scholarly journals The Effect of Different Exercise Intensities on Plasma Endostatin in Healthy Volunteers

2021 ◽  
pp. 30-38
Author(s):  
Inayat Shah ◽  
Tasleem Arif ◽  
Ron H. Baxendale ◽  
Muhammad Iftikhar ◽  
Alamgir Khan
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Physical Activities ◽  
Vigorous Exercise ◽  
P Values ◽  
Post Exercise ◽  
Low Intensity ◽  
Weekly Session ◽  
Potential Benefits ◽  
Low Intensity Exercise

Background: Physical activity decreases the risk and development of many angiogenesis related health problems including atherosclerosis. Physiological influence of different physical activities on plasma endostatin concentration is contradictory. This study aimed to determine the effects of mild, moderate and vigorous exercise on the concentration of endostatin. Methodology: 22 participants, 16 males (age = 30.6 ± 7.8 years) and 6 females (age = 26.5 ± 5 years) were recruited. Weekly session of different intensities exercise based on predicted maximum heart (60% (low), 70% (moderate) and 80% (vigorous)] were carried out. One pre and two post exercise samples were taken at 10 and 60 minutes. Results: Low intensity exercise insignificantly decreased the endostatin concentration at 10 and 60 minutes (P = 0.5 and 0.8). However, moderate (P values = 0.022. 0.004) and vigorous intensities (P= < 0.001, 0.02) increased the endostatin concentrations significantly at both intervals respectively. The effects were not significantly influenced by gender, exercise mode (walking vs running), components of exercise (HR, Speed, Gradients, distance, duration) or metabolism during exercise (VO2 max, VCO2, RER, Energy expenditure). Conclusion: Low intensity exercises did not influence endostatin concentration. However, moderate to high intensity exercises significantly increase endostatin concentration and may have potential benefits.

Energy Expenditure in Obese vs Lean Children at High vs Low Intensity Exercise

2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 56-57
Author(s):  
Holly M. Ippisch ◽  
Wayne A. Mays ◽  
Michelle A. Wolfe ◽  
Sandra K. Knecht ◽  
Yvette M. Gerdes ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Low Intensity ◽  
Lean Children ◽  
Low Intensity Exercise

1. The Effects of an Aerobic Exercise Intervention on Daily Activity Patterns

2016 ◽  
Author(s):  
James Bouma
Keyword(s):  
Physical Activity ◽  
Aerobic Exercise ◽  
Daily Activity ◽  
Exercise Intervention ◽  
Vigorous Physical Activity ◽  
Activity Patterns ◽  
Low Intensity ◽  
Low Volume ◽  
Low Intensity Exercise ◽  
Daily Activity Patterns

The purpose of this study was to examine the effects of participation in an aerobic exercise intervention on daily activity occurring outside of the structured exercise sessions. Participants were randomized into one of the following 4 conditions: 1) No-exercise, 2) Low volume, low intensity exercise (LVLI), 3) High volume, low intensity exercise (HVLI), 4) Low volume, high intensity (LVHI). Physical activity was measured over 7 days with an accelerometer at baseline and during week 8 of the intervention. Activity was defined as: sedentary behaviour (SED; < 100 counts/minute), light physical activity (LPA; 100 to 1951 counts/minute), moderate-to-vigorous physical activity (MVPA; ≥1952 counts/minute), and total physical activity (TPA; LPA + MVPA). Activity was quantified as average total minutes per day of each SED, LPA, MVPA, and TPA. A one-way ANOVA was used to determine if time spent in SED, LPA, MVPA, and TPA changed from baseline to week 8. Seventy-one participants (No-exercise; n=12, LVLI n=17, HVLI n=24, LVHI; n=18,) with a mean age of 54 y and waist circumference of 110 cm completed 8 weeks of the intervention. There were no significant differences in SED, LPA, MVPA, or TPA between groups at baseline. There was no significant change in SED, LPA, MVPA, or TPA at week 8 compared to baseline (p>0.05). Similarly, there were no significant differences in activity variables between exercise conditions. Our observations suggest that daily activity patterns do not change with the implementation of an exercise intervention in men and women.

scholarly journals Defining the contribution of skeletal muscle pyruvate dehydrogenase α1 to exercise performance and insulin action

2018 ◽  
Vol 315 (5) ◽  
pp. E1034-E1045 ◽  
Author(s):  
Kristoffer Svensson ◽  
Jessica R. Dent ◽  
Shahriar Tahvilian ◽  
Vitor F. Martins ◽  
Abha Sathe ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Insulin Sensitivity ◽  
Energy Expenditure ◽  
Exercise Performance ◽  
Pyruvate Dehydrogenase ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Low Intensity ◽  
Low Intensity Exercise ◽  
Muscle Contractile

