scholarly journals Direct-Push Blood Transfusion Practice in the Neonatal Unit of a Tertiary Hospital in South-South, Nigeria

2021 ◽  
pp. 91-96
Author(s):  
E. U. Bassey ◽  
S. B. Adesina
Keyword(s):  
Blood Transfusion ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Tertiary Hospital ◽  
Transfusion Practice ◽  
Hospital Data ◽  
Direct Push ◽  
Before And After ◽  
Aseptic Conditions ◽  
Blood Bag

Introduction: Transfusion of blood is a life-saving intervention in the care of ill neonates. Donated blood is a scarce national resource and must be used in the most efficient way. Exchange blood transfusion using the blood bag is the commonest mode of blood delivery employed. Other modalities of safe and sustainable blood delivery should also be explored, especially where paucity of funds predominates. This study aims to assess the usefulness of the direct push method where applicable, as an alternative to blood bag delivery in neonatal units of resource poor settings. Methods: A two year retrospective study of newborns admitted in the neonatal wards of the University of Uyo Teaching Hospital. Data obtained were the age, gender, indication for admission, packed cell volume (PCV) before and after transfusion. Blood transfusion was done in aliquots over 24 hours under aseptic conditions, via a peripheral vein. The push and pull method was employed, with no anticoagulant in the syringe. Post-transfusion PCV was done at least 24 hours after the procedure. Results: Of the one thousand and seventy-seven (1077) admitted neonates, two hundred and thirty-nine (22.2%), received blood products. Of these, twenty-one (8.8%), received a direct whole blood transfusion. Age (days) of the neonates transfused ranged from 1 to 26 days, with a mean of 10.4 ± 8.13. The Packed Cell Volume (PCV) pre-transfusion ranged between 20% - 44%, with a mean of 30.05 ± 6.39 while post-transfusion PCV ranged between 31% to 51%, with a mean of 38.17 ± 5.52(Fig. 1). The commonest indication for transfusion was prematurity, 9(42.8%) and neonatal sepsis 5 (23.8%). Conclusion: The direct transfusion of blood occasionally used, seems a relatively safe practice to correct mild/moderate anaemia. It also provides sufficient blood, with the advantage of usage when the umbilical cord access is no longer feasible and where cost of blood would otherwise, hinder quick intervention. This practice may need further evaluation by other centers.

scholarly journals Evaluation and Correlation of Hepcidin-25 Hormone, Hemoglobin and Packed Cell Volume of Patients With β-Thalassaemia Intermedia Before and After Blood Transfusion for Iraqi Children Patients

2018 ◽  
Vol 31 (3) ◽  
pp. 70
Author(s):  
Mohammed Q. Saadoon ◽  
Bushra H. Ali
Keyword(s):  
Blood Transfusion ◽  
Iron Overload ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Affected Person ◽  
Before And After ◽  
Thalassaemia Trait ◽  
Thalassaemia Intermedia ◽  
Compound Heterozygotes ◽  
Control Samples

            β-thalassaemia consists of 3 chief forms: thalassaemia primary (other called "cooley's Anaemia" or "Mediterranean durability Anaemia"), thalassaemia intermedia or thalassaemia minor also frequent termed "β-thalassaemia carrier", "β-thalassaemia trait" however, "heterozygous β-thalassaemia". separately from the rare magisterial forms, problem along β-thalassaemia essential are homozygotes or made heterozygotes because B0 and B+ genes, problem including thalassaemia intermedia are typically homozygotes and compound heterozygotes then subjected with thalassaemia minor are broadly heterozygotes. In this study, we take eighty humans the age about them had been mean±SD (9.68±2.08), 40 patients along β-thalassaemia intermedia, then 40 healthy people as much control. extraction gore 5ml from thalassaemia's patients before gore transfusion then afterwards take the blood  by way of three days. The samples we instituted are 120, forty samples before blood transfusion, 40 samples after gore transfusion then 40 control samples. Then we separated every pattern of twin's tubes. Amplify blood attention about β-thalassaemia intermedia patient since blood advancement due according to minimize degree regarding hepcidin-25 further than its instruction was once shown up iron focus meanly affect through hepcidin-25 level, therefore so hepcidin-25 used to be surprisingly significant exchange in β-thalassaemia intermedia affected person afterwards blood advancement yet so much conduct to iron overload. So  we conclude low level of Hemoglobin before and after blood transfusion due to decrease or absent formation of β-globin that because gene disorder, and conclude correlation between hepcidin hormone with Hb and PCV. The aim of this study is to evaluate hepcidin-25 levels, hemoglobin [Hb] and packed cell volume [PCV] before and after blood transfusion, then correlation of hepcidin-25 hormone with [Hb] and [PCV] of children patients with β-thalassaemia intermedia.

