Analysis of Genres of the BBC One TV Programs

The relevance of the study is based on the fact that the BBC One channel is interesting as an example of a public service broadcaster which retains its image and competitiveness on the global media market. The goal of the research is to analyze the BBC One programming with regard to its forms of journalists and cameramens work. The semiotic methodology is chosen for interpreting sign systems, i. e. journalists texts or TV frames, as interconnected phenomena of culture. As a result, important sociocultural and philosophical elements integrated into the BBC One programming and determining its genre profile have been revealed. The social mission of the public broadcasting, combination of regional and metropolitan grounds, the prevalence of serious news genres are among them. Moreover, the programs are open for entertaining content including a foreign-made one. There is also a visual and aesthetic adaptation of pre-TV cultural forms of theater and the tabloid press, etc. Therefore, we can speak of a rather flexible programming policy of the BBC One, which can be a good model to develop strategies for public service broadcasters in other countries.

Parallel encryption of input and output data for HPC applications

A methodology for protecting confidential data sets on third-party HPC systems is reported. This is based on the NIST AES algorithm and supports the common ECB, CTR and CBC modes. The methodology is built on a flexible programming model that delegates management of the encryption key to the application code. The methodology also includes a fine-grain control over which arrays on the files are encrypted. All the stages in an encrypted workflow are investigated using an established CFD code. Benchmarks are reported using the UK national supercomputer service (ARCHER) running the CFD code on up to 18,432 cores. Performance benchmarks demonstrate the importance of the way the encryption metadata is treated. Naïve treatments are shown to have a large impact on performance. However, through a more judicious treatment, the time to run the solver with encrypted input and output data is shown to be almost identical to that with plain data. A novel parallel treatment of the block chaining in AES-CBC mode allows users to benefit from the avalanche properties of this mode relative to the CTR mode, with no penalty in run-time.

Precise genomic deletions using paired prime editing

Technologies that precisely delete genomic sequences in a programmed fashion can be used to study function as well as potentially for gene therapy. The leading contemporary method for programmed deletion uses CRISPR/Cas9 and pairs of guide RNAs (gRNAs) to generate two nearby double-strand breaks, which is often followed by deletion of the intervening sequence during DNA repair. However, this approach can be inefficient and imprecise, with errors including small indels at the two target sites as well as unintended large deletions and more complex rearrangements. Here we describe a prime editing-based method that we term PRIME-Del, which induces a deletion using a pair of prime editing gRNAs (pegRNAs) that target opposite DNA strands, effectively programming not only the sites that are nicked but also the outcome of the repair. We demonstrate that PRIME-Del achieves markedly higher precision in programming deletions than CRISPR/Cas9 and gRNA pairs. We also show that PRIME-Del can be used to couple genomic deletions with short insertions, enabling deletions whose junctions do not fall at protospacer-adjacent motif (PAM) sites. Finally, we demonstrate that lengthening the time window of expression of prime editing components can substantially enhance efficiency without compromising precision. We anticipate that PRIME-Del will be broadly useful in enabling precise, flexible programming of genomic deletions, including in-frame deletions, as well as for epitope tagging and potentially for programming rearrangements.

Software for Interactive and Collaborative Creation in the Classroom and Beyond: An Overview of the Soundcool Software

This article presents a free framework for collaborative creation of interactive and experimental computer music called Soundcool. It is designed to fill a gap between rigid ready-to-use applications and flexible programming languages. The system offers easy-to-use elements for generating and processing sound, much like ready-made applications, but it enables flexible configuration and control, more like programming languages. The system runs on personal computers with an option for control via smartphones, tablets, and other devices using the Open Sound Control (OSC) protocol. Originally developed to support a new music curriculum, Soundcool is being used at different educational institutions in Spain, Portugal, Italy, and Romania through EU-funded Erasmus+ projects. In this article, we present our system and showcase three different scenarios as examples of how our system meets its objectives as an easy-to-use, versatile, and creative tool.

An Analysis of College Choice Information Provided on Graduate Program Websites: Implications for Improving Applicant Diversity in Educational Measurement

There has long been a concern about the lack of representation of ethnic minorities in the field of educational measurement. As previous research has shown that graduate programs primarily rely on their websites for recruiting efforts, the objective of this study was to conduct a content analysis of all U.S. educational measurement program websites to evaluate the availability of college choice information found to be useful for underrepresented ethnic minority applicants. In terms of program climate, results revealed that less than 10% of programs directly encouraged ethnic minorities to apply or included an anti-discrimination statement in regards to application review on their websites. Moreover, only a few program websites indicated the availability of flexible programming – previously found to be important for underrepresented ethnic minority students – such as part-time options (16%), evening courses (10%), and online course/program availability (8%). Recommendations for how measurement programs can improve their websites to include desirable college choice information for underrepresented ethnic minority applicants is discussed.

Data Visualization Strategies for Computer Simulation in Bioelectromagnetics

Bioelectromagnetics is a branch of science that examines how living organisms interact with electromagnetic fields. In a broader sense, it is a discipline that spans the fields of signal processing, electromagnetics, medical imaging, physiology, medical physics, anatomy, occupational and environmental health, behavioral, and computer sciences. Due to its provision of interactive and flexible programming environment, this chapter describes a LabVIEW-based data visualization system that has been implemented and used in bioelectromagnetics simulations. The graphical nature of the LabVIEW programming environment makes it very easy to create a sophisticated application in a minimum amount of time, especially when compared to designing graphical user interfaces in a low-level programming language.