scholarly journals Retroperitoneal Primary Cystic Tumours: (Case Series of Seven Patients and Literature Review)

Author(s):  
Oussama Lafkihq ◽  
Saad Rifki El Jai ◽  
Erguibi Driss ◽  
Rachid Boufettal ◽  
Farid Chihab

Primary retroperitoneal cystic tumors include all cystic tumors that arise in the retro and sub peritoneal space independent of the kidney, the excretory tract, the adrenal gland, large vessels and contiguous viscera. We propose a retrospective study of 7 cases of primary retroperitoneal cystic tumors, collected in the department of digestive cancer surgery and liver transplantation at the Ibn Rochd University Hospital in Casablanca over a period of 10 years (2009 to 2019). Our patients are divided into 6 women and 1 man with an average age of 42 years. The diagnostic time varies from 3 months to 3 years with an average of 10 months. The revealing signs are mainly pain (7 cases or 100%) and abdominal mass (3 cases or 43%). The positive diagnosis is based on ultrasound (2 cases or 40%) but above all on computed tomography (7 cases or 100%) which specifies the retroperitoneal site as well as the relationship of the tumor to neighboring organs. Its confirmation can only be histological. Surgery with total resection is the treatment of choice.

2011 ◽  
Vol 23 (4) ◽  
pp. 867-879 ◽  
Author(s):  
Darlene Floden ◽  
Antonino Vallesi ◽  
Donald T. Stuss

The ability to step outside a routine—to select a new response over a habitual one—is a cardinal function of the frontal lobes. A large body of neuroimaging work now exists pointing to increased activation within the anterior cingulate when stimuli evoke competing responses (incongruent trials) relative to when responses converge (congruent trials). However, lesion evidence that the ACC is necessary in this situation is inconsistent. We hypothesized that this may be a consequence of different task procedures (context) used in lesion and neuroimaging studies. The present study attempted to reconcile the lesion and the fMRI findings by having subjects perform clinical and experimental versions of the Stroop task during BOLD fMRI acquisition. We examined the relationship of brain activation patterns, specifically within the anterior cingulate and left dorsolateral frontal regions, to congruent and incongruent trial types in different task presentations or contexts. The results confirmed our hypothesis that ACC activity is relatively specific to unblocked–uncued incongruent Stroop conditions that have not been used in large neuropsychological studies. Moreover, the size of the behavioral Stroop interference effect was significantly correlated with activity in ACC and left dorsolateral regions, although in different directions. The current results are discussed in terms of previous proposals for the functional roles of these regions in activating, monitoring, and task setting, and the relation of these findings to the disparate reports in recent case series is considered.


2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Yongxin Zheng ◽  
Haotian Lin ◽  
Wen Liu ◽  
Dandan Wang ◽  
Suying Huang

Purpose. To observe and classify vitreous incarcerations in patients undergoing second 20-gauge pars plana vitrectomy (PPV) for recurrent retinal detachment. Methods. Retrospective noncomparative consecutive case series. Eighty-two consecutive patients with recurrent retinal detachment were included. The previous sclerotomy sites were examined by our sclera depression method and the vitreous incarceration were classified into Grade 0–IV by their severity under surgical microscope before second surgery. The relationship of vitreous incarceration and different ports was statistically investigated in our included patients. Results. Vitreous incarceration in the previous sclerotomy sites were found frequently. Vitreous cutter sites were most involved, but the infusion pipe sites were the least. According to our classification and definition, Grade III and IV of vitreous incarceration in all the three different sclerotomy sites accounted for 32.5%. Grade II of vitreous incarceration consisted of 12.6%. Grade 0 and I in all the three different sclerotomy sites were 54.8%. The frequency of all grades of vitreous incarceration in light port or vitreous cutter port was significant higher than that in infusion port. Conclusions. Vitreous incarceration in light port and vitreous cutter port are found more common than in infusion port for 20-gauge PPV with our new method.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Sérgio Henrique Bastos Damous ◽  
Jones Pessoa dos Santos Junior ◽  
Álvaro Vicente Alvarez Pezzano ◽  
Mohamad Abdul Majid Chams ◽  
Nathaly Haritov ◽  
...  

