scholarly journals Successful one-stage operation for ipsilateral, synchronous carcinomas of the breast and lung: A case report

2017 ◽  
Author(s):  
Liwei Meng ◽  
Liming Huang ◽  
Yingchun Xu
Keyword(s):  
Lung Cancer ◽  
Breast Conserving Surgery ◽  
Left Breast ◽  
Chest Ct ◽  
Primary Carcinoma ◽  
The Body ◽  
Ipsilateral Breast ◽  
One Stage ◽  
Node Biopsy ◽  
The Right

Abstract The incidence of double primary malignancies is very low, particularly, a case of synchronous carcinomas of the ipsilateral breast and lung. Determining whether to have a one-stage operation for ipsilateral breast cancer and lung cancer is a challenge for the surgeon. The current study presents a case of a 56-year-old female, with a rigid textured mass measuring approximately 18×20 mm above the areola of the right breast and chest CT showing a mass of 20 × 14 mm at the tip segment of right upper lobe of the lung. A diagnosis of a synchronous dual primary carcinoma of the right lung (cT1N0M0) and right breast (cT1N0M0) was made. The patient underwent a right breast-conserving surgery, sentinel node biopsy, and right upper lobectomy and lymphadenectomy with a video-assisted thoracoscopic technique simultaneously. To our knowledge, in the previous literature, there was no one-stage operation for ipsilateral, synchronous carcinomas of the breast and lung and only one reported case with left breast and right lung cancer underwent a one-stage operation. This report first presents the successful treatment of a case with synchronous primary breast and lung carcinomas on the same side of the body with a one-stage operation and therefore is educational.

scholarly journals Primary lung cancer with metastasis to the ipsilateral breast-a case report

2017 ◽  
Vol 6 (1) ◽  
pp. 334 ◽  
Author(s):  
Abdalla Saad Abdalla Al-Zawi ◽  
Andrzej Ratajczak ◽  
Philip Idaewor ◽  
Mohamed Elamass ◽  
Anita Lazarevska ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Malignant Melanoma ◽  
Rare Case ◽  
Primary Lung Cancer ◽  
Left Breast ◽  
Contralateral Breast ◽  
Ipsilateral Breast ◽  
Breast Lump ◽  
Breast Metastases

The metastasis of extra-mammary malignancy to breast is extremely rare; literature reports the incidence between 0.4-1.3%. Primary sites include the contralateral breast, leukaemia, lymphoma, malignant melanoma, sarcoma, lung, prostate, ovary, colon and the stomach. Here we present a rare case in which lung cancer was found to metastasise to the breast. Initially the patient presented with chest symptoms and a left breast lump was detected clinically. The radiological and histological investigations confirmed the diagnosis of primary lung cancer with breast metastases. Prognosis of such cases is generally poor.

scholarly journals Pelvic Kidney Mimicking Skeletal Metastasis on Bone Scan- Interesting Image

2021 ◽  
Vol 22 (2) ◽  
pp. 155-156
Author(s):  
Mohammed Mehedi Al Zahid Bhuiyan ◽  
Azmal Kabir Sarker ◽  
Hongyoon Choi ◽  
Minseok Suh ◽  
Gi Jeong Cheon
Keyword(s):  
Bone Scan ◽  
Left Kidney ◽  
Renal Cysts ◽  
Skeletal Metastasis ◽  
Breast Conserving Surgery ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
Hepatic Cyst ◽  
Large Area ◽  
The Right

A 57-year-old female patient underwent left breast-conserving surgery with sentinel lymph node biopsy for Left breast carcinoma (stage IIA). The patient had hypertension and diabetes mellitus. Other findings include multiple hepatic cyst, bilateral renal cysts and uterine myoma. She had no significant renal symptoms and her liver &renal function test were normal.She was sent for Technetium-99m-methylene diphosphonate (99mTc-MDP) bone scan. There was a large area of intense tracer concentration in the region of right sacro-iliac (SI) joint which appeared like an osteoblastic metastasis at first glance. However, absence of uptake in the right renal fossa with the left kidney being normal in position contemplated the probability of right-sidedpelvickidneywhich was confirmed later by a contrast enhanced computerized tomography (CT) scan of abdomen that showed a pelvic right kidney overlying the sacrum. Bangladesh J. Nuclear Med. 22(2): 155-156, Jul 2019

scholarly journals Reactivation of TB during administration of durvalumab after chemoradiotherapy for non-small-cell lung cancer: a case report

