The Politics of Care

This chapter builds up the first case study of the book by examining the trajectory of diseased animals. It investigates how rinderpest or the Calcutta Epizootic of 1864 came to be constructed as a visible threat to the empire. Additionally, by focusing on major crosscurrents concerning cattle health, it demonstrates how a renewed protectionist stance manifested itself in the form of colonial legislations along with a surge of anti-animal cruelty literature among Bengalis. What sets this chapter apart from other works on animal disease in colonial India is that it demonstrates how attempts to control animal disease eventually merged with humanitarian initiatives. While the sentiment of compassion towards nonhuman animals was not a novelty in India, its contact with the Raj lent a different hue to it. Compassion was no longer a commitment to the virtue of “ahimsa” (non-injury to a living being)- but implied a loyalty to bigyan or “science.” The best example of the mingling of ahimsa and bigyan is the foundation of the Belgachia Veterinary infirmary in 1901.

Echinacea purpurea L. (Moench) Hemagglutinin Effect on Immune Response In Vivo

Echinacea purpurea L. (Moench) is used in traditional and conventional medicine. However, there is lack of data on the biological activities of primary plant metabolite lectins. The aim of our experiment was to find out how lectin LysM (lysine motif), which was previously purified, affects the immune response in vivo. Eight-week-old BALB/c male mice (n = 15) received four weekly 250 μg/kg peritonial injections of purified Echinacea purpurea L. (Moench) roots’ LysM lectin. The control animal group (n = 15) received 50 μL peritoneal injections of fresh Echinacea purpurea L. (Moench) root tincture, and the negative control animal group (n = 15) received 50 μL peritoneal injections of physiological solution. At the fifth experimental week, the animals were sedated with carbon dioxide, and later euthanized by cervical dislocation, and then their blood and spleen samples were collected. The leukocytes’ formula and lymphocytes’ count was estimated in blood samples, the T lymphocytes’ density was evaluated in spleen zones. A statistically significant (p < 0.05) difference between each group was observed in the leukocytes’ formula (monocytes’ percentage, also little, medium and giant size lymphocytes). The purple coneflower fresh roots’ tincture significantly decreased (p < 0.05) the T lymphocytes’ quantity in peritoneal lymphoid sheaths (PALS) compared with the physiological solution injection’s group (p < 0.05) and the lectin injection’s group (p < 0.001). Meanwhile, lectin injections caused a significant (p < 0.01) increase in the T lymphocytes in a spleen PALS zone, compared with the physiological solution and tincture injection’s group. Our data suggests that LysM lectin acts as an immunostimulant, while fresh purple coneflower tincture causes immunosuppression.

Altered functional interactions between neurons in primary visual cortex of macaque monkeys with experimental amblyopia

Amblyopia, a disorder in which vision through one of the eyes is degraded, arises because of defective processing of information by the visual system. Amblyopia often develops in humans after early misalignment of the eyes (strabismus) and can be simulated in macaque monkeys by artificially inducing strabismus. In such amblyopic animals, single-unit responses in primary visual cortex (V1) are appreciably reduced when evoked by the amblyopic eye compared with the other (fellow) eye. However, this degradation in single V1 neuron responsivity is not commensurate with the marked losses in visual sensitivity and resolution measured behaviorally. Here we explored the idea that changes in patterns of coordinated activity across populations of V1 neurons may contribute to degraded visual representations in amblyopia, potentially making it more difficult to read out evoked activity to support perceptual decisions. We studied the visually evoked activity of V1 neuronal populations in three macaques ( Macaca nemestrina) with strabismic amblyopia and in one control animal. Activity driven through the amblyopic eye was diminished, and these responses also showed more interneuronal correlation at all stimulus contrasts than responses driven through the fellow eye or responses in the control animal. A decoding analysis showed that responses driven through the amblyopic eye carried less visual information than other responses. Our results suggest that part of the reduced visual capacity of amblyopes may be due to changes in the patterns of functional interaction among neurons in V1. NEW & NOTEWORTHY Previous work on the neurophysiological basis of amblyopia has largely focused on relating behavioral deficits to changes in visual processing by single neurons in visual cortex. In this study, we recorded simultaneously from populations of primary visual cortical (V1) neurons in macaques with amblyopia. We found changes in the strength and pattern of shared response variability between neurons. These changes in neuronal interactions could impair the visual representations of V1 populations driven by the amblyopic eye.

Evaluation of an in vivo model for ventricular shunt infection: a pilot study using a novel antimicrobial-loaded polymer

OBJECTIVEVentricular shunt infection remains an issue leading to high patient morbidity and cost, warranting further investigation. The authors sought to create an animal model of shunt infection that could be used to evaluate possible catheter modifications and innovations.METHODSThree dogs underwent bilateral ventricular catheter implantation and inoculation with methicillin-sensitive Staphylococcus aureus (S. aureus). In 2 experimental animals, the catheters were modified with a polymer containing chemical “pockets” loaded with vancomycin. In 1 control animal, the catheters were polymer coated but without antibiotics. Animals were monitored for 9 to 11 days, after which the shunts were explanted. MRI was performed after shunt implantation and prior to catheter harvest. The catheters were sonicated prior to microbiological culture and also evaluated by electron microscopy. The animals’ brains were evaluated for histopathology.RESULTSAll animals underwent successful catheter implantation. The animals developed superficial wound infections, but no neurological deficits. Imaging demonstrated ventriculitis and cerebral edema. Harvested catheters from the control animal demonstrated > 104 colony-forming units (CFUs) of S. aureus. In the first experimental animal, one shunt demonstrated > 104 CFUs of S. aureus, but the other demonstrated no growth. In the second experimental animal, one catheter demonstrated no growth, and the other grew trace S. aureus. Brain histopathology revealed acute inflammation and ventriculitis in all animals, which was more severe in the control.CONCLUSIONSThe authors evaluated an animal model of ventricular shunting and reliably induced features of shunt infection that could be microbiologically quantified. With this model, investigation of pathophysiological and imaging correlates of infection and potentially beneficial shunt catheter modifications is possible.