Abstract Background Pneumomediastinum is a rare complication of COVID-19 pneumonia, which may or may not be associated with invasive ventilatory support. Therefore, the report and findings associated with its evolution can be of great contribution in the management of this unknown disease. Case presentation Here, we present a series of four patients with severe pneumomediastinum requiring intensive care unit. These patients developed pneumomediastinum before or during orotracheal intubation (OTI) or without OTI. The four patients were three men and one woman with a mean age of 60.5 years (48–74 years). No patients had a known history of lung disease or traumatic events, except for one patient who had a history of smoking, but who was without parenchymal disease. All intubations were performed without complications. No cases of pneumomediastinum occurred after tracheostomy, and none of the patients had tomographic or bronchoscopic evidence of tracheal injury. Although the pneumomediastinum observed in our cases was apparently not related to a violation of the aerodigestive track, this complication was associated with a worse prognosis. Conclusion Pneumomediastinum is a rare complication of COVID-19 pneumonia, and the most likely etiopathogenesis is severe pulmonary involvement, which may or may not be associated with invasive ventilatory support. Future studies with a greater number of cases should elucidate the relationship of pneumomediastinum to a probable prognostic factor.


2020 ◽  
Author(s):  
M Nishi ◽  
Mitsuo Shimada ◽  
Kozo Yoshikawa ◽  
Jun Higashijima ◽  
Takuya Tokunaga ◽  
...  

Abstract Background: CKLF-like MARVEL transmembrane domain containing 6 (CMTM6) is the master regulator of programmed cell death-ligand 1(PD-L1). We aimed to clarify the significance of CMTM6 expression in gastric cancer (GC). Methods: A total of 105 patients who had undergone curative surgical resection for stage II/III GC at Tokushima University Hospital were included in this study. The expression of CMTM and PD-L1 was examined by immunohistochemistry. Additionally, the relationship of each expression level to several prognostic factors was examined using univariate and multivariate analyses. Results: CMTM6 was not positively correlated with any of the factors examined. The overall survival (OS) rates were significantly poorer in the CMTM6 high-expression group than in the CMTM low-expression group (5-year OS: 57.2% vs. 79.2%, respectively; p<0.05). Disease-free survival (DFS) was significantly poorer in the CMTM high-expression group than in the CMTM6 low-expression group (5-year DFS: 52.8% vs. 72.4%, respectively; p=0.20). Multivariate analysis confirmed CMTM6 expression as an independent prognostic factor in DFS (p<0.05). CMTM6 expression tended to be correlated with PD-L1 expression (p=0.07), and PD-L1 expression was positively correlated with PD-1 expression (p<0.05).Conclusions: CMTM6 is associated with a poor prognosis and immunotolerance through PD-L1 in GC.


1986 ◽  
Vol 100 (3) ◽  
pp. 315-328 ◽  
Author(s):  
Shaukat Ali ◽  
Rammohan Tiwari ◽  
Gordon B. Snow ◽  
I. V.D. Waal

AbstractThe purpose of this paper is to define the incidence of squamous cell carcinoma (SCC) of the head and neck as seen at the Free University Hospital, Amsterdam, the Netherlands, in the last six years, according to the latest revised classification system of the International Union against Cancer (UICC, 1982). In addition, male to female ratios, relative frequencies at the various sites, age distribution, incidence of second or third primary and the relationship of distant metastases to the nodal metastases and the T-stage of the primary lesion are reported. These incidences are compared with those in other countries and the major differences are discussed.


