Pustular psoriasis and arthropathy in a patient with HIV infection. Clinical case

The article presents a clinical case of pustular psoriasis and arthropathy in a patient with HIV infection. The diagnosis of psoriasis was confirmed by morphological examination. Signs of arthropathy were confirmed by X-Ray: presence of oligoarthritis of the distal interphalangeal joints of the fingers and feet was seen. Dactylitis severity ― 23 points, the Ritchie index ― 2, DLQI ― 28. The clinical course of psoriasis and its treatment in HIV-infected patients was considered after taking into account the data from literature and the patients current condition and observation. The above observation of a combination of several clinical forms of psoriasis (vulgar, pustular and arthropathy) in patients with HIV infection is an illustration of the features of the course and comorbidity of chronic dermatosis and AIDS, due to the influence of the infectious process, immunosuppression and ART. The development of pustular form and arthropathy creates the additional challenge of prescribing basic systemic treatment for severe and complicated psoriasis in an HIV-infected patient due to the presence of contraindications due to comorbidity. The glucocorticosteriod selected by the committee was effective on the skin and joint pathological processes, without having any negative impact on the course and treatment of the HIV infection. Such cases require further study and development of methods for the treatment of patients with comorbidity and their inclusion in an additional section in the clinical recommendations for the diagnosis and treatment of psoriasis.

Review of Wind Turbine Icing Modelling Approaches

When operating in cold climates, wind turbines are vulnerable to ice accretion. The main impact of icing on wind turbines is the power losses due to geometric deformation of the iced airfoils of the blades. Significant energy losses during the wind farm lifetime must be estimated and mitigated. Finding solutions for icing calls on several areas of knowledge. Modelling and simulation as an alternative to experimental tests are primary techniques used to account for ice accretion because of their low cost and effectiveness. Several studies have been conducted to replicate ice growth on wind turbine blades using Computational Fluid Dynamics (CFD) during the last decade. While inflight icing research is well developed and well documented, wind turbine icing is still in development and has its peculiarities. This paper surveys and discusses the models, approaches and methods used in ice accretion modelling in view of their application in wind energy while summarizing the recent research findings in Surface Roughness modelling and Droplets Trajectory modelling. An An additional section discusses research on the modelling of electro-thermal icing protection systems. This paper aims to guide researchers in wind engineering to the appropriate approaches, references and tools needed to conduct reliable icing modelling for wind turbines.

Space groups and crystallographic symmetry: writing a multi-featured tutorial in a new style

Knowledge of space groups and the implications of space group symmetry on the physical and chemical properties of solids are pivotal factors in all areas of crystalline solids. As Jerry Jasinski and I met to bring our ideas in teaching this subject to life, we both felt that `early and often' – teaching the concepts with textual and visual reinforcement, is the key to providing a sound basis for students in this subject. The tutorial contains > 200 PowerPoint `slides', in five modules, arranged by crystal class; a sixth module covers special topics. A `credits' module gives the direct addresses of all embedded links. Space-group diagrams appear in International Tables format. The triclinic and monoclinic groups (2 + 13) are built from `scratch', and are derived from the Hermann–Mauguin symbol. An additional section provides practice on many (but not all) of the orthorhombic groups in crystal class 222. Finally, a `Special Topics' section on enantiomorphous space groups features space groups P41 and P43. In the tutorial, lattice points build iteratively and interactively via keyclick, and the coordinates of points `pop up' as the unit cell is filled. We trust that the elements of guidance, inquiry and occasional humor will make the learning process enjoyable.

Update to U.S. National Response Team's Abandoned Vessels Authorities and Best Practices Guidance

The U.S. National Response Team promulgated an interagency guidance document entitled “Abandoned Vessel Authorities and Best Practices Guidance” (AVG) in 2014 to address a myriad of questions that the Federal On-Scene Coordinators and broader response community tend to face when mitigating threats caused by abandoned or derelict vessels. This document compiles information surrounding existing laws, policies, and best practices to inform and advise responders without bogging them down in “legalese” or forcing them to search from document to document to find all the relevant information. In the aftermath of the 2017 Atlantic Hurricane Season and associated responses, the National Response Team tasked its Preparedness Committee to reopen the 2014 AVG to ensure the document addressed the challenges that were brought to light amid the responses. The Committee chartered a working group to systematically review and update this document and incorporate the latest pertinent policy changes, including those from Federal Emergency Management Agency to ensure that it most thoroughly addressed the gamut of issues a responder may come up against in the arena of abandoned (or derelict, or displaced) vessel management. The updated AVG was completed and approved by the NRT in 2020 and is posted to the NRT website. Major updates include: Considerations for long-term storage and disposal;Clarification on foreign-flagged vessel nuances;Information for responders to consider regarding contaminants other than those covered under NCP/ESF constructs (e.g. if typical response authorities do not cover a scenario, what options might the responder still leverage);An additional section addressing nuances of managing multiple vessel casualties at once, either due to a natural disaster or an act or omission from a third party; andImportant differences between National Contingency Plan and Stafford Act funded/organized responses. This paper dives into the rationale for making changes, the benefits of additions made, the processes and methodologies for undertaking updates, and major elements of the AVG to provide a snapshot of the guidance it affords the reader.

