PARAFFIN AS PHASE CHANGE MATERIAL FOR THERMAL ENERGY STORAGE, HEATING APPLICATION

Liberally accessible sun based vitality utilization for residential and mechanical applications are ruined since of its discontinuous nature. The thermal energy storage (TES) framework utilizing both sensible and inactive warm has numerous advantages like expansive warm capacity in a unit volume and its isothermal behavior amid the charging and releasing forms. Since of these focal points, in later a long time, a part of investigate work has been going on to overcome issues like moo warm exchange the rates between warm exchange liquid and stage alter fabric (PCM) in both charging and releasing forms of the PCM-based TES framework. In the present experimental investigation results of a combined sensible and latent heat TES system integrated with a varying (solar) heat source is presented. Investigations are carried out in the TES system for different phase change materials (paraffin) by varying HTF flow rates and for various paraffin mass (2, 4, and 6) kg. Experiments are performed charging processes. The results show that the 2 kg paraffin mass shows better performance compared to other paraffin mass.

Dropless penetrating keratoplasty using a subconjunctival dexamethasone implant: safety pilot study

Background/aimRejection is the main cause of graft failure after penetrating keratoplasty (PK). Its prevention by repeated instillation of steroid eye-drops has not evolved in decades. Poor adherence and discontinuous nature of eye-drop treatment may explain some PK failures. In a rabbit model, we previously demonstrated that a subconjunctival dexamethasone implant was well tolerated and prevented rejection efficiently in the first 5–6 weeks. This clinical trial investigates its tolerance and safety after PK.MethodsSingle-centre, phase II non-randomised tolerance and safety pilot study (NCT02834260). Designed to analyse the risk of elevated intraocular pressure (IOP), discomfort and resorption time. Fourteen patients with a low rejection risk indication of PK were enrolled between January 2017 and August 2018. The implant was injected in the 12 o’clock position, 5 mm from the limbus, at the end of PK. A steroid eye-drop treatment was planned when implant resorption was complete. Patients were monitored regularly for 12 months: IOP (main outcome measure at 1 month), discomfort and redness scores, implant status, rejection episode and central corneal thickness by optical coherence tomography. An independent data safety monitoring committee verified safety aspects.ResultsNo increase in IOP or other adverse event related to the implant was observed. Average resorption time was 6 weeks. The switch to steroid eye-drops was uneventful. One patient, included despite preoperative corneal neovascularisation (unintended protocol deviation) experienced a rejection.ConclusionsThis is the first proof of concept that dropless immunosuppression is possible after low rejection risk PK.Trial registration numberNCT02834260.

Characterization Of Human Stability Using Vector Acceleration Signals

Biomedical signals carry information about a physiological event. The part of the signal pertaining to a specific event is called an epoch. Once the event has been determined, the corresponding waveform may be segmented and analyzed based on many parameters[1]. As falls have increased in recent years due to an aging population, it is important to gain insight to the reaction of an individual to perturbations. One common method of studying human reaction is by using a balance aperture. This thesis describes the physical actions that produce acceleration on a balance apparatus and captures the acceleration on an accelerometer. Algorithms were developed to segment the unstable periods of the accelerometer signal. Wavelets were used as well as non-linear filters. The non-linear filters increased the amplitudes of periods of instability, simple signal models of the output of the non-linear filters where formulated and analyzed. Vector processing techniques were also developed. The experimental results demonstrate that the acceleration during unstable periods can be differentiated by its frequency content, by its discontinuous nature and by using vector relationships. The algorithms were tested with five individuals and had over 80% accuracy.

Characterization Of Human Stability Using Vector Acceleration Signals

Biomedical signals carry information about a physiological event. The part of the signal pertaining to a specific event is called an epoch. Once the event has been determined, the corresponding waveform may be segmented and analyzed based on many parameters[1]. As falls have increased in recent years due to an aging population, it is important to gain insight to the reaction of an individual to perturbations. One common method of studying human reaction is by using a balance aperture. This thesis describes the physical actions that produce acceleration on a balance apparatus and captures the acceleration on an accelerometer. Algorithms were developed to segment the unstable periods of the accelerometer signal. Wavelets were used as well as non-linear filters. The non-linear filters increased the amplitudes of periods of instability, simple signal models of the output of the non-linear filters where formulated and analyzed. Vector processing techniques were also developed. The experimental results demonstrate that the acceleration during unstable periods can be differentiated by its frequency content, by its discontinuous nature and by using vector relationships. The algorithms were tested with five individuals and had over 80% accuracy.

