Liquid Droplet Impact on a Sonically Excited Thin Membrane

Impacting droplet characteristics on hydrophobic surfaces can be altered by introducing surface oscillations. Impacting water droplet contact duration, spreading, retraction, and rebounding behaviors are examined at various sonic excitation frequencies...

Design and Fabrication of Pneumatically Actuated Valveless Pumps

In this study, a valveless pump was successfully designed and fabricated for the purpose of medium transportation. Different from traditional pumps, the newly designed pump utilizes an actuated or a deflected membrane, and it serves as the function of a check valve at the same time. For achieving the valveless property, an inlet or outlet port positioned in an upper- or lower-layer thin membrane was designed to be connected to an entrance or exit channel. Theoretical analysis and numerical simulation were conducted simultaneously to investigate the large deformation characteristics of the membranes and to determine the proper location of the inlet or outlet port on the proposed pump. Then, the valveless pump was fabricated on the basis of the proposed design. In the experiment, the maximum flow rate of the proposed pump exceeded 12.47 mL/min at a driving frequency of 5.0 Hz and driving pressure of 68.95 kPa.

Pattern transfer of large-scale thin membranes with controllable self-delamination interface for integrated functional systems

Direct transfer of pre-patterned device-grade nano-to-microscale materials highly benefits many existing and potential, high performance, heterogeneously integrated functional systems over conventional lithography-based microfabrication. We present, in combined theory and experiment, a self-delamination-driven pattern transfer of a single crystalline silicon thin membrane via well-controlled interfacial design in liquid media. This pattern transfer allows the usage of an intermediate or mediator substrate where both front and back sides of a thin membrane are capable of being integrated with standard lithographical processing, thereby achieving deterministic assembly of the thin membrane into a multi-functional system. Implementations of these capabilities are demonstrated in broad variety of applications ranging from electronics to microelectromechanical systems, wetting and filtration, and metamaterials.

Investigation of the bag-breakup phenomena of the spray generation processes during wind-wave interaction in the laboratory experiments with optical methods

Present paper devoted to the investigations with optical methods processes of artificially induced bag-breakup type of spray formation phenomenon within wind-wave interaction. Experiments were carried out on the Thermostratified Wind-Wave Tank of the IAP RAS. High-speed video filming with the shadow imaging method demonstrated that it was possible to artificially reproduce all the main stages of this phenomenon, which are also observed for the sporadically occurred ones: inflation of a thin membrane surrounded by a thicker rim, rupture of the membrane leading to the formation of small droplets, fragmentation of the rim with the formation of large droplets. Special processing of the images allowed us to estimate typical lifetimes and sizes of membrane for artificial bag-breakup events which turned out to be close to the same parameters for sporadically occurred ones.

Calling the Amino Acid Sequence of a Protein/Peptide from the Nanospectrum Produced by a Sub-nanometer Diameter Pore

The blockade current that develops when a protein translocates across a thin membrane through a sub-nanometer diameter pore (i.e., a nanospectrum) informs with extreme sensitivity on the sequence of amino acids that constitute the protein. Whereas mass spectrometry (MS) is still the dominant technology for protein identification, it suffers limitations. In proteome-wide studies, MS fails to sequence proteins de novo, but merely classifies a protein and it is not very sensitive requiring about a femtomole to do that. Compared with MS, a sub-nanometer diameter pore (i.e. a sub-nanopore) directly reads the amino acids constituting a single protein molecule, but efficient computational tools are still required for processing and interpreting the blockade current. Here, we delineate computational methods for processing sub-nanopore nanospectra and predicting electrical blockade currents from protein sequences, which are essential for protein identification.

Nanopore Technology and Its Applications in Gene Sequencing

In recent years, nanopore technology has become increasingly important in the field of life science and biomedical research. By embedding a nano-scale hole in a thin membrane and measuring the electrochemical signal, nanopore technology can be used to investigate the nucleic acids and other biomacromolecules. One of the most successful applications of nanopore technology, the Oxford Nanopore Technology, marks the beginning of the fourth generation of gene sequencing technology. In this review, the operational principle and the technology for signal processing of the nanopore gene sequencing are documented. Moreover, this review focuses on the applications using nanopore gene sequencing technology, including the diagnosis of cancer, detection of viruses and other microbes, and the assembly of genomes. These applications show that nanopore technology is promising in the field of biological and biomedical sensing.

Ultrastiff graphene

Graphene has exceptionally high in-plane strength, which makes it ideal for various nanomechanical applications. At the same time, its exceptionally low out-of-plane stiffness makes it also flimsy and hard to handle, rendering out-of-plane structures unstable and difficult to fabricate. Therefore, from an application point of view, a method to stiffen graphene would be highly beneficial. Here we demonstrate that graphene can be significantly stiffened by using a laser writing technique called optical forging. We fabricate suspended graphene membranes and use optical forging to create stable corrugations. Nanoindentation experiments show that the corrugations increase graphene bending stiffness up to 0.8 MeV, five orders of magnitude larger than pristine graphene and corresponding to some 35 layers of bulk graphite. Simulations demonstrate that, in addition to stiffening by micron-scale corrugations, optical forging stiffens graphene also at the nanoscale. This magnitude of stiffening of an atomically thin membrane will open avenues for a plethora of new applications, such as GHz resonators and 3D scaffolds.