ◽

Morbidity And Mortality ◽

Unruptured Intracranial Aneurysms ◽

One Year

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1497-P: Secular Trends in Incidence and One-Year Mortality Rates of Lower Extremity Amputation in People with Diabetes in Hong Kong between 2001 and 2016

Diabetes ◽

10.2337/db20-1497-p ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 1497-P

Author(s):

HONGJIANG WU ◽

AIMIN YANG ◽

ERIC S. LAU ◽

RONALD C. MA ◽

ALICE P. KONG ◽

...

Keyword(s):

Hong Kong ◽

Lower Extremity ◽

Mortality Rates ◽

Secular Trends ◽

Lower Extremity Amputation ◽

One Year ◽

Extremity Amputation

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Search for Promising Strains of Probiotic Microbiota Isolated from Different Biotopes of Healthy Cats for Use in the Control of Surgical Infections

Pathogens ◽

10.3390/pathogens10060667 ◽

2021 ◽

Vol 10 (6) ◽

pp. 667

Author(s):

Pavel Rudenko ◽

Yuriy Vatnikov ◽

Nadezhda Sachivkina ◽

Andrei Rudenko ◽

Evgeny Kulikov ◽

...

Keyword(s):

Antimicrobial Agents ◽

High Efficiency ◽

Biological Marker ◽

High Sensitivity ◽

Antagonistic Activity ◽

Adhesive Properties ◽

Surgical Infection ◽

Surgical Infections ◽

Causative Agents ◽

Inflammatory Processes

Despite the introduction of modern methods of treatment, the creation of new generations of antibacterial agents, and the constant improvement of aseptic and antiseptic methods, the treatment of purulent–inflammatory processes remains one of the most complex and urgent problems in veterinary practice. The article presents the results of the isolation of indigenous microbiota from various biotopes of healthy cats, as well as the study of their biological marker properties for the selection of the most optimal strains in probiotic medicines for the control of surgical infections. It was demonstrated that isolated cultures of bifidobacteria and lactobacilli, which we isolated, revealed high sensitivity to antibiotics of the β-lactam group (excepting L. acidophilus No. 24, L. plantarum “Victoria” No. 22, L. rhamnosus No. 5, L. rhamnosus No. 20, and L. rhamnosus No. 26, which showed a significant variability in sensitivity to antibacterial drugs of this group, indicating the great potential of these microorganisms) and resistance to aminoglycosides, lincosamides, and fluoroquinolones (with the exception of gatifloxacin, which showed high efficiency in relation to all lactic acid microorganisms). The adhesive properties of the isolated lactobacteria and bifidobacteria were variable, even within the same species. It was found that the B. adolescentis No. 23 strain of the Bifidobacterium genus, as well as the L. plantarum No. 8, L. plantarum “Victoria” No. 22, L. rhamnosus No. 6, L. rhamnosus No. 26, L. acidophilus No. 12, and L. acidophilus No. 24 strains of the Lactobacillus genus had the highest adhesive activity. Thus, when conducting a detailed analysis of the biological marker properties of candidate cultures (determining their sensitivity to antimicrobial agents, studying the adhesive properties, and antagonistic activity in relation to causative agents of surgical infection in cats), it was found that the most promising are L. plantarum “Victoria” No. 22, L. rhamnosus No. 26, and L. acidophilus No. 24.

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Efficacy of biostimulatory ozone therapy: case report and literature review

Journal of Cosmetic Dermatology ◽

10.1111/jocd.14079 ◽

2021 ◽

Author(s):

Ricardo Grillo ◽

Adrienne Coelho Lacerda ◽

Tarley Eloi Pessoa de Barros ◽

Cláudio Roberto Pacheco Jodas ◽

Rubens Gonçalves Teixeira

Keyword(s):

Case Report ◽

Literature Review ◽

Ozone Therapy

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Corneal cross-linking for treatment of progressive keratoconus in a patient with Alport syndrome: A case report

European Journal of Ophthalmology ◽

10.1177/1120672121997672 ◽

2021 ◽

pp. 112067212199767

Author(s):

Iva Krolo ◽

Aida Kasumović ◽

Ivana Radman ◽

Pavao Pavić

Keyword(s):

Case Report ◽

Alport Syndrome ◽

Contact Lenses ◽

Corneal Dystrophy ◽

Clinical Findings ◽

Cross Linking ◽

Posterior Polymorphous Corneal Dystrophy ◽

One Year ◽

Corneal Tomography

Purpose: Ocular features of Alport syndrome include anterior lenticonus, posterior polymorphous corneal dystrophy, and fleck-and-dot retinopathy in most cases. Keratoconus in such patients has been rarely mentioned in previous studies. To our knowledge, this is the first report of corneal cross-linking for halting the progression of keratoconus in a patient with Alport syndrome. Case report: A 22-year-old male was referred for his initial corneal topography, after he was already prescribed with rigid gas-permeable contact lenses. Alport syndrome was diagnosed in his infancy and gene COL4A5 mutation was confirmed. Ophthalmological evaluation confirmed keratoconus. One-year follow-up showed a progression on his right eye and standard corneal cross-linking was performed. Stabilization of the disease marked by normalization in visual function and corneal tomography values was noticed 1 year after the procedure. Conclusions: When diagnosing ocular clinical findings of Alport syndrome, keratoconus should be considered. Standard corneal cross-linking protocol can halt its progression.

