Chest CT Usage in Covid-19 Pneumonia: Multicenter Study on Radiation Doses and Diagnostic Quality in Brazil

We assessed variations in chest CT usage, radiation dose and image quality in COVID-19 pneumonia. Our study included all chest CT exams performed in 533 patients from 6 healthcare sites from Brazil. We recorded patients’ age, gender and body weight and the information number of CT exams per patient, scan parameters and radiation doses (volume CT dose index—CTDIvol and dose length product—DLP). Six radiologists assessed all chest CT exams for the type of pulmonary findings and classified CT appearance of COVID-19 pneumonia as typical, indeterminate, atypical or negative. In addition, each CT was assessed for diagnostic quality (optimal or suboptimal) and presence of artefacts. Artefacts were frequent (367/841), often related to respiratory motion (344/367 chest CT exams with artefacts) and resulted in suboptimal evaluation in mid-to-lower lungs (176/344) or the entire lung (31/344). There were substantial differences in CT usage, patient weight, CTDIvol and DLP across the participating sites.

Establishment of national diagnostic reference levels (NDRL) for computed tomographic (CT) procedures in Sri Lanka: first nation-wide dose survey

The main purpose of this study was to establish the national diagnostic reference levels (NDRLs) for common CT procedures for the first time in Sri Lanka. Patient morphometric, exposure parameters, and dose data such as volume CT dose index (CTDIvol) and dose length product (DLP) were collected from 5666 patients who underwent 22 procedure types. The extreme dose values were filteblue before analysis to ensure that the data comes from standard size patients. The median of the dose distribution was calculated for each institution, and the third quartile value of the median distribution was consideblue as the NDRL. Based on the inclusion and exclusion criteria, 4592 patients data from 17 procedure types were consideblue for NDRL establishment covering 41\% of the country's total CT machines. The proposed NDRLs based on CTDIvol and DLP for non-contrast (NC) head:82.2 mGy/1556 mGy.cm, contrast-enhanced (CE) head: 82.2 mGy/1546 mGy.cm, chest-NC:7.4 mGy/350 mGy.cm, chest-CE:8.3 mGy/464 mGy.cm, abdomen NC:10.5 mGy/721 mGy.cm, abdomen arterial (A) phase:13.4 mGy/398 mGy.cm, abdomen venous (V) phase:10.8 mGy/460 mGy.cm, abdomen delay (D) phase:12.6 mGy/487 mGy.cm, sinus NC:30.2 mGy/452 mGy.cm, lumbar spine--NC:24.1 mGy/1123 mGy.cm, neck-NC:27.5 mGy/670 mGy.cm, high resolutions CT (HRCT) of chest:10.3 mGy/341 mGy.cm, kidney, ureter and bladder (KUB) NC:19.4 mGy/929 mGy.cm, chest to pelvis (CAP) NC:10.8 mGy/801 mGy.cm, CAP-A:10.4 mGy/384 mGy.cm, CAP-V:10.5 mGy/534 mGy.cm and CAP-D:16.8 mGy/652 mGy.cm. Although the proposed NDRLs are comparable with other countries, the observed broad dose distributions between the CT machines within the country indicate that dose optimisation strategies for Sri Lanka should be implemented for most of the CT facilities.

Reducing dose of Cone-Beam CT used for patient positioning in radiooncology

Cone-Beam computed tomography (CBCT) has become the most important component of modern radiotherapy for positioning tumor patients directly before treatment. In this work we investigate alternations to standard acquisition protocol, called preset, for patients with a tumor in the thoracic region. The effects of the changed acquisition parameters on the image quality are evaluated using the Catphan Phantom and the image analysis software Smári. The weighted CT dose index (CTDIW) is determined in each case and the effects of the different acquisition protocols on the patient dose are classified accordingly. Additionally, the clinical suitability of alternative presets is tested by investigating correctness of image registration using the CIRS thorax phantom. The results show that a significant dose reduction can be achieved. It can be reduced by 51% for a full rotation by adjusting the gantry speed. A more patientspecific uptake protocol for patients with laterally located tumor was created which allows a dose reduction of 54%.