Analisa Epidemiologi Kasus Helmintiasis pada Hewan Kurban di Kota Batu

Abstrack Eid of Adha is commemorated every 10 Dzulhijah followed by slaughtering a cattle, sheep or goat. That slaughter moment needed a lot of veterinarian to control animal health and meat inspection. The limitedness of personnel, therefore the Agriculture Office of Batu city cooperated with Faculty of Veterinary Medicine of Brawijaya University to supervise a slaughtering animals. The purpose of this research is to analys the prevalensi of fasciolosis on eid of adha in Batu City. Total number of slaughtering aninal in Batu City in 2017 were 679 cattle, 2357 goats and 2277 sheep. The research was conducted in 3 sub-districts in Batu City. Data were collected during postmortem examination in liver organ. The results showed that the total cases of heminthiasis in cattle were 22.97% (156 cases of fasciolosis from 679 cattle), cases of helminthiasis in goats 1.65% (39 cases of fascioloisis from 2357 goats), cases of helminthiasis in sheep 4.83% (80 cases of fasciolosis from 1658 sheep). Most cases of cattle fasciolosis occurred in Junrejo sub-district (31.54%), most cases of goats fasciolosis occurred in in Bumiaji sub-district (2.13%) and most cases of lambs fasciolosis occurred in Batu sub-district (7.19%). The slaughter animals come from Batu City, Malang Municipality and Blitar Municipality. From the data above, it is necessary to do the programs of giving worm medicine and animal health information especially for farmer. Cross-border coordination within the framework of an animal health healing program needs to be prepared to work together. Veterinary public health have responsibility to prepared a secure, healthy, a whole and halal meat in that slaughter moment. Kata kunci: Eid of Adha; Helminthiasis; Fasciolosis; Batu City;Food Safety Abstrak Idul Adha yang diperingati setiap tanggal 10 Dzulhijah diikuti dengan penyembelihan hewan kurban. Pemotongan yang serentak pada hari yang sama membutuhkan pengawasan kesehatan hewan dari dokter hewan berwenang dalam rangka memberikan jaminan keamanan pangan. Karena keterbatasan personel, maka Dinas Pertanian Kota Batu bekerjasama dengan Fakultas Kedokteran Hewan, Universitas Brawijaya dalam pengawasan pemotongan hewan kurban saat Idul Adha. Tujuan pengawasan tersebut antara lain untuk memantau penyakit hewan menular dan penyakit zoonotik. Pemotongan hewan kurban di Kota Batu tahun 2017 sebanyak 679 ekor sapi, 2357 kambing dan 2277domba. Tujuan dari analisis studi epidemiologi ini adalah untuk melihat berapa banyak kasus helmintiasis yang ditemukan pada hewan kurban yang ada di Kota Batu. Penelitian dilakukan dilakukan di 3 kecamatan di Kota Batu pada titik-titik pemotongan hewan dengan menggunakan data deskriptif dari kuisioner terstruktur. Data kasus fasciolosis diperoleh pada saat pemeriksaan postmortem pada organ hati. Hasil penelitian menunjukan bahwa total kasus fasciolosis pada sapi adalah 22,97% (156 kasus fasciolosis dari 679 ekor sapi), kasus fasciolosis pada kambing 1,65% (39 kasus fasciolosis dari 2357 ekor kambing), kasus fasciolosis pada domba 4,83% (80 kasus fasciolosis dari 1658 ekor domba). Kasus fasciolosis pada sapi terbanyak terjadi di Kecamatan Junrejo (31,54%), pada kambing yang terbanyak di Kecamatan Bumiaji (2,13%) dan pada domba yang terbanyak di Kecamatan Batu (7,19%). Hewan kurban berasal dari Kota Batu, Kabupaten Malang dan Kabupaten Blitar. Dari data diatas maka perlu dilakukan evaluasi mengenai program pemberian obat cacing dan pengasawan kesehatan hewan terutama untuk hewan kurban. Koordinasi lintas wilayah dalam rangka sinkronisasi program kesehatan hewan perlu dipersiapkan untuk dapat menyiapkan hewan kurban dan daging kurban yang aman, sehat, utuh, dan halal. Kata kunci: Idul Adha;Helmintiasis; Fasciolosis;Kota Batu;Keamanan Pangan

Leptospirosis

Leptospirosis is a leading zoonotic disease for morbidity and mortality in humans globally. Occupational health nurses should teach workers and the public about leptospirosis and the importance of disrupting the infection source through rodent control, animal vaccination, and flood prevention.

EVALUASI PENGATURAN DALAM PEMUNGUTAN RETRIBUSI DAERAH DI KABUPATEN LAMPUNG TENGAH

In conducting regional autonomy, the regional government needs funding, and one of the funding sources is regional retribution. Middle Lampung had provisioned 3 Regional Regulations which regulated retributions of common service, business service, and particular permit. Implementations of these three regional regulations could not yet be applied fully. The arrangement of retributions of telecommunication tower control, animal slaughter house, and advertising business permit had their own orientations. The regulation of retribution collection of telecommunication tower control was no longer in accordance with Decision of Constitutional Court number 46/PUU-XII/2014 on May 26th, 2015. The Regent Regulation about the conduct of retribution collection from animal slaughter house had not been yet provisioned, there was no qualified animal slaughter house and human resource. Regent Regulation about advertising business retribution collection had not been yet provisioned and there was no data of advertising business available as basics for collecting retribution. Keywords: Evaluation, Regulation, Retributions