scholarly journals A Case Report of ChAdOx1 nCoV- 19 Corona Virus Recombinant Vaccine Related Granuloma Annulare

Author(s):  
S. Swetha Shri ◽  
Jayakar Thomas

Background: Granuloma annulare (GA) is a benign, self-limiting inflammatory skin condition of unknown origin that may occur following multiple etiological triggers. GA incited secondary to vaccinations has been rarely reported in the medical literature. The COVID-19 pandemic has introduced extensive global immunization against the SARS-COV-2 virus, bringing a gamut of vaccine-related complications. We elucidate a case report of the spontaneous eventuality of GA following ChAdOx1 nCoV-19 Corona Virus Recombinant Vaccine. Case Report: A healthy 26-year male presented with a one-week history of asymptomatic single, flesh-pink patch with a raised margin over his left ventral forearm. On close examination, the margin of the lesion had multiple annularly arranged papules. Biopsy of lesion was done, and histopathology revealed numerous palisading granulomas in the dermis consistent with findings of localized GA. The patient was managed with once-daily external application high potent topical corticosteroids, which was used intermittently by the patient. However, the lesion showed spontaneous resolution in one month. Conclusion: Identifying ChAdOx1 nCoV- 19 Vaccine-related adverse events following its first dose is paramount, as evidence of the proportion of local or systemic severe cutaneous adverse skin reaction (SCAR) on subsequent dosing is a paucity. A more extensive systematic review corroborating SCARs and safety profile following immunization with ChAdOx1 nCoV-19 Vaccine prevails to be the need of the hour.

2015 ◽  
Vol 7 (4) ◽  
pp. 163-171
Author(s):  
Slobodan Stojanović ◽  
Marina Jovanović ◽  
Nada Vučković

Abstract Lichen striatus (linear lichenoid dermatosis) is an uncommon, self-limited, inflammatory, linear skin condition of unknown origin. The causes of linear distribution are unknown, though the pattern of lichen striatus (LS) mostly follows the lines of Blaschko (BL). The condition most commonly occurs in children between 5 and 15 years of age, usually after the first year of life. We report a 27-year-old, otherwise healthy flight attendant with LS whose diagnosis was based on: the history of sudden appearance and rapid linear spread of lesions; clinical presentation of small pink, coalescing scaly papules without umbilication or Wickham’s striae, linear distribution following one BL down a lower limb to the ankle, with a band broadening into plaque on the left buttock; histology showed some hyperkeratosis, lichenoid dermatitis similar to lichen planus, but with the presence of inflammatory infiltrate in the papillary dermis and also deeper in the perifollicular region. The inflammatory infiltrate consisted mainly of limphocytes, with some melanophages and histiocytes. There is no standard treatment for LS, and it is given for cosmetic or psychological reasons only, as we have done in our patient due to slight pruritus and occupational reasons. With regard to her occupational demands, in order to achieve satisfying results, she was successfully treated with cryotherapy, which she tolerated well, without any side effects. Cryotherapy was performed twice, with a two-week interval. Full resolution was achieved twelve weeks after cryotherapy. In conclusion, we present an adult female who developed lichen striatus suddenly three months after delivery and was successfully treated with cryotherapy.


2015 ◽  
Vol 4 ◽  
pp. 322-325
Author(s):  
Joanna Bacharewicz-Szczerbicka ◽  
Teresa Reduta ◽  
Paulina Kiluk ◽  
Anna Andrzejewska ◽  
Iwona Flisiak

2021 ◽  
Vol SP (1) ◽  
Author(s):  
Poonam Dhankher ◽  
Sakshi ◽  
Dimple Choudhry

Verucae or plantar warts is a painful skin condition that demonstrates a high resistance to various treatments. They can be caused by trauma or human papilloma virus. The infection is mostly caused by a breach in the skin. The virus is usually contacted by walking barefoot in community swimming pool areas. The condition is common in sports persons. Our research focused on warts that occur on plantar surface of foot also known as plantar warts. They result in pain with pressure on weight bearing surfaces so walking is difficult and painful. Risk factors include using community showers barefoot, previous history of warts and decreased immune function. Case Report: We present a case report of a female aged 24 years who was clinically diagnosed with plantar wart. She developed recurrent plantar warts. For a year she was treated with pairing and punch excision with no success. Then ultrasound program was initiated with dosage of 0.6 watt /cm2 and increased up to 1 watt/cm2 for 15 min given at 1-week interval for 15 weeks. At the end of 15th week, the plantar wart had completely disappeared.


2020 ◽  
Vol 42 (2) ◽  
pp. 250-253
Author(s):  
Carolt Arana Aliaga ◽  
Leonor Fayos de Arizon ◽  
Rosario Montañés Bermúdez ◽  
Jose A. Ballarín Castán ◽  
Anna Vila Santandreu

ABSTRACT This study reports a case of a 13-year-old male with a 3-year history of severe and intermittent hypokalemia episodes of unknown origin, requiring admission to the intensive care unit (ICU) for long QT syndrome (LQTS), finally diagnosed of redistributive hypokalemia secondary to the abuse of β-adrenergic agonists in the context of a probable factitious disorder.