The pyruvate dehydrogenase complex (PDC) converts pyruvate to acetyl-CoA and is an important control point for carbohydrate (CHO) oxidation. However, the importance of the PDC and CHO oxidation to muscle metabolism and exercise performance, particularly during prolonged or high-intensity exercise, has not been fully defined especially in mature skeletal muscle. To this end, we determined whether skeletal muscle-specific loss of pyruvate dehydrogenase alpha 1 ( Pdha1), which is a critical subunit of the PDC, impacts resting energy metabolism, exercise performance, or metabolic adaptation to high-fat diet (HFD) feeding. For this, we generated a tamoxifen (TMX)-inducible Pdha1 knockout (PDHmKO) mouse, in which PDC activity is temporally and specifically ablated in adult skeletal muscle. We assessed energy expenditure, ex vivo muscle contractile performance, and endurance exercise capacity in PDHmKO mice and wild-type (WT) littermates. Additionally, we studied glucose homeostasis and insulin sensitivity in muscle after 12 wk of HFD feeding. TMX administration largely ablated PDHα in skeletal muscle of adult PDHmKO mice but did not impact energy expenditure, muscle contractile function, or low-intensity exercise performance. Additionally, there were no differences in muscle insulin sensitivity or body composition in PDHmKO mice fed a control or HFD, as compared with WT mice. However, exercise capacity during high-intensity exercise was severely impaired in PDHmKO mice, in parallel with a large increase in plasma lactate concentration. In conclusion, although skeletal muscle PDC is not a major contributor to resting energy expenditure or long-duration, low-intensity exercise performance, it is necessary for optimal performance during high-intensity exercise.

Habitual and Low-Intensity Physical Activity in People with Multiple Sclerosis

2016 ◽  
Vol 17 (1) ◽  
pp. 77-86 ◽  
Author(s):  
Hannah L. Gullo ◽  
Anna L. Hatton ◽  
Sally Bennett ◽  
Jennifer Fleming ◽  
David H. K. Shum
Keyword(s):  
Physical Activity ◽  
Multiple Sclerosis ◽  
Health Status ◽  
Activity Level ◽  
Low Intensity ◽  
Habitual Activity ◽  
Intensity Physical Activity ◽  
Insufficient Physical Activity ◽  
Potential Benefits ◽  
The Impact

People with Multiple Sclerosis (MS) undertake insufficient physical activity based on current guidelines. Recent work points to the benefits of increasing the amount of time spent in all non-sedentary physical activity. The current study sought to explore the potential benefits to community participation, as well as examine factors predictive, of engagement in ‘habitual’ and/or low-intensity physical activity. Seventy-four people with MS were compared to 67 healthy controls using the Frenchay Activities Index (FAI). Findings revealed differences in habitual activity level (p < .001), and low-intensity physical activity (p < .001), with people with MS having a lower level of engagement than healthy people. After controlling for the impact of MS on mobility, years since symptom onset, physical fatigue and reduced positive affect were the most significant predictors of engagement in ‘at least weekly’ low-intensity physical activity. Higher frequency of low-intensity physical activity was significantly associated with greater home, social and occupational participation (all p < .05), and physical health status (p < .01), but not mental health status (p = .964) in people with MS. Results suggest that improving habitual activity level and engagement in low-intensity physical activity may be of benefit for people with MS.

scholarly journals The Energy Expenditure of Free-Living Physical Activities in Primary Schoolchildren

2016 ◽  
Vol 13 (s1) ◽  
pp. S57-S61 ◽  
Author(s):  
Alison L. Innerd ◽  
Liane B. Azevedo
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Metabolic Rate ◽  
Indirect Calorimetry ◽  
Resting Metabolic Rate ◽  
Physical Activities ◽  
Free Living ◽  
Metabolic Equivalent ◽  
Primary Schoolchildren ◽  
Vigorous Intensity

Background:The aim of this study is to establish the energy expenditure (EE) of a range of child-relevant activities and to compare different methods of estimating activity MET.Methods:27 children (17 boys) aged 9 to 11 years participated. Participants were randomly assigned to 1 of 2 routines of 6 activities ranging from sedentary to vigorous intensity. Indirect calorimetry was used to estimate resting and physical activity EE. Activity metabolic equivalent (MET) was determined using individual resting metabolic rate (RMR), the Harrell-MET and the Schofield equation.Results:Activity EE ranges from 123.7± 35.7 J/min/Kg (playing cards) to 823.1 ± 177.8 J/min/kg (basketball). Individual RMR, the Harrell-MET and the Schofield equation MET prediction were relatively similar at light and moderate but not at vigorous intensity. Schofield equation provided a better comparison with the Compendium of Energy Expenditure for Youth.Conclusion:This information might be advantageous to support the development of a new Compendium of Energy Expenditure for Youth.

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