Immunotherapy ◽  
2020 ◽  
Author(s):  
Yasuhiro Kato ◽  
Yasutaka Watanabe ◽  
Yuki Yamane ◽  
Hideaki Mizutani ◽  
Futoshi Kurimoto ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Checkpoint Inhibitors ◽  
Chest Ct ◽  
Small Cell ◽  
Small Cell Lung ◽  
Intermittent Fever ◽  
Unresectable Stage ◽  
The Right

Background: Tuberculosis (TB) is considered to be an adverse effect of treatment with immune checkpoint inhibitors. Methodology & results: Our case was a 75-year-old woman diagnosed with unresectable stage III non-small-cell lung cancer. After radical chemoradiotherapy was completed, durvalumab was initiated as a consolidation therapy. However, since chest CT showed appearances of infiltration shadows scattered in the periphery of the lungs after five doses of immunotherapy, duruvalumab was discontinued. 6 weeks later, the patient was aware of intermittent fever. Chest CT scan showed the appearance of a tree-in-bud pattern in the right lung. Acid-fast bacilli stain of sputum was positive and the PCR test was positive for Mycobacterium tuberculosis. Conclusion: Duruvalumab as PD-L1 blockade may activate TB.

scholarly journals Clinical and morphological case of lung cancer with generalized metastases to the internal organs

2021 ◽  
Vol 23 (3) ◽  
pp. 525-528
Author(s):  
Olga V. Vorobeva
Keyword(s):  
Lung Cancer ◽  
Lymph Nodes ◽  
Tumor Tissue ◽  
Clinical Manifestations ◽  
The Body ◽  
Hematogenous Metastasis ◽  
Internal Organs ◽  
Multiple Metastases ◽  
Leading Position ◽  
The Right

Lung cancer has occupied a leading position in the structure of cancer morbidity and mortality throughout the world for many years. Lifetime diagnosis is often difficult due to the absence of any defining signs of cancer, and it is quite difficult to track the first signs of lung cancer. This is justified by the fact that the lungs are completely devoid of nerve endings and the presence of 26% of healthy lung tissue is sufficient to provide the body with the required amount of oxygen. Prolonged absence of clinical manifestations leads to late seeking medical help, which is often fatal. Description of the case. A 65-year-old patient who died at home was referred for a postmortem examination. The sectional study revealed signs of peripheral cancer of the right lung with multiple metastases in all fields of the lungs, in the liver, spleen, pancreas, with no metastases in the lymph nodes. Histological examination revealed extensive areas of tumor tissue, consisting of solid structures with glandular differentiation of tumor tissue of various sizes and shapes, with round and oval atypical nuclei. There was a pronounced polymorphism of cells, with a large number of pathological mitoses. Thrombi were detected in the lumen of the segmental and small branches of the pulmonary artery. Thus, the presented case is of particular interest for practicing physicians due to the fact that with adenocarcinoma of the lung, there were no characteristic metastases to the lymph nodes. Hematogenous metastasis occurred with the development of generalized metastases to the internal organs.

scholarly journals Geometric and Dosimetric Changes in Tumor and Lung Tissue During Radiotherapy for Lung Cancer With Atelectasis

2021 ◽  
Vol 11 ◽  
Author(s):  
Hua Chen ◽  
Yan Shao ◽  
Xiaohua Gu ◽  
Zhijie Zheng ◽  
Hao Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lung Tissue ◽  
Tumor Volume ◽  
Center Of Mass ◽  
The Body ◽  
Complete Regression ◽  
Lung Cancer Patients ◽  
Ipsilateral Lung ◽  
Normal Tissues ◽  
The Right

