Potential of Tamanu (Calophyllum inophyllum) Oil for Atopic Dermatitis Treatment

Tamanu oil, derived from the nut of Calophyllum inophyllum L., has been traditionally used to treat various skin-related ailments. In recent years, this oil is increasingly gaining popularity as researchers continue to search for novel natural alternative therapies for various skin diseases. There have been a number of in vitro and in vivo studies investigating various skin-active properties of tamanu oil, and it has been proven to have potent anti-inflammatory, antioxidant, antimicrobial, analgesic, and even wound-healing abilities. These properties make tamanu oil an especially interesting candidate for the treatment of atopic dermatitis (AD). This multifaceted disease is marked by the disruption of the skin barrier function, chronic inflammation, and skin microbiome dysbiosis with limited treatment options, which is free from adverse events and inexpensive, making it desperate for a new treatment option. In this review, we examine previous in vitro and in vivo studies on AD-relevant pharmacological properties of tamanu oil in order to evaluate the potential of tamanu oil as a novel treatment option for AD.

Pelatihan Pembuatan Bahan Bakar Minyak Nyamplung (Calophyllum inophyllum) bagi Masyarakat Banyuwangi Jawa Timur

Seiring kenaikan konsumsi energi minyak dan menurunnya cadangan minyak bumi, maka perlu beralih ke minyak nabati sebagai sumber bahan bakar terbarukan, salah satunya adalah dari biji nyamplung. Biji nyamplung banyak terdapat di desa Kebondalem, Kecamatan Bangorejo, Kabupaten Banyuwangi. Pengabdian masyarakat ini bertujuan mengenalkan potensi minyak nyamplung ke masyarakat desa tersebut. Kegiatan pengabdian dilakukan oleh tim gabungan dosen dan mahasiswa jurusan Mesin, Fakultas Teknik, Universitas Jember. Kegiatan berupa pengenalan potensi biji nyamplung untuk alternative bahan bakar, dilanjutakn dengan peragaan pengepresan biji menjadi minyak. Di sela-sela kedua acara teresbut diselingi tanya jawab dan diskusi. Hasil dari pengabdian ini cukup membuka wawasan warga desa yang hadir akan potensi nyamplung yang selama ini terabaikan. Tokoh masyarakat dan karang taruna siap untuk menindaklanjuti kegiatan ini dengan rencana penanaman lahan hutan desa dengan nyamplung. Perlu arahan dan kegiatan lanjutan untuk menyambut antusiasme warga desa ini.

Acid Value Reduction of Calophyllum inophyllum Oil by Oilseeds In situ Esterification Using Sulfuric Acid Catalyzed Methanol and Isopropyl Alcohol Mixture

Non-edible oilseed can be used in biodiesel preparation as a low-cost feedstock. However, it contains a high free fatty acid or a high acid value, which causes a problematic biodiesel reaction. The investigation of acid value reduction of Calophyllum inophyllum oilseed by in situ esterification using sulfuric acid-catalyzed methanol and isopropyl alcohol has been conducted. Calophyllum inophyllum oil was extracted by n-hexane in the Soxhlet apparatus to determine the oil content. In situ esterification using methanol-isopropyl alcohol and the sulfuric acid as a catalyst was carried out in a reflux three-neck rounded bottom flask batch process to decrease free fatty acid or acid value. Four independent reaction variables, including the ratio of mixture volume to seed weight, the ratio of methanol to mixture volume, catalyst percentage, and reaction time, were varied. The experiments utilized by the response surface methodology with central composite design configuration to obtain the optimum conditions. The oil content of Calophyllum inophyllum oilseed extraction was 57.94% and an acid value was 90.38 mg KOH/g. The maximum esterified oil yield of 91.00% and 3.81 mg KOH/g minimum acid value were achieved in the optimum reaction conditions.

Corrigendum: Antioxidant assessment of characterised essential oils from Calophyllum inophyllum Linn using 2,2-diphenyl-1- picrylhydrazyl and hydrogen peroxide methods

No abstract available.