Comparison study of image quality at various radiation doses for CT venography using advanced modeled iterative reconstruction

Objective We compared the image quality according to the radiation dose on computed tomography (CT) venography at 80 kVp using advanced modeled iterative reconstruction for deep vein thrombus and other specific clinical conditions considering standard-, low-, and ultralow-dose CT. Methods In this retrospective study, 105 consecutive CT venography examinations were included using a third-generation dual-source scanner in the dual-source mode in tubes A (reference mAs, 210 mAs at 70%) and B (reference mAs, 90 mAs at 30%) at a fixed 80 kVp. Two radiologists independently reviewed each observation of standard- (100% radiation dose), low- (70%), and ultralow-dose (30%) CT. The objective quality of large veins and subjective image quality regarding lower-extremity veins and deep vein thrombus were compared between images according to the dose. In addition, the CT dose index volumes were displayed from the images. Results From the patients, 24 presented deep vein thrombus in 69 venous segments of CT examinations. Standard-dose CT provided the lowest image noise at the inferior vena cava and femoral vein compared with low- and ultralow-dose CT (p < 0.001). There were no differences regarding subjective image quality between the images of popliteal and calf veins at the three doses (e.g., 3.8 ± 0.7, right popliteal vein, p = 0.977). The image quality of the 69 deep vein thrombus segments showed equally slightly higher scores in standard- and low-dose CT (4.0 ± 0.2) than in ultralow-dose CT (3.9 ± 0.4). The CT dose index volumes were 4.4 ± 0.6, 3.1 ± 0.4, and 1.3 ± 0.2 mGy for standard-, low-, and ultralow-dose CT, respectively. Conclusions Low- and ultralow-dose CT venography at 80 kVp using an advanced model based iterative reconstruction algorithm allows to evaluate deep vein thrombus and perform follow-up examinations while showing an acceptable image quality and reducing the radiation dose.

Evaluation of Direct Chest Circumference Measurement as an Efficient Tool in the Reduction of Radiation Dose in Multi-Slice Computerized Tomography of Chest- A Suggestion for Radiographers

Non-contrast computerized tomography (NCCT) is in rampant use in daily practice for the diagnosis of various chest diseases. In the era of COVID-19 pandemic, the use of chest NCCT has increased many fold. The reason was because it will resolve many issues and quick diagnosis can be made. The same was also required to see the behavior of the disease as well as in the follow-up. Basically two parameter are in use to described the amount of radiation dose received by the patient in volumetric CT. These are, one is CT Dose Index (CTDIvol) & its unit is mGy, and the second is dose length product (DLP). With normal pitch factor i.e. 1, the CTDIw is use on the description of CTDIvol. Multiplication of scan length and CTDIvol parameter is known as Dose Length Product (DLP). There was much concern about the radiation dose received by the individual. A total of twenty-six individuals were studied. The measurement of direct chest circumference before each CT chest examination and correlation of CT chest protocol parameter in combination use was an effective tool to reduce the amount of radiation dose in patients. Chest circumference values can also be correlated with body mass index (BMI) values for more accuracy in the reduction of radiation dose. Lower chest circumference patients should be irradiated with the least amount of radiation dose and so on.

Impact of additional mattresses in emergency CT on the automated patient centering proposed by a 3D camera: a phantom study

To assess the impact of the use of additional mattresses of different thicknesses on radiation dose and image noise based on the patient centering proposed by a 3D camera for CT. An anthropomorphic phantom was placed on mattresses of different thicknesses (from 3.5 to 13.5 cm) on the table of a CT scanner. The automated patient centering proposed by a 3D camera was analysed as a function of mattress thickness and corrected for table height. For this purpose, the impact on image noise in the lung tissues in the chest area and in the soft tissues in the abdomen-pelvis area, modulated mAs (mAsmod) by the tube current modulation system (TCM) and volume CT dose index (CTDIvol) was assessed slice-by-slice along the z-axis after CT scans. With the use of a mattress, the automated centering proposed by the 3D camera resulted in placement of the phantom above the isocentre. This incorrect positioning led to a significant increase in the mAsmod along the z-axis (p < 0.05) and in the CTDIvol. Image noise was significantly higher (p < 0.05) for automated phantom centering than with manual phantom centering. Differences of image noise between acquisitions with mattresses after automatic and manual phantom centering increased with the mattress thicknesses. The use of an additional mattress placed between the patient’s back and the table-top would require correcting the vertical centering proposed by the 3D camera. This manual correction is essential to avoid increased dose delivered to the patient and higher image noise.

