scholarly journals Reference Ranges of Iron Profiles in Apparently Healthy Elderly in Sokoto, Nigeria

2021 ◽  
pp. 1-10
Author(s):  
Onuigwe, Festus Uchechukwu ◽  
Ibeh, Nancy Chitogu ◽  
Amilo, Grace Ifechukwudebelu
Keyword(s):  
Reference Values ◽  
Serum Iron ◽  
The Elderly ◽  
Serum Transferrin ◽  
Elderly Persons ◽  
Reference Ranges ◽  
Transferrin Receptors ◽  
Healthy Elderly ◽  
Local Reference ◽  
Apparently Healthy

Background: Iron is an important micronutrient in the body, lead to anaemia, frailty and cognitive disorders in the elderly when deficient. Aim: This study was aimed to determine reference values of iron profile in apparently healthy elderly persons in Sokoto and compared with the local reference values. Study Design: This was a comparative study Duration of Study: The study lasted for a period of one year between January to December, 2020. Methodology: This was a comparative study involving 105 apparently healthy elderly persons aged 60 years and above in Sokoto metropolis. Serum iron and total-iron binding capacity (TIBC) were determined using Iron Ferrozine method. Serum ferritin, Serum transferrin (Tf) and Serum Transferrin Receptors (sTfR) were assayed using enzyme-linked immunosorbent assay (ELISA). Transferrin Saturation (TS) and Serum Transferrin Receptors ferritin log (sTfR/FL) was calculated.  Data were expressed as percentiles, mean and standard deviation and analysed using t-test and one way ANOVA. Results: The study established reference ranges of Serum iron,TIBC, Serum ferritin, Tf, sTfR, TS and sTfR/FL was calculated.  in Sokoto. The study showed that iron and ferritin have high reference ranges than the local values in Sokoto. The local values for TIBC, ferritin, sTfR, TS and sTfR/FL were not available. Mean Ferritin (µg/L), sTfR (ng/L) and sTfR/Fl the test subjects were significantly higher in males than females in Sokoto (p=0.026), (p= 0.001), (p=0.044) and (p= 0.003) respectively. Iron, ferritin and TS increased as the BMI was increasing (p=<0.001). Conclusion: In conclusion, normal reference values obtained in this study notably vary with the local reference ranges used in the Sokoto metropolis. There is a need for each locality to have separate reference ranges for the elderly for their proper diagnosis and management of iron related disorders.

The Future Profile of Health Promotion and Disease Prevention in Japan

2005 ◽  
Vol 44 (02) ◽  
pp. 342-347 ◽  
Author(s):  
N. Doba ◽  
S. Hinohara
Keyword(s):  
Cohort Study ◽  
Population Analysis ◽  
Well Being ◽  
The Elderly ◽  
Health Evaluation ◽  
Social Emotional ◽  
Study Program ◽  
Healthy Elderly ◽  
The Individual ◽  
Apparently Healthy

Summary Objectives: One of the serious challenges for Japanese healthcare is the aging population. Analysis of health evaluation data, especially of the elderly over 75 years, is considered very important. In view of this prolonged life expectancy in Japan, our government started the new campaign of Healthy Japan 21, of which details are described, and also we will demonstrate the general profile of our perspective cohort study program concerning the new elder citizens in Japan. Methods and Results: Our group has started a health evaluation program for those apparently healthy new elder citizens over the age of 75. A ten-year cohort study is in progress, which is designed to accumulate health check-up data annually. The study collects information on physical well being, as well as information on the individual’s lifestyle, and social, emotional and spiritual environment. Such health appraisal is of primary importance. Preliminary results will be demonstrated with their special implications in clinical and epidemiological significance. The degree of frailty of the individual was also carefully evaluated, so that we can learn about the QOL of the seniors in Japan. Conclusions: At the present stage, we can only report a part of our study including the mental and spiritual environments of the individual. This kind of outcome study will give us some insights concerning the natural progress of frailty in the apparently healthy elderly.