scholarly journals Blood Transfusion Practice before and after Implementation of Type and Screen Protocol in Emergency Department of a University Affiliated Hospital in Iran

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Mostafa Alavi-Moghaddam ◽  
Mahmoud Bardeh ◽  
Hossein Alimohammadi ◽  
Habib Emami ◽  
Seyed-Mostafa Hosseini-Zijoud
Keyword(s):  
Emergency Department ◽  
Blood Transfusion ◽  
Transfusion Practice ◽  
Time Interval ◽  
Blood Transfusions ◽  
Common Diseases ◽  
Before And After ◽  
Transfusion Ratio ◽  
Cross Match

Background. Blood transfusion is the cornerstone of therapy for many serious and common diseases. This study was performed to assess blood transfusion practice before and after implementation of type and screen protocol in emergency department of a university affiliated hospital in Iran, 2012-2013.Methods. An audit was studied before and after the implementation of type and screen protocol. The number of blood transfusions, time interval between blood order and transfusion, cross-match to transfusion ratio (C/Tratio), and transfusion index (TI) were checked.C/Tratio was used as a measure of the efficiency of blood ordering practice. We compared our results before and after implementation of type and screen protocol.Results. In present study after implementation of type and screen protocol, the time interval between requesting blood transfusion and transfusion of blood has decreased significantly (P<0.001). The number of blood transfusions required by actual patients increased significantly from 1/2 to 2 (P<0.001). The average cross-match to transfusion (C/T) ratio got near 1.13 from 1.41 and TI got near 0.91 from 0.58 (P<0.001).Conclusion. The implementation of T&S protocol has been proven to be safe, efficient, and beneficial to the transfusion practice of our hospital from the current study.

scholarly journals Effect of Halothane and Enflurane Anaesthesia on the Level of Reduced Glutathione in Human Red Blood Cells

1980 ◽  
Vol 8 (3) ◽  
pp. 356-358 ◽  
Author(s):  
N. S. Agar ◽  
G. B. H. Lewis
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Blood Cells ◽  
Reduced Glutathione ◽  
Haemoglobin Concentration ◽  
Red Cell ◽  
Anaesthetic Agents ◽  
Human Red Blood Cells ◽  
Enflurane Anaesthesia ◽  
Before And After

No significant changes were found in packed cell volume, haemoglobin concentration and red cell glutathione levels in patients before and after anaesthesia with halothane or enflurane. These results, though unable to explain the mechanism, support the earlier suggestion that glutathione plays little, if any, role in protecting liver against toxic effects of these anaesthetic agents or their metabolites.

scholarly journals BLOOD PROFILES OF GREEN SEA TURTLE BEFORE AND AFTER THE REHABILITATION

2020 ◽  
Vol 9 (6) ◽  
pp. 930-939
Author(s):  
Ida Bagus Windia Adnyana ◽  
Ida Bagus Nararya Primastana Adnyana ◽  
Siswanto Siswanto
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Haemoglobin Concentration ◽  
Chelonia Mydas ◽  
Sea Turtle ◽  
Corpuscular Haemoglobin ◽  
Turtle Conservation ◽  
Before And After ◽  
Mean Corpuscular Haemoglobin ◽  
Corpuscular Haemoglobin Concentration

Penyu adalah satwa yang terancam punah, sehingga upaya konservasinya perlu ditingkatkan. Kegiatan yang berhubungan dengan konservasi dimaksud adalah rehabilitasi penyu pascamengalami periode out of the water sebelum dilepasliarkan kembali ke alam bebas. Penelitian ini bertujuan untuk mengetahui perbedaan profil dan indeks eritrosit penyu hijau (Chelonia mydas) sebelum dan sesudah mengalami rehabilitasi di Turtle Conservation and Education Center (TCEC) di Pulau Serangan, Denpasar. Penelitian ini menggunakan sampel Sembilan ekor penyu hijau hasil sitaan Polisi Sektor Kuta, Badung, Bali. Sebanyak 2,5 mL darah perifer penyu hijau diambil dari sinus cervicalis dorsalis disimpan di tabung berisikan antikoagulan litium heparin dan dilanjutkan dengan pemeriksaan hematologi. Penentuan nilai total eritrosit dihitung dengan hemositometer. Kadar hemoglobin (Hb) diukur menggunakan Hemoglobinometer Sahli, sedangkan kadar Packed Cell Volume (PCV) ditentukan dengan metode mikrohematokrit. Indeks eritrosit yang meliputi Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH) dan Mean Corpuscular Haemoglobin Concentration (MCHC) dihitung dengan rumus konvensional yang ditentukan untuk itu. Data hasil penelitian dianalisis secara deskriptif kuantitatif menggunakan uji T berpasangan. Nilai profil darah (Packed Cell Volume, total eritrosit, Hemoglobin) mengalami peningkatan signifikan pasca rehabilitasi dengan nilai rerata hematokrit sebelum rehabilitasi sebesar 28,4±3,09 menjadi 31,7±2,87, nilai total eritrosit sebelum rehabilitasi sebesar 0,44±0,10 menjadi 0,56±0,15, nilai Hemoglobin sebelum rehabilitasi sebesar 6,3±1,28 menjadi 7,53±0,73 serta hasil perhitungan secara statistika dengan uji T-berpasangan menunjukkan profil darah penyu hijau sebelum dan sesudah rehabilitasi memiliki perbedaan yang signifikan yang berarti proses rehabilitas yang dilakukan di Turtle Conservation and Education Center, Serangan berhasil.