Lineups

Lineups are conducted in the course of police investigations when a crime has been witnessed by one or more people. A lineup typically consists of a person whom the police believe committed the crime (i.e., the suspect) and some number of people who are known to be innocent of the crime (i.e., fillers). When the police have developed a suspect, they show witnesses a lineup to test whether they will claim that the suspect is the person who committed the crime (i.e., the perpetrator). If so, the witness is said to have made a positive identification of the suspect. What is not clear, at least in real-world investigations, is whether that identification is correct, because sometimes suspects are guilty and sometimes they are innocent. Since the late 1970s, psychologists have conducted experiments to find lineup procedures that decrease the likelihood that witnesses will mistakenly identify innocent suspects. These experiments are typically conducted in laboratory settings in which researchers expose participants to a simulated crime, often on videotape. After the participant-witnesses have viewed the crime, they are asked to attempt an identification from a lineup. In the laboratory, researchers can vary whether the perpetrator appears in that lineup. When the perpetrator is present in the lineup (i.e., a target-present lineup), the witness can identify the suspect (a correct identification), identify a filler, or say that the perpetrator is not there (an incorrect rejection of the lineup). When the perpetrator is not present (i.e., a target-absent lineup), the witness can make a mistaken identification of the suspect, identify a filler, or correctly reject the lineup. Using this method, researchers have identified lineup procedures that decrease mistaken identifications, which are the leading cause of wrongful convictions among those who have been exonerated by DNA tests conducted after trial. This article contains sections describing comprehensive General Overviews of research on lineups, research demonstrating that Live Lineups Are Equivalent to Photo Lineups, and Policy Recommendations and Best Practice Guidelines. The remaining sections describe many of these policy recommendations, including how Lineups Are Superior to Showups, having an Evidence-Based Suspicion for placing a suspect in a lineup, unbiased Lineup Composition, Double-Blind Administration, proper Lineup Instructions, collecting witnesses’ Confidence Statements in the accuracy of their identification immediately after the initial identification, Video Recording Identification Procedures, and avoiding Repeated Lineups. An additional section addresses special issues that need to be considered when Conducting Lineups with Children.

A Disorder of Sex Development in a Holstein–Friesian Heifer with a Rare Mosaicism (60,XX/90,XXY): A Genetic, Anatomical, and Histological Study

In this study, we describe an eighteen-month-old Holstein–Friesian heifer with a deformed vulva, located abdominally. The heifer showed typical signs of estrus. A comprehensive anatomical and histopathological examination revealed a blind-ended vagina and an additional section of urethra, which became a part of the shortened penis. Cytogenetic analysis showed the presence of two cell lines: 60,XX and 90,XXY. The frequency of the triploid cell line was low (3%) in leukocytes and elevated (35%) in fibroblasts. The molecular detection of Y-linked genes (SRY and AMELY) in the blood, skin, hair follicles, and buccal epithelial cells confirmed the presence of a cell line carrying the Y chromosome. Genotyping of 16 microsatellite markers in DNA isolated from hair follicles and fibroblast culture showed the presence of one (homozygous) or two variants (heterozygous) at all the studied loci, and allowed chimerism to be excluded. We concluded that the heifer had diploid/triploid (60,XX/90,XXY) mosaicism. To our knowledge, this is only the fifth such case to be reported worldwide in this species. Since cytogenetic studies are routinely performed on in vitro cultured leukocytes, we suspect that the prevalence of this chromosome abnormality is underestimated, as it is known from published reports that the frequency of the triploid cell line is usually very low in leukocytes.