Clinical Efficacy and Safety of Brahma Rasayana in Apparently Healthy Elderly Persons: A Prospective Multicenter Open-label Study

2018 ◽  
Vol 2 (4) ◽  
pp. 217-224
Author(s):  
Pradeep Dua ◽  
Rakesh Rana ◽  
Richa Singhal ◽  
Bhagwan Sahai Sharma ◽  
G Venkateswarlu ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Elderly Persons ◽  
Efficacy And Safety ◽  
Open Label ◽  
Open Label Study ◽  
Label Study ◽  
Healthy Elderly ◽  
Apparently Healthy

A Comparison of the Effects of Different Water Exercise Programs on Balance Ability in Elderly People

2008 ◽  
Vol 16 (4) ◽  
pp. 381-392 ◽  
Author(s):  
Koichi Kaneda ◽  
Daisuke Sato ◽  
Hitoshi Wakabayashi ◽  
Atsuko Hanai ◽  
Takeo Nomura
Keyword(s):  
Deep Water ◽  
Postural Sway ◽  
The Elderly ◽  
Elderly Persons ◽  
Exercise Programs ◽  
Water Exercise ◽  
Healthy Elderly ◽  
Balance Ability ◽  
Normal Water ◽  
Deep Water Running

This study compared the effects of 2 types of water exercise programs on balance ability in the elderly. Thirty healthy elderly persons (60.7 ± 4.1 yr) were randomly assigned to a deep-water-running exercise (DWRE,n= 15) group or a normal water exercise (NWE,n= 15) group. The participants completed a twice-weekly water exercise intervention for 12 wk. Exercise sessions comprised a 10-min warm-up on land, 20 min of water-walking exercise, 30 min of water exercise while separated into NWE and DWRE, a 10-min rest on land, and 10 min of recreation and relaxation in water. Postural-sway distance and tandem-walking time were decreased significantly in DWRE. Postural-sway area was decreased significantly in NWE. In both groups, simple reaction times were significantly decreased. The findings of this study show that a water exercise program including deep-water running is much better than normal water exercise for improving dynamic balance ability in the elderly.

scholarly journals Relationship of ventilatory inefficiency and low cardiorespiratory fitness in the elderly: a retrospective observational study

2019 ◽  
Vol 22 (4) ◽  
Author(s):  
Murillo Frazão ◽  
Luciana Margarida de Santana Madruga França ◽  
Samarony Caio Moreno Bezerra ◽  
Paulo Eugênio Silva
Keyword(s):  
Cardiorespiratory Fitness ◽  
Statistical Significance ◽  
Area Under The Curve ◽  
The Elderly ◽  
Cardiopulmonary Exercise Test ◽  
Control Group ◽  
Elderly Persons ◽  
Optimal Point ◽  
Healthy Elderly ◽  
Relationship Of

Abstract Objectives : To check if ventilatory inefficiency is related to low cardiorespiratory fitness in the elderly and to identify the variable(s) of the cardiopulmonary exercise test (CPET) best suited to determining this relationship. Methods : A retrospective analysis of 1357 CPETs was performed. Sixty-one subjects over 60 years old with a ventilatory efficiency slope (VE/VCO2) index >35 were selected and divided into two groups: low cardiorespiratory fitness (VO2<80% predicted) (n=22) and normal cardiorespiratory fitness (VO2>80% predicted) (n=39) and were compared with a control group of healthy elderly persons with normal cardiorespiratory fitness and VE/VCO2 slope index <35 (n=16), matched by gender, weight, height, and age. Results : Oxygen consumption had a low correlation with VE/VCO2 slope (r= -0.35, p<0.01), a moderate correlation with the cardiorespiratory optimal point (COP) (r= -0.59, p<0.001) and a strong correlation with oxygen uptake efficiency Slope (OUES) =0.92, p<0.0001). In relation to the ROC curve, the VE/VCO2 slope presented an area under the curve of 0.65, but without statistical significance (p> 0.05); the COP showed an area under the curve of 0.84 (p <0.0001) and the OUES presented an area under the curve of 0.81 (p<0.0001). Conclusion : Ventilatory inefficiency is related to poor cardiorespiratory fitness in the elderly. The COP and OUES were more accurate at predicting low cardiorespiratory fitness.

