Urchin-like hollow SiO2@γ-MnO2 microparticles for the rapid degradation of organic dyes

In this paper, using hollow silica microspheres as carrier, we developed a facile method for preparation of a novel kind of hollow urchin-like SiO2@γ-MnO2 microparticles with excellent performance for rapid oxidation degradation of organic dyes.

How Organic Substances Promote the Chemical Oxidative Degradation of Pollutants: A Mini Review

The promotion of pollutant oxidation degradation efficiency by adding organic catalysts has obtained widespread attention in recent years. Studies have shown that organic substances promote the process of traditional oxidation reactions by accelerating the redox cycle of transition metals, chelating transition metals, activating oxidants directly to generate reactive oxygen species such as hydroxyl and sulfate radical, or changing the electron distribution of the target pollutant. Based on the promotion of typical organic functional groups on the chemical oxidative process, a metal-organic framework has been developed and applied in the field of chemical catalytic oxidation. This manuscript reviewed the types, relative merits, and action mechanisms of common organics which promoted oxidation reactions so as to deepen the understanding of chemical oxidation mechanisms and enhance the practical application of oxidation technology.

DEVELOPMENT OF HPLC STABILITY DEMONSTRATING METHODOLOGY FOR QUANTIFYING AZELNIDIPINE AND TELMISARTAN IN TABLETS AND BULK TYPES: VALIDATION FOLLOWING ICH DIRECTIVES

Objective: Azelnidipine (AZEL) and Telmisartan (TELM) combination is referred to the sufferers of hypertension. No analytical process has yet been mentioned for the TELM and AZEL combination analysis. We, therefore, have designed for its first time stability demonstrating methodology based on HPLC for analysing TELM and AZEL in the tablets and bulk. Methods: The assay of TELM and AZEL was get done on a 250 mm length C18 column (Supelco, 4.6 mm inner diameter, 5.0 μm particle size), and utilized 0.1M Na2SO4 (pH 3.6) and acetonitrile (55% volume: 45% volume) as the mobile solvents phase, at a stream rate 1.0 ml/min. HPLC recognition of TELM and AZEL was taken by a photodiode array sensor set at 258 nm. For validation of the stability demonstrating methodology proposed in terms of sensitivity, precision, specificity, linearity, device adequacy, robustness and accuracy, ICH directives were followed. Results: Calibration curves of TELM and AZEL were generated in the array of 20-60 µg/ml and 4-12 µg/ml with recovery percentage ranges of 99.62%-101.05% and 97.76%-100.17%, and detection limits of 0.020 µg/ml and 0.009 µg/ml, respectively. TELM and AZEL stability was inspected in the existence of acid, base, light, heat, and oxidation and it was realised to be more stable under oxidation degradation testing conditions employed when compared to acid, alkaline, photo, and heat degradation testing conditions applied. Conclusion: The observations demonstrated that the described HPLC stability demonstrating methodology was suitable for quantitating TELM and AZEL combination in tablets and bulk.