Comparison of blood transfusion practice in two hospitals before and after publication of evidence of acceptable haemoglobin levels

2001 ◽  
Vol 18 (Supplement 21) ◽  
pp. 57
Author(s):  
J. Kinsella ◽  
G. Fletcher ◽  
M. Garrioch ◽  
T. Walsh ◽  
M. Daniel ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Transfusion Practice ◽  
Before And After

Blood Requests and Utilization in Elective Surgical Patients in a Nigerian Teaching Hospital

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S168-S168
Author(s):  
A T Olatinwo ◽  
A Bolarinwa ◽  
T Adeyemo
Keyword(s):  
Blood Transfusion ◽  
Tertiary Hospital ◽  
Transfusion Practice ◽  
Surgical Patients ◽  
Surgical Interventions ◽  
Elective Surgical Procedures ◽  
Blood Transfusion Service ◽  
One Year ◽  
Transfusion Ratio ◽  
Transfusion Guidelines

Abstract Introduction/Objective Although requesting for blood is a very common practice for patients for surgical interventions, the average requirement for a particular procedure is usually based on subjective anticipation of blood loss rather than on evidence based estimates. Over-ordering of blood components results in wasting of technical time, reagents and imposes extra cost on patients. The objective of this study is to assess blood ordering and utilization in a Nigerian Tertiary Hospital. Methods A review of one year data collected from the records of all discharged surgical patients and blood bank registers was done. Blood utilization was calculated using crossmatch to transfusion ratio (C/T), transfusion probability (%T), and transfusion index (TI). Results A crossmatch request for 1,228 units for 569 patients was made. Requests was higher for gynaecological cases (24.8 %) followed by orthopaedic procedures and least for cardiothoracic and urological surgeries (1.4 % each). Out of the crossmatched units, 880 units was transfused for 373 patients. The overall of C/T, %T, and TI were 1.4, 65.6%, and 1.55 respectively. The highest C/T was observed in elective caesarean sections (2.25) and neurosurgeries (2.2) while the lowest C/T was observed in oral maxillofacial surgeries (1.09) Conclusion Unnecessary crossmatching with minimal transfusion practice was observed in many elective surgical cases. Blood request pattern for elective surgeries needs to be revised and unnecessary requests minimized. There is a need for a Hospital blood transfusion committee which should come up with blood request policies and transfusion guidelines for elective surgical procedures and also conduct regular blood transfusion service audits.

scholarly journals Malaria Seroprevalence in the Blood Donors of Malaria Endemic Regions of Northern Andhra Pradesh, India.

2020 ◽  
Vol 6 (8) ◽  
pp. 493-497
Author(s):  
Dr. C. Sitalata ◽  
◽  
Dr. K. Kalyan ◽  
Keyword(s):  
Blood Transfusion ◽  
Andhra Pradesh ◽  
Blood Donors ◽  
Blood Donation ◽  
Transfusion Practice ◽  
Test Results ◽  
Blood Safety ◽  
Medical Sciences ◽  
Endemic Areas ◽  
Blood Bag

Introduction: Transmission of malaria through blood transfusion continues to be a major threat tosafe blood transfusion practice. Transfusion-transmitted malaria occurs at an estimated rate of 0.25cases per 1 million blood units collected. It is significantly more common in endemic areas. Aim: Tostudy the Seroprevalence of Malaria among the blood donors in the endemic areas of NorthernAndhra Pradesh. Materials and methods: The present survey was carried out at the blood bank ofMaharaja institute of medical sciences, Vizianagaram. This includes the analysis of seroprevalence ofMalaria in the blood donors during the period of 1 year from February 2018 to January 2019. Two mlof the blood sample was collected in the labeled pilot tube at the time of collection of blood fromdonor tubing of the blood bag. The serum was separated. The samples were tested for Malaria byrapid antigen detection test. Results: Out of the total of 3096 blood donors, replacement donors(86.91%) were more in comparison to voluntary donors (13.08%). The seroprevalence among thereplacement blood donors was more compared to voluntary blood donors. Conclusion: Voluntaryblood donation, increasing awareness about blood donation in the general population, selection ofrepeat, non-remunerated, regular voluntary blood donors and diligent donor selection, sensitivescreening tests are most important to increase blood safety and prevent transmission of Malariathrough blood transfusion.

