<p>The tropical Indian Ocean has warmed by 1 degree Celsius since the mid-twentieth century. This warming is likely to continue as the atmospheric carbon dioxide levels keep rising. Here, we discuss how the warming trend could influence the El Ni&#241;o Southern Oscillation (ENSO) via interaction with the Pacific and the Atlantic Ocean mean state and variability. The warming trend leads to the strengthening of easterlies in the western equatorial Pacific, subsequent downwelling and increase of the mixed later depth in the west, and an increase in the subsurface temperature gradient across the equatorial Pacific. In the eastern equatorial Pacific, the response of upwelling ocean currents to surface wind stress decreases, resulting in a weakening of ENSO amplitude. The Indian Ocean warming influences ENSO via the Atlantic Ocean as well. There, it is associated with the strengthening of equatorial easterly winds, and anomalous warming in the west and upwelling induced cooling in the east, especially in austral winter, during the peak of the Atlantic Ni&#241;o. Consequently, this results in a decrease of the amplitude of Atlantic Ni&#241;o events and weakening of the Atlantic Ni&#241;o-ENSO teleconnection, thereby hindering the transition of El Ni&#241;o events to La Ni&#241;a events. Thus, the Indian Ocean warming trend is found to modulate tropical Pacific and Atlantic mean state and variability, with implications for ENSO predictability under a warming climate.</p>