scholarly journals Variants in Circadian Rhythm Gene Cry1 Interacts with Healthy Dietary Pattern for Serum Leptin Levels: a Cross-sectional Study

2021 ◽  
Vol 10 (1) ◽  
pp. 48
Author(s):  
Hadith Tangestani ◽  
Hadi Emamat ◽  
Mir Saeed Yekaninejad ◽  
Seyed Ali Keshavarz ◽  
Khadijeh Mirzaei
2020 ◽  
Author(s):  
Maria Norburg Tell ◽  
Katarina Hedin ◽  
Mats Nilsson ◽  
Marie Golsäter ◽  
Hans Lingfors

Abstract BackgroundDietary pattern early in life is to some degree preserved into adulthood and may have implications for future health. There is scarce knowledge on associations between choices of certain foods among adolescents. The aim of this study was to explore how intakes of different food groups, correspond to each other from a health perspective among adolescents. MethodsThis cross-sectional study used data from 16-year-olds (n=13 451), who completed a health questionnaire within School Health Services from 2009 until 2015, in a county from Southern Sweden. Dietary pattern based on the response-alternatives from the ten items regarding intake of food and food frequency intake were grouped as healthy, moderately healthy, and unhealthy intakes, based on Nordic Nutrition Recommendations. ResultsIn the student cohort healthy reported intakes of different healthy food groups were closely connected to each other. Association between intakes of certain food groups were seen. High intake of fish, vegetables and fruit were associated to each other, as well as low intake of sweet drinks, sweets and snacks. The highest association was seen between high intake of fruit and high intake of vegetables, with OR=23 (95% CI 12 to 44).ConclusionHealthy food intakes were associated with each other among 16-year-old adolescents; High intake of fruit and vegetables could serve as a key indicator for a healthy dietary pattern in this age group. This knowledge increases the understanding of food patterns among adolescents and can be used for designing interventions. It also raises a hypothesis that focusing on offering healthy foods, more than restricting unhealthy foods could have a positive impact on the dietary pattern.


2020 ◽  
Author(s):  
Maria Norburg Tell ◽  
Katarina Hedin ◽  
Mats Nilsson ◽  
Marie Golsäter ◽  
Hans Lingfors

Abstract The authors have withdrawn this preprint from Research Square.


2002 ◽  
pp. 505-511 ◽  
Author(s):  
C Rolf ◽  
S von Eckardstein ◽  
U Koken ◽  
E Nieschlag

INTRODUCTION: In healthy men, body weight and total fat content increase with advancing age, while serum testosterone levels decrease. In order to elucidate whether a causal relationship between these phenomena exists, we investigated the influence of testosterone or human chorionic gonadotrophin substitution on body mass index (BMI), total fat mass and serum leptin in testosterone-treated and untreated hypogonadal patients in comparison with ageing eugonadal men. METHODS: In a cross-sectional study, the inter-relationships of body weight, total fat mass, serum sex hormones and leptin were analysed in untreated hypogonadal men (n=24; age 19-65 years), treated hypogonadal men (n=61; age 20-67 years) and healthy eugonadal men (n=60; age 24-78 years). Total fat mass was assessed by bioimpedance measurement. Univariate and multiple linear regression analysis was used to detect possible differences. RESULTS: In eugonadal men, serum testosterone levels decreased with advancing age (correlation coefficients: r=-0.71; P<0.0001), while BMI (r=0.39; P=0.002), total fat content (r=0.51; P<0.0001) and leptin (r=0.48; P<0.0001) increased significantly. In untreated hypogonadal patients, an increase in BMI (r=0.50; P=0.013) and total fat mass (r=0.41; P=0.044) was also observed with advancing age. However, in substituted hypogonadal patients, no age-dependent change in BMI (r=0.067; P=0.606), body fat content (r=-0.083; P=0.522), serum testosterone (r=-0,071; P=0.59) or serum leptin (r=-0.23; P=0.176) was found. CONCLUSION: Since testosterone-substituted older hypogonadal men show BMI and fat mass similar to those of younger eugonadal men and since non-treated hypogonadal men are similar to normal ageing men, testosterone appears to be an important factor contributing to these changes. Thus ageing men should benefit from testosterone substitution as far as body composition is concerned.


2019 ◽  
pp. 155982761987192
Author(s):  
Maryam S. Hamidi ◽  
Tait D. Shanafelt ◽  
Andrea Hausel ◽  
Bryan D. Bohman ◽  
Rachel Roberts ◽  
...  

There is increasing evidence that diet can mitigate fatigue. The objective of this study was to assess the associations between dietary habits and sleep-related impairment (SRI) in a cohort of community physicians. In this cross-sectional study, we analyzed data from 245 physicians who had completed a wellness survey in March 2016 (98% response rate). Three dietary patterns were derived using principal component analysis: plant based, high protein, and high saturated fat and sugar. In the adjusted analysis, every SD increase in the plant-based dietary pattern score was associated with a 0.71-point decrease ( β = −0.72; SE = 0.32; P = .027; 95% CI = −1.35 to −0.08) in the SRI score, and every SD increase in the high saturated fat and sugar dietary pattern score was associated with a 0.77-point increase ( β = 0.77; SE = 0.32; P = .015; 95% CI = 0.15 to 1.39) in the SRI score. There were no associations between high protein diets and SRI scores. Physicians adhering to diets that are high in plant-based foods and low in saturated fat and added sugars had less SRI. Physicians currently face significant barriers to maintaining a healthy diet. This study highlights the potential role of workplace nutrition on SRI and work performance of physicians.


Author(s):  
Grasiane Izidorio GARBELLOTTO ◽  
Fernanda Jardim REIS ◽  
Ana Maria Pandolfo FEOLI ◽  
Carla Haas PIOVESAN ◽  
Andréia da Silva GUSTAVO ◽  
...  

ABSTRACT Background: Actually the lifestyle exposes the population to several risk factors related to alimentary habits and less physical activity that contributes to chronic diseases appearance worldwide. Aim: To analyze the association between salivary cortisol and the components of metabolic syndrome. Methods: This is a cross-sectional study. As part of it, 28 individuals aged 30-59 years presenting three or more of the following findings: CA: ≥88 cm for women and ≥102 cm for men; SBP>130 mmHg and DBP>85 mmHg; GL>100 mg/dl; TG>150 mg/dl; HDL<40 mg/dl for men and <50 mg/dl for women. Was performed analysis of salivary cortisol (by radioimmunoassay) from 25 salivary samples collected throughout the day, for evaluating changes in the circadian rhythm of this hormone (8AM, noon and 8PM). Results: 28 evaluated individuals had a mean age of 51.9±7.5 years, mostly women (64.3%) and a mean of BMI 33.6±3.2 kg/m². The cortisol level from the 8AM averaged 18.7±4.8 ng/dlL. Individuals with FPG>110mg/dl, have significantly lower average levels of cortisol than ones with FPG <110 (12.8±5,2 vs. 17.3±4.2). Significant correlations were HOMA vs. WC (r=0,465; p˂0,005) and TG (r=0,473; p˂0,005), WC vs. FG (r=0,446; p˂0,005) and BMI (r=0,730; p˂0.0001); TG vs. HDL (r=0,441 p˂0,005) and FG (r=0,440; p˂0,005). Conclusion: Morning salivary cortisol in subjects with chronically elevated blood glucose can represent a downregulation of the hypothalamic-pituitary adrenal axis. This is an important finding not yet well investigated.


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