2006 ◽  
Vol 13 (01) ◽  
pp. 133-137
Author(s):  
BUSHRA NAZIR ◽  
Muhammad Shamoon ◽  
Saifullah Sheikh ◽  
HINA AYESHA ◽  
Muhammad Tariq Bhatti

Objectives: To determine the relationship of etiology with the type ofcerebral palsy in children. Study Design: Descriptive case series. Setting: Department of Paediatrics, Allied Hospital,Faisalabad. Period: From January 2002 to December 2004. Patients and Methods: 120 children from 1-12 years ofage of either sex who presented in Paediatric Department with abnormalities of tone, posture and movement andsubsequently diagnosed as cerebral palsy on the basis of history, physical examination and investigations, wereincluded. Results: Out of 120 cases the majority had spastic CP, 72% (n = 86) such as quadriplegic, diplegic andhemiplegic types. The spastic quadriplegia was mainly associated with birth asphyxia and meningoencephalitis.Prematurity and low birth weight were the major contributors towards diplegic CP, while spastic hemiplegia althoughless common was caused by meningoencephalitis in 5 cases and intra cranial bleed and asphyxia in 3 cases each.Atonic or hypotonic CP found in 23 cases, were caused by meningoencephalitis, kernicterus, birth asphyxia andprematurity. 10 cases of atonic CP did not have any reason (hence idiopathic). Athetoid CP was mainly due tokernicterus, meningoencephalitis and asphyxia. Ataxic and mixed types of CP were present in 3 cases each and weredue to meningoencephalitis and birth asphyxia.


2012 ◽  
Vol 34 (1) ◽  
pp. 13-18 ◽  
Author(s):  
Lia Keuchguerian Silveira Campos ◽  
Anna Beatriz Ribeiro Ferreira Sampaio ◽  
Celso Garcia Junior ◽  
Ronis Magdaleno Junior ◽  
Maria Marta de Magalhães Battistoni ◽  
...  

INTRODUCTION: The complexity of factors involved in anorexia nervosa (AN) and the recommendations of prominent health organizations underscore the importance of reflecting on therapeutic interventions aimed at patients' family members. OBJECTIVE: To expand knowledge about the mother-daughter relationship in AN, with a focus on developing a conceptual framework that is able to improve the treatment of the disorder, reduce factors that perpetuate it and improve prognosis. METHOD: A clinical method, anchored by psychodynamic references, was employed in a group of family members of patients with eating disorders. The group met weekly, and sessions were led by psychologists from the eating disorder outpatient clinic of a university hospital. RESULTS AND DISCUSSION: Common characteristics in the mother-daughter relationship in cases of AN were identified. The issue of mutual control, the dialectic between omnipotence and impotence, and the relationship of devotion, passion and annihilation between mothers and daughters are phenomena that form the basis of AN, with a direct influence on the severity of each case and on treatment success. CONCLUSION: Our findings allowed us to identify important aspects in the mother-daughter relationship in AN, which may improve the clinical interventions aimed at treating the disorder.


2020 ◽  
pp. 019459982093865
Author(s):  
Ya-Lian Chen ◽  
Yang-Yang Bao ◽  
Shui-Hong Zhou ◽  
Hong-Tian Yao ◽  
Zhe Chen

Objective To measure pepsin expression in patients with vocal fold leukoplakia and elucidate its clinical significance. Study Design Retrospective analysis of pathologic archive specimens. Setting Affiliated university hospital. Subjects and Methods The study included 45 patients with vocal fold leukoplakia and 19 with vocal fold polyps who underwent surgical treatment between December 2013 and July 2016. Masses were detected on both vocal cords in 5 patients with vocal fold leukoplakia and in 1 patient with vocal fold polyps. Immunohistochemistry was used to assess pepsin expression. In addition, the relationship of pepsin expression level with clinical characteristics of vocal fold leukoplakia was assessed. Results The rate of pepsin expression was high in the polyp group (75%) and the leukoplakia group (68%); however, the difference between groups was not significant ( P > .05). Pepsin expression significantly increased according to grade of dysplasia (mild, 57.1%; moderate, 88.9%; severe, 100.0%; P = .034). Similarly, the percentage of lesions that exhibited strongly positive pepsin expression increased with the grade of dysplasia (mild, 37.1%; moderate, 66.7%; severe, 100.0%; P = .005). The leukoplakia recurrence rate was higher in patients with positive pepsin expression than in patients with negative pepsin expression but without a significant difference ( P > .05). Conclusion Our study suggests that pepsin was associated with the grade of dysplasia of vocal cord leukoplakia. Further investigation with appropriate control groups and controlling for other risk factors, such as smoking or alcohol consumption, is needed.


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