Clinico-pathological Profile of Pyogenic Liver Abscess: An Experience from Tertiary Care Hospital from Kashmir Valley

BACKGROUND Amoebic liver abscess is the commonest extra intestinal site of invasive amoebiasis which mainly affects infants and young children. The incidence of pyogenic liver abscess is much higher among children in developing countries than those in developed countries. Diagnosis of liver abscess can be challenging and is often delayed; a high index of suspicion is necessary in children with risk factors. Children have unique set of predisposing causes for liver abscesses. The purpose of this study was to assess the clinical, demographic, and etiological profile of liver abscess in children between 1 month to 12 years of age. METHODS This is a prospective observational study conducted in the Department of Pediatrics, Chacha Nehru Bal Chikistalaya (An Autonomous Institute under Govt. of NCT (National Capital Territory) of Delhi, affiliated to University of Delhi), Delhi from July 2016 to August 2017. All children aged 1 month to 12 years admitted with liver abscess (included consecutively) were enrolled after considering inclusion and exclusion criteria. Written and informed consent was taken from parents/guardians of children aged less than 7 years. Informed assent was taken from children aged more than 7 years, along with written and informed consent from their parents/guardians. Their clinical characteristics, radiological features and laboratory data were analysed. RESULTS Most common age group suffering from liver abscess was 5 - 10 years with male preponderance. Majority of the children belonged to lower socio-economic class and half of them were suffering from malnutrition. Most common clinical presentation of children suffering from liver abscess was fever with pain abdomen and tender hepatomegaly. Majority of the children had leucocytosis, high level of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Deranged liver function test with coagulopathy was noted in more than half of the children suffering from liver abscess. Commonest bacterial pathogen was methicillin resistant Staphylococcus aureus followed by Salmonella typhi, Stenotrophomonas maltophilia, coagulase negative Staphylococcus aureus and Staphylococcus hominis. Entamoeba histolytica is a common parasitic agent causing liver abscess in children. CONCLUSIONS Liver abscess should be considered in children presenting with fever and abdominal pain. Most cases involve a single lesion on right lobe of the liver. Methicillin resistant Staphylococcus aureus followed by Salmonella typhi are the two most common pathogens. KEYWORDS Paediatric Liver Abscess, Amoebic Liver Abscess, Pyogenic Liver Abscess, Children

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Clinical profile and management of pyogenic liver abscesses in a tertiary care hospital

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20195643 ◽

2019 ◽

Vol 8 (1) ◽

pp. 52 ◽

Cited By ~ 1

Author(s):

Shyam K. Gupta ◽

Ashufta Rasool ◽

Aamir H. Hela ◽

Rohit Goel ◽

Zahur Hussain

Keyword(s):

Liver Abscess ◽

Percutaneous Drainage ◽

Tertiary Care ◽

Management Strategies ◽

Standard Of Care ◽

Pyogenic Liver Abscess ◽

Modern World ◽

Care Hospital ◽

Medical College ◽

Liver Abscesses

Background: Pyogenic Liver abscesses are potentially life threatening if left untreated. They pose a major Diagnostic and therapeutic challenge to modern world. Interventional radiology is becoming standard of care for liver Abscesses.Methods: All patients of pyogenic liver abscess admitted to Government Medical College and hospital Jammu, J and K, India from October 2018 to November 2019 were prospectively studied. Demographics, presentation, lab reports and management strategies were evaluated.Results: Total of 60 patients of pyogenic liver abscesses were studied with 81.7% males. Alcohol was found to be most common risk factor with 55% of patients being alcoholic. Right lobe of liver was involved in 66.7% of patients. Segment VI and VII were involved in 50% of patients. The most common clinical symptom was right upper quadrant pain (98.3%), followed by fever (91.7%). The most common clinical sign was right upper quadrant tenderness (91.7%). Percutaneous drainage with catheter placement was the most common and successful modality of management associated with least hospital stay.Conclusions: Pyogenic liver abscess is a rare but serious problem. Early diagnosis and treatment are necessary to avoid mortality. Percutaneous drainage along with I.V antibiotics is the best form of management.

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EMERGENCY PERIPARTUM HYSTERECTOMY AT A TERTIARY CARE HOSPITAL IN KASHMIR VALLEY

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2015/61 ◽

2015 ◽

Vol 4 (03) ◽

pp. 400-407

Author(s):

Sameena Ashraf ◽

Yasmeen Gul ◽

Sadiq Malla M ◽

Ferkhand Mohiuddin Regoo

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Kashmir Valley ◽

Peripartum Hysterectomy ◽

Emergency Peripartum Hysterectomy

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Biomedical waste management practices at a paediatric tertiary care hospital of Kashmir valley

Indian Journal of Forensic and Community Medicine ◽

10.18231/2394-6776.2018.0053 ◽

2019 ◽

Vol 5 (4) ◽

pp. 231-235

Author(s):

Sheikh Mohd Saleem ◽

S Muhammad Salim Khan ◽

Mohsina Mukhtar ◽

Ruqia Quansar

Keyword(s):

Waste Management ◽

Management Practices ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Kashmir Valley ◽

Biomedical Waste ◽

Waste Management Practices

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Culture Sensitivity Patterns and Outcome of Liver Abscess in Children Admitted at a Tertiary Care Hospital in North India

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/635 ◽

2021 ◽

Vol 8 (41) ◽

pp. 3506-3512

Author(s):

Navya Sree Manugu ◽

Narayana Lunavath ◽

Ramu Pedada

Keyword(s):