scholarly journals Immune response during disease and recovery in the elderly

1999 ◽  
Vol 58 (1) ◽  
pp. 85-98 ◽  
Author(s):  
Bruno Lesourd
Keyword(s):  
Immune Responses ◽  
Elderly Patients ◽  
Acute Phase ◽  
Protein Energy Malnutrition ◽  
The Elderly ◽  
T Helper ◽  
Aged Patients ◽  
Healthy Elderly ◽  
Protein Energy ◽  
Apparently Healthy

The present article reviews immune ageing and its relationship with nutritional ageing, with a particular insight into the influences of disease on both ageing processes. Immune ageing can be described primarily as the progressive appearance of immune dysregulations, mainly acquired immunity (mature: immature, naive: memory T lymphocyte subset decreases) leading to gradual increases in T-helper 2: T-helper 1 cells. This change is due initially to decreased thymic function, and later to accumulative antigen pressure over the lifespan. In contrast, innate immunity (macrophage functions) is preserved during the ageing process and in the elderly this leads to macrophage–lymphocyte dysequilibrium, which is particularly critical during on-going disease. Indeed, any disease induces long-lasting acute-phase reactions in aged patients and leads to body nutritional reserve (mainly protein) losses. Episodes of disease in the aged patient progressively deplete body nutritional reserves and lead to protein–energy malnutrition, undernutrition-associated immunodeficiency, and finally cachexia. Undernutrition is a common symptom in the elderly; protein-energy malnutrition is found in more than 50 % of hospitalized elderly patients and in most elderly diseased subjects. In addition, micronutrient deficit or low levels are common in home-living self-sufficient apparently-healthy elderly subjects. All these nutritional deficits induce decreased immune responses, and micronutrient deficits are now thought to be partly responsible for the decreased immune responses (immune ageing?) observed in the apparently-healthy elderly. Indeed, several studies have shown that micronutrient supplements induce increased immune responses in the healthy elderly. The progression of infectious diseases depends on immune responses and on nutritional status before the onset of illness in aged subjects. In addition, recovery depends on the intensity of acute-phase responses in the undernourished elderly. In fact, chronic acute-phase responses, commonly associated with diseases in aged patients, lead to progressive lowering of metabolic responses in the undernourished elderly. This can be quantified by increased production of free radicals during treatment and these increases may explain the difficulty in successfully treating aged patients. Nutritive therapy in order to improve metabolic processes and also to maintain body reserves should be considered as a necessary adjuvant therapy in the treatment of elderly patients.

Nutritional supplements in the Ambulatory Elderly Population: Patterns of Use and Requirements

DICP ◽  
1989 ◽  
Vol 23 (6) ◽  
pp. 490-495 ◽  
Keyword(s):  
Age Groups ◽  
National Research Council ◽  
Nutritional Supplements ◽  
The Elderly ◽  
World Health ◽  
Nutritional Deficiencies ◽  
Elderly Persons ◽  
National Academy Of Sciences ◽  
Supplement Use ◽  
Healthy Elderly

Older persons are thought to be the most frequent consumers of vitamin and mineral supplements. In this review, the use of nutritional supplements by the elderly was found to be common but was not greatly different from other age groups. Elderly persons living in Dunedin, Florida, reported nutritional supplement use less frequently than a random sample of registered nurses. Neither the Food and Nutrition Board of the National Academy of Sciences/National Research Council nor the World Health Organization has recognized the need for increasing the vitamin and mineral allowances for healthy elderly adults above those recommended for healthy young adults. It is important to recognize, however, that the elderly are at greater risk of developing nutritional deficiencies as a result of acute and chronic diseases, drug use, and social isolation, and they require careful monitoring.

Some EEG Findings in Old Age and Their Relationship to Affective Disorder

1956 ◽  
Vol 102 (429) ◽  
pp. 812-818 ◽  
Author(s):  
R. Maggs ◽  
E. C. Turton
Keyword(s):  
Affective Disorder ◽  
Old Age ◽  
Elderly Persons ◽  
Control Series ◽  
Clear Cut ◽  
Healthy Elderly ◽  
Apparently Healthy

The significance of the electro-encephalographic variations found in old age is not well defined and hence the value of this form of investigation as a prognostic measure is doubtful. Apart from a few papers such as Mengoli (1952), Mundy-Castle et al. (1954) and Obrist (1954), most of the published work contains no reference to findings obtained from a control series of persons of similar age and not suffering from a definite disability. This absence of definite criteria in respect of the EEG findings in records taken from apparently healthy elderly persons is important both as regards clear-cut abnormalities and also in reference to minor variations of doubtful significance.