scholarly journals Implementation and Effectiveness of a Bar Code–Based Transfusion Management System for Transfusion Safety in a Tertiary Hospital: Retrospective Quality Improvement Study

10.2196/14192 ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. e14192 ◽  
Author(s):  
Shin-Shang Chou ◽  
Ying-Ju Chen ◽  
Yu-Te Shen ◽  
Hsiu-Fang Yen ◽  
Shu-Chen Kuo
Keyword(s):  
Quality Improvement ◽  
Blood Transfusion ◽  
Large Scale ◽  
Tertiary Hospital ◽  
Patient Identification ◽  
Transfusion Therapy ◽  
Process Maps ◽  
Bar Code ◽  
Before And After ◽  
Product Verification

Background Large-scale and long-term studies are not sufficient to determine the efficiency that IT solutions can bring to transfusion safety. Objective This quality-improvement report describes our continuous efforts to implement and upgrade a bar code–based transfusion management (BCTM) system since 2011 and examines its effectiveness and sustainability in reducing blood transfusion errors, in a 3000-bed tertiary hospital, where more than 60,000 prescriptions of blood transfusion are covered by 2500 nurses each year. Methods The BCTM system uses barcodes for patient identification, onsite labeling, and blood product verification, through wireless connection to the hospital information systems. Plan-Do-Study-Act (PDSA) cycles were used to improve the process. Process maps before and after implementation of the BCTM system in 2011 were drawn to highlight the changes. The numbers of incorrect labeling or wrong blood in tube incidents that occurred quarterly were plotted on a run chart to monitor the quality changes of each intervention introduced. The annual occurrences of error events from 2011 to 2017 were compared with the mean occurrence of 2008-2010 to determine whether implementation of the BCTM system could effectively reduce the number of errors in 2016 and whether this reduction could persist in 2017. Results The error rate decreased from 0.03% in 2008-2010 to 0.002% in 2016 (P<.001) and 0.001% in 2017 (P<.001) after implementation of the BTCM system. Only one incorrect labeling incident was noted among the 68,324 samples for blood typing, and no incorrect transfusions occurred among 67,423 transfusion orders in 2017. Conclusions This report demonstrates that continuous efforts to upgrade the existing process is critical to reduce errors in transfusion therapy, with support from information technology.

scholarly journals Profil Darah dan Nilai Hematologi Domba Lokal yang Dipelihara di Hutan Pendidikan Gunung Walat Sukabumi

2008 ◽  
Vol 8 (2) ◽  
pp. 1-8
Author(s):  
D.A. Astuti ◽  
D.R. Ekastuti ◽  
Y. Sugiarti ◽  
Marwah Marwah
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Blood Protein ◽  
Feeding Time ◽  
Total Blood ◽  
Eating Time ◽  
Haematological Values ◽  
Hypochromic Anaemia ◽  
Significant Difference ◽  
Before And After

Blood profil and hematological status of local sheep under the gunung walat education forest area SukabumiABSTRACT. Gunung Walat Education Forest (HPGW) is one of special forest which integrated with farm system (Agrosilvopastural). This forest is heterogeneous which dominated with agathis, damar and pinus trees. To support the farming system is needed basic data haematology and blood profil of sheep that lived in HPGW. This research was aimed to evaluate haematological values covering Red Blood Cell, haemoglobin, Packed Cell Volume, MCV, MCH, MCHC and blood nutrient profil of lambs and ewes fed with mixed grass which is grow surrounding HPGW. Evaluation were done on 5 productive ewes and 5 male lambs 5-6 month ages, before and after eating time. The result showed that RBC of the lamb was (7.57 0.40) x 106/mm3 and for ewes was (5.71 0.05) x 106/mm3. Hb of lamb was (7.21 0.27) g/100ml and for ewes was (6.62 0.54) g/100ml, PCV of lamb was (28.10 7.21) % and ewes was (26.80 3.42) %, MCV of lamb was (32.68 1,23) fl and ewes was (50.91 1.53) fl, MCH of lamb was (10.82 0.47) pg and ewes was (12.93 0.29) pg, MCHC of lamb was (27,53 4.70)% and for ewes was (25.54 1.57) %. There were no significant difference on haematological values before and after feeding time except for Packed Cell Volume (P 0.05). The clinical result showed that lambs was suffering normocytic hypochromic anaemia and adults was suffering macrocytic hypochromic anaemia. Glucose level and total blood protein were at normal level while blood triglyseride concentration was lower than normal ewes concentration. 

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