Liver Abscess ◽

Tertiary Care ◽

Laboratory Data ◽

Pyogenic Liver Abscess ◽

Amoebic Liver Abscess ◽

Fungal Culture ◽

Care Hospital ◽

Sensitivity Pattern ◽

Culture Sensitivity ◽

Empirical Antibiotics

BACKGROUND Liver abscess has been recognised since the time of Hippocrates. Liver abscess is defined as collection of purulent material in liver parenchyma. They are usually caused by bacterial and amoebic infections, and less commonly, by other protozoal and helminthic organisms. Amoebic liver abscess is the commonest extra intestinal site of invasive amoebiasis which mainly affects infants and young children. The incidence of pyogenic liver abscess is much higher among children in developing countries than those in developed countries. The purpose of this study was to evaluate culture sensitivity pattern (Blood & Pus) of liver abscess in children. METHODS This prospective observational study was conducted in the Department of Paediatrics, Chacha Nehru Bal Chikistalaya, Delhi from July 2016 –to August 2017. This study has got Institutional Ethics Committee approval (Regd No: IEC/MAMC/78, Dt: 26/07/2016). All children aged 1 month to 12 years admitted with liver abscess (included consecutively) were enrolled after considering inclusion and exclusion criteria. Written and informed consent was taken from parents/guardians of children. Their clinical characteristics, radiological features, laboratory data, clinical management, and outcomes were analysed. RESULTS In our study, out of 70 patients, 3.2 % patients showed growth in the blood culture. Organsims isolated were Methicillin resistant Staphylococcus aureus (MRSA) 1.4 % (1), Salmonella typhi 1.4 % (1), staphylococcus coagulase negative 1.4 % (1). Out of 70 patients of liver abscess enrolled in the study, 36 patients underwent aspiration of pus from the abscess. Out of 36 aspirated cases, gram positive cocci was identified in 1 (1.4 %) patient. In our study, no acid fast bacilli was identified and no fungal culture showed growth of organism. Out of 70 cases of liver abscess, 10 were found to be amoebic liver abscess. In our study, all the 70 patients were started on empirical antibiotics. Out of 70 patients, surgical intervention was done in 36 patients. In our study all the patients were started on empirical antibiotics according to hospital protocol. CONCLUSIONS Liver abscess should be considered in children presenting with fever and abdominal pain. Organisms recovered from liver abscesses vary greatly. Surgical drainage has been the traditional mode of treatment of pyogenic liver abscess, but this was replaced by IV broad-spectrum antibiotics and imaging-guided percutaneous drainage. KEYWORDS Paediatric Liver Abscess, Amoebic Liver Abscess, Pyogenic Liver Abscess, Culture-Sensitivity, Children

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Biliary Ascariasis- Experience from a Tertiary Care Hospital in Kashmir Valley, India

Turkish Journal of Family Medicine & Primary Care ◽

10.5455/tjfmpc.180738 ◽

2015 ◽

pp. 1

Author(s):

Hanief Dar ◽

Mir Ahmad ◽

Shabir Mir ◽

Aijaz Malyar ◽

Varun Dogra ◽

...

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Kashmir Valley ◽

Biliary Ascariasis

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Prevelance ofHepatitis B, Hepatitis C and HIV Infections among People Who Inject Drugs- A Study from Tertiary Care Centre of Kashmir Valley, India

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2021/49191.15016 ◽

2021 ◽

Author(s):

Sanam Rasool Wani ◽

Anjum Farhana ◽

Danish Zahoor Pandith ◽

Mohammad Maqbool Dar

Keyword(s):

Hepatitis C ◽

People Who Inject Drugs ◽

Tertiary Care Hospital ◽

Demographic Data ◽

Tertiary Care ◽

Hiv Infections ◽

Enzyme Linked Immunosorbent Assay ◽

Care Hospital ◽

Kashmir Valley ◽

Hiv 1

Introduction: Drug addiction one of the greatest challenges face across the glob. The parenterally transmitted viruses like Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) occur more frequently in this high-risk group of population as compared with the general population. Aim: To find the prevalence of HBV, HCV and HIV in People Who Inject Drugs (PWIDs) attending a tertiary care hospital in Kashmir valley, India. Materials and Methods: A prospective descriptional study was conducted from October 2017 to October 2020 in the Department of Microbiology of a tertiary care hospital in Kashmir. Subjects included 200 (PWIDs) who voluntarily presented themselves at the drug clinic. Participants were tested for HBV, HCV and HIV infections. For HBV, surface antigen was detected using Enzyme-linked Immunosorbent Assay (ELISA), HCV was detected by HCV antibody test using ELISA and HIV was detected using combination of three rapid kits, COMBAIDS-RS ADVANTAGE ST, MERISCREEN HIV 1-2 WB and TREDRO HIV 1-2 Ab. Demographic data was collected from all the PWIDs. Results: Among 200 PWIDs,138 (69%) were in the age group of 16-25 years and none of them was more than 35 years of age. The mean age of PWIDs was 22.9 years. Out of 200, 20(10%) PWIDS had HCV antibodies, 7 (3.5%) were positive for HBV, and 1 (0.5%) had anti-HIV antibodies. A 73.5% of PWIDs belonged to urban Kashmir and majority of them (62.5%) were college going students. Conclusion: From present study, authors report a high prevalence of hepatitis C and B in PWIDs of Kashmir. It is also the fact that these figures are just the tip of the iceberg. Targeted intervention programs should make HBV/HCV testing, prevention and care more accessible for PWIDs.

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