DETERMINATION OF OPERATIONAL RELIABILITY INDICATORS OF AVIATION EQUIPMENT TAKING INTO ACCOUNT ICAO RECOMMENDATIONS

On the basis of the developed technique for estimation of aviation equipment reliability indicators, the results of determination of orientating reliability indicators of helicopters and their functional systems are presented. The list and the main reasons for the change of reliability indicators for 2016–2020 are determined.

Pattern transfer of large-scale thin membranes with controllable self-delamination interface for integrated functional systems

Direct transfer of pre-patterned device-grade nano-to-microscale materials highly benefits many existing and potential, high performance, heterogeneously integrated functional systems over conventional lithography-based microfabrication. We present, in combined theory and experiment, a self-delamination-driven pattern transfer of a single crystalline silicon thin membrane via well-controlled interfacial design in liquid media. This pattern transfer allows the usage of an intermediate or mediator substrate where both front and back sides of a thin membrane are capable of being integrated with standard lithographical processing, thereby achieving deterministic assembly of the thin membrane into a multi-functional system. Implementations of these capabilities are demonstrated in broad variety of applications ranging from electronics to microelectromechanical systems, wetting and filtration, and metamaterials.

Aircraft maintenance system simulation mathematical model construction

The development of the aviation transport system is characterized by sophistication of interacting objects, the multi-criteria nature of the tasks to be solved and difficulties in making management decisions. For example, modern medium haul aircraft are fitted with up to 25,000 sensors to monitor the performance capabilities of functional systems components. Numerous ground-based instrumental methods and means of diagnosing the technical condition are used. This requires the development of methods and algorithms for determining and monitoring the criteria of limiting state of the monitored components and functional systems of aeronautical equipment. In this regard, analytical models of predictive estimate for the technical condition of aeronautical equipment, determination of aircraft maintenance modes and provision of spare parts and materials become essential. The paper proposes a scheme of the aircraft fleet maintenance system modeling algorithm and deducing the mathematical model of the optimal number of aircraft states in order to exclude secondary and subjective factors. The method of statistical modeling based on Markov processes with discrete states and continuous time is the basis of the proposed analytical model. The proposed method is reduced to the synthesis of some modeling algorithm of the investigated process that simulates the complex system components behavior and interaction as well as random perturbing factors. A distinctive feature of the presented algorithm is determination of the predominant estimated dependences of transition probabilities and intensities taking into account the requirements of the modern regulatory framework in terms of reliability of equipment and diagnosing the technical condition. The analysis of the predominant estimated dependencies study results in the conditions of operation of the aircraft maintenance system confirmed a high degree of correlation of the time duration effect on the particular states in order to diagnose the technical condition depending on the diagnostic concept. The proposed simulation model can be used for the aircraft technical condition predictive estimate, aircraft gas turbine engines and functional systems.

Human-Centric Functional Modeling and the Unification of Systems Thinking Approaches

Where systems thinking approachesare often different and sometimes irreconcilable because they are based on the reasoning of one individual or another, Human-Centric Functional Modeling aims to become universal through looking inwards to the way all human beings perceive. HCFM provide a methodology that enables first person observations within each of the senses of the body or within the emotions, mind, or consciousness as functional systems to be represented as forming mathematical spaces that in turn enable all possible systems thinking approaches to be represented.This creates the possibility of comparing all systems thinking approaches to determine which is most “fit” in each context in which it is used, and it radically reduces the barriers to reusing the best components of each approach.

Atypical Integration of Sensory-to-Transmodal Functional Systems Mediates Symptom Severity in Autism

A notable characteristic of autism spectrum disorder (ASD) is co-occurring deficits in low-level sensory processing and high-order social interaction. While there is evidence indicating detrimental cascading effects of sensory anomalies on the high-order cognitive functions in ASD, the exact pathological mechanism underlying their atypical functional interaction across the cortical hierarchy has not been systematically investigated. To address this gap, here we assessed the functional organisation of sensory and motor areas in ASD, and their relationship with subcortical and high-order trandmodal systems. In a resting-state fMRI data of 107 ASD and 113 neurotypical individuals, we applied advanced connectopic mapping to probe functional organization of primary sensory/motor areas, together with targeted seed-based intrinsic functional connectivity (iFC) analyses. In ASD, the connectopic mapping revealed topological anomalies (i.e., excessively more segregated iFC) in the motor and visual areas, the former of which patterns showed association with the symptom severity of restricted and repetitive behaviors. Moreover, the seed-based analysis found diverging patterns of ASD-related connectopathies: decreased iFCs within the sensory/motor areas but increased iFCs between sensory and subcortical structures. While decreased iFCs were also found within the higher-order functional systems, the overall proportion of this anomaly tends to increase along the level of cortical hierarchy, suggesting more dysconnectivity in the higher-order functional networks. Finally, we demonstrated that the association between low-level sensory/motor iFCs and clinical symptoms in ASD was mediated by the high-order transmodal systems, suggesting pathogenic functional interactions along the cortical hierarchy. Findings were largely replicated in the independent dataset. These results highlight that atypical integration of sensory-to-high-order systems contributes to the complex ASD symptomatology.

Biomaterials Development for Application in Tissue Engineering: Literature Review

The search for tissue regeneration has attracted a lot of attention due to its wide applicability, and great potential to solve several problems in advanced therapies. Currently, functional systems have been widely used as therapeutic solutions in the treatment of some skin diseases, whether chronic, acquired, or as a consequence of accidents and burns. It is possible due to the feasibility of releasing and/or acting in loco of some active substances with properties and characteristics very similar to human skin. In this sense, this work aimed to carry out a literature review research regarding the development of new biomaterials, including hydrated membranes composed of biopolymers such as keratin and bacterial cellulose.