Background and PurposeThis article retrospectively characterized the geometric and dosimetric changes in target and normal tissues during radiotherapy for lung cancer patients with atelectasis.Materials and MethodsA total of 270 cone beam computed tomography (CBCT) scans of 18 lung patients with atelectasis were collected. The degree and time of resolution or expansion of the atelectasis were recorded. The geometric, dosimetric, and biological changes in the target and lung tissue were also quantified.ResultsThere were two patients with expansion, four patients with complete regression, six patients with partial regression, and six patients with no change. The time of resolution or expansion varied. The tumor volume increased by 3.8% in the first seven fractions, then decreased from the 9th fraction, and by 33.4% at the last CBCT. In the LR direction, the average center of mass (COM), boundaries of the tumors gradually shifted mediastinally. In the AP direction, the COM of the tumors was shifted slightly in the posterior direction and then gradually shifted to the anterior direction; the boundaries of the tumors all moved mediastinally. In the SI direction, the COM of the tumors on the right side of the body was substantially shifted toward the head direction. The boundaries of the tumors varied greatly. D2, D98, Dmean, V95, V107, and TCP of the PTV were reduced during radiotherapy and were reduced to their lowest values during the last two fractions. The volume of the ipsilateral lung tended to increase gradually. The V5, V10, V20, V30, V40, and NTCP of the total lung gradually increased with the fraction.ConclusionsFor most patients, regression of the atelectasis occurred, and the volume of the ipsilateral lung tended to increase while the tumor volume decreased, and the COM and boundary of the tumors shifted toward mediastinum, which caused an insufficient dose to the target and an overdose to the lungs. Regression or expansion may occur for any fraction, and it is therefore recommended that CBCT be performed at least every other day.

scholarly journals Bilateral Primary Breast Cancer: A Case Report and Literature Review

2020 ◽  
Author(s):  
Shuyao Fan ◽  
Xidong Gu ◽  
Zhehao Liang ◽  
Yuping Mao ◽  
Changyu Zhou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Cancer ◽  
Left Lung ◽  
Distant Metastases ◽  
Breast Conserving Surgery ◽  
Left Breast ◽  
Cancer History ◽  
Diagnosis And Prognosis ◽  
Systemic Treatments ◽  
The Right

Abstract BackgroundInvasive micropapillary carcinoma (IMPC) and secretory carcinoma of the breast (SCB) are relatively rare types of breast cancer. IMPC is usually associated with high incidence of lymphovascular invasion, lymph node metastasis and poor prognosis. While SCB usually carries a relatively favorable prognosis, cases of axillary and distant metastases have been reported. Clinicians generally adopt systemic treatments based on the histopathological findings of the patients to improve the prognosis, but there is currently no consensus on the optimal treatment for these two types of cancer.Case presentationWe treated a 50‐year‐old woman with lung cancer history who presented with a single lump in each breast. Following bilateral breast-conserving surgery, the diagnosis of SCB of the left breast and IMPC of the right breast was confirmed with immunohistochemistry. It is worth noting that the pathological results of left lung adenocarcinoma centered on micropapillary-type was same as the invasive micropapillary component of right breast.ConclusionsWe reported this case of bilateral primary relatively-rare-form breast cancer for its extremely rare occurrence and there are less than 20 cases of SCB reported worldwide till now. It is also significative to distinguish this primary tumor of right breast from metastatic cancer. Our histopathologic diagnosis and synthetical therapy scheme will provide material for SCB and IMPC. To facilitate the diagnosis and prognosis of such relatively rare tumors, more cases will need to be reported.

scholarly journals Demographic and Clinical Profile of Tuberculous Mastitis Patients at Tebet General Hospital, Jakarta

2019 ◽  
Vol 3 (2) ◽  
pp. 32
Author(s):  
Desak Ketut Nari Swari Pramegia ◽  
Rio Putratama Achmad Faried ◽  
Kelvin Setiawan ◽  
Bramastha Aires Rosadi ◽  
Terry Renata Lawanto
Keyword(s):  
General Hospital ◽  
Left Breast ◽  
The Body ◽  
Clinical Profile ◽  
Hiv Test ◽  
Unilateral Involvement ◽  
The Mean ◽  
One Year ◽  
The Right ◽  
Possible Cause

Aim: Objective of the study is to find out the demographic and clinical profile of tuberculous mastitis (TM) patients. Methods: The study was carried out for a period of one year from August 2017 to August 2018 at Tebet General Hospital. Histopathologically diagnosed cases of TM were retrospectively studied. Results: All eight patients diagnosed as suffering from TM were females with the mean age of 37.25 years. Of these, two patients were lactating, six others were not, and 75% were multiparous. Unilateral involvement was observed in all cases. The right breast was affected in 62.5% and left breast in 37.5% cases. Patients presented with a solitary lump on one breast (87.5%), swelling of the breast (37.5%), and breast pain (100%). In the present study, two of the patients had previous positive tuberculosis (TB) contact and more than half found to be below an average economic level. All the patients were negative on the HIV test; also, there was no focus of TB elsewhere in the body. Conclusion: Tuberculosis should be considered as one possible cause of either mastitis or breast abscess. Histopathology examination played an important role in the diagnosis of TM. Standardized sequence for the diagnosis of TM is needed to increase awareness of the disease.

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