Spirit of the Place and the Place of the Spirit

Southwest Finnish folklore recorded in the early twentieth century contains a wealth of legends about local spirits, residing and acting both in the wilderness and on farm premises. They belong to belief systems that express social norms and regulations. Many of the legends contain enough information to allow us to locate exactly where local spirits are said to appear or interact with people. In this paper I study these locations and their place in the structure of village society, using historical village maps. The results shed new light on the nature of borders and boundaries in folklore and vernacular belief, as well as on the view of the social meaning of local spirits. Borders and border zones are common ground between several societies, lacking a clearly defined master. In places of uncertain mastery local spirits, endowed with taboos and the authority of the surrounding societies, play a social role in regulating the activities of people on such common ground.

Limits at the Limes. Diffracted Sovereignty inside the Border Zones

This paper questions state sovereignty at borders, by referencing the contradictions that a border control approach based upon security concerns creates, and the distortions between societies of norms and situations of exception that the European migration and asylum policies generate. Meanwhile, whilst sovereignty should correspond in a legal theory perspective to authority, its expressions manifested in the European borders consists essentially in domination as bare violence is deployed. By investigating the hiatus between how sovereignty ought to be in theory and how it is observed in practice, it is possible to consider that the very sovereignty is diffracted in the thickness of the frontiers (i). This paper explores the methods states develop directly or indirectly in the borders, inside the border zones, basing the analysis on the notion of heterotopia Michel Foucault forged. Such a conceptual tool is deployed in order to underscore how states construct and exploit frontiers as useful margins and establish them as dissolution zones. Three methods – extraction, classification and obliteration – are highlighted that correspond to the main purposes of border surveillance – control, selection and removal – (ii).

Syrian Displacement, Gender and Boundary-Making in the Turkish Borderlands

This article presents a reflexive ethnographic analysis of ‘refugee lives’ and borders and boundary-making in the Turkish borderlands. Since 2011, the humanitarian crisis as a result of the Syrian civil war, and the arrival at the European border zones of refugees crossing the Mediterranean, have occupied the news outlets of the world. Today the European Union and Turkey look for permanent ‘solutions’ and emphasize ‘integration’ as a durable response to forced migration. This essay explores reflexive dimensions of long-term-fieldwork with Syrian refugees at the Turkey-Syria border through an analysis of ethnographic encounters and the politics of belonging and place-making. Borders are often contested spaces that complicate the researcher’s positionality, which oscillates between a politically engaged subject position and the ‘stranger’ who encounters the ‘other’ and must negotiate her space. By examining the Turkish-Syrian border and Syrian refugees’ experiences in the border city of Antakya, this article offers a critical lens to view the identity and politics of the researcher and embodied geopolitics.

Knockdown of C3G Mitigates Post-Infarct Remodeling via Regulation of ERK1/2, Bcl-2 and Bax in Rat Myocardial Cells

Background: Cardiomyocyte-specific knockout of pro-survival integrin β1 subunit and its downstream components have been demonstrated to aggravate remodeling after myocardial infarction (MI). However, as a component of integrin pathway, it is unclear whether knockdown of pro-survival C3G (rap guanine nucleotide exchange factor 1) in cardiac myocytes and fibroblasts could have effect on myocardial remodeling. Methods and results: A rat model of MI was established by ligation of left anterior descending coronary artery. Infarcted myocardium and its border zones in Sprague-Dawley rats were transiently infected with C3G knockout lentivirus via local injection to knockdown C3G in the myocardium. Twelve weeks after injection with the lentiviruses, cardiomyocytic apoptosis and collagen in surviving myocardium, and left ventricle (LV) end-diastolic diameter were decreased, whereas LV weight / body weight ratio and LV ejection fraction were increased in MI group via down-regulation of pro-survival C3G, phosphorylated (p) ERK1/2 (phosphorylated extracellular regulated kinase 1/2) and Bcl-2 (B-cell lymphoma-2), and up-regulation of pro-apoptotic Bax in the surviving myocardium. On the other hand, treatment with the lentiviruses was found to delete C3G and diminish cell proliferation in vitro cardiac myocytic and fibroblastic cell lines respectively via down-regulation of p-ERK1/2 and Bcl-2, and up-regulation of Bax. Conclusions: Knockdown of pro-survival C3G in myocardium may mitigate surviving myocardial remodeling after MI, possibly through regulation of p-ERK1/2, Bcl-2 and Bax in vivo cardiac myocytes and fibroblasts.

Prenatal Trimethyltin Exposure Induces Long-Term DNA Methylation Changes in the Male Mouse Hippocampus

Trimethyltin (TMT) is an irreversible neurotoxicant. Because prenatal TMT exposure has been reported to induce behavioral changes, this study was conducted to observe gender differences and epigenetic changes using a mouse model. In behavioral testing of offspring at 5 weeks of age, the total times spent in the center, corner, or border zones in the male prenatal TMT-exposed mice were less than those of control unexposed mice in the open-field test. Female TMT-exposed mice scored lower on total numbers of arm entries and percentages of alternations than controls in the Y-maze test with lower body weight. We found that only TMT-exposed males had fewer copies of mtDNA in the hippocampus and prefrontal cortex region than controls. Additional epigenetic changes, including increased 5-methyl cytosine/5-hydroxymethyl cytosine levels in the male TMT hippocampus, were observed. After methylation binding domain (MBD) sequencing, multiple signaling pathways related to metabolism and neurodevelopment, including FoxO signaling, were identified by pathway analysis for differentially methylated regions (DMRs). Increased FOXO3 and decreased ASCL1 expression were also observed in male TMT hippocampi. This study suggests that sex differences and epigenetics should be more carefully considered in prenatal toxicology studies.

Liminality, Migration and Transgression in El Metro by Donato Ndongo-Bidyogo

My investigation aims to contribute to the understanding of the functionality of the fictitious border zones and how characters relate to spaces that put them in contact with the transitory, that is, liminal characters and spaces. In this sense I will work with the concept of liminality developed by anthropologists Arnold Van Gennep and Victor Turner. The object of study is El metro (2007), by Equatorial Guinean writer Donato Ndongo, and it is an example of the contemporary Equatoguinean novel in Spanish. My contribution focuses on how narrator and characters perceive and relate to liminal spaces (boats, beaches, the subway), and it touches upon the ambivalent relationship between the emigrant from sub-Saharan Africa and Western culture during the years of economic crisis in Spain.