2015 ◽  
Vol 21 (2) ◽  
pp. 95-100
Author(s):  
Cristina-Mădălina Deacu ◽  
Adriana Iordan ◽  
R. Baz

Abstract A variety of diffuse diseases affect the calvaria. They may be identified clinically as palpable masses or incidentally in radiologic examinations. The purpose of this study is to illustrate the main diffuse calvarial lesions starting from a case report of fibrous dysplasia of the cranial vault. A 68-year-old male patient who presented with a history of right otalgia and bloody otorrhea was diagnosed to have fibrous dysplasia based on the radiological features. Most diffuse diseases of the calvaria are benign non-neoplastic lesions of unknown origin. The radiologist has a long list of differential diagnosis and their true etiology may be puzzling when the medical evaluation is based only on imaging findings.


2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Mohd Shaiful Ehsan Shalihin ◽  
Mohd Aizuddin Abd Rahman

Introduction: Psoriasis is a chronic, noncontagious, multifactorial inflammatory skin condition that has several subtypes. Therefore, prior to actual diagnosis, it may mimics other similar illnesses. In acute condition, it typically presents with erythroderma macules associated with pain and itchiness rather than  hypopigmented and numbness lesions that supposedly occurs in post-treatment or post-acute phase, rather than as initial presentation. Case report: We report a case of 18-year-old girl, who presented with nonspecific localized hypopigmented rash over her forehead and scalp associated with numbness for three weeks duration. She had no itchiness or rashes elsewhere. She had no history of atopy or recent exposure to new cosmetics. She had no joint pain or hair loss. She had no recent contact with anyone with similar lesion. No significant similar history among family members. Clinically, there is reduced in both soft touch and pin-prick sensation over affected areas. We refer this case to dermatologist with possibility of leprosy in view of her reduced sensation over the lesion. To our surprise, the skin biopsy revealed supportive points towards psoriasis. She responds well towards coal tar and topical corticosteroids-the first line treatment of psoriasis. Her numbness has also resolved. This case highlights that psoriasis do presents with localized numbness in which its diagnosis should be take into consideration before confining the disease towards leprosy only.


2018 ◽  
Vol 12 (3) ◽  
pp. 32-35
Author(s):  
Justyna Havemeister ◽  
Karolina Chilicka

Background: The history of microdermabrasion dates back to ancient Egypt. The first treatment in Europe occurred in 1985 and has since become a popular method of exfoliation of the superficial layers of skin. Microdermabrasion is an effective method of taking care of the skin of the face and body, bringing about immediate effects in the treatment of deep scars and stretch marks. Aim of the study: To determine the effectiveness of diamond microdermabrasion on a person with hyperuricemia of the sebaceous glands. Materials and methods: Based on interviews, a case analysis, and the impact of diamond microdermabrasion on the structure of the skin’s surface, the level of hydration, oiliness and epidermal exfoliation were analyzed. Case report: The subject was a 22-year-old woman struggling with oily skin. A few acne lesions and a large number of blackheads were observed in her nasal area. An interview was conducted prior to the procedure to eliminate any contraindications. The study was conducted within a period of 4 months at 3-week intervals. The Nati Skin Analyzer was used to determine the skin parameters of the patient. Results: After applying a series of treatments using the microdermabrasion apparatus, satisfactory results were obtained in the form of reduced peeled sebum and improved skin hydration in the T and U zones. Conclusions: The study shows that diamond microdermabrasion treatment has a beneficial effect on the patient’s skin condition. Phot ographs before and after the surgery document the positive effects this series of treatments had. There was a decrease in the level of sebum secretion and the elimination of skin changes in the form of acne or open comedones.


F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 107
Author(s):  
Marie Angelique Lazo-Betetta ◽  
Renzo Perez-Vasquez ◽  
Arantxa Sanchez-Boluarte ◽  
Fiorella Inga-Berrospi ◽  
J. Antonio Grandez-Urbina

Morphea is an inflammatory, sclerosing skin condition of unknown cause that generally does not present systemic manifestations. A 66-year-old Caucasian Peruvian female patient, who was previously a nurse, presented with a prior history of 4 years of indurated dermal plaque lesions with constant progression. Diagnosis of morphea was made by clinical examination and skin biopsy. The patient started topical treatment with methoxsalen and phototherapy. When no improvement was seen, it was switched to methotrexate. However, due to changes in liver profile, phototherapy was restarted with progressive clinical improvement. It is essential to differentiate all morphea subtypes for proper management.


Sign in / Sign up

Export Citation Format

Share Document