scholarly journals In-vitro Assessment of Effectiveness and Photostability Avobenzone in Cream Formulations by Combination Ethyl Ascorbic acid and alpha Tocopherol Acetate

Author(s):  
Marline Abdassah ◽  
Ratih Aryani ◽  
Emma Surachman ◽  
Muchtaridi Muchtaridi
1995 ◽  
Vol 38 (15) ◽  
pp. 2880-2886 ◽  
Author(s):  
J. Martin Grisar ◽  
Gilbert Marciniak ◽  
Frank N. Bolkenius ◽  
Joelle Verne-Mismer ◽  
Eugene R. Wagner

Open Medicine ◽  
2006 ◽  
Vol 1 (1) ◽  
pp. 23-34
Author(s):  
Anna Gorąca ◽  
Beata Skibska

AbstractSerum contains various antioxidant molecules that may provide important protection against free radical attack. The aim of this work was to assess the total antioxidant capacity of plasma and a marker of lipid per oxidation [(thiobarbituric acid-reactive substances (TBARS)] in plasma of healthy smoking and non-smoking young and elderly subjects. In addition, we investigated plasma concentrations of α-tocopherol, β-carotene, and ascorbic acid. In in vitro experiments, the effects of exogenous compounds (ascorbic acid, uric acid, Trolox) on total ferric-reducing activity of plasma (FRAP) were also tested. We demonstrated that total antioxidant capacity of plasma obtained from healthy non-smoking young subjects was significantly higher than plasma antioxidant capacity of smoking elderly subjects. The concentration of TBARS in young non-smoking volunteers was lower than that in young smokers. The concentration of TBARS in elderly non-smoking volunteers was lower than in elderly smokers. Plasma concentrations of alpha-tocopherol, beta-carotene and ascorbic acid were significantly lower in elderly smoker than in elderly non-smokers of the same age. No difference in the plasma levels of alpha-tocopherol, beta-carotene and ascorbic acid were found in 22-year-old smoking and non-smoking subjects. In vitro addition of ascorbic acid, uric acid, or Trolox to plasma samples significantly increased their total antioxidant capacity. Decrease of FRAP values and increase of TBARS concentrations is a significant physiologic condition of the aging process. Supplementation of antioxidants could be useful for the enhancement of antioxidant screen in plasma.


2012 ◽  
Vol 48 (No. 1 - 2) ◽  
pp. 33-40 ◽  
Author(s):  
O. Kucuk ◽  
N. Sahin ◽  
K. Sahin ◽  
Gursu MF ◽  
F. Gulcu ◽  
...  

This experiment was conducted to evaluate the effects of vitamin C (L-ascorbic acid) and vitamin E (α-tocopherol acetate) on egg production, egg quality, lipid peroxidation status (measured as MDA), and some serum metabolites in laying hens (Hy-Line) maintained at a low ambient temperature (6°C). One hundred and twenty laying hens (18-wk-old) were divided into four groups, 30 hens per group. The laying hens were fed either a basal diet or the basal diet supplemented with either 250 mg of L-ascorbic acid/kg of diet, 250 mg of α-tocopherol acetate/kg of diet or 250 mg of L-ascorbic acid plus 250 mg of α-tocopherol acetate/kg of diet. Although feed consumption of the hens was similar (P > 0.05) among treatments, supplemental vitamin C and E significantly increased final body weight, egg production, and improved feed efficiency (P < 0.05). Egg weights were also greater (P < 0.05) in hens supplemented with the combination of vitamin C and E than that of hens supplemented either vitamin or no vitamin (control). Haugh unit did not change upon each vitamin supplementation, but the combination of the vitamin supplement yielded a higher Haugh unit (P < 0.05). Each dietary supplement of vitamin C and vitamin E improved the egg quality (P < 0.05) resulting in a greater specific gravity, thicker egg shell, and heavier egg shell weight. Separately or as a combination, supplemental vitamin C and E decreased MDA, glucose, cholesterol, and triglyceride concentrations (P < 0.05). Results of the present study showed that supplementing vitamin C and vitamin E, particularly as a combination, improved the performance of cold-stressed laying hens, offering a potential protective management practice in preventing cold stress-related losses in performance of laying hens. Results of the present study also indicated that the effects of vitamin C and vitamin E are additive.


2005 ◽  
Vol 40 (2) ◽  
pp. 93-97 ◽  
Author(s):  
G Dalvit ◽  
SP Llanes ◽  
A Descalzo ◽  
M Insani ◽  
M Beconi ◽  
...  

2000 ◽  
Vol 84 (3) ◽  
pp. 261-267 ◽  
Author(s):  
Iona M. J. Hamilton ◽  
William S. Gilmore ◽  
Iris F. F. Benzie ◽  
Clive W. Mulholland ◽  
J. J. Strain

Despite convincingin vitroevidence, a vitamin C–E interaction has not been confirmedin vivo. This study was designed to examine the effects of supplementation with either vitamin C or E on their respective plasma concentrations, other antioxidants, lipids and some haemostatic variables. Fasting blood was collected before and after intervention from thirty healthy adults in a double-blinded crossover study. Baselines for measured variables were established after 2 weeks of placebo supplementation, followed by daily supplementation with 73·5 mgRRR-α-tocopherol acetate or 500 mg ascorbic acid, and placebo, for 6 weeks. A 2 month washout preceded supplement crossover. Mean values showed that plasma lipid standardised α-tocopherol increased with ascorbic acid supplementation: from 4·09 (SEM 0·51) TO 4·53 (sem 0·66) μmol/mmol total cholesterol plus triacylglycerol (P< 0·05), and plasma ascorbic acid increased from 62·8 (sem 14·9) to 101·3 (sem 22·2) μmol/l (P< 0·005). Supplementation with (RRR)-α-tocopherol acetate increased plasma α-tocopherol from 26·8 (sem 3·9) to 32·2 (sem 3·8) μmol/l (P< 0·05), and lipid-standardised α-tocopherol from 4·12 (sem 0·48) to 5·38 (sem 0·52) μmol/mmol (P< 0·001). Mean plasma ascorbic acid also increased with vitamin E supplementation, from 64·4 (sem 13·3) to 76·4 (sem 18·4) μmol/l (P< 0·05). Plasma ferric reducing (antioxidant) power and glutathione peroxidase (U/g haemoglobin) increased in both groups, while urate, total cholesterol and triacylglycerol levels decreased (P< 0·05 throughout). Results are supportive of anin vivointeraction between vitamins C and E.


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