Experimental Examination of Radiation Doses Of Dual- and Single-Energy Computed Tomography in Chest And Upper Abdomen in a Phantom Study

The aim of this phantom study is to examine radiation doses of dual- and single-energy computed tomography (DECT and SECT) in the chest and upper abdomen for three different multi-slice CT scanners. A total of 34 CT protocols were examined with the phantom N1 LUNGMAN. Four different CT examination types of different anatomic regions were performed both in single- and dual-energy technique: chest, aorta, pulmonary arteries for suspected pulmonary embolism and liver. Radiation doses were examined for the CT dose index CTDIvol and dose-length product (DLP). Radiation doses of DECT were significantly higher than doses for SECT. In terms of CTDIvol, radiation doses were 1.1–3.2 times higher, and in terms of DLP, these were 1.1–3.8 times higher for DECT compared with SECT. The third-generation dual-source CT applied the lowest dose in 7 of 15 different examination types of different anatomic regions.

Imaging pediatric acute head trauma using 100-kVp low dose CT with adaptive statistical iterative reconstruction (ASIR-V) in single rotation on a 16 cm wide-detector CT

OBJECTIVE: To demonstrate the ability of achieving low dose and high-quality head CT images for children with acute head trauma using 100 kVp and adaptive statistical iterative reconstruction (ASIR-V) algorithm in single rotation on a 16 cm wide-detector system. MATERIALS AND METHODS: We retrospectively analyzed the CT dose index (CTDI) and image quality of 104 children aged 0–6 years with acute head trauma (1 hour –3 days) in two groups: Group 1(n = 50) on a 256-row CT with single rotation at a reduced-dose of 100 kVp/240 mA and reconstructed using ASIR-V at 70%level; Group 2(n = 54) on a 64-row CT with multiple rotations at a standard dose of 120 kVp/ 180mA and reconstructed using a conventional filtered back-projection (FBP). Both groups used the 0.5 s/r axial scan mode. CT dose index (CTDI) and quantitative image quality measurements were compared using the Student t test; qualitative image quality comparison was carried out using Mann-Whitney rank test and the inter-reviewer agreement was evaluated using Kappa test. RESULTS: The exposure time was 0.5 s for Group 1 and 3.27±0.29 s for Group 2. The CTDI in Group 1 was 9.74±0.86mGy, 36.38%lower than the 15.31mGy in Group 2 (p < 0.001). Group 1 and Group 2 had similar artifact index (2.06±1.06 vs. 2.37±1.18) in the cerebellar hemispheres, and similar contrast-to-noise ratio (2.32±0.83 vs. 1.69±0.68), (1.47±0.72 vs. 1.10±0.43) respectively for cerebellum and thalamus (p > 0.05). Image quality was acceptable for diagnosis, and motion artifacts were reduced in Group 1 (p < 0.001). CONCLUSION: Single rotation CT with 100 kVp and 70%ASIR-V on 16 cm wide-detector CT reduces radiation dose and motion artifacts for children with acute head trauma without compromising diagnostic quality as compared with standard dose protocol. Thus, it provides a novel imaging method in management of pediatric acute head trauma.

Augmented reality improves procedural efficiency and reduces radiation dose for CT-guided lesion targeting: a phantom study using HoloLens 2

Out-of-plane lesions pose challenges for CT-guided interventions. Augmented reality (AR) headsets are capable to provide holographic 3D guidance to assist CT-guided targeting. A prospective trial was performed assessing CT-guided lesion targeting on an abdominal phantom with and without AR guidance using HoloLens 2. Eight operators performed a cumulative total of 86 needle passes. Total needle redirections, radiation dose, procedure time, and puncture rates of nontargeted lesions were compared with and without AR. Mean number of needle passes to reach the target reduced from 7.4 passes without AR to 3.4 passes with AR (p = 0.011). Mean CT dose index decreased from 28.7 mGy without AR to 16.9 mGy with AR (p = 0.009). Mean procedure time reduced from 8.93 min without AR to 4.42 min with AR (p = 0.027). Puncture rate of a nontargeted lesion decreased from 11.9% without AR (7/59 passes) to 0% with AR (0/27 passes). First needle passes were closer to the ideal target trajectory with AR versus without AR (4.6° vs 8.0° offset, respectively, p = 0.018). AR reduced variability and elevated the performance of all operators to the same level irrespective of prior clinical experience. AR guidance can provide significant improvements in procedural efficiency and radiation dose savings for targeting out-of-plane lesions.