SARS-CoV-2 one year on: evidence for ongoing viral adaptation

SARS-CoV-2 is thought to have originated in the human population from a zoonotic spillover event. Infection in humans results in a variety of outcomes ranging from asymptomatic cases to the disease COVID-19, which can have significant morbidity and mortality, with over two million confirmed deaths worldwide as of January 2021. Over a year into the pandemic, sequencing analysis has shown that variants of SARS-CoV-2 are being selected as the virus continues to circulate widely within the human population. The predominant drivers of genetic variation within SARS-CoV-2 are single nucleotide polymorphisms (SNPs) caused by polymerase error, potential host factor driven RNA modification, and insertion/deletions (indels) resulting from the discontinuous nature of viral RNA synthesis. While many mutations represent neutral ‘genetic drift’ or have quickly died out, a subset may be affecting viral traits such as transmissibility, pathogenicity, host range, and antigenicity of the virus. In this review, we summarise the current extent of genetic change in SARS-CoV-2, particularly recently emerging variants of concern, and consider the phenotypic consequences of this viral evolution that may impact the future trajectory of the pandemic.

Supplemental Material: Progradational slope architecture and sediment distribution in outcrops of the mixed carbonate-siliciclastic Bone Spring Formation, Permian Basin, west Texas

<div>Figure S1: Location of six photopanels compiled along the outcrop overlaying the 3D textured model. Figure S2: West-facing outcrop between Shumard Canyon and Bone Canyon. Characteristics of slope detachment surfaces aid in correlating surfaces from Shumard to Bone Canyons. Note the discontinuous nature of the terrigenous sediment within Clinothem 4 from Shumard to Bone Canyons (also shown in Fig. 3B). Figure S3: Location of detailed outcrop photos shown in this publication.<br></div><div><br></div><div><br></div>

Supplemental Material: Progradational slope architecture and sediment distribution in outcrops of the mixed carbonate-siliciclastic Bone Spring Formation, Permian Basin, west Texas

<div>Figure S1: Location of six photopanels compiled along the outcrop overlaying the 3D textured model. Figure S2: West-facing outcrop between Shumard Canyon and Bone Canyon. Characteristics of slope detachment surfaces aid in correlating surfaces from Shumard to Bone Canyons. Note the discontinuous nature of the terrigenous sediment within Clinothem 4 from Shumard to Bone Canyons (also shown in Fig. 3B). Figure S3: Location of detailed outcrop photos shown in this publication.<br></div><div><br></div><div><br></div>

Chapter 54: Biology, Genetics and Evolution

In this Chapter we first look at the core view of the biology of language associated with Minimalism, including the Biolinguistics Program (section 2). Next, we consider research on the brain (section 3) and genetics (section 4), associated with this framework. Finally, we introduce some subsequent views of language evolution which break away from the saltationist, discontinuous nature of the mainstream approach (section 5), and draw some conclusions regarding future prospects (section 6).

SIMULATION OF THE INITIAL STAGE OF ENGINEERING NETWORK DESIGN

The work contains an analysis of the current state of centralized utilities, which form the basis of engineering networks in the country. The problems actualizing questions of mathematical modeling of system process of designing of new and reconstruction of old engineering networks in the conditions of their perspective development are resulted. The analysis of researches in the field of designing of engineering networks taking into account uncertainty of the information is given. The main material of the article is devoted to the construction of a mathematical model of the problem of distribution of work volumes at different stages of construction or reconstruction of the engineering network, taking into account the long-term development of the system. The list of questions to be answered when designing a network is given. A topological model of the design area is proposed. It consists of sites for which design is carried out, indicators of reliability of assignment of design sites to various stages of construction or reconstruction of an engineering network, quality criteria and characteristics of resource constraints. The basic mathematical model of the problem is built, which takes into account the conditions of perspective development of the engineering network. It is solved by Boolean programming methods. Another view of the introduced variables is offered, which allows to consider them as functions of belonging of sites of the territory of designing to this or that stage of construction or reconstruction of an engineering network. The introduction of indicators of reliability of the design sites to different stages of construction or reconstruction of the engineering network leads to the discontinuous nature of the allowable values of variables, which makes the task dichotomous. The solution to this problem is the problem of partial-integer linear programming. Another approach to taking into account the uncertainty of information at the initial stages of design of engineering networks – the use of algebra of interval numbers. With the help of interval numbers it is possible to reproduce the expert opinion on the scattering of the initial data. The analysis of efficiency of application of interval algebra is resulted and formulated the need for further research on this topic.

History of the Egyptian language

The history of the Egyptian language is both a linguistic and a cultural one. Considerable synchronic variation can be observed in the record, reflecting the various high-cultural and social settings and determinations of written performance in ancient Egypt at various times. Over the longue durée, Egyptian underwent a series of major typological changes, which, however, are only the overall results of a series of more minute changes following regular principles, paths, and mechanisms of linguistic change, such as grammaticalization. Current research is diverse: it strives for a more detailed description of linguistic change, concerns linguistic contacts with other languages, emphasizes the importance of synchronic variation of all sorts, and problematizes the partly discontinuous nature of the written record by which Egyptian, as a corpus language, presents itself.