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Impact of the period of the day on mortality and major cardiovascular complications after vascular surgeries

European Heart Journal ◽

10.1093/ehjci/ehaa946.3213 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Author(s):

F.A.M Cardozo ◽

T Artioli ◽

B Caramelli ◽

D Calderaro ◽

P.C Yu ◽

...

Keyword(s):

Multivariable Analysis ◽

Total Mortality ◽

Mortality Rates ◽

Cardiovascular Complications ◽

Cardiac Complications ◽

Funding Source ◽

Confounding Variables ◽

Significant Difference ◽

One Year ◽

Night Period

Abstract Introduction Patients submitted to arterial vascular surgeries are at a high risk of postoperative cardiac and non-cardiac complications, therefore developing strategies to lower perioperative complications is essential to optimize outcomes for this subgroup. Recent studies have suggested that the period of the day in which surgeries are performed may influence postoperative major cardiovascular complications but there is still no evidence of this association in vascular surgeries. Purpose Our goal is to evaluate whether the period of the day in which surgeries are performed may influence mortality and cardiovascular outcomes in patients undergoing non-cardiac vascular procedures. Methods Patients who underwent non-cardiac vascular surgeries between 2012 and 2018 were prospectively included at our cohort. For this analysis, subjects were categorized into two groups: those who underwent surgery in the morning (7am - 12am) and those who underwent surgery in the afternoon/night (12:01pm - 6:59am). The primary endpoints were to compare the incidence of major adverse cardiac events (MACE - acute myocardial infarction, acute heart failure, arrhythmias, and cardiovascular death) and total mortality between morning and afternoon/night surgeries within 30 days and one year. The secondary endpoint was the incidence of perioperative myocardial injury (PMI) in both groups. PMI was defined as an absolute elevation of high-sensitivity cardiac troponin T (hs-cTnT) concentrations ≥14ng/L. Multivariable analysis using Cox proportional regression (with Hazard Ratio – HR and Confidence Interval – 95% CI) was performed to adjust for confounding variables, including emergency and urgent surgeries. Results Of 1267 patients included, 1002 (79.1%) underwent vascular surgery in the morning and 265 (20.9%) in the afternoon/night. After adjusting for confounding variables, the incidence of MACE at 30 days was higher among those who underwent surgery in the afternoon/night period (37.4% vs 20.4% – HR 1.43, 95% CI: 1.10–1.85; p=0.008). Mortality rates were also elevated in the afternoon/night group (21.5% vs 9.9%, HR 1.59, 95% CI: 1.10–2.29; p=0.013). After one-year of follow-up the worst outcomes persisted in patients operated in the afternoon/night: higher incidence of MACE (37.7% vs 21.2%, HR 1.37, 95% CI: 1.06–1.78; p=0.017) and mortality (35.8% vs 17.6%, HR 1.72, 95% CI 1.31–2.27; p<0.001). There was no significant difference in the incidence of PMI between groups (p=0.8). Conclusions In this group of patients, being operated in the afternoon/night period was independently associated with increased mortality rates and incidence of MACE. Mortality and MACE at one year Funding Acknowledgement Type of funding source: Foundation. Main funding source(s): FAPESP - Fundação de Amparo a Pesquisa do Estado de São Paulo

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Quadruple Disruption of the Superior Shoulder Suspensory Complex (SSSC) and Outcome after One Year of Conservative Treatment: A Case Report

journal of Clinical & Experimental Orthopaedics ◽

10.4172/2471-8416.100013 ◽

2016 ◽

Vol 02 (01) ◽

Author(s):

Felix Toft ◽

Fabrizio Moro

Keyword(s):

Case Report ◽

Conservative Treatment ◽

One Year

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Acute Disseminated Encephalomyelitis Associated with Pasteurella multocida Meningitis

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100053440 ◽

2003 ◽

Vol 30 (2) ◽

pp. 155-158 ◽

Cited By ~ 9

Author(s):

Normand L. Proulx ◽

Mark S. Freedman ◽

James W. Chan ◽

Baldwin Toye ◽

Cathy C. Code

Keyword(s):

Case Report ◽

Antibiotic Treatment ◽

Pasteurella Multocida ◽

Clinical Course ◽

Acute Disseminated Encephalomyelitis ◽

Persistent Fever ◽

Mri Scans ◽

One Year ◽

Culture Positive ◽

Serial Mri

ABSTRACT:Objective:To describe a case of Pasteurella multocida meningitis associated with acute disseminated encephalomyelitis (ADEM).Case report:A 33-year-old woman employed in a dog pound presented herself to hospital with fever and meningismus and was found to have culture positive Pasteurella multocida meningitis. Despite appropriate antibiotic treatment her clinical course was characterized by a persistent fever and worsening encephalopathy, which prompted further neurological investigation. Spinal fluid exam and serial MRI scans as well as her one-year clinical course were found to be compatible with ADEM.Conclusion:Persistent fever and worsening encephalopathy in meningitis may indicate a para-infectious immune process such as ADEM, and may serve as indications for further neurological investigation.

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