Clinical Safety of Selected Ayurvedic Formulations as Rasayana in Apparently Healthy Elderly Persons: A Pharmacoepidemiological Perspective

2018 ◽  
Vol 2 (2) ◽  
pp. 122-131
Author(s):  
Manohar S Gundeti ◽  
Pitta Srinivas ◽  
Sneha Marlewar ◽  
Kishore Kumar ◽  
Rohit Ravte ◽  
...  
Keyword(s):  
Elderly Persons ◽  
Clinical Safety ◽  
Healthy Elderly ◽  
Apparently Healthy

scholarly journals A RANDOMISED DOUBLE-BLIND CLINICAL STUDY TO EVALUATE AND COMPARE THE EFFECTS OF VRIDDADARU RASAYANA WITH BHARGAVAPROKTA RASAYANA ON AGEING IN APPARENTLY HEALTHY ELDERLY SUBJECTS

2020 ◽  
pp. 13-23
Author(s):  
Manasa H P ◽  
Yogeesha Acharya ◽  
Sandesh Kumar
Keyword(s):  
Quality Of Life ◽  
Clinical Study ◽  
The Elderly ◽  
Elderly Subjects ◽  
Double Blind ◽  
General Body ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects ◽  
Apparently Healthy

According to estimation, India currently has 6.7% over 65 years of age, which is expected to increase to 20% by the year 2050. As growing old is a part of the life cycle, the effect of time is bound to happen and is unavoidable. The Kalajajara is a Swabhavika vyadhi, wherein, it is clearly mentioned that Swabhava balapravritta vyadhis being Yapya, can be managed through Bhojana, Paana, and Rasayana. Vriddadaru Rasayana is one such Rasayana mentioned in Gadanigraha especially for the elderly to promote healthy ageing and helping to prevent old age problems. Aims and objectives: To assess the effect of Vriddadaru Rasayana in improving the general body health and quality of life in the apparently healthy elderly subjects. Methodology– A Randomized double blind clinical study where 20 healthy elderly subjects were administered with Vriddadaru Rasayana for a period of 12 weeks. Observations and Results- Vriddadaru rasayana showed improvement in Ayurvedic parameters like Twakparushata, Slataasti, Slata sandhi, Utasahahani and Parakramahani but when compared with regard to objective parameters Vriddadaru rasayana showed significant values in DHEAS levels and 6MWT. Conclusion: Vriddadaru does Vatashamana, balancing the Doshas, increasing the Utsaha and Parakrama and helps in improving the Agni thus helping in Dhatuposhana in the elderly.

Walking with Visual Restrictions in Healthy Elderly and Young Adults

2002 ◽  
Vol 21 (2) ◽  
pp. 295-301 ◽  
Author(s):  
Sean Gallagher ◽  
Yves Lajoie ◽  
Michel Guay
Keyword(s):  
Young Adults ◽  
Visual Information ◽  
Older Persons ◽  
Visual Cues ◽  
Elderly Population ◽  
The Elderly ◽  
Elderly Subjects ◽  
Elderly Persons ◽  
Experimental Conditions ◽  
Healthy Elderly

ABSTRACTVisual requirements for a simple walking task were evaluated for young and elderly persons to determine if, with normal aging, elderly subjects require more visual information. Ten young adults and 10 elderly people were asked to complete a simple walking task within predetermined pathway boundaries under two conditions of visual restriction. In the reactive condition, subjects automatically received a 200 ms flash of visual information at the halfway point of the walkway. For the predictive condition, subjects did not receive any visual information during the walking trial, but were equipped with an emergency button that would provide 200 ms of visual information whenever they needed it. For both experimental conditions, subjects received additional flashes of visual information if they stepped out of the walkway boundaries. Results showed that older persons stepped out of bounds more often in the reactive condition and gave themselves more visual cues than the younger subjects in the predictive condition. The relative importance of vision during locomotion seems to be higher in the elderly population when compared to young adults.

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