Tips for writers found in books, articles, blogs, and website forums often focus on the first sentence, engaging the reader to read the entire text. Tips for writing the first sentence are mostly applied to essays, including academic essays. On the other hand, good examples of the first sentence are usually chosen from classical literary works, making it possible to assume that the first sentence has meaning in every text, including a scientific article. The aim is to study and describe the first sentence in articles in various disciplines in the Latvian language to establish the connections between the recommendations on how to start the text and the actual language material. For the aim’s implementation, sentences from 848 scientific articles in Latvian (a total of 9700-word usage) are analyzed. The articles chosen for the study have been published between 2008 and 2018 in three branches and sub-branches of science: medical and health sciences, social sciences, humanities and arts. The main conclusions are as follows: the authors of Latvian scientific articles most often choose in the first sentence 1) to make a statement, 2) indicate the historical or geographical context, 3) define the main term used in the article. This is partly consistent with the suggestions given by writing instructors on the possible attractive content of the first sentence.