Relationship between Fracture of the Ulnar Styloid Process and DRUJ Instability: A Biomechanical Study

Background There has been clinical question in the treatment of ulnar styloid fracture with distal radius fracture, surgical fixation of the styloid fragment, or ignorance of the fragment. We examined relationship between size of the ulnar styloid fracture and distal radioulnar joint (DRUJ) stability biomechanically to answer the above clinical question. Methods Changes in the dorsopalmar stiffness of the DRUJ after experimentally simulating in four types of ulnar styloid fractures were examined in cadavers. After tip, middle, base-horizontal, and base-oblique type of styloid fractures were made sequentially, changes in dorsopalmar DRUJ stiffness were measured using the MTS machine in the intact wrist, for each fracture, at 60 degrees pronation, neutral, and 60 degrees supination, respectively. Additional cutting of the radioulnar ligament (RUL) at the fovea was also simulated with the base-horizontal fracture. Results The tip and middle type fractures did not demonstrate significant loss of stiffness compared with the intact. The base-horizontal fracture demonstrated only significant loss of stiffness in the dorsal direction (radius palmar; ulnar dorsal) with forearm in neutral rotation. The base-oblique fracture demonstrated significant loss of dorsopalmar stiffness of the DRUJ. Additional section of the RUL with the base-horizontal fracture induced significant loss of stiffness of the DRUJ compared with the intact. Conclusions Because the RUL originates from the fovea as well as from the base of the ulnar styloid, these results suggest that DRUJ instability closely correlates with how much of the bony fragment includes the originating portions of the RUL. The findings further suggest that larger base-oblique and base-horizontal fragments with resultant DRUJ instability must be reattached, but that even base-horizontal fragment as well as tip and middle ulnar styloid fragment can be ignored when there is no instability.

ECONOMIC DOCTRINE OF RUSSIA: NODAL COMPONENTS AND NATIONAL PROJECTS

The article analyzes the requirements for strategic documents of a doctrinal nature that determine the main directions of the socio-economic development of Russia. The practicability of including an additional section in the macro-level doctrinal documents by analogy with the principles of forming socio-economic systems strategy at the micro-level is shown. Such a section in a concise form should reflect the planned system’s general vision, including its history, status, and conception of the future. The expediency of expanding the composition of national projects with the projects “Management” and “Enterprise” is justified. The first is intended to bring the system of regulation of the Russian economy in line with the imperatives of the domestic and world economy’s current state. The second is to determine government support’s key directions for developing an enterprise as the primary form of economic entities’ life activity.

Strength from Within

The chapter describes how young singers, female and male, can be helped as they traverse times of great vocal challenge. If psychological and emotional needs are not met, it is likely that adolescents will not endure vocal difficulties and will stop singing. Until coordination of the vocal mechanism returns, students must be provided with something to keep them going, to keep them from quitting singing. This chapter focuses on ideas of resolve that are essential to the navigation of voice change; perseverance is explored under the designations of grit, vulnerability, and relentlessness. An additional section considers perseverance in practice and provides strategies for music students and educators to utilize during voice change challenges and beyond.

The bioreactor with use of impeller mixers for cultivation of biomass of microalgas

Cultivation of microalgas gains popularity in the different countries in recent years. As a result of such intensive development of production the extensive experience in constructioning of various types of bioreactors was gained. The bioreactor for cultivation of microalgas having the cylindrical housing divided by horizontal partitions into sections for input and output of cultural liquid and additional section with an internal specular surface, the bubble device and gate stirrers fixed on blades, the rigidly bound to shaft is developed. Planetary rotation of gate stirrers concerning a shaft creates additional turbulization of the environment, provides alignment of concentration of cells of biomass, prevents emergence of hold-up spots, a premature deposition of cages of culture on the bottom of the device and increases efficiency of cultivation of microalgas. In the main section suspension of a microalga is exposed to the uniform light energy by means of coaxially established filament lamp of a daylight and to reflection of light from an internal specular surface of a housing. In the course of irradiating the filament lamp distinguishes warmth which is compensated by supply of the cooling air the Main difference from other bioreactors the impeller mixer fixed to a shaft in the bottom of a housing, preventing stratifying of the biomass pulp leaving more heavy is obespechivashchy full circulation of cultural liquid in the bottom of the device as in the horizontal, and vertical planes, at minimum mechanical energy consumptions. This device allows to create additional turbulization of the environment, to provide the uniform aeration, decrease in a power consumption on supply of steam-and-gas mixture in a collector, to prevent formation of "stagnant" zones in the bottom of the device.